Abstract Number: PB2371
Meeting: ISTH 2020 Congress
Theme: Venous Thromboembolism and Cardioembolism » VTE Prophylaxis
Background: The risk factors associated with developing thrombosis, e.g. immobility or active malignancy are more prevalent in hospitalized patients. These patients need to be treated with adequate thrombosis prophylaxis (TP) during hospitalisation.
Aims: To determine, in a real life hospitalized population setting, the proportion of patients without TP and the proportion of these patients at high risk to develop thrombosis. Furthermore, the feasibility and effectiveness of manually reviewing and intervening in ‘high-risk’ patients by an antithrombotic stewardship program (ASP) was studied.
Methods: Prospectively, over a period of 3 months, all patients who were hospitalized for more than 72 hours and did not receive TP (heparins, DOAC nor VKA) enrolled in this observational study. The risk of thrombosis was assessed daily, using the PADUA scoring system. Patients with a PADUA score >4 were assigned as being at high risk of developing thrombosis. The characteristics of these patients were studied. Furthermore, these patients were manually reviewed by one nurse and discussed in the ASP to assess if interventions were needed.
Results: From February to May 2019, there were 586 consecutive patients enrolled. Of these, 389 (66%) patients were scored as low risk of thrombosis, while 197 (44%) patients were considered as at high risk. In this period, the ASP was able to review 60 (30%) of the high risk patients. Intervention by means of starting TP was carried out in 19 (32%) out of the 60 reviewed patients.
Conclusions: Our study shows that still a high number of patients at high risk of thrombosis do not receive appropriate TP during hospitalisation. However, manually reviewing these high risk patients is time consuming as only 30% of high risk patients could be reviewed by the ASP.
To cite this abstract in AMA style:
Taskopru M, Slijkhuis M, van Wissen S, Khorsand N. Real Life Experience of an Antithrombotic Stewardship Program for Thrombosis Prophylaxis during Hospitalisation in a Large Teaching Hospital [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/real-life-experience-of-an-antithrombotic-stewardship-program-for-thrombosis-prophylaxis-during-hospitalisation-in-a-large-teaching-hospital/. Accessed October 1, 2023.« Back to ISTH 2020 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/real-life-experience-of-an-antithrombotic-stewardship-program-for-thrombosis-prophylaxis-during-hospitalisation-in-a-large-teaching-hospital/