Abstract Number: PB0644
Meeting: ISTH 2021 Congress
Theme: Hemophilia and Rare Bleeding Disorders » Hemophilia - Clinical
Background: Prophylaxis treatment for Severe Hemophilic patients has been implemented in Brazil since 2011. Its implementation logistics used the system organized by the Ministry of Health (MoH) two years before: – the national registry of patients with inherited coagulopathies and other bleeding disorders, Hemovida Web Coagulopatias* (HWC). The HCW registry compiles profile of patients, diagnosis, treatments and complications (http://coagulopatiasweb. datasus.gov.br).
Aims: The consistency analysis for validation of the data regarding hospitalizations among hemophilic patients from the HC FMUSP. They were hospitalized in the in Public Hospitals from the Health Secretary of the São Paulo State (SES-SP).
Methods: Amid patients with Hemophilia, registered at HWC as under treatment at FMUSP (n=267), 92% (n=246) were followed from 2008 to 2018, and 30% were hospitalized (n= 73) according to the SES-SP registries. The consistency analysis applied data validation through current HC FMUSP medical records review regarding the hospitalization diagnosis, length of stay and procedures realized. We estimated HCW performance comparing the periods before and after the implementation of the Brazilian primary prophylaxis treatment for severe patients.
Results: From 246 followed at HC FMUSP (2008-2018), 73 patients were hospitalized in this period. They were diagnosed at the mean age of 5,7 years (range: 0 – 46,8 years).
Table 1- Patients hospitalized in 2008 and 2018, and ages.
| 2008 | 2018 | |
| Patients Hospitalized (number/year) | 13 | 6 |
| Age (years in avarage) min – max |
15 year (range: 0,8-52,9) |
22 year (range: 2,4-62,9) |
Number of patients hospitalized in 2008 and 2018, and the ages.
Table 2- Hospitalization and causes from HC FMUSP, in periods A and B
| 2008 – 2011 (A) | 2012 – 2018 (B) | |
| Hospitalizations/year (min-max) | 6,7 (3,8 – 9,5) | 3,2 (1 – 6,2) |
| Age | 15 year (average) (range: 0,8-52,9) |
22 year (average) (range: 2,4-62,9) |
| Main causes of Hospitalizations | 1- Factor infusion 2- Bruise or hemorrhage 3- Trauma or Traumatic brain injury 4- Upper digestive bleeding, 5- Hematuria |
1- Factor infusion (in pediatric patients) 2- Mild traumatic brain injury 3- Fractures and arthroplasty. |
Hospitalization/year, age and causes of the Hemophilic inpatients from Hemophilia Center of the Hematology Service of HC FMUSP, in period A (2008-2011) and B (2012-2018)
Conclusions: The registered dates of hospital admission at SUS varied: some patients went to other hospitals some were registered by the municipal or state managers.
Although some discrepancies there were 52% decrease in hospitalization, probably due to the implementation of the primary prophylaxis program in Hemophilia, since 2011.
The hospitalizations causes were similar to literature In period B most hospitalizations for factor administration (< 5 years), while parents were trained for home infusion. Brain injuries (< 8y) arthroplasties in older.
To cite this abstract in AMA style:
Guersoni AC, Villaça P, Rocha V, Trindade E, Luiz OD. Consistency Analysis and Data Validation Regarding Hospitalization among Hemophilic Patients from the Hemophilia Center of the Hematology Service of HC FMUSP – (2008-2018) [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/consistency-analysis-and-data-validation-regarding-hospitalization-among-hemophilic-patients-from-the-hemophilia-center-of-the-hematology-service-of-hc-fmusp-2008-2018/. Accessed August 15, 2022.« Back to ISTH 2021 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/consistency-analysis-and-data-validation-regarding-hospitalization-among-hemophilic-patients-from-the-hemophilia-center-of-the-hematology-service-of-hc-fmusp-2008-2018/