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An Assessment of the Cost-Effectiveness of Whole-Leg Ultrasound Scans Compared to Proximal Leg Vein Ultrasound Scans in the Diagnosis of Acute Deep Vein Thrombosis

G. Bertone1, Z. Lester2, H. Rowswell2, T. Nokes2, W. Thomas2

1University of Plymouth, Faculty of Health: Medicine, Dentistry & Human Sciences, Plymouth, United Kingdom, 2University Hospitals Plymouth NHS Trust, Plymouth, United Kingdom

Abstract Number: PB2270

Meeting: ISTH 2020 Congress

Theme: Venous Thromboembolism and Cardioembolism » VTE Diagnosis

Background: Guidelines from the National Institute of Clinical Excellence (NICE) suggest proximal leg vein ultrasound scans (USS) for patients with a suspected acute deep vein thrombosis (DVT), with a Wells score of 2 or more. If negative, a rescan of the proximal leg veins in 6-8 days is suggested. The guidelines recommend research into the cost-effectiveness of whole-leg USS compared with the current approach in the diagnosis of acute DVT.

Aims: To assess the cost-effectiveness of a whole-leg USS compared with proximal leg vein USS in the diagnosis of acute DVT.

Methods: We collected data on USS performed for the diagnosis of DVT. The data included the years 2002, 2003 and 2009, when proximal leg vein USS were primarily undertaken (~10% of scans by vascular sonographers did scan to the calf veins). We also collected data for years 2014 and 2015, in which whole-leg scans were primarily undertaken. The cost of an USS is estimated at £200. Our population is around 0.5 million.

Results: See Table 1. In 2002, 2003 and 2009 there were 1794 rescans performed which detected 72 DVT’s of which 19 (26%) were calf DVTs. For the year 2014 and 2015, only 385 rescans were performed which detected 22 DVT’s of which 5 (23%) were calf DVT’s. We calculated the cost of rescanning per annum to be £119,600 when primary scanning just involves the proximal veins (£4983 per +ve scan); whereas it is £38,500 when primary scanning involves the proximal and distal leg veins (£3500 per +ve scan).

Conclusions: We showed that performing a whole-leg scan as an initial diagnostic method does not drastically alter the percentage of DVTs detected at rescan, but it does allow a cost benefit. The reduction in the number of rescans performed suggests whole-leg scanning is a more cost-effective primary option.

Year 2002 2003 2009 2014 2015
Total number of first scans performed 852 989 1087 959 1000
Total number of positive DVT found (%) 203 (23.8) 223 (22.5) 223 (20.5) 175 (18.2) 180 (18.0)
Total number of calf DVT detected 17 16 16 9 27
Total number of rescans performed 576 665 553 202 183
Total number of positive DVT found (%) 28 (4.9) 30 (4.5) 14 (2.5) 13 (6.4) 9 (4.9)
Total number of calf DVT detected 7 5 7 2 3

[Table 1]

To cite this abstract in AMA style:

Bertone G, Lester Z, Rowswell H, Nokes T, Thomas W. An Assessment of the Cost-Effectiveness of Whole-Leg Ultrasound Scans Compared to Proximal Leg Vein Ultrasound Scans in the Diagnosis of Acute Deep Vein Thrombosis [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/an-assessment-of-the-cost-effectiveness-of-whole-leg-ultrasound-scans-compared-to-proximal-leg-vein-ultrasound-scans-in-the-diagnosis-of-acute-deep-vein-thrombosis/. Accessed October 1, 2023.

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