ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB0159

G-Quadruplex Related Aptamers to Thrombin Exosite I with Additional Duplex Region. Relationships between their Structure, Stability and Antihtrombin Activity

A. Mazurov¹, V. Spiridonova², T. Novikova², V. Sizov², V. Shashkovskaya², E. Zharikova¹, E. Titaeva¹, A. Dobrovolsky¹
Abstract Number: PB1572

Gastrointestinal Bleeding from Angiodysplasia in Constitutional von Willebrand Disease: Improved Diagnosis Yield and Risk Stratification when Using Video Capsule on Top of Conventional Endoscopy

A. Rauch^1,2, C. Paris¹, Y. Repesse³, J. Branche⁴, R. Gerard⁴, R. D'Oiron⁵, A. Harroche⁶, C. Ternisien⁷, S. Castet⁸, A. Lebreton⁹, B. Pan-Petesch¹⁰, F. Volot¹¹, S. Clayssens¹², P. Chamouni¹³, V. Gay¹⁴, A. Veyradier¹⁵, J. Goudemand¹, S. Susen^1,2
Abstract Number: PB0065

Gender-Associated Cardiometabolic Biomarkers in Young Adults

V. Chulkov¹, N. Vereina¹, V. Chulkov¹, S. Sinitsin¹, V. Sumerkina¹, E. Lenets¹, O. Tarasova¹, E. Gavrilova²
Abstract Number: PB0491

Gene Therapy Model by Modification of F9 Gene through CRISPR/Cas9 for Functional Factor IX Production in Mesenchymal Stem Cells: Preliminary Results

I.J. Lara Navarro^1,2, L.F. Jave Suarez³, J.A. Marchal Corrales⁴, R. Ramírez Solís⁵, A.R. Jaloma Cruz²
Abstract Number: PB0425

Gene-Gene Interactions of Folate Cyclein as a Potential Factor of the Risk of Thrombosses in Patients with Breast Cancer

A. Markovsky
Abstract Number: PB1968

Generation and Isolation of Extracellular Vesicles from Endothelial and Smooth Muscle Cells Grown out of Human Blood

P. Ferreira, N. Kirkby, J. Mitchell, B. Ahmetaj-Shala
Abstract Number: PB1801

Generation of 12-HETE in Platelet-Cancer Cell Crosstalk

M. Dovizio, S. Schiavone, S. Tacconelli, R. Fullone, R. Grande, M. Zucchelli, M. Marchisio, P. Lanuti, P. Ballerini, P. Patrignani
Abstract Number: PB1608

Generation of Megakaryocytes from Human Bone Marrow Aspirates as a Simple Diagnostic and Research Tool: Assay Development and Validation

K. Butov^1,2, N. Mikhalkin², R. Nikolaev³, A. Volkova⁴, E. Osipova¹, K. Machlus⁵, M. Panteleev^1,2
Abstract Number: OC 13.2

Genetic Analyses in 391 VWD Patients: Novel VWF Gene Variations, and Important Differences in the Phenotype of Type 1 VWD Patients with- and without – a VWF Gene Mutation

F. Atiq¹, W.L. van Heerde², J. Boender¹, M.H. Cnossen³, B.A.P. Laros-van Gorkom², J. de Meris⁴, K. Fijnvandraat^5,6, S. Schoormans², J.G. van der Bom^7,8, K. Meijer⁹, K.P.M. van Galen¹⁰, J. Eikenboom^11,12, F.W.G. Leebeek¹, WiN Study Group
Abstract Number: PB0621

Genetic Analysis for Investigation of Heritable Bleeding and Thrombotic Disorders – Variable Interpretation of Data Identified by the UK National External Quality Assessment Scheme (UK NEQAS) Blood Coagulation Programme

I. Jennings¹, M. Hill², M. Sutherland³, C. Millar⁴, A. Page⁵, R. Wheeler⁶, I. Walker¹, S. Kitchen¹, A. Goodeve⁷
Abstract Number: PB1496

Genetic Characterization of Inherited Platelet Disorders in a Single Portuguese Center for Coagulopathies

