Abstract Number: PB1071
Meeting: ISTH 2021 Congress
Background: Warfarin therapy requires intense patient participation to achieve treatment goals and its promotion is challenging in healthcare settings.
Aims: To evaluate the effect of an educational intervention adapted for patients on warfarin with poor anticoagulation control at two anticoagulation clinics in Brazil.
Methods: This is a controlled clinical trial with participants recruited at two public hospitals in Belo Horizonte, Southeast Brazil. Inclusion criteria were age ≥18 anos, both sexes, AF diagnosis under warfarin therapy, outpatient follow-up for at least six months, poor quality of anticoagulation control. The intervention was based on Paulo Freire´s theory and comprised four meetings offered over a four-month period. Sociodemographic and clinical data, as well as adherence information, were collected from medical records and patient interviews. The primary outcome was the time in therapeutic range (TTR), and the secondary outcomes were patient knowledge on oral anticoagulation, and self-report adherence to warfarin therapy. These variables were measured in both groups in the pre- and post-intervention phases. TTR<60% was considered to classify poor anticoagulation control. Patient knowledge was assessed by using the Oral Anticoagulation Test (OAK Test). Trial registration: Registro Brasileiro de Ensaios Clínicos (ReBEC) RBR- 9cy6py; UTN U1111-1217-0151 (March, 2019).
Results: Overall, 168 participants were enrolled with 83 allocated to the intervention group and 85 to the control group. The mean age was 65±12.6 years with a predominance of women (56.6%). Most patients presented non-valvar AF (101; 60.1%) as indication for oral anticoagulation. There was no statistical difference between groups regarding TTR and adherence. The intervention was associated with an increase of three points in the knowledge score (p<0.001).
Conclusions: Our findings showed the contribution of an educational intervention to patient knowledge on warfarin therapy. Further studies are needed to investigate strategies to improve the quality of care provided to warfarin patients with poor anticoagulation control.
To cite this abstract in AMA style:
Costa JM, Marcolino MS, Praxedes MFS, Torres HC, Souza RP, Nascimento DV, Ferreira CB, Antunes NS, Viana RC, Araújo JA, Fernandes LA, Braga LdFM, Silva ACR, Barbosa HC, Ribeiro DD, Martins MAP. Evaluation of the Effect of Educational Intervention Adapted for Patients on Warfarin with Poor Anticoagulation Control: A Controlled Clinical Trial [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/evaluation-of-the-effect-of-educational-intervention-adapted-for-patients-on-warfarin-with-poor-anticoagulation-control-a-controlled-clinical-trial/. Accessed April 18, 2024.« Back to ISTH 2021 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/evaluation-of-the-effect-of-educational-intervention-adapted-for-patients-on-warfarin-with-poor-anticoagulation-control-a-controlled-clinical-trial/