ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1121

Idarucizumab to Neutralize Dabigatran in a University Hospital: The Relevance of Renal Function

A. Fattorini¹, L. Pozzi², L. Tomassini¹, L. Crippa¹, P. Della Valle¹, A. D'Angelo¹
Abstract Number: PB1467

Idelalisib Selectively Inhibits GPVI-mediated Platelet Activation and Shows Anti-atherothrombotic Activity

M. Nuñez Barrachina¹, I. Izquierdo¹, L. Hermida-Nogueira¹, L. A. Morán¹, A. B. Arroyo², N. García-Barberá², R. González-Conejero², J. Rivera², C. Martínez², M. I. Loza³, E. Domínguez³, Á. García¹
Abstract Number: PB1452

Identification and Functional Study of a New Germline Variant in Mecom Gene

N. Papa¹, A. Marzollo², M. Faleschini³, T. Giangregorio³, M. Dall'Arche⁴, M. Gabelli^2,5, C. Tretti², A. Biffi², S. Bresolin², A. Savoia^1,3
Abstract Number: PB0464

Identification of a Circulating Lipid Profile Associated with Venous Thromboembolism

A. Fernandez-Pardo¹, J. Oto¹, M. Alcoriza², L. Martos¹, E. Plana³, M.J. Solmoirago¹, M. Yelo¹, F. Cana¹, F. Ferrando⁴, A. Blanquer⁴, S. Bonanad⁴, F. España¹, P. Medina¹, M. Roca⁵, S. Navarro¹
Abstract Number: PB/CO04

Identification of a COVID-19 Subpopulation Responsive to Hydroxychloroquine Using Machine Learning: The IDENTIFY Trial

C. Lam, S. Mataraso, A. Lynn-Palevsky, A. Green-Saxena, G. Barnes, J. Hoffman, J. Calvert, E. Pellegrini, R. Das
Abstract Number: PB0321

Identification of a Novel “Laminin G” Domain Mutant of Protein S Defective in Binding and Inhibiting FIXa and Unaffected in APC/TFPI Cofactor Activities

S. Chatterjee, V. Pilli, R. Majumder
Abstract Number: PB1506

Identification of a Novel Molecular Variant in the PTGS1 Gene that Causes a Loss of a Glycan in the Catalytic Domain, Defects in Platelet Thromboxane A2 Synthesis, and Bleeding

V. Palma-Barqueros¹, M. Crescente², M. Chan², M.E. de la Morena-Barrio³, J.M. Bastida⁴, N. Bohdan³, E. Almarza⁵, S. Suarez-Varela⁶, I. Casas-Aviles⁶, J. Padilla³, A. Rodriguez-Alen⁷, A. Marin-Quilez⁴, N. Revilla³, V. Vicente³, J. Corral³, M.L. Edin⁸, D. Zelding⁸, M.L. Lozano³, T. Warner², J. Rivera³
Abstract Number: PB0194

Identification of Key Residues in Protein Z Dependent Protease Inhibitor (ZPI) for Efficient Protease Inhibiton

T. Sengupta¹, C.G. Subash², S. Gupta²
Abstract Number: PB1914

Identification of microRNAs Potentially Involved in Primary Antiphospholipid Syndrome Related Thrombosis

C. Oliveira Vaz¹, M. Vieira Geraldo¹, L. Ferreira Alves¹, P.E. Nascimento Silva Vasconcelos¹, M. Aparecida Cursino¹, J. Coelho França Quintanilha¹, L. Brito Bastos¹, G.L. Tripiquia Vechiatto Mesquita¹, B. Cardoso Jacintho¹, A.P. Rosa dos Santos¹, N. Godoy Torso¹, J. Marques de Oliveira², T. Sereno Cobaxo¹, A. Aparecido Geraldo¹, J. Bassani Borges³, R.C. Costa de Freitas³, J.M. Annichino-Bizzacchi¹, B. Moraes Mazetto¹, P. Moriel¹, F. Loureiro de Andrade Orsi¹
Abstract Number: PB0831

Identification of Novel Genetic Risk Factors in the Conserved Haplotype Region Surrounding the LCT Locus on Chromosome 2q21

A. Cairo¹, E. Pappalardo², S. Spena², M. Mancuso¹, F. Peyvandi^1,2
Abstract Number: PB0174

Identification of Novel Proteins Binding to Coagulation Factor XIII Free B-Subunit

B. Li, V. Schroeder
Abstract Number: PB2278

Identification of Somatic Mutations Associated with Clonal Hematopoiesis in Unprovoked Venous Thromboembolism

Á. Fidalgo-Fernández¹, M. Hernández-Sánchez², A. Marín-Quílez², R. Benito², S. Santos-Mínguez², C. Miguel-Gracía², I. Rodríguez-Iglesias², S. González-Briones², M. García-García¹, M. Quijada-Álamo², A. Hortal³, S. Cadenas Menéndez¹, J.R. González Porras¹, J.M. Hernández-Rivas^1,2, J.M. Bastida¹
Abstract Number: PB0258

Identification of the Histidine-rich Glycoprotein Domain Responsible for Contact Pathway Inhibition

T.K. Truong^1,2, R.A. Malik^1,2, E. Ajewole¹, J.C. Fredenburgh^1,3, A.R. Stafford^1,3, B.A. Leslie^1,3, H.M. Madarati^1,2, C.A. Kretz^1,3, J.I. Weitz^1,3
Abstract Number: PB1459

Identification of the Sequence Specificity in C-Src SH3 Required for Binding to Integrin Β3 as a Novel Anti-Thrombotic Target without Compromising Primary Hemostasis

J. Mao¹, Y. Wang¹, B. Xiao¹, Z. Long¹, K. Zhu², J. Liu², Z. Ruan¹, W. Xi¹, C. Luo², X. Xi¹
Abstract Number: PB0151

Identification of Thrombosis Predictors in an ex vivo Shunt Model through Retrospective Analysis

M.W. Hagen¹, H.H.S. Lakshmanan², M.E. Fallon², O.J.T. McCarty², M.T. Hinds²
Abstract Number: PB0329

Identification of Zebrafish Orthologue to Human Factor IX Gene and its Age Dependent Regulation

N. Iyer, A. Al Qaryoute, M. Kancham, P. Jagadeeswaran
Abstract Number: PB0658

Identifying and Reducing the Cause of Haemolysis in Coagulation Blood Samples due to Sample Transport in a Pneumatic Tube System

J. Cooper¹, F. Broell², J. van der Hoop², S. Kitchen¹
Abstract Number: PB0691

Identifying DOACs in Mixing Study Samples

E. Salazar, C. Leveque, J. Chen, B. Castillo
Abstract Number: PB1620

Ikaros/AhR Interaction Favors Expansion of Megakaryocytic Precursors with a High Potential to Produce Proplatelets

V. Do Sacramento¹, L. Mallo¹, S. Chan², C. Gachet¹, F. Lanza¹, H. de la Salle¹, C. Strassel¹
Abstract Number: PB1835

Immature Platelet Fraction and Platelet Indices in Acute Coronary Syndrome

Y. Hernaningsih¹, E. Indriastuti¹, Y.N. Indrasari¹, A. Andrianto²
Abstract Number: OC 03.1

Immune Profiling of Previously Untreated Patients with Severe Haemophilia A by High-throughput Mimotope Variation Analysis

