Abstract Number: PB0703
Meeting: ISTH 2021 Congress
Background: Disorders of collagen are known to be associated with a mild bleeding tendency, and generalised joint hypermobility is common in collagen disorders and can be objectively assessed with measures such as the Beighton score, with a score of 5 or more being positive for hypermobility. Previous studies have shown that the prevalence of hypermobility in a bleeding disorder clinic is approximately 24%, compared to control population prevalence of 2%.
Aims: Review proportion of patients with unexplained bleeding tendency or platelet defect who have been assessed for hypermobility with a Beighton score.
Methods: Review of Haemophilia Centre registry for all patients registered between 2015 and 2020 with a diagnosis of either a platelet defect or unexplained bleeding tendency, and comparison with records of Beighton score assessment.
Results: 146patients were registered to our haemophilia centre with a diagnosis of either platelet defect or unexplained bleeding tendency between 2015 and 2020. 26 (17.8%) of this total had been assessed with a Beighton score, and a total of 19 (13.0%) were found to have a current or historical Beighton score >/= 5. 77 patients were registered with a diagnosis of unexplained bleeding tendency, of which 19 (24.7%) were assessed with a Beighton score, and a total of 13 (16.9%) of the total were found to have a Beighton score >/= 5
Conclusions: Our data shows that there is an increased proportion of patients with a bleeding tendency with hypermobility compared to that expected in the normal population, roughly in line with other bleeding clinic prevalence, suggesting that an underlying collage disorder is common and may not be recognised as a contributor to a bleeding tendency, opening up potential for more routine assessment in this context.
To cite this abstract in AMA style:Clark J, Stephensen D, Dodd C, Elliott K. A Review of Beighton Scores Recorded for All Patients with a Bleeding Tendency Registered at One Haemophilia Centre without Another Formal Bleeding Disorder Diagnosis [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/a-review-of-beighton-scores-recorded-for-all-patients-with-a-bleeding-tendency-registered-at-one-haemophilia-centre-without-another-formal-bleeding-disorder-diagnosis/. Accessed September 29, 2023.
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