ISTH 2020 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1514

Targeted High-throughput Sequencing for Genetic Classification of Patients with Inherited Platelet Disorders

H. Schulze¹, G. Manukjan¹, E. Klopocki², O. Andres¹, GPOH/GTH Study Group 'ThromKid-Plus' on Inherited Platelet Disorders
Abstract Number: PB0755

Targeted Measurement of Plasmin Kinetics on the Activated Platelet Membrane

M. Simpson, B. Veuskens, C.S. Whyte, N.J. Mutch
Abstract Number: PB1733

Targeting of a Conserved Epitope in Mouse and Human GPVI Differently Affects Receptor Function and in vivo Depletion

S. Navarro^1,2, H. Brown^1,2, M. Kuijpers³, J. Heemskerk³, D. Stegner¹, B. Nieswandt^1,2
Abstract Number: PB1661

Targeting the Chemokine Receptor CXCR7 Favours an Anti-thrombotic Platelet Lipidome and Regulates Thromboinflammatory Functions

L. Pezl¹, M. Cebo², K. Althaus¹, D. Rath³, M. Lämmerhofer², M. Gawaz³, T. Bakchoul¹, M. Chatterjee³
Abstract Number: PB0098

Temporary Hypofibrinogenemia in Reversible Cerebral Vasoconstriction Syndrome (SRVC) Associated a Cannabis Overdose

S. Herrero¹, G. Carvalho², J. Hernández², B. Merchán¹
Abstract Number: PB2263

Ten Years of Venous Thromboembolism Events in a Large Teaching Hospital: Changing Patterns of Disease

H. Rowswell, T. Nokes
Abstract Number: PB0827

Testing the Impact of Recombinant von Willebrand Factor and Recombinant Factor VIII on Osteoclastogenesis

H. Haidl, S. Pohl, T. Strini, M. Tischitz, S. Gallistl, A. Schlagenhauf
Abstract Number: PB1896

Tetra Positive Thrombotic Antiphospholipid Syndrome: Major Contribution of Anti Phosphatidyl-Serine/Prothrombin Antibodies to Lupus Anticoagulant Activity

M. Cattini, E. Bison, E. Pontara, C.-Y. Cheng, G. Denas, V. Pengo
Abstract Number: PB1734

Tetraspanin CD9 Regulates GPIIb-IIIa-Mediated Platelet Function: Identification of Unique Protein Interactomes

J. Kotha¹, X. Zhai¹, M. Herr^1,2, S. Hill³, L. Jennings¹
Abstract Number: OC 10.2

The ALK Rearrangement is a Major Risk Factor for Venous and Arterial Thrombosis in Non-Small Cell Lung Cancer

H. Al-Samkari^1,2, O. Leiva^2,3, I. Dagogo-Jack^2,4, A. Shaw^2,4, P. Bendapudi^1,2, J. Connors^2,5
Abstract Number: PB1594

The VWF Variant D1472H Affects VWF Binding to Ristocetin in vitro in the Platelet Agglutination Assay but Not with Latex Particles (HemosIL® Acustar VWF:GpIbR): The Usefulness to Change Practices to Avoid VWD Genotyping

F. Lassalle¹, E. Jeanpierre¹, C. Zawadzki¹, P. Boisseau², A. Veyradier³, A. Rauch¹, J. Goudemand¹, S. Susen¹
Abstract Number: PB0985

The 2-Years Successful Experience of Immune Tolerance Induction (ITI) with High-Purity Human FVIII/ von Willebrand Factor (vWF) in Hemophilia A Patients

M. Savitri, A. Ashariati
Abstract Number: PB1140

The 2020 World Federation of Hemophilia Guidelines for the Management of Hemophilia

A. Srivastava¹, G. Pierce², S. Zelman Lewis³, D. Coffin², D. Hum⁴
Abstract Number: PB1607

The Ablation of Collagen VI Leads to the Release of Platelets with Altered Functions

V. Abbonante^1,2, C.A. Di Buduo^1,2, M. Battiston³, M. Chrisam⁴, L. Sereni⁵, C. Semplicini⁶, A. Villa^5,7, E. Pegoraro⁶, P. Braghetta⁴, L. De Marco³, P. Bonaldo⁴, A. Balduini^1,2
Abstract Number: PB/CO14