G. Baselli¹, R. Palla², C. Valsecchi³, K. Palm⁴, S. Miri⁵, F. Peyvandi^2,3, SIPPET Study Group
Abstract Number: PB1356

Immune Thrombocytopenia Treatment with Fostamatinib, a Spleen Tyrosine Kinase Inhibitor: Reducing the Risk of Thrombosis

N. Cooper¹, I. Altomare², Y. Kreychman³, V. Markovtsov⁴, E. Masuda⁴, S. Tong⁵, J. Bussel⁶
Abstract Number: PB1025

Immune Tolerance Induction (ITI) with a Plasma-derived Factor VIII for Patients with Hemophilia A and Inhibitors: A Retrospective Study

M. Escobar^1,2, L. Shaffer³, M. Holguin⁴, T. McCavit⁵, N. Amega⁶, S. Rajan⁷
Abstract Number: PB1001

Immune Tolerance Induction (ITI) with a Single Factor VIII/von Willebrand Factor Concentrate in Haemophilia A Patients with Inhibitors – Update from the ObsITI Study

C. Escuriola-Ettingshausen, ObsITI Study Group
Abstract Number: PB1086

Immune Tolerance Induction in Children with Hemophilia A, in Times of Emicizumab: A Real Life Experience

J. Ardila¹, J. Argüello², G. Martinez², J. Wilches¹, D. Arias²
Abstract Number: PB1044

Immune Tolerance Induction with Octanate^® in Patients with Haemophilia A and Inhibitors: An Ongoing Case Series from a Malaysian Centre

Z. Muda¹, S. Zainol², H. Ibrahim¹
Abstract Number: PB1047

Immune Tolerance Induction with Simoctocog Alfa in Patients with Haemophilia A: An Ongoing Multicentre Case Series from the UK

G.W. Hall¹, A. Wilkinson¹, M. Mathias², N. Bhatnagar¹, T. Biss³, R.J. Liesner²
Abstract Number: PB2000

Immunization with Recombinant Atherogenic Antigen (AHC) Does Not Enhance Susceptibility to Sepsis

M. Xia¹, V. Endresz², I. Lantos², A. Szabo³, X. Lu¹
Abstract Number: PB0143

Immunization with Recombinant Atherogenic Antigen (AHC) Does Not Increase Susceptibility to Venous Thrombosis

M. Xia¹, V. Endresz², I. Lantos², A. Szabo³, X. Lu¹
Abstract Number: PB2282

Immuno-Magnetic Separation (IMS) Allows Efficient and Selective Extraction of Microvesicles Bearing Tissue Factor Activity from Various Liquid Biopsies

C. Franco^1,2, R. Lacroix^1,3, L. Vallier^1,3, C. Judicone², T. Bouriche², S. Laroumagne⁴, P. Astoul⁴, F. Dignat-George^1,3, P. Poncelet²
Abstract Number: PB0027

Immuno-Radio-Metric TSH in TRH Test of Optimal Substitutive Thyroid Hormones

E.H. Sidibe¹, P.-J. Guillausseau², A. Warnet^3,4
Abstract Number: PB2483

Impact Analysis of Prognostic Stratification for Pulmonary Embolism (iAPP): A Randomized Controlled Trial

M.P. Donadini¹, N. Mumoli^2,3, P. Fenu⁴, F. Pomero⁵, R. Re⁶, G. Palmiero⁷, L. Spadafora⁵, V. Mazzi³, A. Grittini², D. Aujesky⁸, F. Dentali¹, W. Ageno¹, A. Squizzato⁹
Abstract Number: PB2562

Impact of 399C/T Polymorphism of Tissue Factor Pathway Inhibitor on Risk of Recurrent Pregnancy Loss in India

K. Kishor¹, A. Sharma², R. Kumar², S. Maharana³, R. Ranjan², M. Mahapatra², S. Tyagi², R. Saxena²
Abstract Number: PB0975

Impact of a New Drug in the Real Child´s Life

G. Sliba, M. Martinez, P. Nally, F. Morales, G. Dolabella, F. Nally
Abstract Number: PB1281

Impact of a Perioperative Venous Thromboembolism Prophylaxis Screening Tool for Pediatric Orthopedic Surgical Patients

W. MacNevin¹, K. Padhye², V. Price¹, R. ElHawary², B. Branchford³, S. Stevens⁴, K. Kulkarni⁵
Abstract Number: PB1242

Impact of a Standardized, Moderate-Intensity Aerobic Exercise Regimen on Hemostasis in Adolescent Hemophilia A Carriers: A Pilot Investigation

R. Kumar^1,2, M. Carcao^3,4, A. Gonzales⁵, J. Lischak⁵, P. Widener⁵, J. Stanek⁵, A. Waller⁵, B. Kerlin^5,6,7, W. Kahr^3,8, M. Rand^3,8, D. Lillicrap⁹, A. Dunn^5,6
Abstract Number: PB0701

Impact of Anticoagulant and of Time Elapsed Since Blood Collection on Platelet Function Assessed by Multiple Electrode Impedance Aggregometry

M. Hardy^1,2, S. Lessire³, S. Kasikci⁴, J. Baudar⁴, M. Guldenpfennig⁴, J. Douxfils^5,6, J.-M. Dogne⁵, T.P. Lecompte⁷, B. Chatelain⁸, H. Jacqmin⁸, F. Mullier⁸
Abstract Number: PB0812

Impact of APTT Reagents on Factor VIII Assay in Plasma Spiked with a Pegylated Recombinant FVIII: A French Multicentre Study

C. Pouplard^1,2, F. Grand³, I. Harzallah⁴, E. Jeanpierre⁵, D. Lasne⁶, C. Nougier⁷, Y. Repesse⁸, A. Ryman⁹, A.F. Serre Sapin¹⁰, S. Voisin¹¹, C. Ternisien^12,13
Abstract Number: PB2289

Impact of Beta-Blockers on the Clinical Diagnosis of Patients with Pulmonary Embolism

F. Moustafa^1,2, B. Desmarie¹, N. Breuil¹, N. Dublanchet¹, D. Teissandier¹, J. Schmidt^1,2
Abstract Number: PB1313

Impact of Blood Group on the Incidence of Thrombosis in Neonates

K. Bhatia, S. Solanki, B. Paes, A.K. Chan, M.D. Bhatt
Abstract Number: PB0634

Impact of Centrifugation on Thrombin Generation Analysis Evaluated in Healthy Subjects and Patients Treated with Direct Oral Anticoagulants

M. Hardy^1,2, C. Dellanoce³, J. Douxfils^4,5, L. Sarah², A. Carlo⁶, S. Testa³, F. Mullier¹
Abstract Number: PB2324

Impact of Clostridium Difficile Infections on In-Hospital Outcomes of Venous Thromboembolism (DVT or PE) Hospitalizations

K. Jhaveri¹, D. Ludhwani², A. Vakiti³, S. Surani⁴
Abstract Number: PB0537

Impact of Combination of Factor VIII-Deficient Plasma and Activator in One-Stage Clotting Assay on Potency Testing of Factor VIII Products

A. Suzuki¹, N. Suzuki², T. Kanematsu³, S. Okamoto⁴, S. Tamura⁵, T. Kojima⁵, T. Matsushita^2,3
Abstract Number: PB2327

Impact of Competing Risk of Death on the Cumulative Incidence of Venous Thromboembolism in a Nationwide Danish Cohort of Men and Women

