Abstract Number: PO159
Meeting: ISTH 2021 Congress
Theme: Platelet Disorders, von Willebrand Disease and Thrombotic Microangiopathies » Platelet Function Disorders, Acquired
Background: We report a rare case of unrepaired Tetralogy_Pantalogy of Fallot (TOF_POF) in a 20 years old girl, who presented with cyanotic finger tops appearance, ongoing thrombolytic processes and remarkable thrombocytopenia (1,2), heart ventricular septal defect (VSD), and might atrial septal defect (ASD), anxiety, sleep disorders, nightmares, and limited social life. Thrombocytopenia in cyanotic heart disease patients, although well known, is not adequately understood. These kind of TOF/POF patients are suffering of cyanotic blue blood circulation with erythrocytosis.
Aims: The aim was to prevent chronic thrombocytopenia which might be result of chronic compensation process selected by brain-heart axis to prevent premature thrombotic processes.
Methods: Owing to her growth retardation, unknown infections, poor cardiopulmonary status, the patient did not undergo surgery, and she only got medications and treatments with only symptomatic supportive therapy. We used novel developed technologies so called SONAPS to prevent further Erythrocytosis simultaneously inhibit Thrombocytopenia, without any platelet concentrates transfusion.
Results: Using the combination of detection by the Novel developed inhouse technology so-called SONAPS, Hematologic – and auricular medicine approaches, we succeeded to affect her ongoing thrombolytic processes, erythrocytosis, decreased her heart arrhythmic aspects, increased oxygenation of whole body, while she claimed that somehow cyanotic aspects of her skin and fingers appearance were decreased, after 24 hours. All clinical results were checked up again with new clinical and basic research testing i.e. clinical feature of fatigue, tachycardia, and ECG testing. The exact mechanism of these phenomenal reconciliation need more investigation.
Conclusions: Our inhouse developed approaches saved life of a patient with cyanotic TOF_POF disorders, who suffered from critical thrombocytopenia and erythrocytosis. Our approached novel system is working. We are looking for collaborations to carry out our model system, globally.
To cite this abstract in AMA style:
Badlou B, HN. Tetralogy of Fallot with Thrombolytic Ongoing Processes: A Case Report [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 2). https://abstracts.isth.org/abstract/tetralogy-of-fallot-with-thrombolytic-ongoing-processes-a-case-report/. Accessed November 29, 2023.« Back to ISTH 2021 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/tetralogy-of-fallot-with-thrombolytic-ongoing-processes-a-case-report/