Background: Covid 19 was first reported in the early of march 2020, increasingly rapidly and today reaching 1,386,556 cases. Meanwhile the worldwide cases reach 117,727,822 cases as reported at  9 of march 2021. Clotting plays a big role in mortality and morbidity of Covid-19 infection, Ddimer a fibrin degradation product was used as a marker of hypercoagulable state were studied among patients admitted in Murni Teguh Memorial Hospital (MTMH) between March 2020 until February 2021.

Aims: This study aims to study the relationship between the increase of Ddimer levels and the number of deaths among Covid  19 patients.  

Methods: This is a cross-sectional study to investigate the increase of Ddimer levels among the death cases in Covid 19 patients.

Results: A total of 981 covid 19  cases admitted at MTMH  with the number of deaths 156 cases (15.8%), The ddimer level was elevated in 80.7% death cases. There was no statistical difference within the survive and death cases. (p= 0.085). The mortality rate of the renal failure ongoing dialysis with covid 19 was 100 %  with ddimer level above 2 (cut off level 0.5). Prothrombin time and Activated partial thromboplastin time levels were elevated in  57 % of death cases and there was a statistical difference between the survival and death cases (p=0.035).

Conclusions: Ddimer levels were  elevated in 80.7 of death cases in Covid 19 patients, with 57 % cases elevated in prothrombin time and activated partial thromboplastin time.
 

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ISTH Congress Abstracts - https://abstracts.isth.org/abstract/ddimer-and-the-correlation-with-the-mortality-rate-in-covid-patients-a-single-centre-report-in-medan-indonesia/