Abstract Number: PB1134
Meeting: ISTH 2021 Congress
Background: The International Initiative on Thrombosis and Cancer (ITAC) has recently published updated evidence-based clinical practice guidelines (CPGs) for the management of venous thromboembolism (VTE) in patients with cancer. However, implementation of these CPGs in daily oncology practice appears as particularly challenging in these complex patients.
Aims: To describe the process development and contents of a clinical decision support tool to implement the ITAC-CPGs for the treatment and prophylaxis of VTE in patients with cancer.
Methods: We constructed a multilayer framework to translate the ITAC-CPGs into executable knowledge. We followed an iterative process of CPGs executive summary, algorithms elaboration, app development using the Objective-C and Java programming languages, and testing, with revision through each step, to support the design of 3 validated modules (prophylaxis of VTE; treatment of non-catheter-related VTE; treatment of catheter-related VTE).
Results: The resulting workable mobile app integrates a large amount of information and recommended processes into a single handheld tool. In 2021, the ITAC app is available in English, French, Spanish, Portuguese and Russian in any iOS (iTunes App Store) or Android (Google Play) devices for free. This ITAC app constitutes a practical, step-by-step guide for the prophylaxis and treatment of VTE in cancer patients, based on simple decision-tree algorithms. By answering a series of questions, health care users can quickly determine a recommended course of action for any given patient based on his clinical scenario.
Conclusions: By translating written ITAC-CPGs into timely and effective decision-making, the multi-language ITAC app shall allow physicians and other healthcare professionals to overcome cancer-associated management challenges worldwide.
To cite this abstract in AMA style:Farge D, Frere C, Connors JM, Ay C, Khorana AA, Munoz A, Brenner B, Kakkar A, Rafii H, Solymoss (in memoriam) S, Brilhante D, Monreal M, Bounameaux H, Pabinger I, Douketis J. Development of a Multi-language Mobile App to Implement the 2019 ITAC Clinical Practice Guidelines for the Treatment and Prophylaxis of Venous Thromboembolism in Cancer Patients [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/development-of-a-multi-language-mobile-app-to-implement-the-2019-itac-clinical-practice-guidelines-for-the-treatment-and-prophylaxis-of-venous-thromboembolism-in-cancer-patients/. Accessed July 1, 2022.
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