ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1671

C-type Lectin-like Proteins D and E, but Not Botrocetin, Cause Thrombocytopenia during Bothrops jararaca Snakebite Envenomation

A.T.A. Sachetto^1,2, M.E. Peichoto³, J.G. Rosa^1,2, R.J.S. Torquato⁴, D.T. Silva⁵, S.M.T. Serrano⁵, A.S. Tanaka⁴, M.L. Santoro^1,2
Abstract Number: PB1990

Ca2+ Release from Stores Controlled by Sarco/Endoplamic Reticulum Ca2+-ATPase 3 (SERCA3) Is Involved in Endothelial Permeability and Inflammatory Response

K. Beddek, F. Adam, F. Saller, D. Borgel, C. Denis, R. Bobe
Abstract Number: PB0659

Calibrated Automated Thrombogram II: A New Thrombin Generation Test

P.L.A. Giesen¹, A. Gulpen², R. van Oerle², H. ten Cate², M. Nagy², H.M. Spronk²
Abstract Number: PB2359

Can an Effective anticoagulation Clinic Reduce Bleeding Risks?

A. Al-Hassani¹, B. Packham¹, K.M. Ang², R. Patel³
Abstract Number: PB0610

Can Bone Marrow Cells Be Differentiated and Counted Using a Novel Hematology Analyzer?

Z. Kaya¹, S. Kirkiz¹, L. Aydin Kaynar², Z.N. Özkurt², Ü. Koçak¹, M. Yağci²
Abstract Number: PB1315

Can we Predict the Clinical Course of Children with ITP by MPV? A Preliminary Study

Y. Lee¹, H. Yoon¹, S. Cho²
Abstract Number: PB1334

Can we Predict the Outcome of Splenectomy for Primary Immune Thrombocytopenia? Conclusion Based on Systematic Review and Meta-Analysis

M. Mitrovic^1,2, D. Antic^1,2, N. Milic³, M. Virijevic^1,2, Z. Pravdic¹, N. Sabljic¹, N. Pantic¹, N. Suvajdzic Vukovic^1,2
Abstract Number: PB1232

Canadian Guidelines Regarding Safe Blood-draw Volumes for Research in Pediatric Participants

K. Hamilton¹, A.K. Chan², M. Bhatt²
Abstract Number: PB2179

Cancer Associated Thrombosis: Are DOACs a Treatment Option? Systematic Review and Meta-analysis of Randomised Controlled Trials

R. Alikhan, M. Rees
Abstract Number: PB2173

Cancer Patients Has Lower Plasmin Generation by Simultaneous Thrombin and Plasmin Assay Evaluation

G. da Silva Souza Gois, M. Evelyn Alves de Almeida, T. Ramires Rodrigues Alencar, S. Aparecida de Lima Montalvão, B. Moraes Martinelli, I. Macedo Toni, J. Barreto Carvalheira, N. Adami Andreollo, M. Etchebehere, J. Cesar Teixeira, J. Maria Annichino-Bizzacchi, ADVENTH Cancer Investigators
Abstract Number: PB2177

Cancer Site and Distant Metastasis at Diagnosis Predict the Risk of VTE in Cancer

S.K. Braekkan¹, M.E. Gabrielsen², B. Brumpton², K. Hveem², J.-B. Hansen¹
Abstract Number: PB0439

Canonical Signaling Pathways Dysfunctions in the Development of Major Cardiovascular Complications, Circulating Micrornas as Novel Biomarkers and their Link to Inflammation in Diabetic Patients

C. Eyileten¹, J. Pordzik¹, A. Soplinska¹, J. Jarosz-Popek¹, P. Czajka¹, Z. Wicik^1,2, M. Wolska¹, W.-L. Liu¹, S. De Rosa³, D. Mirowska-Guzel¹, M. Postula¹
Abstract Number: PB1863

Caplacizumab in a Case of Acquired Thrombotic Thrombcytopenic Purpura (TTP) Poor Responsive to Plasma Exchange and Immunosuppressive Therapy

A. Molteni, C. Dellanoce, A. Pasini, O. Paoletti, A. Mancini, V. Cancelli, M. Tajana, M. Tala, S. Belletti, R. Morandini, C. Fiamenghi, P. Spedini, S. Testa
Abstract Number: PB0737

Carboxypeptidase U (CPU, TAFIa, CPB2) Generation in Acute Ischemic Stroke Patients Undergoing Thrombolysis and Endovascular Thrombectomy

J.C. Mertens¹, V. Blanc-Guillemaud², K. Claesen¹, D. Leenaerts¹, B. Tyl², P. Cardona³, D. Hendriks¹, C.A. Molina^4,5
Abstract Number: PB0137

Cardiac Myosin Promotes Thrombin Generation and Coagulation in vitro and in vivo

M. Shukla¹, H. Deguchi¹, J. Zilberman-Rudenko^1,2, Y. Oyama³, T. Eckle³, Z. Guo¹, S. Lear¹, W. Shen¹, T. Wyseure¹, L. Mosnier¹, J. Orje¹, Z. Ruggeri¹, O. McCarty², J. Griffin¹
Abstract Number: PB0934

Cardiovascular Risk Factor Profile among North-Eastern Brazilian Adults with Haemophilia

R.M. Camelo^1,2,3, B.P. Duarte², M.C.B. Moura², N.C.M. Costa², I.M. Costa², C.G.P. Roncal², A.M. Vanderlei², T.M.R. Guimaraes², C. Caram-Deelder³, S.C. Gouw³, S.M. Rezende¹, J.G. van der Bom^3,4
Abstract Number: PB0071

Cardiovascular Risk in Systemic Lupus Erythematosus

M. Kechida¹, A. Fraj¹, S. Daada¹, R. Klii¹, S. Hammami¹, M. Sassi², I. Khochtali¹
Abstract Number: PB2194

Carrier Frequencies of Antithrombin-, Protein C-, or Protein S-deficient Variants Estimated Using a Public Database and Expression Experiments

K. Maruyama, K. Kokame
Abstract Number: PB1923

Catastrophic Antiphospholipid Syndrome, Kikuchi-Fujimoto Disease and Adult-Onset Still Disease: An Unusual Association

S.D.A. Peres¹, G. Remondino², F. Aranda¹, A. Lucero¹, G. Lencinas¹, E. Cunto¹, G.F. de Larrañaga¹
Abstract Number: PB2342

Catheter-associated Thrombosis at the Hematology Center: Analysis of 2212 Medical Records from a Developing Country

L. Hambardzumyan^1,2, H. Grigoryan^1,3, L. Mkrtchyan², M. Badikyan^2,4, S. Danielyan², G. Tamamyan^1,5, N. Sargsyan⁶, L. Petrosyan⁶, L. Sahakyan², H. Khachatryan⁶
Abstract Number: PB2143

Catheter-Associated Upper Extremities Deep Vein Thrombosis in Cancer Patients: Does Anticoagulation Time Matter?

A. Dalla Salda, E. Spaggiari, B. Abbate, M. Iotti, L. Depietri, S. Corradini, I. Lambertini, M.R. Veropalumbo, A. Ghirarduzzi
Abstract Number: PB1346

CD4⁺ T Cell Expression of IL-10 Compared to IL-17 is Lower in Patients with Immune Thrombocytopenia (ITP) Who Do Not Respond Clinically to High Dose Corticosteroid

M. Stimpson¹, P. Lait¹, L. Schewitz-Bowers¹, E. Williams¹, R. Lee^1,2, C. Bradbury^2,3
Abstract Number: OC 04.3

CD84 Links T Cell and Platelet Activity in Cerebral Thrombo-inflammation in Acute Stroke

D. Stegner¹, M.K. Schuhmann², G. Stoll², M. Bieber², T. Vögtle¹, S. Hofmann¹, M. Seyhan³, A.M. Kollikowski⁴, V. Klaus¹, P. Heuschmann³, M. Pham⁴, B. Nieswandt¹
Abstract Number: PB2001

Cell-free DNA and Citrullinated Histone H3 Plasma Levels Improve the Prediction of Mortality in Septic Patients

M. Moiana, E. Cunto, C. Dominguez, V. Chediack, S. Perés, G. de Larrañaga
Abstract Number: PB0445

Cell-free DNA Is Elevated in Chronic Myeloproliferative Neoplasms: Correlation with Thrombosis and Disease Progression

G. De Luca¹, C.P. Marin Oyazún¹, A.C. Glembotsky¹, M. Gutierrez², M. Castro Rios³, B. Moiraghi⁴, A. Vicente⁵, F. Sackmann⁶, G. Bendek⁷, A. Varela⁴, V. Cortes Guerrieri⁸, V. Verri⁸, V. Caula⁸, V. Vallejos⁹, P.R. Lev¹, N.P. Goette¹⁰, D. Ayala¹, R.F. Marta¹, M. Schattner¹¹, P.G. Heller¹
Abstract Number: PB0722

