Background: Catastrophic antiphospholipid antibody syndrome (APS) is an autoimmune disorder and an important cause of acquired thrombophilia. APS causes an increased risk for vascular thrombosis. It is common in the fourth decade of life and in females. Its most severe form is Catastrophic Antiphospholipid syndrome. The case highlights a rare presentation of multiple thrombosis at three different sites in a 28-year-old male diagnosed with catastrophic antiphospholipid syndrome, and underwent lifesaving surgery with pulmonary thromboendarterectomy. The case also stresses the importance of recognizing a hypercoagulable state as the cause of thrombosis and the important implication on the therapeutic management.

Aims: This report highlights the importance of prompt recognition and diagnosis, and therapeutic implications to prevent irreversible complications related to its devastating prognosis.

Methods: “.”

Results: “.”

Conclusion(s): The case highlights the importance of recognizing CAPS in a young male presenting with VTE – emphasizing auto-immune disease as a cause of hypercoagulable state in pulmonary embolism because of its high mortality rate and its implication on therapeutic management.

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Catastrophic Antiphospholipid syndrome in a 28 year old male presenting with multiple thrombi at three different sites

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Catastrophic Antiphospholipid syndrome in a 28 year old male presenting with multiple thrombi at three different sites with persistently elevated antiphospholipid antibodies

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ISTH Congress Abstracts - https://abstracts.isth.org/abstract/catastrophic-antiphospholipid-syndrome-in-a-28-years-old-male-a-case-report/