Abstract Number: PB0708
Meeting: ISTH 2022 Congress
Background: Signs of bleeding include menorrhagia, epistaxis, hematuria, melena, easy bruising, soft tissue hematoma, hemarthrosis, and intracranial hemorrhage .
Aims: In this case, we presented a patient diagnosed in the neonatal period and hospitalized with recurrent rectal bleeding episodes .
Methods: ; It is aimed to draw attention to the importance of treatment compliance and that factor VII deficiency may cause level-independent bleeding.
Results: A 13-year-old female patient applied to the emergency service with the complaints of bloody stools and bruises on her legs this morning. In the patient’s history, it was learned that she was taking rFVIIa (Novoseven) twice a week with Factor VII deficiency. The patient had rectal bleeding accompanying abdominal pain at the age of 7 years. Novoseven treatment was given for 3 days. There was no pathology in intestinal examinations for rectal bleeding. At the age of nine,she presented to the emergency department with rectal bleeding again. Factor VII treatment was given at 30 µgr/kg every 4 hours on the first day, every 6 hours on the 2nd day, every 8 hours on the 3rd day, every 12 hours (5 days) on the following days, once a day (5 days). Gastroscopy revealed 3 ulcerated lesions in the distal sigmoid and rectum, and a white granulation tissue-like lesion in the ileum. Meckel scintigraphy were normal. Follow-up was planned in consultation with pediatric gastroenterology and pediatric surgery.
It was controlled with a proton pump inhibitor and intravenous hydration. She was discharged with prophylaxis treatment 3 days a week.
Conclusion(s): Each patient should be evaluated individually, taking into account the clinical history and the needs of the patient. Especially in patients with recurrent bleeding episodes, close follow-up and treatment plan become important.
To cite this abstract in AMA style:şahin ş, KHUDİYEVA S, UNUVAR A, TUGCU D, TANYILDIZ G, BILICI M, KARAKAS Z, KARAMAN S. A Case of Factor VII Deficiency Presented With Repeated Rectal Bleeding [abstract]. https://abstracts.isth.org/abstract/a-case-of-factor-vii-deficiency-presented-with-repeated-rectal-bleeding/. Accessed November 30, 2023.
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