Cellular Factor XIII Externalization in Platelets and Platelet Microparticles Induced by Receptor Mediated and Non-Receptor Mediated Platelet Activation

L. Somodi¹, I. Beke Debreceni², H. Bárdos³, Á. Bana³, J. Kappelmayer², L. Muszbek¹
Abstract Number: PB2163

Cerebral Sinus Venous Thrombosis in Children with Leukemia: Single-institution Report

I. Melnichenko^1,2, L. Krmoyan^1,2, H. Khachatryan³, A. Zakharyan^2,4, N. Martirosyan², S. Hovhannisyan², M. Gizhlaryan^1,2, S. Danielyan⁵, G. Tamamyan^1,2, L. Vagharshakyan^1,2
Abstract Number: PB2468

Cerebral Vein Thrombosis Treatment with Direct Oral Anticoagulants: A Case Series

S. Barbar¹, F. Boscaro², E. De Bon¹, A. Bozzolin², L. Scarano¹, F. Fabris², M.T. Sartori²
Abstract Number: PB0583

Challenges in Anticoagulation Management at an Academic Medical Center, 20 Years of Clinical Observations

S. Kogan
Abstract Number: PB1250

Challenges in Diagnosing and Treating Polycythemia Vera with Acquired von Willebrand Disease in a Pediatric Patient

J. Jain, A. Tang, C. Bennett
Abstract Number: PB0749

Changes in Fibrinolytic Factors in a Simulated Extracorporeal Membrane Oxygenator Circuit

A. Doyle¹, N. Gooby², K. Parmar¹, K.A. Breen², N.A. Barrett², A. Retter², B.J. Hunt¹
Abstract Number: PB0063

Changes in the Hemostasis System in Athletes

N. Vorobyeva¹, N. Malishkina²
Abstract Number: PB0015

Changes of Soluble Fibrin-Monomer Complex Concentration in Different Types of Coronary Artery Disease

Y. Tyravska¹, V. Lizogub¹, D. Pliskevych², T. Vovk³, O. Savchuk³
Abstract Number: PB0206

Characterisation and Evaluation of a Candidate Bethesda Assay Reference Reagent Developed from Recombinant, Patient-Derived FVIII Inhibitors

C. Coxon¹, J. Beavis², X. Yu³, S. Diamond³, A. Riches¹, S. Raut¹
Abstract Number: PB2187

Characterisation of a Novel F5 Gene Mutation (Ala2114Asp, Factor V Besançon) Associated with Factor V Deficiency and Recurrent Venous Thrombosis

E. Castoldi¹, N. Hézard², G. Mourey³, K. Wichapong¹, M. Ibrahim-Kosta⁴, M.C.L.G.D. Thomassen¹, A. Fournel³, M.-C. Alessi⁴, T.M. Hackeng¹, J. Rosing¹, P.-E. Morange⁴
Abstract Number: PB2240

Characterisation of Antithrombin p.Thr147Ala, the First Common Founder Variant from African Origin Responsible for Inherited Antithrombin Deficiency

B. de la Morena-Barrio¹, J. Padilla², I. Pareyn³, C. Bravo-Pérez², K. Vanhoorelbeke³, I. Martínez-Martínez², V. Vicente², J. Corral², K. Jochmans⁴, M.E. de la Morena-Barrio², C. Orlando⁴
Abstract Number: PB0376

Characterisation of Plasma Microvesicles in Type 2 Diabetes mellitus Patients with and without Microalbuminuria

A. Vaidya¹, K. Gooding¹, A. Shore¹, G. Pula^1,2
Abstract Number: PB2340

Characterising the Burden of Hospital-acquired Venous Thromboembolism Arising during Admission and Following Discharge in an Irish Hospital Group Serving a Population of over One Million Individuals

K. Ewins^1,2, M. Day³, M. Fitzpatrick³, N. Bannon³, T. Breslin^2,4, K. Murphy^2,5, S.W. Maung^2,3,6, A.-M. O'Neill⁷, F. Ni Ainle^1,2,8, B. Kevane^1,2,3
Abstract Number: PB1374

Characteristics and Outcome of Patients with Thrombocytopenia Secondary to Acute Cytomegalovirus Infection: Case Series and Literature Review

T. Shragai¹, E. Lebel², D. Deshet³, D. Varon^1,2, I. Avivi^1,4, I. Kirgner¹, N. Sarid¹
Abstract Number: PB0107

Characteristics and Recurrence of Acute Ischemic Stroke in Children: An Examination Using Real World Data

J. Hardin^1,2, L. Wang³, Z. Yuan³, H. Patino⁴, J. Weaver^1,2
Abstract Number: PB1319

Characteristics of Patients with Cyclic Thrombocytopenia: An Observational Cohort Study

O. Steinbrecher¹, L. Eischer¹, H. Sinkovec², M. Mitrovic³, S. Eichinger¹, P.A. Kyrle¹
Abstract Number: PB0101

Characterization and Antithrombotic Treatment of Patients with Acute Ischemic Stroke and No Atrial Fibrillation: A Real-world Study

L. Wang, J. Weaver, J. Hardin, E. Barnathan, J. Foody, G. Peters, Z. Yuan
Abstract Number: PB1195

Characterization and Management of Patients with Mild or Moderate Hereditary Factor X Deficiency: A Retrospective Chart Review

S. Acharya¹, C. Sabo², M. Chitlur³
Abstract Number: PB1155

Characterization of Factor IX-FIAV: A Factor IX Variant that Displays Cofactor-Independent Activity

V.J.F. Strijbis¹, K.L. Cheung¹, P. Konstantinova², Y.P. Liu², S. van Deventer², M.H.A. Bos¹
Abstract Number: PB1413

Characterization of Murine Monoclonal Anti-PF4/Polyanion Antibodies, as Potential Useful Tools for Studies on Typical and Autoimmune HIT

C. Vayne^1,2, T.-H. Nguyen^3,4, J. Rollin^1,2, N. Charuel¹, A. Poupon^5,6, C. Pouplard^1,2, Y. Gruel^1,2, A. Greinacher³
Abstract Number: PB1159

Characterization of Neutralizing Anti-emicizumab Antibody Developed in a Hemophilia A Patient

C. Valsecchi¹, M. Gobbi², L. Schiavone¹, M. Beeg², T.E. Adams³, M.E. Mancuso¹, J.A. Huntington³, F. Peyvandi^1,4
Abstract Number: PB1644

Characterization of the Hypercoagulable State and NETosis in Systemic Lupus Erythematosus

E. Monzón Manzano¹, I. Fernández Bello¹, Á. Robles Marhuenda², R. Justo Sanz¹, P. Acuña Butta¹, F.J. López Longo³, M.T. Álvarez Román¹, V. Jiménez Yuste¹, N. Butta Coll¹
Abstract Number: OC 08.5

Characterization of the Protein Profile in Thrombi of Patients with Ischemic Stroke and Identification of Potential Biomarkers as Predictors of Negative Clinical Evolution

C. Lopez-Pedrera¹, A. Ibañez-Costa¹, C. Perez-Sanchez¹, M. Luque-Tevar¹, A.M. Patiño-Trives¹, M.D.C. Abalos-Aguilera¹, N. Barbarroja¹, J.J. Ochoa-Sepulveda², F. Delgado-Acosta², R. Oteros-Fernandez², F. Velasco³
Abstract Number: PB1699

Characterization of Thrombus Heterogeneity and Dynamics of Formation on Collagen Spots in a Parallel-plate Flow Chamber

A. Ryabykh¹, E. Beresneva^2,3, D. Nechipurenko^1,2,3, M. Panteleev^1,2,3
Abstract Number: PB1548

Characterization of Type 2B VWD in the US Zimmerman Program

P. Christopherson, V. Flood, S. Haberichter, T. Slobodianuk, P. Morateck, R. Montgomery, Zimmerman Program Investigators
Abstract Number: PB2049

Characterization of VKA Control in Patients with Thrombotic and Major Hemorrhagic Events in Anticoagulation Hematology Units: Results from the EVENTHO Study

O. Gavín¹, V. Roldán², A. Santamaría³, P. Llamas⁴, D. Arumí⁵, S. Fernández de Cabo⁵
Abstract Number: PB1659

Characterizing Platelet Granules of von Willebrand Disease Patients Using Super-Resolution Structured Illumination Microscopy

M. Swinkels¹, J.A. Slotman², F.W.G. Leebeek¹, J. Voorberg³, R. Bierings¹, A.J.G. Jansen^1,3
Abstract Number: OC 02.2

Chemical Modulation of Fibrinogen Production and its Impact on Venous Thrombosis

R. Vilar¹, S.W. Lukowski², M. Garieri¹, C. Di Sanza¹, M. Neerman-Arbez^1,3, R.J. Fish¹
Abstract Number: PB1807

Chemotherapy – Induced Thrombocytopenia in Pediatric Acute Lymphoblastic Leukemia: A Single-institution Report

