Abstract Number: PB1194
Meeting: ISTH 2020 Congress
Theme: Hemophilia and Rare Bleeding Disorders » Rare Bleeding Disorders
Background: The clinical assessment of the presence and severity of bleeding symptoms is a fundamental step in the evaluation of patients referred for a probable bleedings disorders. The ISTH bleeding assessement tool (ISTH-BAT) was proposed, to standardised a collection of the bleeding history, because the reporting and interpretation of bleeding symptoms is subjective.
Aims: We repport our experience to use ISTH-BAT in diagnosis of bleeding disorders.
Methods: The bleeding symptoms of 1058 patients referred for a probable bleeding disorders and 612 healthy volenteers were assessed retrospectively using ISTH-BAT. Only symptoms and treatment before and at diagnoses are considered. The bleeding score ranged from a minimum of 0 (no symptoms) to a maximum of 56 (blood transfusion or replacement therapy).
Results: In healthy volenteers, sex ratio was 1.25 the most frequents symptoms is menoragia and epistaxis, mean bleeding score was 0 (range 0 to 6).
The use of bleeding score greater than 3 as a screening test for all laboratory phenotype of bleeding disorders has a sensitivity of 57.6% and specificity of 98% ; if we use them only for the diagnosis of severe and moderate phenotype, sensitivity become 86% and the specificity 97%. The use of bleeding score as a screening test for Von Willebrand disease has a sensitivity of 97.89% and specificity of 95.73%.
Conclusions: The value of bleeding score ≥ 3 as is a good screening test of bleeding disorders. This bleeding score is an useful clinical tool for the identification of a possible severe or moderate laboratory phenotype, but this score can´t differentiating between mild bleeding disorders and normal subject.
To cite this abstract in AMA style:
Benlaldj D, Mouedene MA. Use of the ISTH Bleeding Assessement Tool in Diagnosis of Bleeding Disorders in West Algeria [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/use-of-the-isth-bleeding-assessement-tool-in-diagnosis-of-bleeding-disorders-in-west-algeria/. Accessed March 21, 2024.« Back to ISTH 2020 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/use-of-the-isth-bleeding-assessement-tool-in-diagnosis-of-bleeding-disorders-in-west-algeria/