ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB2096

L-Asparaginase Induced Hyperlipidemia, Pseudohyponatremia and Cerebral Venous Thrombosis during Acute Lymphoblastic Leukemia Remission Induction Therapy

H. Uzel¹, M. Soker¹, K. Öncel¹, K. Yilmaz¹, S. Söker²
Abstract Number: PB0434

Laboratory Accuracy Assessment of a Novel INR Point-of-Care Test Compared with Laboratory Reference Methods Used Across Four Independent Clinical Sites

K. Taggart¹, A. Roodt², A. Paget³, J. Ellis³
Abstract Number: PB0589

Laboratory Analysis of Half-Life-Prolonged Coagulation Factors VIII Rurioctocog Alfa Pegol and IX, Nonacog Beta Pegol and of rVWF – Vonicog Alpha in Spiked Human Plasma Samples – First Results of a Multicentre Study by the Austrian Laboratory Societies ÖGLMKC and ÖQUASTA

M. Stuebler¹, J. Seier², E. Wimmer², J. Cadmuro³, P. Fraunberger⁴, A. Griesmacher⁵, C. Irsara⁵, R. Hauer⁶, F. Prueller⁷, P. Quehenberger⁸, J. Radek⁹, A. Schlagenhauf¹⁰, S. Sussitz-Rack¹¹, J. Tomasits¹², A.C. Haushofer²
Abstract Number: PB0580

Laboratory Assessment of Efficacy and Safety of Direct Oral Anticoagulants in Real Clinical Practice

N. Vorobyeva¹, E. Melnichuk², A. Schapkov², N. Shemiakina¹
Abstract Number: PB1593

Laboratory Monitoring of Perioperative von Willebrand Factor Replacement

C. Rothschild¹, D. B. Siqueira¹, E. Okazaki¹, P. R. Villaca¹, T. R.F. Rocha², V. Rocha³
Abstract Number: PB0519

Laboratory Test Ordering Practices for Suspected Heparin-Induced Thrombocytopenia

P. Lindholm¹, K. Carmichael², R. Sumugod², K. Martin³
Abstract Number: PB0675

Laboratory Validation of a Novel Hexagonal Phase Phospholipid Neutralization Assay for Lupus Anticoagulant Detection

C. Douglas, R. Clarke, N. Kesavan, D. Lamont, A. Sadeghi-Khomami, A. Wood, K. Black
Abstract Number: PB1902

Laboratory versus Point-of-Care INR Measurement in Patients with Lupus Anticoagulant – A Retrospective Cohort Analysis

O. Cohen^1,2, M. Misgav^1,2, G. Kenet^1,2, A. Lubetsky^1,2
Abstract Number: PB2502

Lack of Association between the Use of Female Hormones and Platelet Volume Indexes: Evidence from the Longitudinal Study of Adult Health (ELSA-Brasil)

D. Rios¹, T. Resende¹, C. Maluf², A.L. Ribeiro², M.D.G. Carvalho¹, S. Barreto², D. Chor³, E. Aquino⁴, R. de Figueiredo¹
Abstract Number: PB2530

Lack of Disease Modification of HbF on Pregnant Women with Sickle Cell Disease

C. Kenworthy¹, A. Crouch¹, V. Bonham², C. Minniti^1,3, H.H. Billett^1,3
Abstract Number: PB1049

Lack of Inhibitor Development after Switching to Rurioctocog Alfa Pegol in the American Thrombosis and Hemostasis Network (ATHN) 2: Factor Switching Study

J. Journeycake¹, J. Caicedo², D. Cheng³, M. Denne², C. Guelcher⁴, S. Lattimore⁵, M. Ragni⁶, M. Recht³, R. Sidonio^7,8, C. Takemoto⁹, M. Tarantino¹⁰, C. Watson³, E. Neufeld⁹
Abstract Number: PB1510

LAD III, Platelet Pathology Related to GT: A Case Report

K. Mendi^1,2, M. Dahmane^1,2, V. Jallu³, R. Petermann³
Abstract Number: PB1675

Large and Small Platelets Differently Contribute to Whole-Blood Thrombus Formation

S. Handtke¹, B. Tullemans², S. Brouns², A. Veninga², K. Aurich¹, A. Greinacher¹, J. Heemskerk², T. Thiele¹
Abstract Number: PB0467