M. Gizhlaryan^1,2, L. Sahakyan³, L. Krmoyan^1,2, M. Petrosyan^1,2, I. Melnichenko^1,2, M. Anastasiadi^1,2, H. Danelyan^1,2, S. Danielyan³, G. Tamamyan^1,2, L. Vagharshakyan^1,2
Abstract Number: PB1236

Chronic Refractory Immune Thrombocytopenia is Associated with a High Frequency of Potentially Damaging Variants in Immune Genes

S. Zhao
Abstract Number: PB1769

Chronically Elevated Interleukin-6 Levels in Mice Lead to a Disturbance in the Coagulation System

T. Knopp^1,2, J. Lagrange^1,3, R. Schüler^1,4, F. Ridder^1,4, J. Wild^1,2, H. Rossmann⁵, H.M.H. Spronk⁶, T. Münzel², B. Lämmle^1,7,8, W. Ruf¹, P. Wenzel^1,2, A. Waisman⁴, S. Karbach^1,2
Abstract Number: PB0465

Circulating MicroRNA Levels Indicate Platelet Activation in Endotoxemia Despite Platelet P2Y₁₂Inhibition

A. Braza Boils*^1,2, T. Barwari*¹, C. Gutmann*¹, M.R. Thomas³, H.M. Judge⁴, A. Joshi¹, R. Pechlaner⁵, S. Skalicky⁶, M. Hackl⁶, M. Shankar-Hari⁷, R.A. Ajjan⁸, I. Sabroe⁴, R.F. Storey⁴, M. Mayr¹, These three authors contributed equally to this work
Abstract Number: PB0437

Circulating MicroRNAs and Platelet Extracellular Vesicles as Novel Biomarkers in Acute Ischaemic Stroke

C. Eyileten¹, P. Czajka¹, D. Jakubik², J. Jarosz-Popek¹, Z. Fitas¹, A. Nowak¹, L. Zareba¹, G. von Baumgarten¹, S. De Rosa³, A. Gasecka⁴, M. Wolska², L. Sharif², D. Mirowska-Guzel¹, A. Czlonkowska⁵, M. Postula¹
Abstract Number: PB1404

Circulating Myeloid-related Protein (MRP)-8/14 May Contribute to Suboptimal Response to Low Dose Aspirin in Patients with Type 2 Diabetes mellitus

P.G.M. Simeone, R. Tripaldi, R. Liani, S. Ciotti, A. Boccatonda, D. D'Ardes, F. Santilli
Abstract Number: PB0209

Circulating T Helper 17 Cells (Th17) Increase at a Higher Rate than Tregs in Previously Untreated Patients with Severe Hemophilia A Who Develop Inhibitors During the First 50 Exposure Days to rFVIII

D. Brown¹, V. Berg², J. Blatny³, K. Fijnvandraat⁴, J. Klintman⁵, C. Male⁶, C. McGuinn⁷, S. Meeks⁸, E. Mullins⁹, V. Radelescu¹⁰, M. Ragni¹¹, M. Recht¹², E. Santagostino¹³, A. Shapiro¹⁴, J. Staber¹⁵, H. Yaish¹⁶, P. LeBeau¹⁷, J. Bowen¹⁷, B. Gangadharan¹⁸, B. Reipert¹⁸
Abstract Number: PB1932

CliA Immunoassay: Better Identification of High Thrombotic Risk Triple Positive Antiphospholipid Patients

B. Montaruli¹, A. Romito¹, C. Guiotto¹, T. Bertero², P. Sivera³, D. Cosseddu¹
Abstract Number: PB1867

Clinical Analysis of 83 Patients with Thrombotic Thrombocytopenic Purpura

W. Xiyan, L. Xiaofan, X. Feng, L. Wei, C. Yunfei, H. Yueting, F. Rongfeng, Z. Lei, Y. Renchi
Abstract Number: PB/CO02

Clinical and Computed Tomography Characteristics of COVID-19 Associated Acute Pulmonary Embolism: A Different Phenotype of Thrombotic Disease?

L.F. van Dam¹, L.J.M. Kroft², L.I. van der Wal³, S.C. Cannegieter⁴, J. Eikenboom¹, E. de Jonge³, M.V. Huisman¹, F.A. Klok¹
Abstract Number: PB1889

Clinical and Economic Impacts of a New Rapid ADAMTS-13 Assay for the Diagnosis of Suspected Thrombotic Thrombocytopenic Purpura

C. Novelli¹, B. Montaruli², L. Solfietti³, A. Valpreda⁴, M. Bazzan³, B. Basolo³, I.L.A. Beverina¹, M. Milan⁵, B. Brando¹
Abstract Number: PB2186

Clinical and Laboratory Characteristics of Patients with Hereditary Thrombophilias in the North-Western Region of Russia

O. Soldatenkova^1,2, V. Soldatenkov¹, L. Papayan¹, S. Kapustin¹, N. Gordeev², N. Mineeva¹, A. Chechetkin¹, K. Komissarov¹
Abstract Number: PB1340

Clinical and Laboratory Factors Affecting Chronicity in Children Diagnosed with Immune Thrombocytopenia

Y. Ay¹, H. Sarbay²
Abstract Number: PB1495

Clinical and Molecular Characterization of Chinese Patients with Wiskott-Aldrich Syndrome

X. Zhang¹, D. Zhang², R. Yang², F. Zhou¹
Abstract Number: PB1561

Clinical and Phenotypic Evaluation of Patients with Low von Willebrand Factor

O. Seidi Zadeh, M. Ahmadinejad, M. Mojtabavi, S. Homayoun
Abstract Number: PB1304

Clinical and Radiological Outcome in a Single Center Cohort of Pediatric Patients with Focal Cerebral Arteriopathy (FCA). Safety of Antithrombotic Prophylaxis and Therapy

A. Beccaria¹, E.J. Svahn², M. Bertamino³, M. Severino⁴, A. Pistorio⁵, L. Banov², A.C. Molinari²
Abstract Number: PB2040

Clinical Case: Reversal of Dabigatran Levels in Patients with Renal Insufficiency that Have Required the use of Idarucizumab

A. Tugues Peiró¹, C. Marzo Alonzo¹, E. Vicente Pascual¹, A. Ferrero Campos¹, A. Ruiz¹, M.E. Rivero¹, A. Garcia Guiñon¹, A. Luaña¹, C. Chavez¹, M. Teixido¹, X. Gomez², T. Garcia¹
Abstract Number: PB2448

Clinical Characteristics and Outcomes of Non-cancer, Non-CVC Associated upper Extremity DVT

O. Cohen¹, L. Bertú¹, E. Antonucci², G. Palareti², W. Ageno¹
Abstract Number: PB1171

Clinical Characteristics of Patients with Rare Bleeding Disorders: Real-Life Data from the Netherlands (RBiN Study)

J.L. Saes^1,2, M.J.A. Verhagen^1,2, K. Meijer³, M.H. Cnossen⁴, R.E.G. Schutgens⁵, M. Peters⁶, L. Nieuwenhuizen^2,7, F.J.M. van der Meer⁸, I.C. Kruis⁹, W.L. van Heerde^2,10,11, S.E.M. Schols^1,2, RBiN Study Group
Abstract Number: PB0613

Clinical Exomes for the Diagnosis of Inherited Bleeding, Thrombotic and Platelet Disorders: The Belgian Experience

C. Van Laer^1,2, M. Jacquemin^1,2, C. Thys¹, E. Van Hoof³, A. Corveleyn³, K. Peerlinck^1,4, K. Freson¹
Abstract Number: PB1094

Clinical Immunogenicity of Valoctocogene Roxaparvovec in GENEr8-1, a Phase 3 Study of AAV5-Mediated Gene Therapy Encoding Human FVIII for the Treatment of Hemophilia A

B. Long, C. Vettermann, A. Lawal, B. Kim, W.Y. Wong, G. Hayes, T. Seitel, K. Lau, K. Sandza, K. Patton, X. Yang, B. Schweighardt
Abstract Number: PB0077

Clinical Implications of White Blood Cell Count and Platelet Indices in Individuals with Risk Factor of Coronary Artery Disease

S. Lasom¹, K. Chainam²
Abstract Number: PB1080

Clinical Improvement of Haemophilic Arthropathy in a Female Pediatric Patient with Severe Hemophilia A Following Treatment with Emicizumab

F. Xavier^1,2, C. McShea², J. Squires¹, S. Tadros¹, M. Ragni^3,4
Abstract Number: PB2352

Clinical Indications and Efficacy of Low Molecular Weight Heparin (LMWH) in Pregnancy

R. Akbar¹, M. Javed²
Abstract Number: PB2102

Clinical Outcome of Anticoagulation for Acute Venous Thromboembolism Associated with Different Types of Cancer

