Abstract Number: PB0758
Meeting: ISTH 2021 Congress
Theme: Role of Hemostatic System in Cancer, Inflammation and Immunity » Platelets and Cancer
Background: A prothrombotic state in oncologic patients represent a high risk problem, so evaluation of hemostasis is relevant for their monitoring. Thromboelastography (TEG) evaluates coagulation and fibrinolysis functionality and identifies altered phase that contributes to treatment decision.
Aims: The study aim is to evaluate hemostasis by TEG in patients with a diagnosis of neoplasia in a Peruvian oncology center.
Methods: A descriptive cross-sectional study was performed, with a review of two years (2017-2018) reports. TEG parameters were categorized into decreased, normal and increased according reference intervals. The software used was STATA.
Results: 360 reports were included, patients with antithrombotic therapy and double reports were excluded. Female cases reached 55%, being cérvix cancer the most frequent diagnosis with 11% (see Table 1). For TEG parameters, R(4-8 seconds) and K(1-4 minutes) were categorized normal above 70% of cases, while alpha angle (47°-74°), MA (55-73 mm) and CI (-3 to +3) showed mostly frequencias between normal and increased categories (see graphic 1).
Table 1.
años de edad) | sexo | total | Neoplasia por órgano afectado | total | |||||
masculino | mujer | norte | % | norte | % | ||||
norte | % | norte | % | ||||||
niños (0-11) |
4 | 2.5 | 11 | 5.5 | 15 | 4.2 | cuello uterino | 39 | 10,83 |
hígado | 26 | 7.22 | |||||||
adolescente (12-17) |
10 | 6.2 | 7 | 3,5 | 17 | 4,7 | ovario | 23 | 6,39 |
colon | 21 | 5.83 | |||||||
joven (18-29) |
17 | 10,6 | 8 | 4.0 | 25 | 6,9 | vesícula biliar | 20 | 5.56 |
pecho | 20 | 5.56 | |||||||
adulto (30-59) |
58 | 36 | 85 | 42,7 | 143 | 39,7 | gástrico | 19 | 5.28 |
adulto mayor (más 60) |
72 | 44,7 | 88 | 44,2 | 160 |
44,4 |
páncreas | 18 | 5 |
otros | 174 | 48,3 | |||||||
total | 161 | 100 | 199 | 100 | 360 | 100 | total | 360 | 100 |
Conclusions: Hemostatic evaluation by TEG in oncologic patients demostrated a hypercoagulable state due increased MA (related to platelets) in 48,9% of cases and alpha angle (clot formation velocity) in 42,5%.
To cite this abstract in AMA style:
Motta Rosada LF, Rodriguez Torres RM, Herrera Valverde NV. Hemostatic Evaluation by Thromboelastography in Patients from a Peruvian Oncologic Center [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/hemostatic-evaluation-by-thromboelastography-in-patients-from-a-peruvian-oncologic-center/. Accessed March 22, 2024.« Back to ISTH 2021 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/hemostatic-evaluation-by-thromboelastography-in-patients-from-a-peruvian-oncologic-center/