LBP as a Novel Plasma Protein Associated to Venous Thromboembolism

Á. Fernández-Pardo¹, J. Oto¹, N. Fuster-Valls², D. Hervás³, L. Martos¹, E. Plana⁴, F. Cana¹, A.R. Cid⁵, S. Bonanad⁵, F. España¹, P. Medina¹, S. Morais², S. Navarro¹
Abstract Number: PB2202

Leukocyte Gene Expression in Post-Thrombotic Syndrome

A.F.J. Iding^1,2, A. Witten³, A. Isaacs⁴, E. Castoldi², H. ten Cate^1,2,5, M. Stoll^2,3, A.J. ten Cate-Hoek^1,2
Abstract Number: PB2501

Levonorgestrel Releasing Intrauterine System (LNG-IUS) in a Patient with Deep Endometriosis, Adenomyosis and Behcet´s Disease: Case Report

L.C. Sakamoto¹, R.V. Cruz^1,2, M. Fleury¹, C. Lemos¹, A. Malavasi¹, L.H. Gebrin¹
Abstract Number: PB0197

Library Screening and Combinatorial Approaches Identify an Alpha-1 Proteinase Inhibitor Variant with Enhanced Specificity for Factor XIa

V. Bhakta¹, M. Hamada², A. Nouanesengsy², J. Lapierre², D. Perruzza², W. Sheffield^1,2
Abstract Number: PB0512

Lidocaine Effects on Coagulation Assessed by Whole Blood Rotational Thromboelastometry

E. Scarlatescu¹, S.P. Marchenko², D.R. Tomescu^1,3
Abstract Number: PB0869

Limited Port-A-Cath Need for Hemophilia Patients in the Past: Experience in a Single Center

K. Kavakli^1,2, C. Balkan¹, A. Erdener², N. Karadaş¹, S. Onen¹, D. Yilmaz Karapinar¹
Abstract Number: PB1721

Lipidome Profile in Platelets from Obese Patients: New Assistances of Platelet Dysfunction in Obesity

M. Nuñez Barrachina¹, G. Chicanne², J. Bertrand-Michel³, M. Pardo⁴, B. Payrastre², Á. García¹
Abstract Number: PB0123

Liquorice and Sumac Attenuate Brain Damage Caused by Ischemic Stroke in Rat

A. Parsa¹, R. Majidian², S. Abasi¹, F. Modjtahedi³, M. Babaeian¹
Abstract Number: PB1674

Liver Diseases Contribute to Functional Platelet Aggregation Defects

C. Bacher, A. Farooqui, F. Siddiqui, B. Daravath, D. Hoppensteadt, O. Iqbal, J. Fareed
Abstract Number: PB0354

Liver Dysfunction Biomarkers Correlate with a Prothrombotic and Not with a Prohemorrhagic Hemostatic Profile in Cirrhotic Patients

M.G. Zermatten¹, M. Fraga², D. Bertaggia Calderara¹, A. Aliotta¹, D. Moradpour², L. Alberio¹
Abstract Number: PB1883

Lombardy Network for the Study and Treatment of Patients Undergoing Apheresis

I. Mancini¹, P. Agosti¹, M. Boscarino², B. Ferrari², A. Artoni², R. Palla¹, L. Barcella³, A. Falanga^3,4, F. Peyvandi^1,2, Lombardy AREU TMA Network
Abstract Number: PB1357

Long Term Complications after Splenectomy in Chronic pITP Patients: A Retrospective Case Control Study

M. Marcosano¹, A. Ferretti¹, E. Baldacci¹, F. Paoloni², S. Aprile¹, A. Chistolini¹, A. Serrao¹, M.G. Mazzucconi¹, C. Santoro¹
Abstract Number: PB0860

Long Term Joint Outcomes through Ultrasound for Hemophilia: First Interim Results from Prospective J-DaUPHIN Study

A. Nagao¹, H. Takedani², T. Suzuki¹
Abstract Number: PB1178

Long-Term Anticoagulant Treatment in Patients with Factor VII Deficiency: A Single Centre’s Experience

B. Moriano, N. Bermejo, A. Rodriguez, M. Espina, L. Ramos, M.J. Arcos, I. Casas, O. Ferre, F. Carnicero, S. Caceres, R. Cardesa, F. Ibañez, J. Bergua
Abstract Number: PB2464