W. Wysokinski¹, D.T. Vlazny¹, R.D. McBane¹, D.O. Hodge², D.A. Froehling¹, D.E. Houghton¹, L.G. Peterson¹, A.I. Casanegra¹
Abstract Number: PB2146

Clinical Outcome of Splanchnic and Usual Site Venous Thrombosis in Patients with Solid Cancer

E. Valeriani¹, M. Di Nisio², N. Riva³, L.M. Caiano⁴, E. Porreca¹, S.M. Bang⁵, J. Beyer-Westendorf⁶, M.T. Sartori⁷, G. Barillari⁸, R.C. Santoro⁹, R. Duce¹⁰, P. Kamphuisen¹¹, A. Alatri¹², A. Malato¹³, G. Vidili¹⁴, D. Oh¹⁵, S. Schulman¹⁶, W. Ageno⁴, International Registry on Splanchnic Vein Thrombosis (IRSVT) Study Group
Abstract Number: PB0288

Clinical Outcome of Using Three-Factor Prothrombin Complex Concentrate in Patients with Major Bleeding Associated with Factor Xa Inhibitor

T. Raksintham¹, Y. Chinthammitr², T. Ruchutrakool³, B. Suwannawiboon³
Abstract Number: PB2064

Clinical Outcomes for Patients of High Body Weight on Apixaban or Rivaroxaban

G. Bahra, Z. Mahir, V. Collings, K. Breen, B. Hunt, A. Cohen
Abstract Number: PB0600

Clinical Performance of the Tina-Quant D-Dimer Gen 2 Assay on the Cobas t 711 Analyser for Evaluation of Patients with Suspected Deep Vein Thrombosis (DVT) and/or Pulmonary Embolism (PE)

T. Bertsch¹, S. Blaschke², R. Body³, S. Davidson⁴, G. Guo⁵, D. Horner⁶, Y. Sun⁷, L. Turnes⁸, U. Sonner⁹, M. Hoffmann⁷
Abstract Number: PB1347

Clinical Practise of SMOG System for Assessing Severity of Hemorrhagic Manifestations of Immume Thrombocytopenia (ITP) in Children

D. Sigunova, L. Zhukova, K. Papayan, A. Morozova
Abstract Number: PB0388

Clinical Presentation and Management of Homozygous Protein C Deficiency: Cukurova Experience

N. Boz, H.I. Sasmaz, M. Cil, G. Leblebisatan
Abstract Number: PB2176

Clinical Presentation and Outcomes of Cancer-associated Distal Deep Vein Thrombosis: Data from the RIETE Registry

J.-P. Galanaud¹, J. Trujillo-Santos², B. Bikdeli³, V. Rosa⁴, A. Visona⁵, J.A. Nieto⁶, L. Mazzolai⁷, S. Soler⁸, M. Monreal⁹, RIETE Investigators
Abstract Number: PB1538

Clinical Presentation of Von Willebrand Disease in a Developing Country-A Cross Sectional Study

A. Fatima
Abstract Number: PB0872

Clinical Review of Patients with Haemophilia (PwH) in a Malaysian Tertiary Center

Y.L. Boo¹, C.C.K. Liam¹, K.Y. Yong¹, R.J. Fann^1,2, G.W.C. Lee¹, G. Wilfred¹, J. Sathar¹
Abstract Number: PB0216

Clinical Significance of T-cell Subsets for the Inhibitor Development in Pediatric Hemophilia A Patients

Z. Chen, Z. Li, G. Li, Y. Zhen, K. Huang, R. Wu
Abstract Number: PB2317

Clinical Spectrum and Prothrombotic Risk Factors of Cerebral Venous Sinus Thrombosis in Children

Y. Düzenli Kar¹, Z.C. Özdemir², C. Yarar³, K.B. Çarman⁴, N. Tekin⁵, Ö. Bör²
Abstract Number: PB0309

Clinical Study of Children’s Intracranial Hemorrhage in Single Hemophilia Center in China

X. Feng¹, H. Ge²
Abstract Number: PB1440

Clinical Use of Carica Papaya Leaf Extract in Thrombocytopenia in Bernard-Soulier Syndrome

O. El Safi¹, M. Fathy¹, S. Osama², A. Osama³, S. Al Auch³
Abstract Number: PB0696

Clinical Utilization of Lupus Anticoagulant Testing in a Large Hospital System

A. Vijayanarayanan, R. Laforest, S. Philip, J. Hayward, I. Lopez-Plaza
Abstract Number: PB0996

Clinical Validation of Population Pharmacokinetic Model for Plasma-Derived Factor VIII/VWF Comparing 3 Years Follow-up

J.E. Megías-Vericat¹, S. Bonanad², S. Haya², A.R. Cid², M.R. Marqués³, E. Monte-Boquet³, S. Pérez-Alenda⁴, P. Bosch², F. Querol⁴, J.L. Poveda³
Abstract Number: PB0575

Clinical Validation of the T-TAS 01 PL Assay in Patients Taking Antiplatelet Therapy

J. Dahlen¹, P. Gurbel², A.H.B. Wu³, K. Bliden², C.-M. Ong³, U. Tantry², K. Hosokawa⁴
Abstract Number: PB0574

Clinical Validation of the T-TAS 01 PL Assay in Patients with von Willebrand Disease and Glanzmann´s Thrombasthenia

J. Dahlen¹, S.R. Lentz², A.H.B. Wu³, M. Fiore⁴, A. Leavitt³, P. Gurbel⁵, C.-M. Ong³, K. Bliden⁵, T. Peters², U. Tantry⁵, K. Hosokawa⁶
Abstract Number: PB1438

Clinical, Morphological and Functional Platelet Tests in Inherited Thrombocytopenia

F. Gonçalves¹, F. Vasconcelos², E. Cruz³, M. Pereira³, M. Carmona⁴, S. Esteves⁵, I. Freitas⁶, M. Lima³, S. Morais³
Abstract Number: PB1557

Clinically Relevant Differences between Two New Generation VWF: GPIbR Assays in a Patient with Acquired von Willebrand Syndrome – Case Report

K. Mayger^1,2, A. McCormick^1,2, S. Austin²
Abstract Number: PB0689

Clinically Significant Disagreement between Point-of-Care INR and Central Laboratory-assessed INR in Acute Stroke Patients

E. Salazar, B. Castillo, J. Chen, C. Leveque
Abstract Number: PB1503

Clinico-pathological Spectrum of GlanzmannThrombasthenia

D. Chandra, R. Gupta, K. Rahman, M. Singh, S. Nityanand
Abstract Number: PB0001

Clopidogrel Resistance and P2y12 Receptor Gene Polymorphisms in Patients with Non-ST Elevated Acute Coronary Syndrome

D. Shorikova¹, E. Shorikov¹, P. Shorikov²
Abstract Number: PB0458

Clot Contraction Drives Structural Redistribution of Platelets, Fibrin and Red Blood Cells through Active Cell Sorting

V. Tutwiler¹, X. Chen², R. Litvinov^1,3, R. Khismatullin⁴, J. Weisel¹, V. Shenoy²
Abstract Number: PB0018

Clot Formation, Ultrastructure and Lysis in Patients with Acute Phase Myocardial Infarction

S.R. Baker^1,2, A. Siniarski^3,4, C. Duval², G. Gajos^3,4, J. Nessler³, R.A.S. Ariens²
Abstract Number: OC 06.3

Clotting Promotes Glioblastoma Progression

L.M. Knowles¹, C. Wolter¹, R. Ketter², S. Urbschat², S. Linsler², S. Müller², A. Müller³, H. Eichler¹, J. Pilch¹
Abstract Number: PB1286

Coagulation Activation Via Extrinsic Pathway Is the Major Cause of Hypercoagulation in Newborns during First Days of Life

E. Koltsova^1,2, E. Lipets^1,2, B. Arutunyan³, N. Tetruashvili³, E. Balashova³, A. Karavaeva³, A. Balandina^1,2
Abstract Number: PB0789

Coagulation and Inflammation Genes Are Differently Expressed during the Acquired Coagulation Disorder Induced by Snake Envenomation

A.T.A. Sachetto¹, J.R. Jensen², M.L. Santoro¹
Abstract Number: PB0250

Coagulation Assays Based on Surface-Mimicking Antibodies against Factor XII

M. Heestermans¹, C. Naudin², K. Klaetschke¹, C. Deppermann¹, G. Pula¹, L.M. Butler², E.X. Stavrou^3,4, T. Renné¹
Abstract Number: PB0415

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Bleeding Phenotype

S. Subramaniam^1,2, S. Eisa-Beygi³, R. Ramachandran⁴, C. Fletcher², H. Weiler¹
Abstract Number: PB0413

Coagulation Factor Xa [(Recombinant) Andexxa®] for Reversal of Apixaban and Rivaroxaban in Patients Diagnosed with Intracranial Hemorrhage

