Abstract Number: PB2421
Meeting: ISTH 2020 Congress
Background: Reduction in venous thromboembolism (VTE) mortality rate in Brazil has been less marked in women and in Brazilian’s North/Northeast regions, where VTE management data is scarce.
Aims: To evaluate the profile and management of patients with DVT and/or PE in a private hospital in Salvador, participating in the RIETE registry.
Methods: Consecutive patients from 5/2018 to 8/2019 were evaluated, comparing differences between sexes.
Results: Of the 68 patients, 67.8% were women, the mean age 52 years (± 19.43) and 34.7% of women, vs. 13.6% of men were ≤40 years-old (p=0.72). There were 54.5% PE, 27.9% DVT/PE and 14.7% DVT; more women had PE (58.7% vs. 54.5%) and more men had DVT/PE (42.1% vs. 23.9%). Among the risk factors for VTE, 65.0% were overweight, 29.4% had obesity, 26.4% cancer, 10.5% history of VTE, 7.3% family history of VTE, 11.7% surgery ≤ 2 months, 10.3% immobility >4 days, 5.8% smoking and 4.4% recent travel >6 hours; 32.6% of women used hormones. There were 33.8% of in-hospital VTE; 30.8% were admitted to intensive care unit; the mean length-of-stay was 8±5 days. Among the early discharged, 23,3% (< 48 hours), the initial choice of anticoagulant was enoxaparin, 95.2% and rivaroxaban, 4.8%; the choice for maintenance was rivaroxaban 61.9%, apixaban 28.6% and warfarin, 9.5% (P = 0.038). For those hospitalized ≥48 hours, 36.2% used rivaroxaban, 27.7% apixaban, 21.3% warfarin, 12.8% enoxaparin and 2.1% edoxaban. There were some differences between sexes in baseline characteristics, but none on the choice of anticoagulants or hospital length-of-stay.
Conclusions: This cohort in the Brazil’s Northeast region had more women with VTE, high rates of PE and strong risk factors such as cancer, hormone use and obesity. Enoxaparin was still the main choice for initial treatment, but DOACs were more common in the early discharged without differences between sexes.
To cite this abstract in AMA style:Rocha AT, Pereira de Oliveira M, Emídio de Souza AL. Venous Thromboembolism Profile and Management Differences between Sexes in a RIETE’s Hospital in Brazil [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). https://abstracts.isth.org/abstract/venous-thromboembolism-profile-and-management-differences-between-sexes-in-a-rietes-hospital-in-brazil/. Accessed December 11, 2023.
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