Long-term Anticoagulant Treatment of Splanchnic Venous Thrombosis in High Risk Patients: Direct Oral Anticoagulants vs Vitamin K Antagonists

A. Serrao¹, M. Merli², B. Lucani², F. Aprile², L. Fiori², S.M. Aprile², A. Ferretti², C. Santoro², A. Chistolini¹
Abstract Number: PB0999

Long-Term Immunogenicity, Efficacy and Safety of Simoctocog Alfa in Patients with Severe Haemophilia A who Had Completed the NuProtect PUP Study

R.J. Liesner, GENA-15 Study Group
Abstract Number: PB2550

Long-term Incidence of Venous Thromboembolic Recurrence After a First Venous Thrombotic Episode During Pregnancy

M. Ibrahim-Kosta^1,2, S. El Harake³, L. Goumidi², C. De Mari³, J.-F. Secondi³, D. Brunet¹, M.-C. Barthet¹, P. Suchon^1,2, P.-E. Morange^1,2, G. Sarlon-Bartoli^2,3
Abstract Number: PB0522

Long-Term Internal Quality Control Management: The Interest of Bayesian Inference

F. Sobas¹, K. Bourazas², M.O. Geay³, M. Beghin⁴, E. Jousselme⁵, C. Nougier⁵, P. Tsiamyrtzis⁶
Abstract Number: PB2416

Long-Term Management of Anticoagulants in Patients with Cancer-Associated Thrombosis (CAT) Beyond 6 Months: A 432-Patient Retrospective Non-Interventional Study

L. Plaisance¹, C. Chapelle², S. Laporte², B. Planquette³, L. Bertoletti⁴, N. Falvo⁵, F. Coururaud⁶, L. Falchero⁷, I. Mahé⁸, H. Helfer⁹, J. Chidiac⁹, G. Meyer¹⁰, I. Mahé¹¹, USCAT Group
Abstract Number: PB2048

Long-term Mortality and Functional Status in Older Adults with Atrial Fibrillation After Stroke

A. Parks¹, M. Fang², S.Y. Jeon³, A. Smith⁴, M. Steinman⁴, S. Shah⁵
Abstract Number: PB0950

Long-Term Safety and Efficacy of Emicizumab for up to >5 Years in a Phase 1/2 Study in Patients with Severe Hemophilia A

M. Shima¹, A. Nagao², M. Taki³, T. Matsushita⁴, K. Oshida⁵, K. Amano⁶, S. Nagami⁷, N. Okada⁷, K. Nogami¹
Abstract Number: PB2114

Long-Term Use of Tinzaparin for the Treatment of Cancer-Associated Thrombosis: A Subgroup Analysis of the Prospective Observational TROPIQUE Study

C. Frere^1,2, P. Debourdeau³, A. Lamblin⁴, N. Falvo⁵, Y. Benhamou⁶, M.-A. Sevestre⁷, D. Farge^1,8,9
Abstract Number: PB1387

Long-term Variation of Platelet Reactivity in High-Risk Patients on Antiplatelet Therapy after Percutaneous Coronary Intervention

R. Olie^1,2, J. Roelofs¹, L. Veenstra³, Y. Henskens⁴, M. Vries², P.E.J. van der Meijden², H. ten Cate^1,2
Abstract Number: PB1087

Long-Term Vector Genome Outcomes and Immunogenicity of AAV FVIII Gene Transfer in the Hemophilia A Dog Model

P. Batty¹, C.R. Sihn², J. Ishida², A.M. Mo¹, B. Yates², C. Brown¹, L. Harpell¹, A. Pender¹, C. Russell², S. Sardo Infirri¹, R. Torres², A. Winterborn³, S. Fong², D. Lillicrap¹
Abstract Number: PB0878

Longitudinal Analysis of rFVIIIFc Use and Efficacy in the UK: A Report from the National Haemophilia Database

C. Wall¹, M. Scott¹, H. Xiang², B. Palmer², P. Collins³, P. Chowdary⁴, G. Dolan⁵, N. Curry⁶, D. Allsup⁷, C. Hay², D. Hart⁸, UK National Haemophilia Database
Abstract Number: OC 07.4

