Background: Venous Thromboembolism (VTE) and neoplasms are closely related. Indeed, VTE can precede their discoveries as it can occur during their care.

Aims: The aim of our work was to study the relationship between these two diseases in a cohort of Tunisian patients.

Methods: We conducted a descriptive retrospective study of 19 years (from 2000 to 2018) in the internal medicine department of La Rabta Hospital. All patients who were hospitalized for VTE and whose etiological research revealed a neoplasm were included.

Results: Our study collected 207 patients with a sex ratio of 121/86. The average age was 63.2 years [19-90 years]. An age under 40 years was found on 6.8% of patients, while 50.7% of patients were over the age of 65 years. VTE was unusual in 86.5% of patients. Solid neoplasm was found in 78.3% of cases. VTE was indicative of neoplasm in 51.7% of cases. On these patients, the average diagnostic time for cancer was 1.45 months [0-15]. Among the patients already being followed for neoplasm, 19.2% were undergoing chemotherapy.
A recurrence of MVTE on antivitamins K was observed on 11 patients.

Conclusions: The occurrence of VTE in an elderly subject requires the search for a neoplasm especially when it is of unusual siege. This investigation must be redone at the slightest sign since the VTE may precede the neoplasm of a certain period of time. Cancer chemotherapy is an added risk factor.

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ISTH Congress Abstracts - https://abstracts.isth.org/abstract/aspects-of-cancer-related-venous-thrombosis-in-a-cohort-of-207-tunisian-patients/