S. Morais¹, C. Lau¹, C. Monteiro¹, M. Pereira¹, M. Gonçalves¹, A. Gonçalves², J. Oliveira², E. Cruz¹, R. Santos², M. Lima¹
Abstract Number: OC 08.3

Genetic Dissection of Structural Variants in the Largest Cohort of Patients with Antithrombin Deficiency and Characterisation of the First Complex Structural Variant in SERPINC1 by Long-read Whole Genome Sequencing

B. de la Morena-Barrio¹, J. Padilla², A. Sanchis-Juan^3,4, M.E. de la Morena-Barrio², J.L. García⁵, J. Stephens^3,4, N. Borràs⁶, A. Miñano², R. Cifuentes², C. Bravo-Pérez², F. Vidal⁶, J.M. Hernandez-Rivas⁵, W. Ouwehand^3,4, V. Vicente², J. Corral²
Abstract Number: PB2182

Genetic Study for Idiopathic Venous Thromboembolism in Japanese Using Short-Read and Long Read Sequencers: A Pilot Study of Japanese Group of Idiopathic Thromboembolism

A. Tsuji¹, A. Sekine², H. Wada³, E. Morishita⁴, Y. Ogihara⁵, K. Nogami⁶, T. Kojima⁷, T. Matsushita⁸, N. Yamada⁹, T. Ogo¹, R. Neki², K. Kokame², S. Yasuda¹, T. Miyata²
Abstract Number: PB1874

Genetic Study of von Willebrand Factor Variants in Congenital Thrombotic Thrombocytopenic Purpura Patients

C. Lupo¹, C. Vendramin¹, F. Alwan², M. Scully^1,2
Abstract Number: PB1890

Genetic Variants in ADAMTS13 in Patients with Acquired TTP (aTTP)

J. Paiva¹, A.I. Woods², A. Kinen¹, M.M. Casinelli¹, A. Sanchez-Luceros^1,2
Abstract Number: PB1205

Genotype and Phenotype Characterization in RBDs: A Spanish Pilot Study

B. Rey Búa¹, N. Bermejo², J.M. Calvo³, M. Martín-Salces⁴, A. Rodríguez Alen⁵, J. Dávila⁶, M. Pérez Sánchez⁷, J.M. Martín Antoran⁸, C. García Díaz⁹, R. Benito¹⁰, M. Del Rey¹⁰, J.M. Hernández-Rivas^1,10, J.R. González-Porras¹, J.M. Bastida¹
Abstract Number: PB1439

Genotypic Analysis at Transition from Idiopatic Thrombocytopenic Purpura to Inherited Trombocytopenia

C. Albayrak¹, D. Albayrak², H. Gürkan³
Abstract Number: PB1493

Glanzmann Thrombasthenia in Pakistani Patients: Biochemical Analyses & Identification of Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3

M.Y.J. Siddiqi¹, D. Boeckelmann², A. Naz¹, S. Ahmed¹, A. Najmuddin³, A. Imran⁴, B. Zieger², T.S. Shamsi¹
Abstract Number: PB1509

Glanzmann Thrombasthenia-like Syndrome: Report of 2 Cases

K. Mendi^1,2, M. Dahmane^1,2, V. Jallu³, R. Petermann³
Abstract Number: PB1359

Glibenclamide-Induced Thrombocytopenia: A Case Reort

Y. Cherif, M. Mrouki, S. Derbel, F. Ben Dahmen, M. Abdallah
Abstract Number: PB0783

Global Coagulation Analysis for Acquired Hemophilia A Patients with the Marked Elevation of Factor VIII Activity during Remission Phase

M. Takeyama¹, K. Nogami¹, F. Shibasaki², K. Sasai¹, M. Shima¹
Abstract Number: PB0431

Global Coagulation Assays in Patients with Chronic Kidney Disease

H.Y. Lim^1,2,3, B. Lui¹, D. Barit¹, H. Nandurkar², P. Ho¹
Abstract Number: PB1306

Global Hemostasis, Procoagulation and Anticoagulation Proteins Derangements in Children and Adolescents with Hemoglobin H and Beta-Thalassemia/Hemoglobin E Diseases

R. Natesirinilkul¹, C. Choedamphai¹, P. Charoenkwan¹, L. Sathitsamitphong¹, S. Manowong¹, K. Fanhchaksai², N. Tachawong¹
Abstract Number: PB1504

