Abstract Number: PB1330
Meeting: ISTH 2022 Congress
Theme: Venous Thromboembolism » VTE Epidemiology
Background: Venous thromboembolism (VTE) is an increasingly recognised condition due to improved radiological visualisation and clinical recognition; however, real-life experience differs between countries. VTE is still associated with significant mortality.
Aims: We aimed to assess VTE-related temporal trends in a tertiary hospital patient cohort.
Methods: The prospective cohort study, conducted in a single university hospital from 2014 till 2021, included patients ≥18 years presenting with symptomatic acute VTE. Statistical analyses were conducted using SPSS 23.0.
Results: Between 2014 and 2021 a total of 648 patients were admitted to the hospital with VTE. In 2014-2017 in comparison to 2018-2021, body mass index, patient age did not differ in patients with VTE, and had no impact on mortality (p>0.05).
In total, 19.4% of patients were diagnosed with cancer, with trend to increase in last years among patients with VTE (p < 0.05). During follow-up 52.3% (n=66) of patients with cancer died, 30-day mortality was 37.9% (n=25), 1-year mortality was 89.4%.
Out of 648 patients 172 died, 30-day mortality was 40.1%, impact of cancer on mortality (p < 0.05).
Episode of VTE after surgical operation was observed in 11% of patients that were admitted to the hospital with no significant decrease in incidence in last years and no impact on mortality (p>0.05). Thromboprophylaxis after surgery was not prescribed to 70.4% of patients. Immobility before episode of PE was noted in 15.6% of patients.
Pulmonary artery systolic pressure >50 mmHg on echocardiography was noticed in 21.3% or 66 patients, only 2% of patients revealed CTEPH confirmed by right heart catheterisation after episode of VTE.
Conclusion(s): Mortality of VTE might be high due to advanced stage of concomitant diseases. Long-term complications of VTE are underevaluated.
Funding: Support for involving doctoral students in scientific research and studies. Project/agreement No.8.2.2.0/20/I/004
To cite this abstract in AMA style:
Kigitovica D, Gibietis V, Rusa E, Strautmane S, Zaicenko A, Dzirnieks K, Birzulis J, Skride A. Characteristics and trends of venous thromboembolism – local experience [abstract]. https://abstracts.isth.org/abstract/characteristics-and-trends-of-venous-thromboembolism-local-experience/. Accessed March 21, 2024.« Back to ISTH 2022 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/characteristics-and-trends-of-venous-thromboembolism-local-experience/