C.A.L. Arnesen¹, K. Veres², N. Skajaa², E. Horváth-Puhó², H.T. Sørensen², J.-B. Hansen^1,3, S.K. Brækkan^1,3
Abstract Number: PB0163

Impact of DOACs on Hemostasis Diagnostic Tests. Practical Recommendations and Guidance for the Laboratory

R. Siriez¹, J.-M. Dogné^1,2, J. Laloy^2,3, J. Douxfils^1,4
Abstract Number: PB1059

Impact of Extended Half-life Product versus Conventional Factor Product in Children with Hemophilia A – Findings from a Tertiary Care Centre

M. Saleh¹, H. Alzahrani², T. Owaidah³, A. Aljefri¹, D. Mohammed⁴, B. Safi⁵, V. Mohammed¹
Abstract Number: PB0034

Impact of Gut Microbiota on Late Atherosclerosis and Atherothrombosis: A Study with Germ-Free Mice

G. Pontarollo¹, K. Kiouptsi¹, S. Jäckel^1,2, M. Kuijpers³, C. Weber^4,5, C. Neideck^3,4, M. Nagy³, Y. Jansen⁴, U. Walter^1,2, K. Jurk^1,6, J. Heemskerk³, E. van der Vorst^4,7, Y. Döring^4,7,8, C. Reinhardt^1,6
Abstract Number: PB1287

Impact of Inherited Thrombophilia on Risk of a First Perinatal Arterial Stroke and Futher Course or Recurrence Rates: A Systematic Review and Meta-Analysis of Observational Studies

T. Bajorat¹, B. Kiesau¹, M. Shneyder¹, P.M. Kuta¹, D. Kowalski¹, A. Rocke¹, G. Keneth², R. Junker¹, U. Nowak-Göttl¹
Abstract Number: PB1261

Impact of Intravenous Iron Therapy in Post-menarchal Adolescents Hospitalized with Acute Heavy Menstrual Bleeding

H. Han¹, A.S. Cohen¹, K.A. Staggers², L. Srivaths¹
Abstract Number: PB1615

Impact of Irradiation on the Bone Marrow Matrix and Megakaryopoiesis

K. Faber¹, D. Semeniak¹, K.G. Heinze², H. Schulze¹
Abstract Number: PB2156

Impact of Obesity in Pulmonary Embolism among Patients with Solid Malignancies

K. Quelal¹, A. Torres¹, C. Torres², A. Tafur³
Abstract Number: OC 01.5

Impact of Platelet-Selective TGF-β1-Deficiency in Atherogenesis and CD4+ T Effector Responses Using a No-Germline Genetic Engineering Atherosclerosis Mouse Model

S. Tan¹, Y. Sun², A. Gisterå¹, Y. Min¹, J. Zhang¹, C. Ma², N. Li¹
Abstract Number: PB1039

Impact of Prophylactic Treatment Incorporation in Hemophilia A and B Hospitalization Rates of the State of São Paulo Patients – Brazil – from 2008 to 2018

A.C. Guersoni¹, P. Vilaça², V. Rocha², E. Trindade³, O.D.C. Luiz¹
Abstract Number: PB0091

Impact of Protease Nexin-1 in Cerebral Ischemia

L. Venisse, S. Dupont, Y. Boulaftali, B. Ho-Tin-Noe, V. Arocas, M.-C. Bouton
Abstract Number: OC 12.3

Impact of SERPINC1 Mutation on Thrombotic Phenotype in Children with Congenital Antithrombin Deficiency – First Analysis of the International Society on Thrombosis and Hemostasis (ISTH) Pediatric AT Database and Biorepository

R. Kumar^1,2, N. Bakeer³, A. Al Mughairy^4,5, J. Dawson⁶, J. Stanek⁷, A. Dunn^7,8, A. Chan^9,10, C. Male¹¹, J. Forman-Kay^12,13, S. Williams^4,5
Abstract Number: PB2322

Impact of Socioeconomic Status on the Risk of Receiving a Permanent Work-Related Disability Pension After Incident Venous Thromboembolism

H. Jørgensen¹, E. Horváth-Puhó², K. Laugesen², S. Braekkan^1,3, J.-B. Hansen^1,3, H.T. Sørensen²
Abstract Number: PB0981

Impact of Switching to Prophylaxis with Recombinant Factor IX Fc Fusion Protein Concentrate on Patient Reported Outcomes in People with Haemophilia B Using the PROBE Questionnaire

M. O'Donovan^1,2, K. Johnston^1,2, E. Singleton¹, J. Benson¹, K. Ryan¹, N. O'Connell^1,2
Abstract Number: PB1891

Impact of Ultralarge von Willebrand Factor (VWF) Multimers and Platelets in Cultured Endothelial Cells in Acute Immune-mediated Thrombotic Thrombocytopenic Purpura

C. Vendramin¹, F. Patella², C. Lupo¹, D. Cutler², M. Scully^1,3
Abstract Number: PB2544

Impaired Platelet Contractility in Women with a History of Miscarriage

S.I. Safiullina^1,2, A.D. Peshkova¹, N.G. Evtugina¹, R.I. Litvinov^1,3, J.W. Weisel³
Abstract Number: PB2488

Implementation of a Text-message Intervention to Warfarin Users in a Brazilian Primary Care Setting

M. Viana Rego Souza e Silva¹, M. Luiza de Paiva Rodrigues², A. Oliveira Baldoni², B. Gabriela Rocha², M. Cesar Raposo², T. Lorenna Souza Sales², J. Antonio Queiroz de Oliveira³, A.L. Ribeiro³, M. Soriano Marcolino³
Abstract Number: PB1217

Implementation of Prefilled Doses- A Novel Approach to Decrease Medication Time to Administration and Errors In Critically Ill Pediatric Patients of Emergency Department (ED)

F. Perveen, A. Shah
Abstract Number: PB0282

Implementation of the Management of Anticoagulation in the Periprocedural Period (MAPPP) App into an Electronic Health Record (EHR): A Prospective Cohort Study

A. Spyropoulos^1,2, D. Giannis¹, J. Cohen^2,3, S. John³, A. Myrka⁴, D. Inlall¹, S. Akgul⁵, R. Hyman⁶, J. Wang^1,2
Abstract Number: PB1687

Implication of Platelet Adhesiveness in the Risk of Venous Thromboembolic Disease

D. Jerez¹, M. Diaz-Ricart^1,2, M. Arús³, S. Torramadé-Moix¹, P. Molina¹, A. Ramos¹, M. Carrasco³, N. Villalta³, V. Martinez³, D. Llobet³, P. Sanchez⁴, M. Palomo^1,2,5, F. Vidal^6,7,8, G. Escolar^1,9, J.C. Souto³
Abstract Number: PB0961

Implication of Weight Excess in Hemophilic Arthropathy. The Results of a Colombian Reference Center

J. Lopez-Lopez¹, C. Sossa-Melo², A. Peña-Castellanos³, E.A. Wandurraga², D. Ney-Salazar⁴, J. Otero-Wandurraga⁵
Abstract Number: PB0040

Importance of Arginase-1 in Erythrocytes for Smooth Muscle Cell Calcification and Atherosclerosis

