Abstract Number: PB2217
Meeting: ISTH 2020 Congress
Background: Post-thrombotic syndrome (PTS) develops approximately 20-60% of patients after DVT and affects the overall QOL negatively, reducing working time because physical limitations and emotional stress due to fear of recurrence. DVT associated with hospitalization was the leading cause of disability-adjusted-life-years (DALYs) lost in low and middle income countries.
Aims: To evaluate QOL of patients with DVT treated in Hemostasis and Thrombosis Unit (UHYT), in Hospital de Clinicas (HC), Uruguay.
Methods: We performed a transversal cohort study in patients attending UHYT, between 2019 -2020. We applied VEINES score surveys in patients over 18 years and took epidemiologic data from medical history. Individual consent and approval from the ethics committee was taken.
Results: 60 patients with DVT were surveyed. Median age: 58 years. Men vs. women, 0.9 vs.1.
Thrombotic events: 73% DVT alone, 27% pulmonary embolism (PE) associated. DVT: 60% left limb, 40% right limb. Recurrence was seen in 45%. Warfarin was used in 60% of cases. 73% developed PTS. Symptoms are shown in figure 1.
Patients with PTS showed higher VEINES/QOL scores. We found an association between women and higher VEINES/QOL scores and in working patients (table 1). Symptoms got worse during activity. Social limitations were both sitting and standing activities. Localization of DVT, anticoagulant therapy, and recurrence did not show association with a worse QOL. 95% of patients who changed anticoagulation to DOACs showed an improvement in their QOL.
Conclusions: The incidence of PTS in our population was higher than reported in the international bibliography. As we expected, PTS has a negative impact on the QOL of patients, showing the need to empower patients in the prevention of the primary event of DVT, focusing mainly on thromboprophylaxis with worldwide awareness campaigns.
[Table 1 – Results]
To cite this abstract in AMA style:Matosas MV, Boada M, Guillermo C. Quality of Life (QOL) Assessment Using VEINES/QOL Score for Deep Vein Thrombosis (DVT) Patients in Uruguay [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/quality-of-life-qol-assessment-using-veines-qol-score-for-deep-vein-thrombosis-dvt-patients-in-uruguay/. Accessed November 27, 2021.
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