Abstract Number: OC 54.5
Meeting: ISTH 2022 Congress
Theme: Venous Thromboembolism » VTE Epidemiology
Background: Minor surgical procedures are classified, according to the Dutch national guidelines, as low risk procedures for venous thromboembolism (VTE) and hence, it is not advised to provide thromboprophylaxis. However, they include a wide variation of surgical procedures both in terms of procedure length and tissue damage.
Aims: To determine the VTE risk for several minor surgical procedures compared against one control group.
Methods: Data were used from the MEGA-study (population-based case-control study into causes of VTE) and linked to the Dutch Hospital Registry data. Surgical procedures were assessed individually or grouped together in case of low numbers. Logistic regression was used to estimate odds ratios for the 90-day relative risk for VTE following these procedures, adjusted for important confounders. The odds ratios at 1-year after the procedures were also analyzed.
Results: 3,563 cases and 5,029 controls were assessed whose characteristics are described in table 1. A total of 104 participants, 74 cases and 30 controls, had undergone a minor surgical procedure within 90-days of the index date, resulting in an approximately 3.5-fold (OR 3.5, 95% CI 2.3 to 5.3) overall increased VTE risk (table 2). Venous stripping (OR 7.2, 95%CI 2.4 to 21.2), open hernia repair (OR 3.7, 95%CI 1.2 to 11.6) and laparoscopic cholecystectomy (OR 3.2, 95%CI 1.0 to 10.6) were associated with the highest postoperative risk. The other five procedures were weakly or not associated with an increased risk of VTE.
Conclusion(s): Although the procedures we studied are classified as having a low risk of VTE, we found that venous stripping, open hernia repair and laparoscopic cholecystectomy were associated with a clearly increased risk of VTE.
To cite this abstract in AMA style:
Smeets M, Touw C, Rosendaal F, Nemeth B, Cannegieter S. The risk of venous thromboembolism after minor surgical procedures: A population-based case-control study [abstract]. https://abstracts.isth.org/abstract/the-risk-of-venous-thromboembolism-after-minor-surgical-procedures-a-population-based-case-control-study/. Accessed March 21, 2024.« Back to ISTH 2022 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/the-risk-of-venous-thromboembolism-after-minor-surgical-procedures-a-population-based-case-control-study/