Abstract Number: PB1326
Meeting: ISTH 2022 Congress
Theme: Venous Thromboembolism » VTE Epidemiology
Background: Pregnancy is a well-known transient risk factor for venous thromboembolism (VTE).
Aims: This was the second nationwide study to examine the relationship between the increased proportion of patients of advanced maternal age and the incidence rate of pregnancy-associated VTE (PA-VTE) during the study period (2014–2018) compared with those in a previous study (2006‒2010).
Methods: Using the Korean Health Insurance Review and Assessment Service database, we retrospectively identified all PA-VTE events using both diagnostic and medication codes.
Results: Out of 124,228 VTE events, 510 (0.4%) cases of PA-VTE were identified in 499 women (median 34, range 20–49). The incidence rate of PA-VTE per 10,000 (PA-VTE/104d) in this second study (2.62) was 3.2 times higher than the rate in the first study (0.82). In the second study, the PA-VTE/104d of women in their 40s (5.46) was three times higher than that of women in their 20s (1.80) (relative risk [RR], 3.03; 95% CI, 2.04‒4.51; p < 0.01). The incidence rate in their 40s in second study was 2.3 times higher than that in their 40s in first study. Cases of PA-VTE/104d occurred more frequently in cases of multiparity than in those with nulliparity, in cesarean section compared with vaginal delivery, and in multiple compared with single pregnancies. Most cases of PA-VTE occurred in postpartum period (321/510, 62.9%). The PE was the frequent type of VTE in postpartum (231/321, 72%)
Conclusion(s): Advanced maternal age increases the risk of PA-VTE. Obstetricians need to be cautious about the risk of VTE, particularly during postpartum in women in their 40s.
To cite this abstract in AMA style:
Hwang H, Bang S, Lee J. Incidence of Pregnancy-associated Venous Thromboembolism: Second Nationwide Study [abstract]. https://abstracts.isth.org/abstract/incidence-of-pregnancy-associated-venous-thromboembolism-second-nationwide-study/. Accessed March 22, 2024.« Back to ISTH 2022 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/incidence-of-pregnancy-associated-venous-thromboembolism-second-nationwide-study/