R. Gogiraju¹, L. Renner¹, M. Molitor^1,2, S. Danckwardt², T. Münzel¹, P. Wenzel^1,2, K. Schäfer¹
Abstract Number: PB1639

Importance of Platelet Contractility at Different Stages of Thrombus Formation

M. Kenny^1,2, S. Lickert³, V. Vogel³, D. Kenny^1,2, I. Schoen^1,2
Abstract Number: PB0252

Importance of the Non-Catalytic Heavy Chains of the Homologs Factor XII and HGFA in Protease Function

A. Shamanaev, I. Ivanov, M.-F. Sun, D. Gailani
Abstract Number: PB1764

Important Role for SHARPIN in Supporting Platelet Linear Ubiquitination and Thrombus Formation

S.F. Moore¹, J.L. Huntchinson¹, X. Zhao¹, J. Ivaska², I. Hers¹
Abstract Number: PB1202

Important Sex Differences in Patients with Autosomal Inherited Bleeding Disorders

F. Atiq¹, J.L. Saes², K. Meijer³, M.H. Cnossen⁴, R.E.G. Schutgens⁵, B.A.P. Laros-van Gorkom², M. Peters⁶, L. Nieuwenhuizen⁷, K.P.M. van Galen⁵, J. de Meris⁸, J.G. van der Bom^9,10, F.J.M. van der Meer¹¹, K. Fijnvandraat^6,12, I.C. Kruis⁸, W.L. van Heerde², J. Eikenboom^11,13, S.E.M. Schols², F.W.G. Leebeek¹, WiN and RBIN Study Groups
Abstract Number: PB1274

Improve the Quality of Life in Children with Thrombosis and Need for Oral Anticoagulation: The “Coagulin Project”

R. Martos Martínez¹, M. Yuste Platero¹, E. Gonzalez Arias¹, L. Bermejo Martínez², P. Beltrán Álvarez², A. Pascual Martínez², D. Cornejo Corrales¹, P. Llamas Sillero³
Abstract Number: PB0002

Improved Antithrombotic Activity and Diminished Bleeding Side Effect of a PEGylated αIIbβ3 Antagonist, Disintegrin

Y.-J. Kuo¹, W.-J. Chuang², T.-F. Huang^1,3
Abstract Number: PB0480

Improved Functional and Biochemical Characteristics of Buffy-Coat Platelet Concentrates Stored in Citrate-Free PAS-III Additive Solution for 7 Days

H. Isola, C. Ravanat, F. Rudwill, A. Pongerard, D. Haas, A. Eckly, C. Gachet, B. Hechler
Abstract Number: PB0937

Improved Prophylaxis Adherence After Switching to Emicizumab: Real-World Data from a Single Center

T.W. Buckner, O. Rapacchietta, D. Hill, B. Warren, M. Manco-Johnson, C. Ng, G. Moyer, B. Branchford, R. Shearer, J. Smith, D. Thornhill, M. Wang
Abstract Number: PB1130

Improved Sensitivity of Global Hemostasis Assays Using Different Combinations of Phospholipid Reagent and Tissue Factor

P. Soni, R. Patil, S. Shetty
Abstract Number: PB2457

Improvements in Short- and Long-term Outcomes in Patients with Pulmonary Embolism after Outpatient Pulmonary Rehabilitation

S. Nopp¹, F.A. Klok², F. Moik¹, M. Petrovic³, I. Derka³, C. Ay¹, R.H. Zwick³
Abstract Number: PB0667

Improving Comparability of Optical Aggregometry Results from Automated Coagulation Analyzer Systems Compared with a Manual Aggregometer

F. Prüller¹, J. Rabensteiner¹, A. Riegler², H. Mangge¹, E. Mahla¹, M. Herrmann¹, D. von Lewinski¹
Abstract Number: PB1089

In the Future, Will ADSCs Become the Target Cells for Hemophilia A Gene Therapy?

Z.Y. Yan¹, J. Li¹, Y. Zhu², Y. Xie¹, L. Wang³, X. Wang⁴, H. He⁴, Q. Sun⁴
Abstract Number: PB2019

In Vitro Disruption of Endothelial Barrier Integrity by Heme and by Serum from Patients with Sickle Cell Disease

V.A.G. Santaterra¹, M.M.L. Fiusa¹, B.W. Hounkpe¹, F. Chenou¹, L.N.G. Costa^1,2, D. Garcia-Weber³, I.D.F. Domingos⁴, A.D.S. Araujo⁵, A.R. Lucena-Araujo⁴, M.A. Bezerra⁴, M.N. Santos¹, F.F. Costa¹, J. Millan³, E.V. De Paula¹
Abstract Number: PB0031

In vitro Occlusive Clot Growth and Retraction

B.J.M. van Rooij¹, G. Zavodszky¹, A.G. Hoekstra¹, D.N. Ku²
Abstract Number: PB1716

In-Depth Platelet Releasate Proteome Profiling: A Novel Source of Biomarkers for Early-Onset Preeclampsia

P.B. Szklanna^1,2, M.E.M. Parsons^1,2, K. Wynne³, H. O'Connor⁴, M. Higgins^5,6,7, K. Egan¹, F. Ni Ainle^1,5,8, P.B. Maguire^1,2,9
Abstract Number: PB0016

In-Vivo Biomarkers of Platelet Function in Women with Ischemic Heart Disease: What We Learned from the EVA Study

L. Stefanini¹, G.F. Romiti¹, M. Proietti², S. Bartimoccia³, R. Carnevale³, S. Basili¹, V. Raparelli⁴, EVA Collaborators
Abstract Number: PB0264

In-vivo Evidence for Contact Activation after Implantation of a Left Ventricular Assist Device in Patients with End-stage Heart Failure

O. Liesdek¹, R. Urbanus², L. de Heer^1,3, S. Sebastian⁴, A. Vink⁵, K. Fischer², W. Suyker¹, R. Schutgens²
Abstract Number: PB0238

Inactivation of Tissue Factor Pathway Inhibitor through Specific Citrullination by Peptide Arginine Deiminase 4

R. Koenen¹, S. Thomassen¹, D. Suylen¹, F. Bouwman², T. Hackeng¹
Abstract Number: PB2082

Inappropriate Dosing of Direct Oral Anticoagulants in Older Patients with Non-Valvular Atrial Fibrillation: Impact on Plasma Drug Levels

A.-L. Comans¹, M. Regnier², B. Bihin², F. Mullier³, M. de Saint-Hubert^1,4, A.-L. Sennesael⁵
Abstract Number: PB2109

Incidence and Risk Factors for Venous Thromboembolism (VTE) among Lymphoma Patients in a Southeast Asian Population

V.C.L. Chong^1,2, P.S. Chia³, E.S. Yap^3,4
Abstract Number: PB2362

Incidence and Risk Factors of Venous Thromboembolism in Patients Undergoing Bariatric Surgery

V. Baez¹, H. Latif¹, A.G. Shenoy¹, H. Wang², J.M. Hughes², T.R. Shope³, K. Fitzpatrick¹
Abstract Number: PB2330

Incidence of Chronic Thromboembolic Pulmonary Hypertension: Results from a Longitudinal Prospective Cohort (Osiris Study)

