Background: Epidemiologic study of patients with thrombotic events referred to tertiary hospital in southern Iran.

Aims: We aimed to evaluate the occurrence of thrombotic events and related risk factors in a group of Iranian patients.

Methods: In this cross-sectional study, all patients (n=99) who were complicated by thrombotic events referred to the Hematology Research Center of Shiraz University of Medical Sciences were investigated from 2015 to 2017, in Shiraz, Southern Iran. Data were collected from their medical records by a designed data gathering form.

Results: The mean age of the occurrence of thrombosis was 50 ± 20 years (range: 4-89 years). From all thrombotic events 52.5% occurred in females. Venous thrombosis was more prevalent (61.6%) than arterial. Hypertension, diabetes mellitus and ischemic heart disease were the most associated disease with thrombosis. Most of the patients (79.8%) had no episodes of relapse and the occurrence of relapse had no significant relationship with thrombophilia and underlying disease. Acceptable response rate for warfarin therapy was achieved in 46.5% with 5 mg and 43.4% with 5-7.5 mg. Frequency of the associated diseases with thrombotic events is shown in figure1.

Conclusions: The most common risk factors for thrombotic disease in our study were atrial fibrillation and rheumatic heart disease. It is reasonable to recognize high risk patients for recurrence of venous thromboembolic and arterial events. Moreover, prophylaxis is necessary in high risk patients to reduce the complications and health-care cost.

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ISTH Congress Abstracts - https://abstracts.isth.org/abstract/epidemiologic-study-of-patients-with-thrombotic-events-referred-to-tertiary-hospital-in-southern-iran/