Abstract Number: PB2549
Meeting: ISTH 2020 Congress
Background: Incidence of post partum hemorrhage (PPH), a leading cause of maternal morbidity and mortality, is increasing worldwide. Social and economic implications of this complication are significant. Data from the developing countries, where access to health care can be challenging, is scarce.
Aims: To investigate the prevalence, management and outcomes of PPH in Latin American countries.
Methods: A comprehensive overview was performed to assess: a) prevalence of PPH, defined as blood loss > 500 mL, and prevalence of severe PPH (blood loss >1000 mL). b) management: use of uterotonic agents, and tranexamic acid and transfusion requirements. c) outcomes: mortality and hysterectomy.
Data source: major electronic databases and hand-searching of abstracts presented at scientific meetings (Hematology, Obstetrics and Gynecology, and Intensive Care Medicine), and reference lists checking of the retrieved articles. Data abstraction was performed following a predetermined data abstraction form.
Results: We identified 118 potentially eligible publications. Only one systematic review (SR) fulfilled our inclusion criteria (Calvert C et al. PLoS ONE 2012; 7: e41114). The SR quality, using AMSTAR-2 tool, resulted in low quality (lack of detailed description of the primary studies and of the risk of bias). Eleven studies from Latin American and Caribbean region were included in the SR (23.129 women). The estimated prevalence of PPH is shown in Table 1. Regarding management of delivery: active management was reported in 4 studies (36 %); no information about transfusions or use of tranexamic acid was provided. There was no data about mortality and hysterectomy.
Conclusions: PPH is a prevalent complication in Latin America. However, high quality SR evaluating the prevalence, causes and management of post-partum hemorrhage in Latin America are warranted.
|Prevalence of blood loss per 100 women giving birth||Prevalence of blood loss per 100 women giving birth based only on studies which used objective method of blood loss measurement|
|PPH||8.2 (6.1-10.4)||11.9 (6.0-19.5)|
|Severe PPH||3.3 (1.8-5.2)||4.1 (1.9-7.0)|
[Prevalence of PPH in Latin America]
To cite this abstract in AMA style:Casais P, Lavena Marzio A, Ocampo C, Salgado P, Squassi A, Izcovich A. Prevalence and Management of Post Partum Hemorrhage in Latin America: An Overview of Systematic Reviews [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/prevalence-and-management-of-post-partum-hemorrhage-in-latin-america-an-overview-of-systematic-reviews/. Accessed December 8, 2021.
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