Abstract Number: PB0585
Meeting: ISTH 2021 Congress
Background: Hemophilia carriers are prone to suffer from mental health problems, but there are still very limited data of mental health status of hemophilia carriers in China.
Aims: This study was to investigate mental health status of hemophilia carriers in China.
Methods: Hemophilia carriers were asked to complete the Symptom Check-list 90 (SCL-90, China/Mandarin version) from April 2018 to April 2020. Each item is rated on a five-point scale, with 1–5 representing the severity of the symptoms from “none” to “severe”. When the score of an item is equal or greater than 2, this item is considered a positive item. If the total score exceeds 160, number of positive items exceeds 43, or any factor score exceeds 2, it is considered the participants have psychological symptoms. The measurement data were expressed as mean (± standard deviation) and the t test was performed for comparison between groups which indicated hemophilia carriers and Chinese population norms.
Results: A total of 71 valid questionnaires were collected. The total mean score, the global severity index and the number of positive items of SCL-90 for surveyed hemophilia carriers were 173.03 (± 60.80), 1.92 (± 0.68), and 46.04 (± 22.55), respectively, all of which were markedly higher than those in the Chinese population norms (P < 0.001). 73.2% of the respondents (n = 52) were identified with psychological symptoms. The pooled estimates of all the nine factors, including somatization, obsession-compulsion, interpersonal-sensitivity, depression, anxiety, hostility, phobic anxiety, and paranoid ideation among hemophilia carriers, were significantly higher than those in the general population (P < 0.001). Obsessive-compulsion and depression were most common and severe factors, and their rates were 63.4% and 54.9%, respectively.
Conclusions: The situation of psychological health of hemophilia carriers in China is worrying, and it is urgent to take some effective measures to improve their mental health.
To cite this abstract in AMA style:Cui D, Hu Q. Mental Health Status of Hemophilia Carriers in China [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/mental-health-status-of-hemophilia-carriers-in-china/. Accessed December 11, 2023.
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