ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1745

NAADP/SERCA3-Dependent Ca2+ Stores Pathway Specifically Controls Early Autocrine ADP Secretion Potentiating Platelet Activation

M. Feng¹, Z. Elaïb¹, D. Borgel¹, C. Denis¹, F. Adam¹, M. Bryckaert¹, J.-P. Rosa¹, R. Bobe²
Abstract Number: PB1756

NADPH Oxidase 1 and Protein Disulphide Isomerase Synergize to Modulate Platelet Function

R. Gaspar¹, G. Little¹, T. Sage¹, G. Pula², J. Gibbins¹
Abstract Number: PB2490

National Survey about Management of Venous Thromboembolism (VTE) Associated with Pregnancy / Puerperium or Oral Contraceptives in Uruguay

V. Mérola, V. Zubiaurre, S. Grille, A.C. Pizzarossa, L. Nicassio, M. Lorenzo, M.N. Spangenberg, G. Dos Santos, L. Díaz, C. Guillermo, R. Martínez
Abstract Number: PB0739

Nattokinase – Inhibition of Melanin Synthesis (Whitening Effect)

H. Sumi¹, Y. Yanagisawa², S. Naito¹, C. Yatagai¹
Abstract Number: PB0173

Natural Anticoagulant from Peony

M. Lyapina¹, E. Maystrenko², M. Kalugina¹
Abstract Number: PB0170

Natural Compounds as Anticoagulant Drug: A New Avenue for Improving Thrombosis Outcome

S. Sharma¹, I. Garg¹, T. Bhakuni², M.A. Jairajpuri², B. Kumar¹, M.Z. Asharf^1,3
Abstract Number: PB0508

Negative Efect of Pre Pre-Analytical Error Sources on the APTT Test

C. Delianu, L.L. Hurjui, M. Moscalu, C.C. Tarniceriu, I. Hurjui, O.-V. Badulescu, L. Foia
Abstract Number: PB1949

Neointimal Hyperplasia Regression using Lipid- Based Encapsulated Methotrexate Nanoparticles- Mediated Catheter- Based Low- Level Blue Laser Photodynamic Therapy

H. Mehrad¹, A. Foletti²
Abstract Number: OC 11.5

NETosis in Pregnancy: Role of Different Histones Subtypes

M. Fortier¹, L. Vincent¹, E. Mousty², C. Demattei³, M. Herzog⁴, G. Rommelaere⁴, E. Mercier^1,5,6, E. Nouvellon¹, V. Letouzey^2,7, S. Bouvier^1,5,6, J.-C. Gris^1,5,6
Abstract Number: PB0256

Neutralization of Osocimab-Induced Anticoagulation with Prothrombin Complex Concentrate, Activated Prothrombin Complex Concentrate and Recombinant Activated FVII in vitro

A. Buchmueller¹, A. Wilmen¹, V. Laux²
Abstract Number: PB1922

Neutrophil Activity in Patients with Antiphospholipid Syndrome-Related Thrombosis

B.M. Mazetto¹, B.W. Hounkpe², A.P.R. Santos¹, B. Jacintho¹, G.L.T.V. Mesquita¹, C.O. Vaz¹, J. Annichino-Bizzacchi², É. De Paula², F.L.A. Orsi^2,3
Abstract Number: PB0392

Neutrophil Extracellular Trap in Patients with Peritoneal Carcinomatosis of Several Origins

S. Mirshahi^1,2, I. Aldybiat¹, G. Contant², M. Pocard¹, J. Soria¹, M. Mirshahi¹
Abstract Number: PB2018

Neutrophil Extracellular Traps (Nets) Increase the Pro-Tumoral Properties of the Human Breast Cancer Cell Line, MCF7

K. Cardoso¹, V. Almeida¹, K. Bagri², M.-I. Rossi², C. Mermelstein², S. König², R. Monteiro¹
Abstract Number: OC 05.3

Neutrophil Extracellular Traps and Inflammasomes Form an Inflammatory Circuit Promoting Venous Thrombosis

J. Campos¹, T. Ponomaryov¹, A. De Prendegast¹, A. Brill^1,2
Abstract Number: PB/CO08

Neutrophil Extracellular Traps Infiltrate Lung Vascular, Interstitial and Airway Compartments in Severe Covid-19

C. Oury¹, C. Radermecker², N. Detrembleur³, J. Guiot⁴, M. Henket⁴, C. D'Emal¹, C. Vanwinge⁵, D. Cataldo⁵, P. Delvenne³, T. Marichal²
Abstract Number: PB2005

Neutrophilic Extracellular Traps (NETs) Are a Subset of Smudge Cells Identifiable by Peripheral Smear Autoanalyzers

M. Reyes-Gil¹, D. Yin², K. Fedorov², M. Barouqa¹, K. Ikemura¹, M. Kushnir², H. Billett²
Abstract Number: PB1950

Neutrophils and Neutrophil Extracellular Traps (NETs) Can Promote Clotting and Impact Clot Structure in a Distinctive Manner