M. Vestal¹, K. Hodulik¹, J. Mando-Vandrick¹, M. Friedland², T. Ortel³, I. Welsby²
Abstract Number: PB1790

Coagulation Factor XII Binds to the Opportunistic Pathogen, Candida albicans and Promotes Biofilm Formation

M.L. Williams¹, D.S. Childers¹, A.C. Brand², N.J. Mutch¹
Abstract Number: PB1776

Coagulation Factor XII Signaling Triggers Inflammasome-associated Renal Damage in Diabetic Nephropathy

A. Elwakiel¹, K. Shahzad¹, R. Rana¹, D. Gupta¹, I. Gadi¹, S. Kohli¹, T. Renné², B. Isermann¹
Abstract Number: PB1778

Coagulation Markers, Neutrophil Extracellular Traps and Thrombin Generation Test, in the Detection and Risk Stratification of Prostate Cancer

J. Oto¹, Á. Fernández-Pardo¹, E. Plana¹, A. Cañada², F. Cana¹, M. Martínez-Sarmiento³, C.D. Vera-Donoso³, F. España¹, P. Medina¹
Abstract Number: PB1788

Coagulation Profile in Patients with Pneumonia Assessed by Thrombin Generation Procedures

E. Scalambrino¹, M. Clerici¹, S. Rossi², V. Chantarangkul¹, V. Monzani², F. Peyvadi^1,3, A. Tripodi¹
Abstract Number: PB0283

Coagulation Research in Paediatric ECMO: Delayed Consent to Improve Enrolment

S. Van Den Helm¹, J.G.F. Drop^2,3, E.W. Wildschut³, R. Barton^1,4,5, H.P. Yaw^1,4, N. Letunica¹, F. Newall^1,4,5, A. Johansen^6,7, D. Best^6,7, J. McKittrick⁶, G. MacLaren^1,6,8, R. Chiletti^6,7, W. Butt^4,6,7, Y. d'Udekem^4,9, C.H. van Ommen², V. Ignjatovic^1,4, P. Monagle^1,4,5
Abstract Number: PB0285

Coagulation Research in Paediatric ECMO: The Need for a Common Languagecoagulation Research in Paediatric ECMO: The Need for a Common Language

J. Drop^1,2, S. Van Den Helm³, E. Wildschut², R. Barton^3,4,5, H.P. Yaw^3,4, N. Letunica³, F. Newall^3,4,5, A. Johansen^6,7, D. Best^6,7, J. McKittrick⁶, G. MacLaren^3,6,8, S. Horton^4,9, R. Chiletti^6,7, W. Butt^4,6,7, Y. d'Udekem^4,9, C. van Ommen¹, V. Ignjatovic^3,4, P. Monagle^3,4,5
Abstract Number: PB0800

Coagulopathy in Pediatric Patients with Hemophagocytic Lymphohistiocytosis

M. Shamoun¹, K. Walkovich², A. Weyand²
Abstract Number: PB1909

Cohort of Patients with Triple Antiphospholipid Antibodies: Differences between Asymptomatic and Symptomatic Individuals

P. Casais^1,2, J. Salviú², S. Meschengieser²
Abstract Number: PB0944

Coinfection by Hepatitis B, C and HIV in Patients with Haemophilia

D. O W Rodrigues¹, O. F Santos², T. S Esposito³, T. M M Paz⁴, J. D Rezende⁴, A. C A Santos⁴, L. O W Rodrigues⁵
Abstract Number: PB1625

Cold over Room Temperature Storage of Apheresis Platelets Better Preserves Hemostatic Function out to 21 Days

S.M. Shea, K.A. Thomas, P.C. Spinella
Abstract Number: PB1832

Cold Storage of Apheresis Platelets Promotes IL-8 Release in Platelet: Leukocyte Co-cultures

K.A. Thomas, S.M. Shea, P.C. Spinella
Abstract Number: PB1182

Collagen Turnover and Plasma Ascorbic Acid Levels in Patients Suspected of Inherited Bleeding Disorders Harboring Variants in Collagen-related Genes

M. Fager Ferrari¹, E. Zetterberg¹, M. Rossing², T. Manon-Jensen³, M. Pehrsson³, M. Karsdal³, J. Lykkesfeldt⁴, E. Leinoe⁵
Abstract Number: PB1650

Collagen-Induced Thrombocyte Aggregation in Essential Arterial Hypertension with Subclinical Organ Damage

D. Shorikova¹, E. Shorikov¹, P. Shorikov², O. Khukhlina¹
Abstract Number: PB1959

Colonization with the Minimal Microbial Consortium Altered Schaedler Flora Hampers the Formation of Neutrophil Extracellular Traps in Acute Mesenteric Ischemia-Reperfusion Injury

F. Bayer¹, S. Ascher¹, F. Sommer², C. Reinhardt¹
Abstract Number: OC 13.3

Combination of New Homozygous MPIG6B and SH2B3 Variants Leads to Early Onset Myelofibrosis, Thrombocytopenia and Abnormal Platelet Function

M.-C. Morel-Kopp^1,2, M. Levade¹, Q. Chen^1,2, A. Livings², J. Curtin³, Y. Zhu⁴, C. Ward^1,2, W. Stevenson^1,2
Abstract Number: PB0220

Combined Analysis of Dendritic Cell (DC) HLA-class-II (HLAcII) Peptidomic Profiling Data Derived from Different Therapeutic Factor VIII Proteins (tFVIIIs) in Independent Experiments/Laboratories

V.P. Diego^1,2, B.W. Luu^1,2,3, M. Hofmann⁴, M. Almeida^1,2, M.A. Gaytan^1,2, H. Mead⁵, J.S. Powell⁶, R. Rajalingam⁷, J.M. Peralta^1,2, S. Kumar^1,2, J.E. Curran^1,2, M.A. Escobar⁸, S. Williams-Blangero^1,2, E. Maraskovsky⁹, J. Blangero^1,2, T.E. Howard^2,3,10
Abstract Number: PB1191

Combined Factor Deficiencies Rare among the Rare Bleeding Disorders among Pediatric Population, Seven Years Experience in a Tertiary Care Center of Lahore, Pakistan

T. Fateen, N. Mazhar, N. Saqlain, N. Ahmed
Abstract Number: PB1106

Combined Gene and Cell Therapy for the Treatment of Hemophilia A within an Implantable Therapeutic Device

C. Olgasi¹, S. Merlin¹, C. Borsotti¹, A. Cucci¹, T. Bergmann², P. Bittorf², K. Patterson³, D.M. Mazzuca³, A. Stolzing⁴, M. Zierau⁵, P.M. Toleikis³, F. Benedicenti⁶, A. Calabria⁶, E. Montini⁶, J. Braspenning², A. Follenzi¹
Abstract Number: PB1597

Combined α4a- and β1-Tubulin Deficiencies Profoundly Affect Platelet Biogenesis and Haemostasis

Q. Kimmerlin¹, S. Moog¹, A. Yakusheva^1,2, A. Eckly¹, C. Gachet¹, P. Mangin¹, C. Strassel¹, F. Lanza¹
Abstract Number: PB0968

Comorbidities in Patients with Severe Haemophilia: Birth Cohort Analysis of Taiwan Society of Thrombosis and Hemostasis Database

J.-D. Wang^1,2, C.-Y. Lin², T.-F. Weng², S.-S. Chiou², C.-T. Peng², M.-C. Shen²
Abstract Number: PB1021

Comorbidities of Hemophilia & Factor XIII Deficiency Patients

M. Naderi¹, F. Malek²
Abstract Number: PB0324

Comparative Analysis of the Coagulometric and Chromogenic Methods for the Determination of Factor VIII Activity in the Plasma of Patients Suspected with Blood Coagulation Disorders

E. Wojtasinska, J. Rupa-Matysek, P. Dziatkiewicz-Warkocz, M. Kozlowska-Skrzypczak, L. Gil
Abstract Number: PB1208

Comparative Analysis of Three Custom Gene Panels Based on Next Generation Sequencing for Diagnostic of Inherited Coagulation Bleeding Disorders

N. Borràs¹, I. Corrales², L. Ramírez², N. Comes², F. Vidal³
Abstract Number: PB0563

Comparative Evaluation of the Aggregation Studies in a Sysmex CS2500 Coagulometer with a Standard Turbidimetric Technique

A. Ramos, M. Pino, P. Molina, A.B. Moreno Castaño, M. Díaz-Ricart, G. Escolar
Abstract Number: PB0319

Comparative Pharmacokinetics of Two Recombinant FVIII Concentrates in Chinese Pediatric Patients with Severe Hemophilia A: A Single-Center Study

K. Huang, R. Wu, Z. Chen, Y. Zhen, X. Wu, G. Li
Abstract Number: PB2268

Comparative Study between Thromboelastography and Conventional Coagulation Tests in Deep Vein Thrombosis

