Abstract Number: PB1204
Meeting: ISTH 2021 Congress
Background: Venous thromboembolism is accompanied with superficial thrombophlebitis in 25% of patients. Lethality in 3-6 months after deep vein thrombosis, according to different authors, is 7-15%. The role of preoperative risk factors for venous thromboembolism in endoscopic urological interventions have to be analized.
Aims: To examine the clinical, gender and coagulologic parameters of preoperating risk for venous thromboembolic complications factors before endoscopic urological interventions.
Methods: 1918 patients were examined, including 414 patients with venous thromboembolic postoperative complications (223 male, 191 female, average age 48.55 ± 13.77 years). Cumulative incidence (CI), cumulative incidence (UI) reduction, relative risk (RR) and odds ratio (OR) were analyzed.
Results: After prolonged prospective observation among 1918 patients in preoperating period it was set, that preceding chronic venous insufficiency could be the main basic risk factor of venous thrombosis during surgical interventions (р<0,05). It was proven the linear dependence between the class of chronic venous insufficiency and incident of peripheral thrombotic complications (р<0,05), with the highest risk for C3 and C4 classes (р<0,05).
It was estimated that women sex (р<0,05) reliably promotes the risk of venous thromboembolism with valid relative risk(1,53 [1,11-2,12]) and odds ratio (1,59 [1,13-2,27]) before surgical intervetions.
It was set that coagulogram indexes as the level of fibrinogen, prothrombin time and activated partial thromboplastine time should be analized in pre-operating period, but could not be the reliable markers of venous thromboembolism incidence before surgical intervetions (р>0,05).
Conclusions: Preexisting chronic venous insufficiency is the main risk factor for venous thromboembolism in urological interventions (p<0.05) with significant effect of C3-C4 (p<0.05). In female (p<0.05) was set significantly increases risk of venous thromboembolism after endoscopic urological interventions.
To cite this abstract in AMA style:Shorikova D, Shorikov E, Shorikov P. Risk Factors of Venous Thromboembolism at Patients with Endoscopic Urological Interventions [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 1). https://abstracts.isth.org/abstract/risk-factors-of-venous-thromboembolism-at-patients-with-endoscopic-urological-interventions/. Accessed September 23, 2021.
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