Background: Behçet´s disease (BD) is a multisystemic inflammatory disease of unknown etiology that involves inflammatory processes in vessels of different calibers. Its clinical manifestations include cutaneous, oral, genital and ocular lesions, as well as neurological symptoms and vascular impairment, which is the main cause of death due to the risk of thrombosis.

Aims: Record case of a patient with BD, deep endometriosis and adenomyosis after using LNG-IUS for symptom control and lower risk of thromboembolic events.

Methods: The information was obtained by reviewing the medical record and discussed based on the review of the literature found in PubMed and Scielo sources.

Results: BD is a thrombophilic disease characterized by chronic systemic vasculitis that can involve both the venous system (88%) and the arterial system (12%). According to the 2015 World Health Organization eligibility criteria for the use of contraceptive methods in patients with a history of thrombosis, combined hormones are contraindicated due to the estrogenic component, being an option, hormonal methods containing only progesterone, such as LNG-IUS. In this specific case, it was also used to control the symptoms of deep endometriosis and adenomyosis.

Conclusions: The use of LNG-IUS proved to be an effective option in the control of symptoms related to deep endometriosis / adenomyosis in a patient at high risk of thrombosis, and further studies are needed to demonstrate this efficacy.

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ISTH Congress Abstracts - https://abstracts.isth.org/abstract/levonorgestrel-releasing-intrauterine-system-lng-ius-in-a-patient-with-deep-endometriosis-adenomyosis-and-behcets-disease-case-report/