R. Otero-Candelera^1,2, J.L. Lobo-Beristain^2,3, R. López-Reyes⁴, C. Fernández-Capitan⁵, D. Jimenez-Castro^2,6, M. Alfonso-Imizcoz⁷, A. Ballaz-Quincoces⁸, A. Nuñez-Ares⁹, C. Rodriguez-Matute¹⁰, J. De Miguel-Diez¹¹, D. Rodriguez-Chiaradia^2,12, M. Alcalde-Manero¹³, F. García-Bragado Dalmau¹⁴, L. Hernandez Blasco¹⁵, F. Uresandi-Romero¹⁶, O. Madridano-Cobos¹⁷, A. Muriel-García^2,6, M. Monreal-Boch^2,18
Abstract Number: PB0998

Incidence of Factor VIII and IX Inhibitors in Hemophilia A and B in China

X. Dou, X. Song, R. Yang
Abstract Number: PB0880

Incidence of Neutralizing Antibody (Inhibitor) in Previously Untreated Patients (PUPs) with Severe Hemophilia A

S. Apte, R. Phatale, K. Subramanian, A. Joshi
Abstract Number: PB0112

Incidence of Recurrent Ischemic Stroke in Patients without Atrial Fibrillation: A Real-world Study

J. Weaver¹, L. Wang¹, J. Hardin¹, J. Foody², G. Peters², Z. Yuan¹
Abstract Number: LB/CO01.3

Incidence of Venous Thromboembolism in Patients Discharged after COVID-19 Hospitalisation

M.M. Engelen, T. Vanassche, T. Balthazar, E. Claeys, J. Gunst, M. Jacquemin, S. Janssens, N. Lorent, L. Liesenborghs, K. Peerlinck, G. Pieters, S. Rex, P. Sinonquel, L. Van der Linden, C. Van Laer, R. Vos, J. Wauters, A. Wilmer, P. Verhamme, C. Vandenbriele
Abstract Number: PB0867

Incidence, Presentation and Management of Pseudotumors in Hemophilics: A Systemic Review

R. Akbar
Abstract Number: PB2162

Incidence, Risk Factors and Clinical Outcome of Venous and Arterial Thromboembolic Events in Patients Treated with Immune-checkpoint Inhibitors: A Single-center Cohort Study

F. Moik¹, W.-S.E. Chan¹, S. Wiedemann¹, C. Höller², F. Tuchmann², M.-B. Aretin³, T. Fuereder⁴, S. Zöchbauer-Müller⁴, M. Preusser⁴, I. Pabinger¹, C. Ay¹
Abstract Number: PB2298

Incidental Pulmonary Embolism in an Internal Medicine Department

I. Naceur, Z. Zarrouk, F. Said, T. Ben Salem, H. Baccouche, N. Ben Romdhane, M. Khanfir, I. Ben Ghorbel, M. Lamloum, M.H. Houman
Abstract Number: PB1090

Increase in the Treatment Efficacy of Genome Editing for Hemophilia B by Codon-Optimization of SaCas9 in Mice

T. Hiramoto¹, M. Hayakawa¹, N. Kamoshita¹, Y. Kashiwakura¹, H. Nishimasu², N. Osamu², T. Ohmori¹
Abstract Number: PB1899

Increased Baseline Platelet Activation and Decreased Platelet Reactivity in Patients with the Antiphospholipid Syndrome

L. Hell, L.-M. Mauracher, J. Roiß, M. Krall, J. Gebhart, C. Ay, I. Pabinger
Abstract Number: PB2110

Increased Coagulation Potential in Patients with Polycythemia Vera and Essential Thrombocythemia with Thrombotic History

N. Korsakova, O. Golovina, O. Matvienko, N. Silina, E. Efremova, M. Fominykh, V. Shuvaev, S. Voloshin, L. Papayan
Abstract Number: PB/CO15

Increased Doses of Low-molecular-weight Heparin in Hospitalized Patients with Covid-19

I. Martinelli¹, A. Ciavarella¹, M. Abbattista¹, S. Aliberti^2,3, V. De Zan³, C. Folli⁴, M. Panigada⁵, A. Gori^3,6, A. Artoni¹, A.M. Ierardi⁷, G. Carrafiello⁷, V. Monzani⁴, G. Grasselli^3,5, F. Blasi^2,3, F. Peyvandi^1,3
Abstract Number: PB2226

Increased Levels of Procoagulant Factors and the Risk of Venous Thromboembolism

L. Spiezia, E. Vedovetto, M. Marobin, E. Borella, G. Turatti, P. Simioni
Abstract Number: PB0128

Increased Levels of von Willebrand Factor Associated with Acute Inflammation Contribute to Enhanced Venous Thrombosis

S.J. Choi¹, L. Swystun¹, C. Hindmarch², C. Dwyer¹, A. Michels¹, W. Hopman³, D. Lillicrap¹
Abstract Number: PB0830

Increased Plasmin Generation in People with Severe Haemophilia

A.M. Rehill^1,2, S. McCluskey^1,2, M. Lavin^1,2,3, J.S. O'Donnell^1,2,3, R.J.S. Preston^1,2,4
Abstract Number: PB2118

Increased Potential of Neutrophil Activation and Neutrophil Extracellular Trap Formation in Patients with Lung Cancer

L.-M. Mauracher¹, M. Krall¹, F. Moik¹, L. Hell¹, J. Roiß¹, T.M. Hofbauer², C. Brostjan³, C. Ay¹, I. Pabinger¹
Abstract Number: PB1563

Increased von Willebrand Factor Levels in Polycythemia Vera and Phenotypic Differences with Essential Thrombocythemia

M. Sacco¹, S. Lancellotti², G. Petrucci³, P. Ranalli⁴, A. Dragani⁴, E. De Candia⁵, D. Halem⁶, B. Rocca⁷, R. De Cristofaro⁸
Abstract Number: PB1578

Increasing Levels of von Willebrand Factor (VWF) and Factor VIII (FVIII:C) with Age in Patients Affected by von Willebrand Disease (VWD)

E. Biguzzi^1,2, S.M. Siboni³, S. Le Cessie², L. Baronciani³, F.R. Rosendaal², A. van Hylckama Vlieg², F. Peyvandi^4,5
Abstract Number: PB0272

Indiscriminate Coagulation Testing for Bleeding Risk Assessment Prior to Orthopedic Surgery. Is it a Rational Approach?

M. Ali¹, M. Harani²
Abstract Number: OC 14.4

Induction of Innate Immune Memory in Macrophages Profoundly Enhances their Procoagulant and Antifibrinolytic Activity

S. McCluskey^1,2, A. Rehill^1,2, R. Preston^1,2,3
Abstract Number: PB1521

Inertial Forces Generated by a Vortex System Promote Cleavage of von Willebrand Factor

K. Ashworth^1,2, M. Bortot², A. Sharifi³, F. Walker², K. Neeves⁴, D. Bark^2,3, J. DiPaola¹
Abstract Number: PB2405

Inferior Vena Cava Filter (IVCF) Utilization: Quality Assurance at a Quaternary Care Medical Center

J. Choe, R. Liang, A. Weinberg, V. Tapson
Abstract Number: PB1249

Inflammation Associated Cell-Free microRNA Levels in Cerebrospinal Fluid of Premature Infants Upon Intraventricular Hemorrhage

Z. Fejes¹, J. Erdei², J. Takai¹, V. Jeney², A. Nagy³, A. Bácsi⁴, L. Bognár⁵, L. Novák⁵, J. Kappelmayer¹, B. Nagy Jr.¹
Abstract Number: PB0844

