Abstract Number: PB0117
Meeting: ISTH 2020 Congress
Background: Peripheral artery disease (PAD) and heart failure (HF) share the same risk factors and pathophysiological process. Patients with PAD have 2-fold higher risk of develop HF and the prevalence of PAD in these patients varies from 12-19%. However, most of these data are based on the prevalence of symptoms suggestive for PAD with scarce evidence from diagnostic specific tests.
Aims: To describe the prevalence of PAD diagnosed with ankle-brachial index (ABI) in hospitalized patients with acute HF and to evaluate the prevalence of symptomatic PAD assessed with the “San Diego Claudication Questionnaire” (SDCQ).
Methods: We conducted a multicentre prospective study in 5 Italian Internal Medicine Units. Hospitalized patients with acute HF were evaluated with the ABI test and the SDCQ. According to the International Guidelines, PAD was confirmed when ABI was ≤ 0.9. Patients with ABI >1.4 were excluded from the analysis. We also collected information about cardiovascular risk factors, comorbidities, concomitant medications and the last transthoracic echocardiogram. For every patient enrolled informed consent was obtained and the study was approved by the local medical ethic committees.
Results: From January 2018 and July 2019 we consecutively enrolled 206 patients admitted for acute HF. In our analysis 90 patients (43.7%) had ABI index ≤ 0,9 (95% CI 37-51%); in this group, 12 patients only were aware of the disease. The results of the SDCQ showed that 53.3% of the population with ABI ≤ 0.9 had no symptoms suggestive for PAD. Compared with patients with normal or borderline ABI index, patients with ABI ≤ 0,9 more frequently suffer from chronic renal impairment (51.1% and 32.8%, p 0.007) and presented with cardiovascular or cerebrovascular events in the past (55.6% and 37.1%, p 0.008).
Conclusions: PAD is a frequent comorbidity in patients with HF, however this condition is widely under-diagnosed.
To cite this abstract in AMA style:Fantoni C, Mumoli N, Ageno W, Silingardi M, Bertù L, De Dionigi C, Giorgi-Pierfranceschi M, Gessi V, Laganà N, Petroboni B, Dentali F. The Prevalence of Peripheral Artery Disease in Hospitalized Patients with Heart Failure [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/the-prevalence-of-peripheral-artery-disease-in-hospitalized-patients-with-heart-failure/. Accessed January 27, 2022.
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