Abstract Number: PB0869
Meeting: ISTH 2020 Congress
Background: Hemophilia treatment as prophylaxis requires frequent venous work. Port-a-cath (port) may be required to facilitate reliable venous access especially in young children. As a center, we have preferred less frequent injections for prophylaxis like Canadian approach. We did not use ITI programs due to reimburment reasons as well.
Aims: In this report, we evaluated our clinical experience with Ports in children with severe hemophilia A and vWD Type3.
Methods: Fifteen ports were placed in 9 boys with severe hemophilia A and 1 girl with vWD Type3 for last 30 years. The ages at the time of initial catheter placement ranged from 9 months to 10 years; Five were under age 3 (mean: 3.3 years). Two patients had high titer inhibitor. Indications for catheter placement were primary or secondary prophylaxis in patients who needed multiple infusions. We did not use heparin solutions and used only saline flash for preventing thrombosis.
Results: Subjects were admitted to hospital for a mean of 3.5±1.3 days for port-a-cath insertion. While no complications were experienced during insertion, only one patient developed post-operative hematoma at the port catheter site. Totaly 15 ports remained in place for 925 months (mean 65; range 2-156 months). In one inhibitor case (10%), port-a-cath was removed 2 months after due to catheter infection and sepsis. In another one case catheter was replaced 5 years after insertion due to thrombosis. In 3 cases, catheters were replaced due to deformation without any complication.
Conclusions: Generally, one third of patients had problems with thrombosis and infection. Other patients were happy with port during long-term prophylaxis. The lack of catheter-related infections may be due to less frequent device access, strict adherence to aseptic technique. Nowadays, we hope to proceed with SC agents with prophylaxis.
To cite this abstract in AMA style:Kavakli K, Balkan C, Erdener A, Karadaş N, Onen S, Yilmaz Karapinar D. Limited Port-A-Cath Need for Hemophilia Patients in the Past: Experience in a Single Center [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/limited-port-a-cath-need-for-hemophilia-patients-in-the-past-experience-in-a-single-center/. Accessed November 27, 2021.
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