Abstract Number: PB0274
Meeting: ISTH 2021 Congress
Theme: COVID and Coagulation » COVID and Coagulation, Clinical
Background: Coagulopathy is one of the serious manifestations of COVID-19, however this infection is also related to an increased incidence of VTE. VTE prevention in these patients was not standardized, especially at the beginning of the pandemic.
Aims: To evaluate the VTE prevention strategies in patients with COVID-19 in Uruguay.
Methods: Descriptive observational study, based on an online survey, whose target population includes physicians from Uruguay who assisted COVID-19 patients. It was available online from 4/9 to 5/10/2020. However, given the increase in cases in Uruguay, the survey was relaunched in March 2021.
Results: 42 physicians completed the survey. 29 assisted patients with moderate and 17 assisted patients with severe COVID-19 (4 assisted both groups).
Moderate COVID (required hospitalization)
23 used pharmacological and 2 used mechanical thromboprophylaxis. 12 used a LMWH dose of 40 mg/day, 7 used 1 mg/kg/day, 4 used 60 mg/day. 13 had doubts about whether to indicate thromboprophylaxis.10 requested D-dimers and in 9 cases they were augmented.
Severe COVID (required admission to ICU)
All used pharmacological thromboprophylaxis. 5 used a LMWH dose of 1 mg/kg every 12 hours, 4 used 40 mg/day, 4 used 1 mg/kg/day, 2 used 60 mg/day and 1 used 1.5 mg/kg/day.
16 requested D dimers, in all cases they were increased.
Regarding the preliminary results of the second phase. 17 doctors completed the survey, all of them cared for patients with moderate COVID. 14 used pharmacological thromboprophylaxis, 12 with doses of LMWH of 40 mg/day and 2 with doses of 1 mg/kg/day. 5 had doubts whether to indicate thromboprophylaxis. 11 cared for patients with severe COVID, 10 used pharmacological thromboprophylaxis (5 used LMWH 1 mg/kg every 12 hours, 2 used 1 mg/kg/day and 3 used 40 mg/day).
Conclusions: A heterogeneous approach to VTE prevention has been observed among physicians who cared for COVID-19 patients.
To cite this abstract in AMA style:
Pizzarossa A, Spangenberg MN, Munka F, Borges B, Sosa M, Passarella F, Aguirre M, Falero E, Guillermo C. National Survey about Management of Venous Thromboembolism (VTE) Prevention in COVID-19 Patients in Uruguay [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/national-survey-about-management-of-venous-thromboembolism-vte-prevention-in-covid-19-patients-in-uruguay/. Accessed December 1, 2022.« Back to ISTH 2021 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/national-survey-about-management-of-venous-thromboembolism-vte-prevention-in-covid-19-patients-in-uruguay/