B. Yan, W. Du, T. Hu
Abstract Number: PB2506

Comparative Study of the Clinical Application of Two Bleeding Grading Systems for Pregnant Women with Immune Thrombocytopenia (ITP)

M.J. Huang, J. Huang, B. Zeng, P. Chen, R. Zhan
Abstract Number: PB0051

Comparison and Association of Fibrinogen, von Willibrand Factor and Factor VIII Levels with Risk of Cardiovascular Disease in Cigarette Smokers Residing in Calabar Metropolis, Nigeria

D.C. Okpokam¹, J.I. Asuquo², J.O. Akpotuzor¹
Abstract Number: PB1254

Comparison between Bleeding Time and PFA-200 to Evaluate Platelet Function Disorder in Children

C. Srichumpuang, D. Sosothikul
Abstract Number: PB0725

Comparison Natural History and Genotype of 31 Patients with Inherited Dysfibrinogenemia

T. Simurda¹, J. Zolkova¹, I. Skornova¹, M. Brunclikova¹, Z. Kolkova², D. Loderer², M. Dobrotova¹, J. Ivankova¹, M. Grendar², Z. Lasabova³, J. Stasko¹, P. Kubisz¹
Abstract Number: PB0289

Comparison of a New Point-of-Care Hemostasis Analyzer with Laboratory Parameters in Patients with Veno-venous Extracorporeal Membrane Oxygenation

M. Lejeune¹, P. Masi¹, C. Desnos¹, M. Pinton De Chambrun¹, J. Chommeloux¹, I. Martin-Toutain¹, G. Nguyen¹, A. Nieszkowska¹, N. Bréchot¹, M. Schmidt¹, C.-E. Luyt¹, I. Lefèvre², A. Combes¹, G. Hekimian¹, C. Frere^1,3
Abstract Number: PB0546

Comparison of a Novel Viscoelastic Device with Standard Laboratory Tests for its Clinical Validation in Peri-Operative Cardiac Patients

B. Brannan^1,2, P. Govender¹, S. Scheuermann¹, S. Macdonald², F. Falter³, M. Besser^2,3
Abstract Number: PB0165

Comparison of a Validated UHPLC-MS/MS Method and Chromogenic Anti-Xa Assays from Different Manufacturer for the Assessment of Edoxaban and its M4 Metabolite Levels in Plasma

R. Siriez¹, C. Bouvy², J.-M. Dogné^1,3, M. Hardy^4,5, P. Hainaut⁶, J. Laloy^3,7, F. Mullier⁴, H. Yildiz⁶, J. Douxfils^1,2
Abstract Number: PB1528

Comparison of an Automated von Willebrand Factor Activity Assay by HemosIL Werfen® with Ristocetin Cofactor Assay by Aggregometry in Thrombocytic Patients with Myeloproliferative Neoplasms or Secondary Thrombocytosis

P. Laporte¹, M. Tuffigo², A. Ryman¹, O. Mansier^1,3, M. Fiore¹, C. James^1,3
Abstract Number: PB0970

Comparison of Bleeding Pattern and Inhibitor Development among Hemophilia Patients: Prophylactic versus On-Demand Treatment

G. Wilfred, V. Selvaratnam, Y.Y. Yap, J. Sathar
Abstract Number: PB1148

Comparison of Bypassing Agents in Patients on Emicizumab Using Global Hemostasis Assays

H. Kizilocak¹, E. Marquez-Casas¹, J. Malvar¹, R. Carmona¹, G. Young^1,2
Abstract Number: PB1418

Comparison of Clinical Adverse Events during Empiric Therapy for Patients with Suspected HIT

K. Dykes¹, C. Johnson², J. Gong³, S.E. McKenzie⁴, H. Husseinzadeh⁴
Abstract Number: PB1118

Comparison of Coagulation Parameters Associated with Fibrinogen Concentrate and Cryoprecipitate for Treatment of Bleeding in Patients Undergoing Cytoreductive Surgery for Pseudomyxoma Peritonei: Results from the FORMA-05 Study

A. Roy¹, N. Sargant¹, C. Solomon², I. Kruzhkova², S. Knaub², F. Mohamed¹
Abstract Number: PB0637

Comparison of Different Stago Instruments for Fibrinogen Level Assessment with STA-liquid Fib

J.-B. Baudier¹, L. Chaillet², V. Genty², A. Carlo³, S. Langlet¹
Abstract Number: PB0898

Comparison of FVIII Prophylaxis Treatment Regimen and Associated Clinical Outcomes between rVIII-SingleChain and Other rFVIII Products Commonly Used in Italian Hemophilia A Patients

M.E. Mancuso¹, C. Santoro², G. Maro³, V. Rives⁴, P. Sommerer⁵
Abstract Number: PB0203

Comparison of Medication Adherence Between Different Oral Anticoagulants: A Propensity Weighted Nationwide Cohort Study

A.B. Ingason^1,2, J.P. Hreinsson³, A.S. Agustsson^1,2, S.H. Lund⁴, I.E. Reynisson⁵, B.R. Gudmundsdottir⁶, P.T. Onundarson^1,6, E.S. Bjornsson^1,2
Abstract Number: PB0543

Comparison of New Scoring System of Platelet Aggregation on Automated Coagulation Analyzer CN-6000 with CS-5100

M. Egashira¹, K. Kitano¹, R. Narisada², M. Kono³, K. Nakajima³, T. Sakayori¹
Abstract Number: PB1395

Comparison of Platelet Function Testing in Patients Undergoing Neuroradiological Flow Diversion Stents

M. Gergi¹, R. McTaggart², T. Cheves³, J. Sweeney⁴
Abstract Number: PB1798

Comparison of Platelet Parameters in the Patients with JAK2 V617F Mutated Essential Thrombocytosis and Reactive Thrombocytosis

Y. Wu^1,2, M. Gu³, S. Lin³, W. Huang¹, T. Wang^1,2, S. Chu^1,2
Abstract Number: OC 11.2

Comparison of Recommended Postpartum Thromboprophylaxis and of Absolute Risk Thresholds According to the RCOG, ACCP and ACOG Guidelines

N. Gassmann¹, M. Viviano², P. Fontana³, M. Righini³, B. Martinez De Tejada², M. Blondon³
Abstract Number: PB0520

Comparison of the Biophen® Heparin LRT with the HemosIL® Liquid Anti-Xa Assay for the Measurement of Apixaban, Edoxaban and Rivaroxaban

C. Bundschuh, M. Egger, K. Wiesinger, B. Dieplinger
Abstract Number: PB0594

Comparison of the One-Stage Clot-Based and Chromogenic Factor VIII Activity Measurement

R. Al Buraidi¹, M. Al-Khabori², K. Al Falahi², B. Al Baloushi², B. Al-Rawahi², J. Mahlangu³, A. Pathare²
Abstract Number: PB0576

Comparison of the T-TAS 01 PL Assay with PFA-100 for Assessment of Primary Hemostatic Function

J. Dahlen¹, P. Gurbel², A.H.B. Wu³, S.R. Lentz⁴, M. Fiore⁵, A. Leavitt³, K. Bliden², C.-M. Ong³, T. Peters⁴, U. Tantry², K. Hosokawa⁶
Abstract Number: PB0664

Comparison of Thromboelastography with T2MR Data

M. Stolz¹, M. Strauß², S. Hammer¹, I. Marini¹, F. Schick³, T. Bakchoul^1,2
Abstract Number: PB0698

Comparison of Thromboelastometry by ROTEM^® Delta and ROTEM^® Sigma in Obese Patients

C. Bulato¹, E. Campello¹, C.M. Radu^1,2, L. Spiezia¹, P. Simioni¹
Abstract Number: PB0560

Comparison of Two Quantitative Methods for Determination of Dabigatran Concentration: Diluted Thrombin Time Test and Innovance Dabigatran Test in Real Life Patients Treated with Dabigatran

S. Šupraha-Goreta¹, S. Margetić², I. Ćelap², R. Mihić³
Abstract Number: PB1364

Comparison of Various Diagnostic Methods in Assessing Platelet Count in Patients with Immunotrombocytopenia

M. Witkowski¹, M. Witkowska², M. Tybura-Sawicka³, A. Majchrzak¹, J. Treliński³, K. Chojnowski³, T. Robak⁴, P. Smolewski²
Abstract Number: PB0590

Comparison of Visual versus Reader Results of the Point of Care Test of Direct Oral Anticoagulants from Urine Samples

J. Harenberg¹, F. Loesel², J. Douxfils^3,4, I. Elalamy^5,6, J. Beyer Westendorf^7,8, R. Bauersachs⁹, P. Verhamme¹⁰, M. Crowther¹¹, S. Hetjens¹², C. Weiss¹²
Abstract Number: PB1580

Comparison of von Willebrand Factor (VWF) Multimeric Profile Obtained by a Commercial Electrophoretic Test (Hydragel 5 von Willebrand Multimers) and Classical Home-made with a Discontinuous 1% Agarose Gel Electrophoresis