Longitudinal Assessment of ADAMTS13-activity Helps Predict Recurrence of Immune Thrombotic Thrombocytopenic Purpura (iTTP): Results from the German TTP-registry

C. von Auer-Wegener^1,2, I. Schmidtmann³, L. Bach¹, M. Hehmann¹, T. Falter^2,4, H. Rossmann^2,4, K. Jurk², R. Conradi⁵, D. Marandiuc⁵, I. Scharrer⁶, B. Lämmle^7,8, M. Theobald¹
Abstract Number: PB0562

Loop-Mediated Isothermal Amplification without DNA Extraction for Simultaneous Detection of Factor V Leiden and Prothrombin-G20210A Genetic Variants

G.L. Tiscia¹, P. Vergura¹, D. Colaizzo¹, G. Favuzzi¹, A. De Laurenzo¹, E. Chinni¹, G. Vecchione¹, L. Detemmerman², L. Fischetti¹, E. Grandone¹
Abstract Number: PB1762

Loss of the Exocyst Complex Component, EXOC3, Accelerates Arterial Thrombosis

T. Walsh, Y. Li, A. Poole
Abstract Number: PB/LB02

Low 1-Year Venous Thromboembolic Recurrence Rates in Patients with and without Thrombotic Risk Factors in Routine Clinical Practice Treated with Edoxaban: The Global ETNA-VTE Study

A. Cohen¹, C. Chen², K.-M. Chiu^3,4, W.-I. Choi⁵, M. Nakamura⁶, W. Zierhut⁷, P.-E. Reimitz⁸, M. Unverdorben², G. Agnelli⁹
Abstract Number: PB2499

Low Dose Warfarin (LDW) for the Prevention of Hypercoagulation of Blood and Venous Thromboembolism (VTE) in Women Receiving Hormone Replacement Therapy (HRT)

V. Sukhanov¹, N. Vlasova², O. Petrova³
Abstract Number: PB0757

Low Fibrinolytic Activity Following Ischemia Reperfusion Is Not a Single Etiology: Fibrinolysis Shutdown versus Hypofibrinolysis

H. Moore¹, M. Cohen², C. Walker¹, T. Ferrell¹, E. Moore², A. Stem¹, J. Pomposelli¹, E. Pomfret¹, T. Nydam¹
Abstract Number: PB2023

Low Levels of Circulating Extracellular Vesicle-Encapsulated HULC Are Associated with Left Ventricular Hypertrophy in Japanese

S. Fujii¹, K. Akasaka¹, K. Takahashi²
Abstract Number: PB0565

Low Molecular Weight Heparin Calibrated Anti-Xa Assays can Identify Patients with Low Apixaban or Rivaroxaban Drug Levels

S. Mithoowani¹, A. Gupta², K. Moffat^1,3, S. Carlino³, M.A. Crowther¹
Abstract Number: PB2523

Low Molecular Weight Heparins in the Prevention of Placenta-Mediated Complications in Carriers of the Prothrombin G20210A Mutation

M. Nikolaeva^1,2, A. Momot^1,2, M. Zainulina^3,4, N. Yasafova⁵
Abstract Number: PB0280

Low Preoperative Antithrombin Activity Is Associated with Increased Red Cell and Plasma Transfusion during Neonatal and Infant Cardiac Surgery

Z.A. Fang¹, E. Gottlieb², E. Menard³, D. Vener⁴, V. Kostousov⁵, K. Bruzdoski⁵, L. Hensch⁵, S.R. Hui⁵, J. Teruya⁵
Abstract Number: OC 02.5

Low α2-plasmin Inhibitor Antigen Levels on Admission Predict Unfavorable Outcomes in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis

R. Orbán-Kálmándi¹, B. Baráth¹, F. Sarkady¹, E. Székely¹, I. Szegedi², K.R. Czuriga-Kovács², I. Fekete², K. Fekete², É. Katona¹, L. Csiba², Z. Bagoly^1,3
Abstract Number: PB0511

Low-Angle Light Scattering for the Analysis of the Platelet Functions: Preanalytical Variables and Evaluation in Pediatric Patients

G. Svidelskaya¹, A. Ignatova², A. Poletaev², E. Seregina², P. Zharkov², I. Mindukshev³, S. Gambaryan³, M. Panteleev²
Abstract Number: PB0990

