Abstract Number: PB0776
Meeting: ISTH 2021 Congress
Menorrhagia is prevalent in 37% of adolescents and associated with co-morbidities like bleeding disorders (BD), iron deficiency anemia (IDA), and mood disorders. MCH is the first tertiary care centre in Ontario to start a multidisciplinary Young Women’s Blood Clinic (YWBC) staffed by a gynaecologist, hematologist, and nurse to provide diagnosis and management of menorrhagia.
The purpose of this study is to evaluate the prevalence of BD and IDA in adolescents (<18 years) with menorrhagia seen in YWBC. Additionally, management and outcomes will be reported.
This is a retrospective cohort study between July 2017 to June 2020. Patient records were reviewed for demographics, laboratory parameters, management plans, and outcomes.
80 new patients (mean age: 14.7 years) with menorrhagia were seen in the monthly YWBC during the study period. 4 patients were referred with pre-existing BDs (2 vWD, 1 factor XI deficiency, 1 factor VII deficiency), while 3/76 (4%) were newly diagnosed (3 vWD). On presentation, 25 (31%) had IDA, while 40 patients (51%) had iron deficiency without anemia. 54 patients were treated with oral iron alone, while 11 required IV iron and 10 required blood transfusion. Combined oral contraceptive pills were the most common management option, followed by tranexamic acid and IUD. After a median follow-up of 20.5 months, the majority of patients showed an improvement in menorrhagia.
Menorrhagia can be debilitating and requires coordinated multidisciplinary care to diagnose and manage adequately.
To cite this abstract in AMA style:Desai D, Joshi M, Upadhyay R, Costescu D, Bhatt M. A Retrospective Review of Diagnosis and Management of Heavy Menstrual Bleeding and Co-morbidities in Patients Seen in Young Women’s Blood Clinic [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/a-retrospective-review-of-diagnosis-and-management-of-heavy-menstrual-bleeding-and-co-morbidities-in-patients-seen-in-young-womens-blood-clinic/. Accessed December 7, 2021.
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