M.S. López^1,2, J. Paiva³, A.I. Woods⁴, M.S. Saez^1,2, L.H. Barrera^1,5, V. Privitera⁶, F. Chuliber⁶, M. Villagra Iturre⁶, D. Penchasky⁶, P. Sorroche^1,2, J. Oyhamburu^1,2, M. Martinuzzo^1,2, A. Sánchez Luceros^3,4
Abstract Number: PB1783

Complement Mannan-Binding-Lectin Is Associated with Activated Platelets during Clot Formation in a Microfluidic Bleeding Model

M. Golomingi¹, L. Jenny¹, E.T. Hardy², W. Lam², V. Schroeder¹
Abstract Number: PB1945

Complement Pathway and Endothelial Dysfunction in Severe Preeclampsia

M. Palomo¹, M. Blasco², F. Crispi³, S. Torramade-Moix⁴, P. Molina⁴, J.M. Campistol², J.C. Garcia Pagan⁵, E. Gratacos³, G. Escolar⁴, M. Diaz-Ricart⁴
Abstract Number: OC 05.5

Complement Regulator Factor H is a Cofactor for Thrombin in both Pro- and Anticoagulant Roles

G. McCluskey¹, G. Davies¹, R. Velounias¹, T.R. Hughes², B.P. Morgan², R. Preston³, P.W. Collins^2,4, P.V. Jenkins⁴, M. Heurich¹
Abstract Number: PB1925

Complement Regulatory Abnormalities are Frequent in Patients with Catastrophic APS and Refractory Patients Respond Rapidly to Eculizumab Treatment

H. Liebman¹, I. Weitz²
Abstract Number: PB1470

Complex Changes in Plasma Associated with Platelet Dysfunction in Trauma Patients

A. St. John¹, J. Chen², J. Le², E. Lim¹, S. Stern¹, J. Lopez², N. White¹
Abstract Number: PB0450

Comprehensive Platelet Phenotyping Supports the Role of Platelets in the Pathogenesis of Acute Venous Thromboembolism – Results from Clinical Observational Studies

M. Panova-Noeva^1,2, B. Wagner³, M. Nagler³, V. ten Cate³, J. Prochaska^1,2,3, S. Heitmeier⁴, I. Meyer⁴, C. Gerdes⁴, V. Laux⁴, S. Konstantinides⁵, H. Spronk⁶, K. Lackner⁷, K. Leineweber⁴, H. ten Cate⁶, P. Wild^1,2,3
Abstract Number: PB2451

Concentration Levels of Direct Oral Anticoagulants and Clinical Relevance in a Tertiary Hospital

F. Martins Pereira¹, I. Machado², A.P. Teixeira², L. Ricca Gonçalves², M. Carvalho², C. Koch²
Abstract Number: PB0819

Concizumab Does Not Affect Activated Partial Thromboplastin Time, Prothrombin Time or Factor VIII/IX Activity Measured Using One-Stage Clotting or Chromogenic Substrate Assays

M. Kjalke, M. Kjelgaard-Hansen, I. Hilden
Abstract Number: PB2085

Concomitant Use of Direct Oral Anticoagulants and Antiepileptic Drugs: A Prospective Cohort Study in Patients with Atrial Fibrillation

M. Giustozzi¹, M. Mazzetti², M. Paciaroni¹, G. Agnelli¹, C. Becattini¹, M.C. Vedovati¹
Abstract Number: PB1198

Congenital Afibrinogenemia. Report of a Case in the Children´S Hospital of Mexico Federico Gomez

J.F. Mariano González¹, A.M. Moreno González²
Abstract Number: PB1190

Congenital Combined Bleeding Disorders, a Study on a Large Number of Iranian Patients

M.R. Baghaipour¹, S. Tabibian^1,2, F. Ala¹, M. Jazebi¹, G.R. Bahoush^1,3, S.E. Ahmadi², N. Baghaipour⁴
Abstract Number: PB0190

Congenital Factor X Deficiency with Isolated Prothrombin Time Prolongation

D. Gurlek Gokcebay¹, D. Kacar¹, S. Sahin¹, N. Yarali¹, N.Y. Ozbek¹, A. Girolami²
Abstract Number: PB0719

Congenital Qualitative Fibrinogen Disorders: Case Series from Argentina; Multicentric Collaborative Study

C.M. Rosa¹, M. Neerman-Arbez², C. Duboscq³, A. Vilaseca⁴, J. Ceresetto³, M.E. Aris Cancela⁵, P. Colimodio⁵, L. Barrera^6,7, M.S. Lopez^6,7, J.M. Oyhamburu^6,7, V. Privitera⁸, E.S. Viñuales⁸, E. Nucifora⁸, M. Kalmus⁸, S. Meschengieser⁹, A. Casini¹⁰, P. de Moerloose¹¹, M.E. Martinuzzo^7,12
Abstract Number: PB1092

Consistent Structural Kinetics of Valoctocogene Roxaparvovec DNA in Human Blood Samples

C. Russell¹, R. Torres¹, K. Patton¹, J. Holcomb¹, M. Vora¹, K. Obrochta¹, A. van Tuyl¹, B. Kim², S. Zoog¹, C. Vettermann¹
Abstract Number: PB1117

Continuous Infusion with Kovaltry (Octocog Alfa) during Cardiac Surgery for Tetralogy of Fallot in an Hemophilic Child

A. Amoruso, G. Lassandro, V.V. Palmieri, V. Palladino, C. Pastore, P. Giordano
Abstract Number: PB1933

Contribution of Beta2 Glycoprotein1 IgA (B2GP1 IgA) Antibodies Research in Diagnosis of Seronegative Antiphospholipid Syndrome in Cerebral Thrombosis: A Case Series of 21 Patients

I. Hocine, Y. Ferhat-Hamida, G. Hariti
Abstract Number: PB0007

Contribution of Fibrin and von Willebrand Factor to Platelet Adhesion on Ruptured Atherosclerotic Plaque in Acute Myocardial Infarction

A. Yamashita¹, K. Nishihira², K. Maekawa¹, T. Gi¹, S. Horiuchi¹, K. Hatakeyama³, Y. Shibata², Y. Asada¹
Abstract Number: PB0815

Contributions of the Individual Components of an Activated Prothrombin Complex Concentrate to Thrombin Generation in the Presence of Emicizumab

D. Monroe¹, M. Ezban², M. Hoffman^3,4
Abstract Number: PB2165

Cooperation about the Treatment of the Venous Thromboembolism in Cancer Institute Hospitals and Neighboring Cooperation Acute Hospitals

C. Yasuda¹, T. Shiga², K. Iwasa³, M. Shoji³, T. Takahashi⁴, Y. Nishihata⁵, K. Suzuki⁴
Abstract Number: PB0266

Corn Trypsin Inhibitor in the Preanalytical Phase of Contact Activation Assays

M.M. Engelen^1,2, C. Vandenbriele^1,2, P. Verhamme^1,2, T. Vanassche^1,2
Abstract Number: PB1143

Correction of Human Hemophilia B Gene in iPSCs by Base-Editing Approach Based on Engineered Cas9 with Broad PAM Flexibility

T. Hiramoto¹, Y. Kashiwakura¹, T. Abe², N. Kamoshita¹, M. Hayakawa¹, H. Inaba³, T. Togashi¹, H. Nishimasu⁴, Y. Hanazono², O. Nureki⁴, T. Ohmori¹
Abstract Number: PB0399

Correlation between ADAMTS13 and VAP1 Levels in Multiple Sclerosis with Cerebral Microbleeds

N. Ziliotto¹, R. Zivadinov^2,3, M. Baroni¹, D. Jakimovski², N. Bergsland^2,4, D.P. Ramasamy², B. Weinstock-Guttman⁵, M. Ramanathan⁶, G. Marchetti⁷, F. Bernardi¹
Abstract Number: PB2475

Correlation between Anti-Xa Activity and Plasmatic Levels of Apixaban

D. Velasco¹, R. Vidal², A. Garcia Raso³, S. Martin³, P. Llamas³
Abstract Number: PB0617

Correlation between INR Pocket Test and Standard Coagulation Test

A.B. Vilaseca¹, N.M. Mato¹, R.F. Barbera², G. Begue¹, C. Capmany¹, N. Kujta¹, E.M. Romero¹, P. Sebastian¹, C.C. D´antonio¹
Abstract Number: PB2326

Correlation between Intrinsic D-Dimer Levels and D-Dimer Measured at First Venous Thromboembolism (VTE)

F.B. Rinde¹, E.-S. Hansen¹, V. Morelli¹, J.-B. Hansen^1,2, S.K. Brækkan^1,2
Abstract Number: PB1884

Correlation between Phenotype-genotype versus in-silico Prediction of Novel and Known Disease-causing Variants in Upshaw-Schulman Syndrome Patients in a Single Institution of Argentina

