Abstract Number: PB2150
Meeting: ISTH 2020 Congress
Background: Guideline-recommended anticoagulant therapy is widely underused in the setting of cancer-associated thrombosis (CAT), resulting in poor patient outcomes.
Aims: This study’s objective was to assess clinical gaps, attitudes and barriers related to current treatment practices in the setting of CAT.
Methods: A 24-question, online, continuing medical education (CME) survey was developed, including knowledge, case-based (treatment), confidence and attitude questions. Questions were mapped to clinical themes and analyzed to uncover physician gaps by specialty.
Results: A total of 512 physicians, 46% of whom were cardiologists and 20% of whom were hematologists/oncologists completed the survey. 65% of participants were hospital-based. On average 79% of participants manage 1-5 patients with CAT per week, 14% managed 6-10 patients/week and 8% see more than 10 patients/week. Analysis showed that physicians had poor knowledge of LWMH and NOAC clinical trial data in CAT, the risk of bleeding and the current guideline recommendations for managing CAT. The majority also had difficulty selecting appropriate anticoagulant treatment for patients with CAT (Figure). The most important barriers to implementing an effective anticoagulant therapy for patients with CAT were perceived risk of bleeding (56%), cost and poor medication coverage (25%), knowledge of guidelines (23%), and patient adherence (18%). On average only 21% of participants felt confident in selecting the appropriate anticoagulant strategy for patients with CAT.
Conclusions: This educational research study uncovered significant knowledge and treatment gaps among physicians who treat patients with CAT. These findings support the need to continue to educate cardiologists, hem/oncs and other physicians in order to align physicians’ knowledge and performance to improve outcomes and reduce the risk for thrombotic events in patients with CAT.
To cite this abstract in AMA style:Spyropoulos J, Padbury C. Uncovering Clinical Gaps in Treatment of Cancer-Associated Thrombosis: A Clinical Practice Assessment [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/uncovering-clinical-gaps-in-treatment-of-cancer-associated-thrombosis-a-clinical-practice-assessment/. Accessed December 5, 2021.
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