Abstract Number: PB2303
Meeting: ISTH 2020 Congress
Background: Venous thromboembolic disease (VTED) can reveal systemic vasculitides (S V) or appear during their evolution.
Aims: The aim of our study was to determine the particularities of venous thromboembolic events in patients with SV.
Methods: We conducted a retrospective study of in patients hospitalized for VTED records in the internal medicine department over a 23-year period (1995-2018).
Results: Among 1553 cases of venous thromboembolism , 107 patients (6.8%) have SV including 75%men and 25% women (sex ratio F / H at 0.3).The average age at the time the diagnosis of thrombosis was 44 years. VTED was indicative of the underlying vascularity in 71% of the cases, it occurred during monitoring of the vascularity involved in the rest of cases. Thrombophlebitis was localized : in the lower limbs in 62% cases, pulmonary embolism was found in 11% of cases, portal thrombosis, of the superior vena cava and jugular thrombosis were found in 6% each, cerebral thrombosis in 4%, and in the upper limb in 2%. the vasculitides found were : Behcet’s disease(n= 102), granulomatosis with Polyangiitis (n=1) , microscopic polyangiitis (n=1) , Cryoglobulinemic Vasculitis (n=1) and indeterminate vasculitis(n=2) . Anticoagulant therapy was indicated in all patients for an average duration of 18 months. The corticosteroid therapy was indicated in 81% of cases and treatment immunosuppressant in 56% cases. Thrombophlebitis was recurrent in 9 cases under anticoagulant treatment.
Conclusions: There is more and more evidence of links between the presence of a systemic vascularity and the occurrence thromboembolic events. A rigorous etiological investigation before a first episode of venous thrombosis can allow an early positive diagnosis of the vasculitis in question. In our series, behcet´s disease was the most common cause which joins literature data.
To cite this abstract in AMA style:Ben Achour T, Said F, Naceur I, Baccouche H, Lamloum M, Khanfir M, Houman MH, Ben Romdhane N. Particularities of Venous Thromboembolism in Systemic Vasculitides [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/particularities-of-venous-thromboembolism-in-systemic-vasculitides/. Accessed November 29, 2023.
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