Inflammation in Hemophilia Is Marked by Up-regulation of LPS-binding Protein

L.M. Knowles, H. Eichler, J. Pilch
Abstract Number: PB0515

Influence of Anticoagulants on the Biomechanical Phenotype of Platelets

L. Sachs¹, L. Lenkeit¹, J. Wesche¹, A. Greinacher¹, O. Otto², R. Palankar¹
Abstract Number: PB0446

Influence of Antiphospholipid Antibodies on Arterial Thrombosis in Myeloproliferative Neoplasia Patients: One Centre Experience

R. Gerbutavičius¹, R. Dambrauskienė¹, M. Rudžianskienė¹, R. Paukštaitienė², D. Remeikienė¹, A. Vitkauskienė³, E. Skrodenienė³, E. Juozaitytė¹
Abstract Number: PB1761

Influence of Bile Acids on Hemostasis and Arterial Thrombosis

F. Reusswig¹, L. Wienands², M. Reich³, V. Keitel-Anselmino³, M. Elvers²
Abstract Number: PB2311

Influence of Body Mass Index on Outcomes in Patients with Venous Thromboembolism: Insights from GARFIELD-VTE

J.I. Weitz^1,2, W. Ageno³, A.E. Farjat⁴, A.G.G. Turpie¹, S. Haas⁵, S. Goto⁶, S.Z. Goldhaber⁷, P. Angchaisuksiri⁸, H. Gibbs⁹, P. MacCallum^4,10, M. Carrier¹¹, J. Dalsgaard Nielsen¹², G. Kayani⁴, S. Schellong¹³, H. Bounameaux¹⁴, L.G. Mantovani^15,16, P. Prandoni¹⁷, A.K. Kakkar^4,18, on Behalf of the GARFIELD-VTE Investigators
Abstract Number: PB0633

Influence of DOAC Remove on Coagulation Assays During Thrombophilia Testing in Patients Treated with Rivaroxaban or Dabigatran

M. Kovac¹, D. Basaric², B. Tomic³, D. Backovic⁴, S. Lalic Cosic⁴
Abstract Number: PB1840

Influence of HOCl-modified Myeloperoxidase on Platelet and Neutrophil Activity

I. Gorudko¹, D. Grigorieva¹, E. Shamova¹, A. Kohan¹, O. Panasenko², A. Sokolov^2,3
Abstract Number: PB1108

Influence of N-linked Glycosylation in the A and C Domains on the Immunogenicity of Factor VIII

A. Vander Kooi¹, A. Chen¹, J. Joo¹, X. Cai¹, C.-Y. Chen¹, C. Li¹, L. Li², W. Xiao³, B.A. Konkle⁴, C.H. Miao¹
Abstract Number: PB1879

Influence of Personality and Life Conditions on Depression, Anxiety and Cognitive Performance in 104 Patients Having Survived Acute Autoimmune Thrombotic Thrombocytopenic Purpura (iTTP)

T. Falter¹, S. Boeschen¹, M. Beutel², K. Lackner¹, B. Lämmle^3,4,5, I. Scharrer³
Abstract Number: PB0584

Influence of Phospholipids on the Measurement of Extended Half-Life Factor VIII Activity in One-Stage Clotting Assay

Y. Fujimori¹, S. Madoiwa^2,3, S. Shinohara⁴, O. Kumano⁴, N. Arai⁴, A. Igari³, M. Wakui³, M. Murata³
Abstract Number: PB0367

Influence of Specific Therapy on Microparticle-Associated Thrombin Generation in Patients with Primary Myelofibrosis

O. Matvienko, N. Silina, N. Korsakova, O. Golovina, L. Papayan, E. Efremova, M. Fominyh, V. Shuvaev, S. Voloshin
Abstract Number: PB2151

Influence of Tumor Site on Clinical Outcomes in Cancer Patients with Venous Thromboembolism. Insights from the Prospective PREDICARE Cohort Study

P. Girard^1,2, S. Laporte^2,3,4, C. Chapelle^4,5, A. Lamblin⁶, G. Meyer^2,7
Abstract Number: PB0690

Inherited Coagulopathies Study by Massive Sequencing (NGS) Experience of a Diagnostic Portuguese Center

P. Martinho¹, C. Silva Pinto¹, C. Oliveira², M.F. Rodrigues², R. Salvado³, M. Carvalho⁴, M. Calheiros⁵, G. Caetano⁶, L.F. Araújo¹, J. Azevedo¹, P. Kjollerstrom⁷, M. Costa⁸, T. Fidalgo¹, M.L. Ribeiro¹
Abstract Number: PB2236

Inherited Deficiency of Antithrombin, Protein C or Protein S Is Associated with an Increased Risk of Cancer at a Younger Age

D. Tormene¹, S. Gavasso², G. Turatti², C. Simion², M. Marobin², E. Campello², P. Simioni²
Abstract Number: PB1212

Inherited Factor VII Deficiency Associated with Thrombo-hemorrhagic Phenotype: A Case Report

A. Stryckova, M. Dobrotova, L. Lisa, J. Sokol, L. Stanciakova, T. Simurda, L. Vadelova, M. Brunclikova, J. Stasko
Abstract Number: PB1197

Inherited Factor VII Deficiency in Women: Low Rate of Bleeding in Non-severe Disease

F. Chuliber¹, M. Martinuzzo^1,2, V. Privitera³, M. Lopez¹, E. Viñuales³, L. Barrera^2,3, D. Mezzarobba³, M.E. Fotti Berdasco^3,4, M. Villagra Iturre³, M. Trulls^1,4, D. Penchasky³, J. Arbelbide¹
Abstract Number: PB1494

Inherited Platelet Disorders: Identification of Novel Disease Causing Variants Using Next Generation Sequencing

D. Boeckelmann, F. Sobotta, S. Fels, H. Glonnegger, F. Loewecke, A. Lenz, B. Zieger
Abstract Number: PB1174

Inherited Rare Bleeding Disorders in Non-Consanguinity

A. Chuansumrit¹, W. Sasanakul¹, S. Parapakpenjune², R. Natesirinilkul³, P. Komwilaisak⁴, N. Sirachainan for the RBD Study Group.¹
Abstract Number: PB1450

Inherited Thrombocytopenia Associated with Haematological Malignancies

M. Faleschini¹, N. Papa², T. Giangregorio¹, F. Pozzani³, A. Pecci⁴, V. Bozzi⁴, S. Barozzi⁴, P. Noris⁴, C. Marconi⁵, M. Seri⁵, F. Giona⁶, M. Santopietro⁶, D. De Benedictis⁶, A. Savoia^1,2
Abstract Number: PB1425

Inhibition of 12-LOX with VLX-1005 Has Clinical Utility for Prevention and Intervention of HIT

R. Adili, V. Putzbach, M. Holinstat
Abstract Number: PB1559

Inhibition of ADAMTS13 Rescues Acquired von Willebrand Syndrome in a Preclinical Mechanical Circulatory Support Animal Model

S. Deconinck¹, S. Jacobs², C. Nix³, E. Bennek-Schöpping³, C. Vandenbriele⁴, A.-S. Schelpe¹, E. Roose¹, I. Pareyn¹, B. Meyns², C. Tersteeg¹, S.F. De Meyer¹, K. Vanhoorelbeke¹
Abstract Number: PB0407

Inhibition of Factor Xa by Specific Reversible Inhibitors Is Selective for Factor Xa Generated by Factor IXa