Low-Dose Prophylaxis versus On-Demand Treatment in Pakistan with Severe Hemophilia A: Updated

M. Borhany¹, M. Abid¹, R. Ahmed², A. Jamal², S. Zafar¹, T. Shamsi¹
Abstract Number: PB1115

Low-Factor Consumption and Cost Effectiveness for Surgeries in Hemophilia B Patients with N9-GP

S. Okamoto¹, T. Matsushita², T. Kanematsu², A. Suzuki², S. Tamura³, T. Kojima³, N. Suzuki²
Abstract Number: OC 01.2

Low-grade Endotoxaemia Enhances Artery Thrombus Growth via Toll-like Receptor 4: Implication for Myocardial Infarction

C. Nocella¹, R. Carnevale², S. Sciarretta², V. Cammisotto², V. Valenti², C. Calvieri², G. Frati², G. D'Amati², R. Cangemi², A. Arrivi³, M. Dominici³, E. Mangeri², C. Gaudio², G. Tanzilli², F. Violi²
Abstract Number: PB1067

Lower Incidence of Cardiovascular Disease in Patients with Haemophilia

P. van der Valk¹, M. Makris², R.C. Tait³, P. Chowdary⁴, P.W. Collins⁵, K. Meijer⁶, R.E.G. Schutgens¹, K. Fischer¹, E.P. Mauser-Bunschoten¹
Abstract Number: PB1786

Lung Vessels Thrombosis Induced by Severe CAP: 3D Model of Thrombus

M. Krykhtina, K. Bielosludtseva, T. Pertseva
Abstract Number: PB1898

Lupus Anticoagulant and Antiphospholipid Antibodies: A Real-World Study

E. Kempers¹, V.A.S.H. Dalm², M.J.E. van Rijn³, A.G.M.G.J. Mulders⁴, F.W.G. Leebeek¹, M.P.M. de Maat¹, A.J.G. Jansen¹
Abstract Number: PB1936

Lupus Anticoagulant Testing in Patients with Prolonged INR, Mixing Test Results

T. Villalba, J. Medina, M. Diaz
Abstract Number: PB1908

Lupus Anticoagulant-Hypothrombinemia Syndrome (LAHS): A Case Report

K. Mayani, P. Machado Machado, J.M. Raya Sánchez, M. Pardina Echevarría, C. Lacalzada Higueras, B. Pérez Pinilla, M.T. Hernández García
Abstract Number: PB1649

LV-AO Angle Is Associated with Platelet Reactivity in Patients with Aortic Stenosis

P. Mourikis¹, S. Zako¹, L. Dannenberg¹, R. M'Pembele¹, T. Hohlfeld², T. Zeus¹, M. Kelm¹, V. Veulemans¹, A. Polzin¹
Abstract Number: PB1816

Lyophilized Human Platelets Exhibit Adhesive Interactions with Staphylococcus aureus

A. Lee, K.A. Moskowitz
Abstract Number: PB1533

Lyophilized Human Platelets Show Hemostatic Function Independent of von Willebrand Factor

B. Ishler¹, M. Dickerson¹, A. Lee¹, A. Hale², K. Moskowitz¹
Abstract Number: PB0232

Lysine Residues Impair the Efficacy of N-glycosylation: Pathological and Physiological Relevance in Antithrombin

M.E. de la Morena-Barrio¹, P. Fautrad², A. Miñano¹, C. Bravo-Perez¹, B. de la Morena-Barrio¹, J. Padilla¹, D.A. Tregouet³, P.M. Sandset⁴, V. Vicente¹, P.E. Morange², J. Corral¹
Abstract Number: PB1391

Lysine-Containing Peptides as Promising Antiplatelet Drugs

M. Grigorjeva, L. Lyapina
Abstract Number: PB2368

Lysophosphatidic Acid Promotes Thrombus Stability by Inducing Rapid Formation of Neutrophil Extracellular Traps via a Peptidylarginine Deiminase 4-Dependent Pathway: A New Mechanism of Thrombosis

R. Peng¹, T. Li¹, F. Wang¹, L. Hua¹, S. Liu¹, J. Pei¹, Z. Han¹, S. Pei¹, Z. Zhao², X. Jiang³, X. Chen¹