Abstract Number: PB2372
Meeting: ISTH 2020 Congress
Theme: Venous Thromboembolism and Cardioembolism » VTE Prophylaxis
Background: Scant data are available about the characteristics and optimal treatment of the episode of venous thromboembolism (VTE) occurring in renal transplant (RT) recipients.
Aims: Our study was undertaken to evaluate the characteristics of VTE in RT patients, the type of treatment used in clinical practice and the risk of recurrent VTE.
Methods: We performed a multicentric retrospective observational study among 7 Italian centers. Data were collected in a web based clinical report form with the use of REDCAP system.
Results: 112 patients who received renal transplantation (74 males 64%) and who developed a first episode of VTE after transplantation. Median age (range) at transplantation was 57 (22-76) years. Median time of VTE recurrence from RT was 6 (0.1-213) months; 783% of patients received RT from deceased donor; 10 patients (9.0%) ha kidney and pancreas transplantation. Characteristics of site and type of VTE and treatment of VTE are reported in table 1. During follow-up 84/112 patients stopped anticoagulant treatment. Among them 25 (30%) had recurrent VTE episodes.
Conclusions: We confirm the low rate of pulmonary embolism in RT patients with respect to general population. Instead, RT patients showed a high rate of recurrence accordingly with previous findings.
Patients | 112 |
DVT | 90(85.7%) |
EP | 4 (3.8%) |
DVT/EP | 11 (10.4%) |
Unprovoked | 78 (73.5%) |
Secondary to transient risk factors | 28 (26.5%) |
LMWH/warfarin | 55 (52.4%) |
Warfarin | 41 (39.0% |
DOACs | 9 (8.6%) |
Median (range) duration of treatment, months | 6 (1-144) |
[Site and type of VTE, treatment of VTE]
To cite this abstract in AMA style:
Poli D, Migliaccio L, Antonucci E, Biancone L, Ghigliotti G, La Manna G, Ranghino A, Rigotti P, Tentori S, Zanazzi M, Palareti G. Venous Thromboembolism in Patients with Renal Transplantation [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/venous-thromboembolism-in-patients-with-renal-transplantation/. Accessed December 6, 2023.« Back to ISTH 2020 Congress
ISTH Congress Abstracts - https://abstracts.isth.org/abstract/venous-thromboembolism-in-patients-with-renal-transplantation/