Global Tests of Primary Hemostasis for the Diagnosis of Mild/Moderate Bleeding Disorders (MMBD): Rehabilitating the Skin Bleeding Time

A. Baccolo, E. Falcinelli, A.M. Mezzasoma, P. Gresele
Abstract Number: PB0579

Global Thromboelastometry in Patients with Acute Bleedings on Direct Oral Anticoagulant (DOA) Treatment: The RO-DOA Bleed Study

M.C. Vedovati, M.G. Mosconi, F. Isidori, G. Agnelli, C. Becattini
Abstract Number: PB1329

Glucocorticoid Receptor Modulates the Mitochondria Function of Myeloid-Derived Suppressor Cells in Immune Thrombocytopenia

S. Wang, J. Xie, Q. Feng, J. Peng
Abstract Number: PB1681

Glycans on the Surface of Platelet Microparticles Mediate Binding by Hepatocytes

D.E. van der Wal¹, L.M. Rey Gomez¹, D.C. Marks^1,2
Abstract Number: PB1134

Glycocalyx Shedding as a Potential Driver of Trauma-induced Coagulopathy in Severe Trauma Patients: Insights from the TRAUCC Trial

M. Desvages^1,2, F. Lassalle^1,2, D. Garrigue^3,4, F. Machuron⁵, A. Duhamel⁵, M. Didelot², B. Vaast^1,2, A. Rauch^1,2, A. Hochart¹, B. Bijok^3,4, A. Godier^6,7, S. Susen^1,2
Abstract Number: PB1520

Golgi SNARE STX5 Regulates Golgi Morphology and WPB Biogenesis

E. Karampini¹, J. Olins¹, A. Mulder², F. van Alphen¹, D. Geerts³, C. Jost², M. van den Biggelaar¹, J. Voorberg^1,4, R. Bierings^1,5
Abstract Number: OC 04.2

GPR56 is a Platelet Collagen-Responsive GPCR and Hemostatic Sensor of Shear Force

J. Yeung, R. Adili, E. Stringham, A. Vizurraga, L. Roselli, M. Yu, M. Holinstat, G. Tall
Abstract Number: PB0369

Granulocyte Microvesicles with a High Plasmin Generation Capacity Promote Clot Lysis and Improve Outcome in Septic Shock

S. Cointe^1,2, L. Vallier¹, M. Dacos¹, A. Bonnyfay¹, N. Macagno³, K. Harti Souab⁴, C. Chareyre¹, C. Judicone⁵, D. Frankel⁶, S. Hraiech⁷, M.-C. Alessi¹, P. Poncelet⁵, J. Albanese⁴, F. Dignat-George^1,2, R. Lacroix^1,2
Abstract Number: PB1595

Gum Bleeding in Low Von Willebrand Factor- What’s the Score?

A. Dougall^1,2, L. Parkinson³, S. Anishchuk¹, M. Nolan², K. Ryan², N. O'Connell², M. Lavin⁴, J. O'Donnell⁴, B. Daly¹
Abstract Number: PB1516

Gynaecological Outcomes in Women with Inherited Platelet Function Disorders: Preliminary Data from the ISTH REDCap Registry

D. Obeng-Tuudah^1,2,3, A. Epstein², I. Ben Amor⁴, W. Thomas⁵, M. El Ekiaby⁶, T. Nwagha⁷, N. Hossain⁸, M.Z. Núñez Payamps⁹, G. Castaman¹⁰, A. Mumford¹¹, K. Gomez^1,2, R.A. Kadir^1,2,3
Abstract Number: PB1581

Gynaecological Problems, Management and Outcomes in Women with Moderate and Severe von Willebrand Disease (VWD)

O. Turan, A. Epstein, D. Pollard, R. Abdul-Kadir

ISTH 2020 Congress

G-Quadruplex Related Aptamers to Thrombin Exosite I with Additional Duplex Region. Relationships between their Structure, Stability and Antihtrombin Activity

Gastrointestinal Bleeding from Angiodysplasia in Constitutional von Willebrand Disease: Improved Diagnosis Yield and Risk Stratification when Using Video Capsule on Top of Conventional Endoscopy

