Background: D-Dimer levels are elevated in patients with acute myocardial infarction and signify disease severity. However, the association of structural markers of myocardial injury with D-Dimer levels is not well studied.

Aims: Aim of this study was to assess the correlation between elevated D- Dimer levels and cardiac enzymes (Troponin I) in patients with acute myocardial infarction.

Methods: A total of 301 patients with Acute Myocardial Infarction were included in the study during a period of one year, from August 2018 to August 2019. Our patient population consisted of 230 males and 71 females. Average age of our patients was 43.2 years (range 26.7-87.5 years).Serial standard 12-lead electrocardiography (ECG) was performed in each patient. D-dimer, and troponin I testing was done for all the patients. D- Dimer levels were performed on Cobas-6000 chemistry analyzer and Troponin I levels were performed by electrochemiluminescence method.

Results: Of the 301 patients studied, all patients had elevated D-Dimer with an average D-dimer levels of 817 ng/ml. A total of 257 patients had elevated Troponin I levels with an average of 159 ng/ml (Range 27-631 ng/ml). A strong correlation between D Dimer levels and Troponin I was noted in these patients.( p value=0.003).

Conclusions: Based on the results of this study, it is evident that the measurement of D-dimer level correlates with Troponin-T in patients with acute myocardial infarction.

« Back to ISTH 2020 Congress

ISTH Congress Abstracts - https://abstracts.isth.org/abstract/correlation-of-d-dimer-levels-with-troponin-i-in-patients-with-acute-myocardial-infarction/