Y. Shi¹, S.R. Baker², J.S. Gauer¹, H. Philippou¹, S.D. Connell³, R.A.S. Ariens¹
Abstract Number: PB0452

Neutrophils Extracellular Traps (NETs) Contribute to Thrombin Generation (TG) Potential in Patients with Essential Thrombocythemia (ET)

S. Gamba¹, C.J. Tartari¹, M. Herre², M. Marchetti¹, L. Russo¹, C. Verzeroli¹, C. Giaccherini¹, A. Vignoli¹, A.K. Olsson², A. Falanga^1,3
Abstract Number: PB1447

New Clues to GNE Gene Role in the Pathogenesis of Inherited Thrombocytopenias

I. Persico¹, R. Bottega², F. Faletra², T. Giangregorio², P. D'Adamo^1,2, A.M. Bianco², A. Pastore³, P. Grotto⁴, M. Gabelli⁵, A. Biffi⁵, A. Burlina⁵, A. Marzollo⁵, A. Savoia^1,2
Abstract Number: PB1145

New Factor VIII Function-Mimetic Bispecific Antibodies Engineered from Emicizumab for Further Improving the Treatment of Hemophilia A

Y. Teranishi¹, T. Soeda², H. Koga³, K. Yamaguchi³, K. Kato³, A. Muto², K. Esaki³, M. Okuda¹, M. Sato³, N. Shibahara³, K. Yamaguchi³, T. Wakabayashi³, H. Shiraiwa², H. Konishi³, H. Kitamura³, T. Kitazawa³, T. Igawa^1,3
Abstract Number: PB0532

New Formula of “Ratio of Inhibited Thrombin Generation” Based on Modified Diluted Prothrombin Time Reagent Predicts Bleeding Risk of Patients with Low Coagulation Activity in Direct Oral Anticoagulants Therapy

O. Kumano¹, S. Suzuki², M. Yamazaki³, Y. An⁴, M. Yasaka⁵, M. Ieko⁶, the Japanese Study Group for the Effect Confirmation of Direct Oral Anticoagulants
Abstract Number: PB0336

New Hyperactive Factor IX Variants Identified with a Novel Computational Analysis

T. Daniel¹, J. Chau¹, V. Arruda^1,2, B. Samelson-Jones^1,2
Abstract Number: PB0211

New Peptide Inhibitors of Serine Proteases of the Blood Coagulation System

L. Mukhametova^1,2, E. Ivanova¹, R. Aisina¹, T. Voyushina³, N. Sokolenko³
Abstract Number: PB0021

New Rat Model of Ferric Chloride-induced Acute Coronary Artery Thrombosis for Pharmaceutical Treatment of Myocardial Infarction

C.-E. Laurent, É. Dupré, E. Demeule, D. Salvail
Abstract Number: PB0679

New Ready-to-Use Liquid Multiplatform Global Screening Assays with Extended Stabilities to Facilitate Laboratory Practice

M. Peyrafitte, C. Dunois, S. Molton, V. Villedieu, J. Amiral
Abstract Number: PB0816

Next Generation Sequencing Antibody Repertoire Analysis of Inhibitory Immune Response in Hemophilia A

W.D. Lees¹, E. Wozniak², P. Batty^2,3, C.A. Mein², A.J. Shepherd¹, D.P. Hart^2,3
Abstract Number: PB2175

No Agreement among Risk Prediction Scores for Venous Thromboembolism in Cancer Patients: A Prospective Cohort Study

M. Evelyn Alves de Almeida, G. da Silva Souza Gois, T. Ramires Rodrigues Alencar, S. Aparecida de Lima Montalvão, B. Moraes Martinelli, I. Macedo Toni, J. Barreto Carvalheira, M. Etchebehere, N. Adami Andreollo, J. Cesar Teixeira, J. Maria Annichino-Bizzacchi, ADVENTH Cancer Investigators
Abstract Number: PB2119

No Impact of Previous Venous Thromboembolism on the Survival of Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation for Refractory Lymphoma

J. Rupa-Matysek, M. Joks, M. Matuszak, A. Łojko-Dankowska, L. Gil
Abstract Number: PB1071

No Peak of New-onset Inhibitors in the Aging Hemophilia Population: An International, Retrospective, Observational, Cohort Study of New Inhibitors in People with Hemophilia Aged 40 Years and Older (the NIAP Study)

J. Astermark¹, M. Carvalho², P. De Moerloose³, R. D'Oiron⁴, G. Dolan⁵, P. Fontana³, C. Hermans⁶, P.A. Holme⁷, O. Katsarou⁸, G. Kenet⁹, R. Klamroth¹⁰, A. Lubetsky⁹, M.E. Mancuso¹¹, N. Marquardt¹², R. Núñez¹³, I. Pabinger-Fasching¹⁴, R. Schutgens¹⁵, C. Tait¹⁶, ADVANCE Working Group
Abstract Number: PB0936

No Relapse in Patients with Previous Inhibitors Switched to rFVIIIFc in Ongoing Observational Phase 4 Studies

