Abstract Number: PB2331
Meeting: ISTH 2020 Congress
Theme: Venous Thromboembolism and Cardioembolism » VTE Epidemiology
Background: Superficial vein thrombosis (SVT) shares many common features with deep vein thrombosis (DVT) but epidemiological data about longer follow-up of SVT patients are scarce.
Aims: The aim of our study was to evaluate the characteristics of SVT patients, complications during follow-up and their potential predictors.
Methods: We performed a retrospective analysis of prospectively collected data from consecutive patients with isolated SVT of the legs who had been followed in thrombosis clinic. All provided an informed consent. We evaluated demographic, clinical and laboratory characteristics; thrombotic events or death during follow-up. For statistics we used T-test, Fisher´s exact test, Wilcoxon test and a logistic regression.
Results: We included 127 patients (mean age 57.6±14.5 years; 65.4% females), most (89%) with varicose vein SVT. The personal/family history of SVT was positive in 44.9%/33.9%; that of DVT/pulmonary embolism (PE) in 35.4%/29.9%. Thrombophilia was present in 36.2%. All the index events had been treated with anticoagulation, in very variable schemes. Follow-up duration was in a wide range (3-174 months, median 39 months). SVT recurred in 49 patients, in 22 repeatedly (up to 6 times). The interval to the first recurrence was 1-110, median 16 months. Only the history of previous SVT was significantly associated with recurrence during follow-up in a multivariate analysis (hazard ratio 1.69; P=0.027). DVT/PE occurred in 21 patients (3-124 months after the index SVT, median 18 months), in two patients repeatedly, none was fatal. No significant predictor was found for DVT/PE during follow-up. Six patients died (6-105 months after SVT).
Conclusions: In 127 patients with an isolated SVT of the legs, there was a high rate of recurrent thrombotic events during follow-up – mainly SVTs and, to a lesser extent, also DVT/PE. The history of previous SVT was the only significant predictor of further SVT recurrence. Our study underlines the need for well-designed epidemiologic research of SVT.
To cite this abstract in AMA style:
Hirmerová J, Seidlerova J, Subrt I, Hajsmanova Z. The Characteristics of Patients with Isolated Superficial Vein Thrombosis of the Legs, their Follow-up and Outcomes [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/the-characteristics-of-patients-with-isolated-superficial-vein-thrombosis-of-the-legs-their-follow-up-and-outcomes/. Accessed October 2, 2023.« Back to ISTH 2020 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/the-characteristics-of-patients-with-isolated-superficial-vein-thrombosis-of-the-legs-their-follow-up-and-outcomes/