Abstract Number: PB2314
Meeting: ISTH 2020 Congress
Background: DVT is a frequent cause or morbidity and mortality, and multiple factors are involved in its etiopathogenesis. In Vall d’Hebron University Hospital, we have stablished an ordered multidisciplinary system to follow our DVT patients and to try to ensure an appropriate correct approach of the disease.
Aims: To identify our DVT population demographics and characteristics of the disease, as well as mid-term complications within our DVT unit.
Methods: Observational and prospective study between January 2017-December 2018. Two years of follow up.
Results: We included 295 patients with DVT, 55.9% were men, the average age was 66.8 years old, 84.4% were in lower limbs and 17% associated pulmonary embolism (PE). We tested 34.6% for thrombophilia and only 13.2% were positive. 42.2% were idiopathic DVTs, most of them without personal or familiar history of DVT, and only 20% of positive thrombophilia test. All patients started LMWH treatment for 7-10 days but 50.2% switched to VKA and 18.3% to DOACs, 0.7% changed to Fondaparinux. After 3-6 months of treatment, 33.22% resolved and 41.4% had residual/chronic DVT. After 2 years of follow up, we found 16.6% of post thrombotic syndrome (PS) and 1.35% of bleeding complications. We had 4 PEs, 1 splenic thrombosis, and 1 recurrent DVT after stopping treatment. One patient presented extension of DVT during LMWH treatment. We identified 9 patients with cancer, 6 of them diagnosed during the extended study of the idiopathic DVT.
Conclusions: We found an important percentage of idiopathic DVT with most negative thrombophilia tests, which suggests a lack of biological/genetic scores that reach a good predictive role in recurrent DVT. Hidden neoplasms should be investigated, as DVT can be the first sign. After 2 years of follow up, we found a low rate of PS (40% in the literature), 2% of recurrent thrombosis and only 1.35% of severe hemorrhage as complications.
To cite this abstract in AMA style:Suito Alcántara MA, Benitez Hidalgo O, Cabirta Touzón A, Martínez García MF, Catalá Bardisa E, Paredes Mariñas E, Robayo Buitrago GI, Díaz Bernal JJ, Cambra López Y, Soria Chico R, Gironella Mesa M. Multidisciplinary Approach of Deep Venous Thrombosis (DVT) in Vall d’Hebron University Hospital: Two Years’ Experience [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/multidisciplinary-approach-of-deep-venous-thrombosis-dvt-in-vall-dhebron-university-hospital-two-years-experience/. Accessed May 16, 2022.
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