Gender-Associated Cardiometabolic Biomarkers in Young Adults

Gene Therapy Model by Modification of F9 Gene through CRISPR/Cas9 for Functional Factor IX Production in Mesenchymal Stem Cells: Preliminary Results

Gene-Gene Interactions of Folate Cyclein as a Potential Factor of the Risk of Thrombosses in Patients with Breast Cancer

Generation and Isolation of Extracellular Vesicles from Endothelial and Smooth Muscle Cells Grown out of Human Blood

Generation of 12-HETE in Platelet-Cancer Cell Crosstalk

Generation of Megakaryocytes from Human Bone Marrow Aspirates as a Simple Diagnostic and Research Tool: Assay Development and Validation

Genetic Analyses in 391 VWD Patients: Novel VWF Gene Variations, and Important Differences in the Phenotype of Type 1 VWD Patients with- and without – a VWF Gene Mutation

Genetic Analysis for Investigation of Heritable Bleeding and Thrombotic Disorders – Variable Interpretation of Data Identified by the UK National External Quality Assessment Scheme (UK NEQAS) Blood Coagulation Programme

Genetic Characterization of Inherited Platelet Disorders in a Single Portuguese Center for Coagulopathies

Genetic Dissection of Structural Variants in the Largest Cohort of Patients with Antithrombin Deficiency and Characterisation of the First Complex Structural Variant in SERPINC1 by Long-read Whole Genome Sequencing

Genetic Study for Idiopathic Venous Thromboembolism in Japanese Using Short-Read and Long Read Sequencers: A Pilot Study of Japanese Group of Idiopathic Thromboembolism

Genetic Study of von Willebrand Factor Variants in Congenital Thrombotic Thrombocytopenic Purpura Patients

Genetic Variants in ADAMTS13 in Patients with Acquired TTP (aTTP)

Genotype and Phenotype Characterization in RBDs: A Spanish Pilot Study

Genotypic Analysis at Transition from Idiopatic Thrombocytopenic Purpura to Inherited Trombocytopenia

Glanzmann Thrombasthenia in Pakistani Patients: Biochemical Analyses & Identification of Novel Pathogenic Variants in the Fibrinogen Receptor αIIbβ3

Glanzmann Thrombasthenia-like Syndrome: Report of 2 Cases

Glibenclamide-Induced Thrombocytopenia: A Case Reort

Global Coagulation Analysis for Acquired Hemophilia A Patients with the Marked Elevation of Factor VIII Activity during Remission Phase

Global Coagulation Assays in Patients with Chronic Kidney Disease

Global Hemostasis, Procoagulation and Anticoagulation Proteins Derangements in Children and Adolescents with Hemoglobin H and Beta-Thalassemia/Hemoglobin E Diseases

Global Tests of Primary Hemostasis for the Diagnosis of Mild/Moderate Bleeding Disorders (MMBD): Rehabilitating the Skin Bleeding Time

Global Thromboelastometry in Patients with Acute Bleedings on Direct Oral Anticoagulant (DOA) Treatment: The RO-DOA Bleed Study

Glucocorticoid Receptor Modulates the Mitochondria Function of Myeloid-Derived Suppressor Cells in Immune Thrombocytopenia

Glycans on the Surface of Platelet Microparticles Mediate Binding by Hepatocytes

Glycocalyx Shedding as a Potential Driver of Trauma-induced Coagulopathy in Severe Trauma Patients: Insights from the TRAUCC Trial

Golgi SNARE STX5 Regulates Golgi Morphology and WPB Biogenesis

GPR56 is a Platelet Collagen-Responsive GPCR and Hemostatic Sensor of Shear Force

Granulocyte Microvesicles with a High Plasmin Generation Capacity Promote Clot Lysis and Improve Outcome in Septic Shock

Gum Bleeding in Low Von Willebrand Factor- What’s the Score?

Gynaecological Outcomes in Women with Inherited Platelet Function Disorders: Preliminary Data from the ISTH REDCap Registry

Gynaecological Problems, Management and Outcomes in Women with Moderate and Severe von Willebrand Disease (VWD)