Abstract Number: PB1023
Meeting: ISTH 2020 Congress
Theme: Hemophilia and Rare Bleeding Disorders » Hemophilia - Clinical
Background: The most clinical manifestation of haemophilia as a congenital bleeding disorder is the Intra-articular haemorrhage.
The regenerative methods such as intraarticular platelet-rich plasma may herald a new era for the treatment of young patients with Hemophilic Arthropathy.
Aims: This study aimed to evaluate the effectiveness of PRP treatment for the reduction of pain and improvement of physical function in hemophilic arthropathy patients.
Methods: Consecutive patients with hemophilic arthropathy included in a self-control open-label trial in Mofid Children’s Hospital, Tehran Iran. All participants received three injections of PRP 2 weeks apart. The seriate self-reported and objective clinical outcomes evaluated before and three months after therapy.
Results: A total of 11patients with 14 joints treated at our centre with hemophilic arthropathy received three injections of PRP at 2-weeks intervals. All patients evaluated with a visual analogue scale (VAS), Hemophilia joint health score(HJHS), range of motion(ROM), and the existence of bleeding events before and after the treatment. The patients 9 (81.8%) boys, 2 girls(18.2%) completed the study. The Mean age was 14.7 years old (9-19 years old). Statistically, significant improvements noted in all of the evaluated measures in all of the patients.
Conclusions: Platelet-rich plasma therapy is a reasonable and minimally invasive procedure in which the chondroregenerative properties could be beneficial.
To cite this abstract in AMA style:
Eshghi P, Malek F, Habibpanah B, Davoudabadifarahani H. Efficacy of Platelet-rich Plasma in the Treatment of Hemophilic Arthropathy [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/efficacy-of-platelet-rich-plasma-in-the-treatment-of-hemophilic-arthropathy/. Accessed March 21, 2024.« Back to ISTH 2020 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/efficacy-of-platelet-rich-plasma-in-the-treatment-of-hemophilic-arthropathy/