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Management of Thrombocytopenia in Obstetric Patients: A Retrospective Teaching Hospital Experience

M. Moreno Carbonell, A. Gómez Martínez, J.M. Calvo Villas, N. Fernández Mosteirín, S. Martín-Consuegra Ramos, C.F. Hernández Mata, E. González Gómez, M. Civeira Marín, A.J. García Ortego, S.F. Pinzón Mariño

Hospital Universitario Miguel Servet, Zaragoza, Spain

Abstract Number: PB2569

Meeting: ISTH 2020 Congress

Theme: Women Health » Pregnancy and Pregnancy Complications

Background: Several causes of thrombocytopenia during pregnancy have been described, being gestational thrombocytopenia (GT) the most common. Monitoring platelet counts during pregnancy is essential to improve obstetric management face to the delivery.

Aims: Analyze the experience in the management of women with thrombocytopenia during pregnancy in our Hematology Unit.

Methods: We included women with thrombocytopenia during pregnancy diagnosed in our Unit from June 2018- January 2020. Sociodemographic, clinical and analytical variables of the pregnant women have been described.

Results: 23 women with thrombocytopenia during pregnancy were referred to manage in our Hematology Unit; a diagnosis of GT was established in 16 patients. Women were referred to our Unit at 37 week of gestation, median age was 37.5 years (32-43). Media platelet count at diagnosis was 98.5 x 109/L (67-115), platelet count postdelivery 144.5 x 109/L (80-267) and media platelet number before pregnant was 162.5 x 109/L (115-235).
31.25% women underwent a cesarean delivery and up to 12.5% an instrumental delivery. Epidural anesthesia was administered in 8 pregnant women. 2 patients presented obstetric complications (obstetric haemorrhage), requiring platelet transfusion. Only 3 patients had a pathological puerperium (because of anemia).

Conclusions: Multidisciplinary care including differential diagnosis of thrombocytopenia, evaluation of haemorragic risk of the delivery and proper treatment is required in the management of pregnant women with thrombocytopenia during pregnancy.

To cite this abstract in AMA style:

Moreno Carbonell M, Gómez Martínez A, Calvo Villas JM, Fernández Mosteirín N, Martín-Consuegra Ramos S, Hernández Mata CF, González Gómez E, Civeira Marín M, García Ortego AJ, Pinzón Mariño SF. Management of Thrombocytopenia in Obstetric Patients: A Retrospective Teaching Hospital Experience [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/management-of-thrombocytopenia-in-obstetric-patients-a-retrospective-teaching-hospital-experience/. Accessed May 19, 2022.

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