C. Kluft¹, N. Klip¹, S. Talens¹, S. Karamzin², F. Ataullakhanov³
Abstract Number: PB1460

Inhibition of Platelet Adhesion, Thrombus Formation and Fibrin Formation by a Potent αIIbβ3 Integrin Inhibitor

D.L. van den Kerkhof, M. Nagy, J.W.M. Heemskerk, T.M. Hackeng, I. Dijkgraaf
Abstract Number: PB0398

Inhibition of Protein Disulfide Isomerase (PDI) with PACMA-31 Amplifies LPS-Induced Expression of Tissue Factor (TF) in Monocytes

L. Beckmann¹, M. Voigtländer¹, B. Sievers¹, A. Schulenkorf¹, C. Bokemeyer¹, W. Ruf^2,3, C.C. Rolling^1,4, F. Langer¹
Abstract Number: PB0153

Inhibitor against Congenital Coagulation Factor XIII Deficiency: A Case Report

M. Karimi¹, A. Shahsavani^1,2, A. Bazrafshan¹, M. Bordbar¹, O. Zekavat¹, H. Tavoosi³, Z. Safarzadeh², A. Bahmanimehr², N. Bolandparvaz³
Abstract Number: PB1192

Inhibitor Development in a Patient with Severe Congenital Factor V Deficiency

N. Pardy^1,2, P. Moorehead^1,3
Abstract Number: PB1013

Inhibitor Development in Hemophilia A – Refining the Risk Assessment

A. Duraes
Abstract Number: PB1575

Inhibitor Development in Patients with Type 3 von Willebrand Disease, a Comprehensive Study on a Large Number of Iranian Patients

G.R. Bahoush^1,2, S. Tabibian^2,3, M.R. Baghaipour², F. Ala², M. Jazebi², A. Dorgalaleh^2,3, R. Hantooshzadeh⁴, N. Baghaipour⁵
Abstract Number: PB1083

Inhibitor Epidemiology among People Living with Haemophilia A in South West Nigeria

A. Bolarinwa, A. Olatinwo, L. Adiat, T. Adeyemo
Abstract Number: PB1079

Inhibitor Formation and Immune Tolerance Induction with Fc-fusion-Protein Recombinant Factor IX in Severe Hemophilia B

A. Amid¹, H. Perkins¹, A. Bonnefoy², J. Gauthier², M. Carcao³, G.E. Rivard², R. Klaassen¹
Abstract Number: PB0325

Inhibitor Risks Estimation Associated with F9 Genotype Types in Patients with Severe Haemophilia B: Argentine vs EAHAD Database

P. Radic¹, B. Ziegler¹, V. Marchione¹, K. Waisman¹, M.M. Abelleyro¹, M. Williams², D. Neme³, C.D. De Brasi^1,4, L. Rossetti¹
Abstract Number: PB0913

Inhibitors in Hemophilia: Treatment Challenges in Afghanestan

S.H. Mousavi^1,2, S.A. Mesbah-Namin³, M. Jazebi⁴, A. Dorgalaeh⁵, S. Zeinali^6,7
Abstract Number: PB1887

Inhibitory Anti Adamts13 Antibodies with a New Rapid Fully Automated Clia Assay

B. Montaruli¹, C. Novelli², L. Solfietti³, A. Valpreda⁴, M. Bazzan³, I.L. Beverina², D. Roccatello³, D. Cosseddu⁵
Abstract Number: PB1993

Inhibitory Effect of Heparin and Modified Heparin on Neutrophil Migration

J. Hogwood¹, Y. Qiao², R. Amison², S. Pitchford², B. Mulloy², E. Gray^1,2
Abstract Number: PB1416

Insights into Autoimmune Heparin-Induced Thrombocytopenia

N. Krause, J. Eekels, A. Greinacher
Abstract Number: PB0684

Institutional Review of Reflex Factor Coagulation Testing in Patients with an Unexplained Prolonged aPTT

E.M. Mansory¹, F. Bahodi², C.W. Phua¹
Abstract Number: PB0525

Inter-Centre and Inter-Observer Agreement of Determination of DOACs in Urine Samples of Patients by Means of DOAC Dipstick Test

J. Harenberg^1,2, R. Bauersachs³, J. Beyer Westendorf^4,5, M. Crowther⁶, J. Douxfils^7,8, I. Elalamy^9,10, S. Hetjens¹¹, P. Verhamme¹², C. Weiss¹¹
Abstract Number: PB0386

Inter-Laboratory Variability of the Standardized ETP-Based APC Resistance Assay

L. Morimont^1,2, V. Maloteau², P. Devel², J.-M. Dogné², C. Bouvy¹, J. Douxfils^1,2
Abstract Number: PB1646

Interaction between Platelets and Streptococcus pneumoniae

A.F. Aschenbrenner¹, S. Handtke¹, T.P. Kohler², S. Hammerschmidt², A. Greinacher¹
Abstract Number: PB1415

Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies as Investigated in Platelet Aggregation Assays

A. Farooqui¹, D. Hoppensteadt¹, O. Iqbal¹, C. Bacher¹, M. Lewis¹, J. Walenga¹, A. Kouta¹, W. Jeske¹, B. Lewis², J. Fareed¹
Abstract Number: PB0494

Interest of Improved Z-Score Bivariate Analysis: Application to a ECAT DDimer Survey

F. Sobas¹, P. Tsiamyrtzis², C. Nougier¹, E. Jousselme¹, M.O. Geay Baillat³, M. Beghin⁴, P. Meijer⁵
Abstract Number: PB0695

Interference of C – Reactive Protein Level in Activated Partial Thromboplastin Time

M. Farana Matos, C. Finazzo, E. Taniguchi
Abstract Number: PB1760

Interplay between the Tyrosine Kinases Chk, Csk and Phosphatase CD148 Is Critical for Regulating Platelets in Mice

Z. Nagy^1,2, J. Mori¹, V.-S. Ivanova¹, A. Mazharian^1,3, Y.A. Senis^1,3
Abstract Number: PB0014

Interventions Needed in Antithrombotic Therapy in a Real Life Hospitalized Population; Evaluation of Interventions Initiated by a Multidisciplinary Antithrombotic Team Regarding Antithrombotic Agent Combinations in In-Patient Care

M. van der Veer¹, J. Schroeder-Tanka², S. van Wissen³, N. Khorsand¹
Abstract Number: PB1407

Intra-individual Residual Platelet Reactivity upon Antiplatelet Therapy in the Perioperative Period Significantly Differs over Time – What Is the Ideal Moment to Monitor Efficacy of Antiplatelet Therapy in Vascular Patients?

