ISTH Congress Abstracts

Official abstracts site for the ISTH Congress

MENU 
  • Home
  • Congress Archive
    • ISTH 2022 Congress
    • ISTH 2021 Congress
    • ISTH 2020 Congress
  • Resources
  • Search

Management of Hemostatic Balance in Elective Joint Replacement Surgery in Patients with Haemophilia

O.V. Badulescu1, P.D. Sirbu2, R. Tudor1, M.C. Vladeanu1, M. Ciocoiu1, I. Bararu Bojan1

1University of Medicine and Pharmacy “Grigore T. Popa”, Iaşi, Romania, 2University of Medicine and Pharmacy 'Grigore T. Popa', Iasi, Romania

Abstract Number: PB1019

Meeting: ISTH 2020 Congress

Theme: Hemophilia and Rare Bleeding Disorders » Hemophilia - Clinical

Background: Hemophilia is a genetic or acquired disease that leads to spontaneous and recurrent bleedings, which affect the joints and muscles, thus determining chronic damage to the cartilage which will lead to joint disease and hemophilic arthropathy. Even though hemophilic patients were initially thought to have a low incidence of atherothrombotic complications, it is now clear that atherothrombotic events occur.

Aims: This clinical study aims to underline the best manner of treating patients with elective joint replacement and hemophilia.

Methods: We analyzed five patients with hemophilia type A, aged between 35 and 62 years. Two of them had a severe form of hemophilia with factor VIII less than 1%, while the other three had a moderate form with factor VIII ranging between 1 and 5%. The five patients underwent total knee repair interventions and received substitution treatment with clotting factors but also prophylactic anticoagulant treatment.

Results: The postsurgical evolution of these patients was favorable, with similar hemostatic profile as the non-hemophilic patients. Moroctocog alfa is an efficient substitutive treatment that manages to normalize the hemostatic profile of patients.

Conclusions: Therefore, it is recommended to provide prophylactic antithrombotic therapy after the orthopedic interventions in hemophilic patients.

To cite this abstract in AMA style:

Badulescu OV, Sirbu PD, Tudor R, Vladeanu MC, Ciocoiu M, Bararu Bojan I. Management of Hemostatic Balance in Elective Joint Replacement Surgery in Patients with Haemophilia [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/management-of-hemostatic-balance-in-elective-joint-replacement-surgery-in-patients-with-haemophilia/. Accessed November 29, 2023.

« Back to ISTH 2020 Congress

ISTH Congress Abstracts - https://abstracts.isth.org/abstract/management-of-hemostatic-balance-in-elective-joint-replacement-surgery-in-patients-with-haemophilia/

Simple Search

Supported By:

Takeda logo

ISTH 2022 Congress site

Visit the official web site for the ISTH 2022 Virtual Congress »

  • Help & Support
  • About Us
  • Cookies & Privacy
  • Wiley Job Network
  • Terms & Conditions
  • Advertisers & Agents
Copyright © 2023 John Wiley & Sons, Inc. All Rights Reserved.
Wiley