Abstract Number: PB2218
Meeting: ISTH 2020 Congress
Background: Post-thrombotic syndrome is a debilitating illness with significant impact on quality of life. Iliac vein stenting to treat deep venous obstruction in post-thrombotic syndrome is growing in popularity.
– To measure change in venous disease-specific quality of life after iliac vein stenting for chronic deep venous obstruction.
– To identify factors associated with improvement post-stenting.
Methods: We performed a retrospective analysis of VEINES-QoL/Sym questionnaires completed at baseline and follow-up after iliac vein stenting (6-36 months). Item responses were re-coded using the intrinsic method to calculate a score out of 100. Additional patient data were obtained from electronic records.
Results: We identified 188 patients who had completed one or more VEINES-QoL/Sym at baseline or follow up (6- 12- 24- 36 months). Median follow-up was 12 months, 127 (68%) were female and 149 (79%) were treated for post thrombotic disease. Sixty patients (31%) required re-intervention and 6 (3%) had occluded stents that could not be recanalized.
Mean VEINES-QoL/Sym score at baseline was 36.75 [32.37-41.12]. Significant improvement was observed post-operatively and sustained at 6-,12-,24- and 36-month follow up (61.47 [56.64-66.31], 59.03 [53.69-64.37], 57.35, [51.13-63.58] 59.36 [50.55-68.16] p=< 0.05). Median Villalta score decreased from 14 at baseline to 8.5 at 6 months, 7.5 at 12 months, 7 at 24 months and 6 at 36 months follow-up (p=< 0.05).
A subgroup analysis of patients with patent stents found that those with ≤ 35% in-stent stenosis on duplex ultrasound at follow-up had improved VEINES-QoL/Sym scores compared to patients with >35% stenosis (62.04 vs 51.51, p=< 0.05).
Conclusions: Venous-disease specific quality of life improved significantly after deep venous stenting, and this was sustained at 6- 12 -24- and 36 months follow-up.
To cite this abstract in AMA style:Morris R, Pouncey A, Quintana B, Khan T, Gwozdz A, Smith A, Saha P, Black S. Quality of Life Outcomes after Iliac Vein Stenting for Chronic Deep Venous Obstruction: A Tertiary Centre Experience Using the VEINES-QoL/Sym [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/quality-of-life-outcomes-after-iliac-vein-stenting-for-chronic-deep-venous-obstruction-a-tertiary-centre-experience-using-the-veines-qol-sym/. Accessed November 27, 2021.
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