N.C. Roozendaal¹, A.R.T. Brand¹, R.T. Urbanus², G.J. De Borst¹, S. Korporaal³
Abstract Number: PB2087

Intracardiac Levels of Soluble P Selectin Is Associated with Ischemic Stroke Risk in Patients with Atrial Fibrillation

F. Sarkady¹, O. Hajas², A. Kiss², E. Nagy-Baló², K.B. Kovács³, Z. Csanádi², L. Csiba³, Z. Bagoly^1,4
Abstract Number: PB0850

Intracellular Visualization of FVIII Protein in Selected Knockouts in the Conventional and Alternative Secretion Pathways

H. Singer, S. Hazzouri, M. Rath, J. Oldenburg, O. El-Maarri
Abstract Number: PB2116

Intracranial Hemorrhage with Direct Oral Anticoagulants in Patients with Brain Metastases

A. Leader^1,2, E.N. Hamulyák³, B.J. Carney⁴, M. Avrahami², J.J. Knip³, S. Rozenblatt⁵, L.F.M. Beenen⁶, S. Yust-Katz^2,7, M. Coppens³, P. Raanani^1,2, S. Middeldorp³, H.R. Büller³, J.I. Zwicker⁴, G. Spectre^1,2
Abstract Number: PB0026

Intravenous Lipid-Based Encapsulated Paclitaxel Nanoparticles Administration Enhances 5-Aminolevulinic Acid- Mediated B- Mode Ultrasound- Guided Focused- Electrohydraulic Shock Wave Sonodynamic Therapy of Intermediated Stage Atherosclerosis

H. Mehrad¹, H. Ahmadi Nobari²
Abstract Number: PB1139

Intravenous Synthetic Platelet Nanotechnology for the Treatment of Bleeding Complications

A. Sen Gupta
Abstract Number: PB1531

Investigating Pathomolecular Mechanisms of Type 2A VWD Variants Located in D1 and A Domains of the VWF

H. Yadegari, A. Biswas, J. Oldenburg
Abstract Number: PB1544

Investigating the Relationship between VWF Multimeric Pattern and VWF: RCo Activity through Population PK Modeling in Patients with Severe VWD Treated with Recombinant VWF

A. Bauer¹, G. Smania², S. Friberg-Hietala², B. Ploder¹, B. Mellgård³, M. Wolfsegger¹
Abstract Number: PB1102

Investigating the Stability of Lentiviral Vector Targeted Liver Cells during Post-Natal Growth for in Vivo Gene Therapy of Hemophilia

M. Milani¹, F. Starinieri^1,2, C. Canepari^1,2, T. Liu³, F. Moalli⁴, G. Ambrosi^2,4, T. Plati¹, M. Biffi¹, C. Covino⁴, T. Nichols⁵, M. Iannacone⁴, R. Peters³, L. Naldini^1,2, A. Cantore^1,2
Abstract Number: PB2036

Investigation of a Significant Factor to Improve an Establishment of Endothelial Colony Forming Cell

S. Okamoto¹, N. Suzuki², T. Kanematsu³, A. Suzuki⁴, K. Odaira⁵, M. Tokoro⁵, Y. Hayakawa⁵, S. Tamura⁵, F. Hayakawa⁵, H. Kiyoi¹, T. Kojima⁵, T. Matsushita⁶
Abstract Number: PB2522

Investigation of Risk Factors of Deep Vein Thrombosis during Pregnancy Using a CFD Model

Q. Jimoh-Taiwo, R. Haffejee, M. Ngoepe
Abstract Number: PB0308

Investigation of Several Four Factor PCCs to Restore Thrombin Generation Following Anticoagulation with Rivaroxaban: Ex vivo Study

K. Deventer, F. Rayadoost, H. Sieben, O. Grottke
Abstract Number: PB0300

Investigation of the Coagulation Potential of PAS-E Resuspended Platelets

A. Lotens¹, S. Horman², A. Rapaille¹, S. Eeckhoudt³
Abstract Number: PB2446

Investigation of the Optimal Dose of aPCC in Reversing the Effect of Factor Xa Inhibitors Rivaroxaban and Apixaban- an in vitro Study

N.H. Schultz^1,2,3, J. Fareed⁴, P.A. Holme^1,2,5
Abstract Number: PB1376

Investigations of the Impact of Sialidase-mediated Changes on the Life Span of Human Platelets Using a Humanized in vivo Mouse Model

L. Pelzl¹, I. Marini¹, J. Zlamal¹, K. Althaus^1,2, T. Bakchoul^1,2
Abstract Number: PB1040

Is intracranial haemorrhage in haemophilia patients still a present risk in the third millennium? The final results of the EMO.REC Registry: a 10-year Italian study on intracranial haemorrhage in haemophilia patients

E. Zanon¹, S. Pasca², F. Demartis³, A. Tagliaferri⁴, C. Santoro⁵, I. Cantori⁶, A.C. Molinari⁷, C. Biasioli⁸, A. Coppola⁴, G. Castaman³, S. Linari³, M. Luciani⁹, G. Sottilotta¹⁰, I. Ricca¹¹, B. Pollio¹¹, A. Borchiellini¹², E. Santagostino¹³, P. Simioni¹⁴
Abstract Number: PB2355

Is Low Molecular Weight Heparin-Calibrated Chromogenic Anti-Xa Assay Suitable for Assessing Anticoagulant Effect of Apixaban in Adolescents?

I. Ćelap¹, S. Margetić¹, R. Mihić¹, J. Obuljen², I. Linarić², J. Leniček Krleža²
Abstract Number: PB2233

Is May-Thurner Syndrome a Forgotten Cause of Deep Vein Thrombosis?

S. Lopes, R. Pombal, L. Vieira, D. Ferreira, H. Cruz Gomes, M. Figueiredo
Abstract Number: PB1824

Is Platelet Hyper-Reactivity a Modifiable Risk Factor in Inflammatory Arthritis?

D. Kenny¹, E. Dunne¹, K. Leamy², G. McCarthy²
Abstract Number: PB1084

Is Radiosynovectomy a Tool in Advanced Hemophilic Arthropathy?

G. Ocampos¹, F. Farias¹, E. Okazaki², P. Villaca², M. Rezende¹
Abstract Number: PB2373

Is the Caprini Score a Reliable Tool to Predict the Risk of Venous Thrombosis in Orthopedic Patients?

R. Zambelli^1,2, B. Nemeth³, C. Touw³, F. Rosendaal³, S. Rezende¹, S. Cannegieter³
Abstract Number: PB1881

Is Therapeutic Plasma Exchange (TPE) Still Necessary for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP)?

P. Knoebl¹, J. Thaler¹, M. Krstic², W. Grandits², W. Sperr¹
Abstract Number: PB2265

Is There a Predictive Value of High Mean Platelet Volume in Early Diagnosis of Venous Thromboembolism in the Emergency Department?

A. Braester^1,2, G. Stemer³, S. Khouri⁴, M. Barhoum^2,4, B. Raviv^5,6
Abstract Number: PB1280

Ischemic Strokes in Children

K. Papayan, M. Rakova, E. Dzhanklich, A. Gurina, E. Kvapinskaya, A. Morozova, A. Shulat'eva, N. Nemstsveridze
Abstract Number: PB1168

Isolated Factor VII Deficiency

A. Amira, D. Nourhan, B. Hacene, O. Hanifa
Abstract Number: PB1246

Isolated Thrombocytopenia in Children Is Not Always an Immune-Associated Disorder

A. Adramerina¹, A. Teli¹, A. Moraitis¹, S. Theodoridou², M. Economou¹
Abstract Number: PB0615

ISTH SSC Plasma Standard Lot #5 – Results in a UK National External Quality Assessment Scheme for Blood Coagulation (NEQAS BC) Exercise

I. Jennings, S. Kitchen, D. Kitchen, S. Munroe-Peart, A. Lowe, L. Brown, I. Walker
Abstract Number: PB1906

IVF Outcomes in Women with Antiphospholipid Antibodies Circulation

J. Khizroeva, A. Makatsariya, V. Bitsadze, M. Arslanbekova, K. Sultangadzhieva