Abstract Number: PB0534
Meeting: ISTH 2021 Congress
Background: Overweight (BMI>25) is a serious issue in European countries. Physical activity is advised to control body weight and promote healthy lifestyle. People with hemophilia (PWH) active in sports are expected to report less overweight and obesity.
Aims: To assess the association between BMI, limitations in activities and sports participation in PWH.
Methods: Data was collected during the cross-sectional nationwide study ‘Haemophilia in the Netherlands’ (HiN6). HiN6 included questionnaires concerning body composition (height, weight) and sports participation (self-reported limitations ((Pediatric) Hemophilia Activities List (Ped)HAL)) and Modifiable Activities Questionnaire (MAQ)). Data were presented as median (interquartile range). Body weight was grouped as ‘normal weight’ or ‘overweight’ (adults: BMI>25, children: BMI over age specific limit). Groups were compared using Chi-square testing.
Results: BMI was available for 664 adults (median age: 51 (35-62)) and 130 children (age: 9 (5-13)). Most participants had hemophilia A (87%; 37% severe, 86% prophylaxis; non-severe: 4.8% prophylaxis). Median BMI in adults was 25.3 (23.1-27.9) and 16.7 (15.0-18.7) in children, indicating 52% of adults and 13% of children were overweight. Table 1 shows weight distribution in PWH and the GP. Patients with severe hemophilia (39%) reported less overweight than those with non-severe hemophilia (50%). Fewer PWH reported severe obesity (BMI >30) than in the GP in both adults (0.8% vs. 13.5%) and children (0% vs 2%). BMI was not associated with sports participation in adults (rho: -0.08) and children (rho: 0.09) or weekly sports exposure (rho=-0.02). Figure 1 shows the association between BMI and self-reported limitations in activities: BMI was associated with self-reported limitations in activities (p<0.01; see figure 1).
|Distribution of weight and overweight in Dutch persons with hemophilia and the general population|
|People with Hemophilia||General Population|
|Overall||Normal overweight||Overweight*||Normal overweight||Overweight*|
Conclusions: Distribution of BMI between PWH and GP was comparable. However, BMI was not associated with sports participation in Dutch PWH. Overweight PWH reported more limitations than those with healthy weight. This could be cause or consequence.
To cite this abstract in AMA style:Versloot O, van Balen E, Hassan S, Schols S, Leebeek F, Coppens M, Eikenboom J, Hooimeijer L, van Vulpen L, Smit C, Driessens M, van der Net J, Gouw S, Fischer K, HiN6 steering group . Dutch Overweight People with Hemophilia Report More Limitations in Activities, but No Association with Sports [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/dutch-overweight-people-with-hemophilia-report-more-limitations-in-activities-but-no-association-with-sports/. Accessed January 26, 2022.
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