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Validity and Reliability of Self-Administered Thai Pediatric Bleeding Questionnaire (TPBQ) Application to Predict Risk of Bleeding in Pediatric Bleeding Disorders

S. Suwanwijit, D. Sosothikul

Chulalongkorn University, Department of Pediatrics, Bangkok, Thailand

Abstract Number: PB1253

Meeting: ISTH 2020 Congress

Theme: Pediatrics » Bleeding in Neonates and Children

Background: Congenital and acquired bleeding disorders present with various symptoms ranging from mild to severe bleeding. In recent years, there has been attempted to remodel bleeding histories into questionnaire to predict risk of bleeding and describe symptoms severity. Pediatric Bleeding Questionnaire (PBQ) is a pediatric-specific bleeding questionnaire that has been used worldwide. In Thailand, Thai Pediatrics Bleeding Questionnaire (TPBQ) – has been developed but still hasn’t been widely used.

Aims:
(a) To test validity and reliability of self-administered TPBQ application compared to original PBQ in Thai children with bleeding disorders.
(b) To predict risk of bleeding by using self-administered TPBQ application.

Methods: This is a descriptive analytic study. Patients who were diagnosed as bleeding disorders (von willebrand disease (VWD), hemophilia, congenital factor deficiencies and immune thrombocytopenia (ITP)) and visited at King Chulalongkorn Memorial Hospital between 2019-2020 were interviewed by a physician using original PBQ then followed by self-administered TPBQ application in the next two weeks. Results were analysed by using mean and test-retest reliability by intraclass correlation (ICC) and internal consistency.

Results: 41 patients were enrolled in this study (17 patients with VWD, 8 patients with severe hemophilia A, 3 patients with congenital factor VII deficiency and 13 patients with ITP). The mean score in VWD by TBPQ and original PBQ are 5.7 and 6.5, severe hemophilia A are 10.8 and 12.5, congenital factor VII deficiency are 21 and 21, and ITP are 5 and 5.2 respectively. The duration of the interviews for self-administered is 6.4 minutes and expert-administered is 3.8 minutes. The reliability proved excellent with intra-class correlation coefficient 0.86 for test-retest. The internal consistency was strong (Cronbach-alpha=0.92).

Conclusions: Self-administered TPBQ application is comparable to original version of PBQ interviewed by physicians in predicting severity and risk of bleeding in Thai children with bleeding disorders.

To cite this abstract in AMA style:

Suwanwijit S, Sosothikul D. Validity and Reliability of Self-Administered Thai Pediatric Bleeding Questionnaire (TPBQ) Application to Predict Risk of Bleeding in Pediatric Bleeding Disorders [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/validity-and-reliability-of-self-administered-thai-pediatric-bleeding-questionnaire-tpbq-application-to-predict-risk-of-bleeding-in-pediatric-bleeding-disorders/. Accessed May 16, 2022.

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