J. Paiva¹, A.I. Woods², A. Kinen¹, M.M. Casinelli¹, A. Sanchez-Luceros^1,2
Abstract Number: PB0384

Correlation between Protein C and CCL18 Levels in Multiple Sclerosis

N. Ziliotto¹, R. Zivadinov^2,3, M. Baroni¹, D. Jakimovski², N. Bergsland^2,4, D.P. Ramasamy², B. Weinstock-Guttman⁵, M. Ramanathan⁶, G. Marchetti⁷, F. Bernardi¹
Abstract Number: PB0540

Correlation between the VerifyNow P2Y12 Assay and the Newly-Developed APAL System in Neuroendovascular Patients

K. Uematsu^1,2, T. Sakayori³, H. Ishida⁴, Y. Omori⁴, K. Kitano³, H. Matsubara², Y. Enomoto²
Abstract Number: PB0578

Correlation between Thrombin Generation and Prothrombin Fragment F1+2 Plasma Levels

M. Capecchi^1,2, E. Scalambrino¹, S. Griffini¹, E. Grovetti^1,3, M. Clerici¹, G. Merati¹, V. Chantarangkul^1,3, M. Cugno^1,3,4, F. Peyvandi^1,3,4, A. Tripodi^1,3
Abstract Number: PB1498

Correlation GLATIT Scores and the Number of Bleeding Episodes in the Assessment of the Prognosis of Inherited Platelet Disorder

R. Messaoudi, D.Saidi, H.Touhami
Abstract Number: PB0003

Correlation of D-Dimer Levels with Troponin I in Patients with Acute Myocardial Infarction

M. Ismail
Abstract Number: PB2473

Correlation of Reperfusion Therapy and In-hospital Mortality in Patients with Intermediate Risk Acute Pulmonary Embolism and Right Ventricular Dysfunction

J. Bilbao¹, J. Bonorino¹, F. Horacio¹, C. Ferrario², N. Torres¹, M. Iwanowski¹, R. Melchiori¹, P. Alarcon¹, J. Santucci¹, M. Conde Blanco², E. Ortis¹, M.E. Aris Cancela³, R. Della Cella¹, S. Krause¹, A. Sanchez¹, N. Perez Caceres¹, S. Marquez¹, P. Rubio¹, A. Hita¹, S. Baratta¹
Abstract Number: PB1406

Correlation of VASP Phosphorylation Assay with Light Transmission Aggregometry for Patients Treated with Clopidogrel or Ticagrelor

C. Pons¹, M. Moulard¹, M. Canault², M. Ibrahim², M.-C. Alessi²
Abstract Number: PB1048

Correlations of Von Willebrand Factor Levels, Factor VIII (FVIII) Pharmacokinetics and Prophylaxis Dose in Severe Haemophilia A Patients Switching to rFVIII-Fc Studied by Individual and Population Tool-assisted PK Assessments

A. Coppola¹, G. Quintavalle¹, G.F. Rivolta¹, F. Riccardi¹, A. Matichecchia¹, A. Benegiamo², R.D. Ruenes², F.L. Dallari², R. Rossi², A. Tagliaferri¹
Abstract Number: PB1378

Corticosteroid Reduction or Discontinuation after Initiation of Avatrombopag Treatment in Patients with Chronic Immune Thrombocytopenia (ITP)

M. Recht^1,2, A. Dixon³, K. Aggarwal³, M. Vredenburg³
Abstract Number: PB2284

Cost-Effectiveness of Magnetic Resonance Direct Thrombus Imaging for Diagnosing Recurrent Ipsilateral Deep Vein Thrombosis

L.F. van Dam¹, W.B. van den Hout², G. Gautam³, C.E.A. Dronkers^1,4, Å. Eckerbom³, W. Ghanima^5,6, J. Gleditsch⁷, A. von Heijne³, H.M.A. Hofstee⁴, M.M.C. Hovens⁸, M.V. Huisman¹, A.T.A. Mairuhu⁹, M. Nijkeuter¹⁰, M.A. van de Ree¹¹, C.J. van Rooden¹², R.E. Westerbeek¹³, J. Westerink¹⁰, E. Westerlund³, L.J.M. Kroft¹⁴, F.A. Klok¹
Abstract Number: PB0768

Covalent Prourokinase-dendrimer Complexes with Increased Plasma Stability and High Thrombolytic Activity in vitro

E. Ivanova¹, L. Mukhametova^1,2, R. Aisina¹, K. Gershkovich³
Abstract Number: PB/CO21

COVID-19 Pandemic: Dissecting Coagulation apart from Inflammation

J. Gonzalez-Lugo¹, S. Rahman¹, M. Barouqa², J. Szymanski², H. Billett¹, M. Reyes Gil²
Abstract Number: PB0141

CRISPR/Cas9-Mediated Generation of a RUNX1 Knock-In Mice Model and Platelet Characterization

A. Marín-Quílez¹, R. Benito¹, I. García-Tuñón¹, C. Fernández-Infante¹, L. Hernández-Cano¹, A. Vega-Marín¹, L. Méndez-Sánchez², M. del Rey¹, J.L. Ordoñez¹, V. Palma-Barqueros³, M.L. Lozano³, M. Sánchez-Martín^1,2, C. Guerrero¹, J.R. González Porras⁴, J. Rivera³, J.M. Hernández-Rivas^1,4, J.M. Bastida⁴
Abstract Number: PB1844

Critical Role for Platelet Ral GTPases in the Regulation of Venous Thrombosis

Y. Li, C. Williams, B. Amulic, A. Poole
Abstract Number: PB1843

Critical Role of Platelets during Pulmonary Fibrosis

R. Martos¹, I. Machkour¹, R. Chalghoumi¹, K. Yahiaoui¹, H. Lebas¹, W. Bergemeier², B. Nieswandt³, V. Arocas¹, M.-C. Bouton¹, Y. Boulaftali¹
Abstract Number: PB0470

Cross-sectional Study of Thrombin Generation and Overall Hemostatic Potential in a Cohort Clinically Investigated for Thrombophilia

M. Farm^1,2, D.E. Schmidt^3,4, Y. Zong¹, N. Soutari^1,2, A. Antovic^5,6, I. Pruner¹, J.P. Antovic^1,2, N. Bark²
Abstract Number: PB1768

Cross-Talk of Activated Protein C(aPC) with Integrin and its Effect on T-Cell Signaling

D. Gupta¹, S. Ranjan¹, A. Elwakiel¹, A. Müller², R. Rana¹, S. Kohli¹, B. Isermann¹
Abstract Number: PB0056

Crosstalk between Platelet and Endothelial Dysfunction in Survivors of Allogeneic Hematopoietic Cell Transplantation Independently of Traditional Cardiovascular Risk Assessment

E. Gavriilaki^1,2, E. Gkaliagkousi², I. Sakellari¹, I. Batsis¹, A. Vardi¹, A. Lazaridis², P. Anyfanti², B. Nikolaidou¹, I. Zarifis², M. Masmanidou¹, E. Yiannaki³, D. Markala³, S. Douma², A. Anagnostopoulos¹
Abstract Number: PB1953

CTL-2 is a VWF Receptor Involved in Neutrophil Activation

G. Zirka¹, P. Robert^2,3, J. Tilburg⁴, C. Maracle⁴, P. Legendre⁵, M.C. Alessi^1,6, P.J. Lenting⁵, P.E. Morange^1,7, G.M. Thomas¹
Abstract Number: PB0912

Current Challenges in Diagnosis and Management of Hemophilia Afghanistan

S.H. Mousavi^1,2, S.A. Mesbah-Namin³, M. Jazebi⁴, A. Dorgalaeh⁵, S. Zeinali^6,7
Abstract Number: PB1513

Current Data About Arterial Thrombotic Events in Cerebrovascular Circulation Caused by Sticky Platelet Syndrome in the National Registry of Thrombophilic States in Slovak Republic

M. Brunclikova¹, L. Stanciakova², J. Ivankova², M. Skerenova³, M. Dobrotova², P. Holly², T. Simurda², P. Kubisz², J. Stasko²
Abstract Number: PB1864

Current Possibilities of ADAMTS 13 Diagnostics – Advantages and Limitations

P. Bradacova¹, L. Slavik², J. Ulehlova², J. Prochazkova², A. Hlusi², K. Chasakova³
Abstract Number: PB2135

Current Status on Non-hematological Cancer Associated Thrombosis at Tertiary Care Hospital in India

M. Aggarwal¹, A. Ramaswami^2,3, M. Mahapatra²
Abstract Number: PB2007

Cytokine Network Architecture at the Endothelial Interface

A.J. Hoogendijk¹, E.F.J. Janssen¹, B.L. van den Eshof¹, F.P.J. van Alphen¹, C. van der Zwaan¹, A.B. Meijer^1,2, M. van den Biggelaar¹