J. Oldenburg¹, C. Heller², H. Malmström³, B. Winding³, S. Lethagen^3,4
Abstract Number: PB0855

Non-Human Glycans Regulate FVIII Inhibitor Formation in Mice

C. Arthur¹, P. Zerra^1,2, J. Wang¹, S. Shin¹, C. Doering^1,2, P. Lollar^1,2, S. Meeks^1,2, S. Stowell¹
Abstract Number: PB0130

Non-Invasive Optical in vivo Imaging Reveals Tumor-Derived Prothrombin with a Functional Role in Hemostasis and Tumor Progression

L.K. Schott^1,2,3, L. Pruschinski^1,2,3, S. Khokar^1,2,3, L. Eder^1,2,3, K. Muhammad^1,2,3, S. Tokalov^1,2,3, J. Satrapa^1,2,3, M. Klein⁴, K. Lackner³, S. Danckwardt^1,2,3
Abstract Number: PB2047

Non-Persistence to Direct Oral Anticoagulants and Risk of Thromboembolic Stroke among Patients with Non-Valvular Atrial Fibrillation: A Dutch Nationwide Cohort Study

M.M.A. Toorop¹, Q. Chen¹, V. Tichelaar², S.C. Cannegieter¹, W.M. Lijfering¹
Abstract Number: PB2111

Non-Randomized Patient Outcomes. ADAM-VTE Registry Analysis

E. Wysokinska¹, D. Houghton², D. Hodge¹, A. Ashrani³, W. Wysokinski², C. Loprinzi⁴, R. McBane²
Abstract Number: PB1736

Non-redundant Roles of Platelet Glycoprotein VI and IIb/IIIa via Syk Kinase in Fibrin-dependent Thrombus Shielding under Flow

G. Perrella^1,2, J. Huang^1,3, I. Provenzale¹, F. Swieringa¹, F.C.J.I. Heubel-Moenen⁴, R.W. Farndale⁵, M. Roest⁶, M. Thomas², R.A.S. Ariëns^1,7, M. Jandrot-Perrus⁸, S.P. Watson^1,2,9, P.E.J. van der Meijden¹, J.W.M. Heemskerk¹
Abstract Number: PB1005

Non-Sever Hemophilia Is Not Benign? – Insights from the PROBE Study

C. Chai-Adisaksopha¹, R. Curtis², N. Frick³, M. Nichol⁴, D. Noone⁵, F. Germini⁶, B. O'Mahony⁵, D. Page⁷, J. Stonebraker⁸, M. Skinner^6,9, A. Iorio^10,11, PROBE
Abstract Number: PB2046

Non-Valvular Atrial Fibrillation Patients Anticoagulated with Rivaroxaban Compared with Warfarin Exhibit Attenuated Plasma Platelet Activation Markers and Pro-Inflammatory Extracellular Vesicle Proteomic Signatures

L. Weiss¹, P.B. Szklanna¹, W. Uhrig¹, K. Ewins², J. Keaney^3,4, T. Prendiville², S. Kelliher², C. Hanley², Á. Lennon², E. Dillion⁵, A. Blanco⁶, S. Murphy^3,7,8, F. Ní Áinle^1,3,9, P.B. Maguire^1,10
Abstract Number: PB0200

Nontoxic Polyphosphate Inhibitor that Reduces Thrombosis without Increased Bleeding

S.A. Smith¹, C.C. La^2,3, M.D.G. Jaraquemada-Peláez³, S. Abbina^2,4, L.A. Creagh⁵, R. Adili⁶, M. Holinstat⁶, C.A. Haynes⁵, J.H. Morrissey¹, J.N. Kizhakkedathu^2,3,4
Abstract Number: PB1979

Novel Anti-Inflammatory Network: The Phosphatase Domain of Soluble Epoxide Hydrolase Mediates the regulation of β2 Adrenergic Receptor-IL-6 Signaling and Vascular Endothelial Activation

E. Suzuki, M. Nakano, H. Kinoshita, K. Hasumi
Abstract Number: PB0136

Novel Mouse Model for Studying Hemostatic Function of Human Platelets

D.S. Paul^1,2, W. Bergmeier^1,2
Abstract Number: PB0149

Novel Oral Anticoagulants Do Not Expand Haematoma Volume in a Intracerebral Hemorrhage Model in Rats

J. Ferreira¹, R. Fonseca², P. Coelho³, P. Rosado², P. Mourao¹
Abstract Number: PB1694

Novel Role for Intracellular Lipases in Platelets

M. Goeritzer¹, S. Schlager¹, N. Vujic¹, S. Rainer¹, D. Kolb¹, M. Mussbacher², A. Schlagenhauf¹, H. Haidl¹, C.T. Madreiter-Sokolowski¹, W.F. Graier¹, D. Kratky¹
Abstract Number: PB1854

Novel Urokinase-derived Peptides Inhibiting the Pro-tumoral Activity of Cancer-associated Fibroblasts

M.P. Stoppelli¹, S. Belli¹, P. Franco¹, A. De Vincenzo¹, F. Iommelli¹, S. Del Vecchio², L. Telesca¹, P. Grieco³, A. Carotenuto³