Background: Prevention of venous thromboembolism (VTE) is important in undergoing major orthopedic surgery. It is not well-known how the physicians are adhering to the guidelines for thromboprophylaxis in real life practice.

Aims: This study aims to assess adherence rate to the thromboprophylaxis guideline affects the incidence of VTE.

Methods: This retrospective study using medical chart review the admitted patients underwent THA, TKA or HFS from March 2009 through February 2011. Compliance was defined adherence of orthopedic surgeons for chemical prophylaxis or mechanical prophylaxis. We assessed the adherence rate of thromboprophylaxis guideline, as well as analyzed incidence of VTE, major bleeding and all cause mortality in major orthopedic surgery within 3 months.

Results: The study population was total 391 patients (THA 80, TKA 95, and HFS 216 patients). The chemical compliance rate was 56% before surgery, 67% after surgery in total patients. The mechanical compliance rate was 100%. VTE occurred in 8 patients (8/391, 2.0%). Eight patients with pulmonary embolism (1/391, 0.26%), and 1 patient was pulmonary embolism with deep vein thrombosis (8/391, 2%). Major bleeding did not occur. The all-cause mortality was 3.6%(14/391)(THA 2.4%, TKA 1.1%, and HFS 5.1%). VTE related death was in one patient (1/391, 0.26%).

Conclusions: In this study, incidence of VTE in major orthopedic surgery within 3 months was similar with outcome of previous studies when preoperative and postoperative adherence rate of chemical prophylaxis was 56%, 67%, respectively.

« Back to ISTH 2020 Congress

ISTH Congress Abstracts - https://abstracts.isth.org/abstract/the-incidence-of-venous-thromboembolism-along-with-adherence-to-guideline-in-major-orthopedic-surgery/