Abstract Number: PB2216
Meeting: ISTH 2020 Congress
Background: Postthrombotic syndrome (PTS) is a chronic but preventable complication after deep vein thrombosis (DVT). It can seriously affect patients quality of life and has a major impact on health care costs. PTS is a consequence of inadequate venous circulation due to chronic venous obstruction, valvular insufficiency and increased exposure to inflammatory mediators. Recent technical innovations now make it possible to carry out recanalization of acute venous obstructions with percutaneous transluminal angioplasty and stenting and more recently but less studied in chronic obstructions
Aims: To assess immediate and at 6 months efficacy and safety of recanalization of chronic venous obstructions.
Methods: All consecutive patients treated by recanalization of a chronic venous obstruction with PTS between 01/01/2015 and 01/12/2019 in our center were included and files retrospectively reviewed. Results are mean±SD.
Results: There was 63 (71%) women among the 89 patients included. Age was 43±14,1 years and body mass index 26±2,5 kg/m². All patients had had DVT at least 3 months previously and 68 (76%) still presented iliofemoral occlusive sequelae, despite well-conducted anticoagulation. Villalta score was 9±4,1, and 8 (9%) had venous ulcer.
Recanalization succeeded in 88 patients and 84 received at least 1 stent per procedure. 64 (73%) patients received direct oral anticoagulant and 24 VKA after recanalization. On top 78 patients received also anti-platelet therapy.
48 patients had the 6 months follow-up. Primary patency rate was 85%, Villalta score was 3.2±3.8. Ulcer healed in 1 patient, and reduced in size in 2 patients.
We retrieved 3 minor bleedings immediately after recanalization, but no major bleeding and no death at 1 and 6 months.
Conclusions: Recanalization of chronic venous obstruction appears to be an interesting therapeutic option in PTS leading to symptoms reduction without any major complication in a single-center large cohort.
To cite this abstract in AMA style:Khider L, Del Giudice C, Goudot G, Gobert C, Galloula A, Pernot M, Sapoval M, Messas E, Mirault T. Patency and Clinical Outcomes of Venous Recanalization in the Treatment of Postthrombotic Syndrome [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/patency-and-clinical-outcomes-of-venous-recanalization-in-the-treatment-of-postthrombotic-syndrome/. Accessed January 21, 2022.
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