The Acquired Coagulopathy of COVID-19

F. Peyvandi^1,2, A. Artoni², C. Novembrino², S. Aliberti^1,3, M. Panigada⁴, M. Boscarino², R. Gualtierotti^1,2, R. Palla¹, F. Rossi², I. Martinelli², G. Grasselli^1,4, F. Blasi^1,3, A. Tripodi²
Abstract Number: PB2160

The Activated Coagulation Factor X (FXa) Directly Stimulates Colorectal Cancer Cell Migration and Proliferation – Characterizing the Underlying Molecular Mechanisms

U. Meyer, S. Polster, E. Moritz, B.H. Rauch
Abstract Number: PB1645

The Active Recruitment of Red Blood Cells to Activated Platelets via CD36 and FasR Is Crucial for Arterial Thrombus Formation

K. Krott, M. Elvers
Abstract Number: PB2363

The Added Benefit of Mechanical Compression to Prevent VTE after Hip or Knee Arthroplasty: Post-Hoc Analysis of the EPCATII Study

C.J.M. Green, S. Shivakumar, C. Theriault, S. Doucette, S. Pleasance, D. Anderson
Abstract Number: PB1129

The Age Dependent Effects of Female Sex on Platelet Behavior after Injury

Z. Matthay, M. Patel, A. Fields, B. Nunez-Garcia, E. Ross, J. Park, R. Callcut, L. Kornblith
Abstract Number: PB0854

The Annual Global Survey Continues to Close the Gap in Data Collection of Bleeding Disorders

E. Tootoonchian¹, J. Stonebraker², A. Iorio³, V. Byams⁴, M. El Ekiaby⁵, M. Makris⁶, J. O'Hara⁷, H. Chambost⁸, A. Weill¹, G. Pierce¹, A. Baumann¹, D. Coffin¹
Abstract Number: PB1985

The Anti-Inflammatory Effects Of 3´-Hydroxygenkwanin from Aquilaria sinensis in Human Neutrophils

H.R. Liao^1,2, J.-J. Chen³, S.-Y. Wang⁴
Abstract Number: PB0229

The Anticoagulant Effect of Protamine – A Stabilizer of the Factor V Procofactor State

T. Petrillo¹, B.C. Remick¹, R.M. Camire^1,2
Abstract Number: PB0064

The Antidepressant Drug Desipramine Prevents Arterial Thrombosis in a Mouse Model Carrying the Human BDNFVal66Met Polymorphism

L. Sandrini¹, P. Amadio¹, A. Ieraci², A. Malara^3,4, J.P. Werba¹, P.M. Soprano^3,4, A. Balduini^3,4, M. Zarà¹, A. Bonomi¹, F. Veglia¹, G. Colombo¹, F.S. Lee⁵, E. Tremoli¹, S.S. Barbieri¹
Abstract Number: PB1961

The Antioxidant and Antiinflammatory Effect of Synbiotic Beverage from Soybean Water Kerfir on Aortic Tissue of Hyperlipidemic Rats Model

M. Afifudin¹, E. Marfianti²
Abstract Number: PB0199

The Antiplasmin Activity of the Kunitz Protease Inhibitor Domain of Protease Nexin 2 Affects Thrombolysis and Thrombosis in Mouse Models

L. Eltringham-Smith¹, V. Bhakta¹, W. Sheffield^1,2
Abstract Number: PB2358

The Application of the Lymphoma International Prognostic Index (IPI) to Predict Venous Thromboembolic Events (VTE) in Patients with Diffuse Large B-Cell Lymphoma (DLBL)

H. Abdel-Razeq, M. Ma'koseh, R. Mansour, R. Amarin, A. Abu Fara, M. Manassra, M. Alrwashdeh, R. Bater
Abstract Number: PB2366

The Application of the Original and a Modified Version of the ThroLy Risk Assessment Model (RAM) to Predict Venous Thromboembolic Events (VTE) in Patients with Diffuse Large B-Cell Lymphoma (DLBL)

H. Abdel-Razeq, M. Ma'koseh, A. Mansour, R. Amarin, A. Abu Fara, R. Bater, M. Manassra, M. Alrwashdeh, M. Zmaily, M. Almomani
Abstract Number: PB1808

The Assessment of Platelet Membrane Alteration in Patients with Chronic Myeloproliferative Neoplasms

V. Popov¹, C.O. Matei², M. Andreescu³, M.G. Moisescu², T. Savopol²
Abstract Number: PB2081

The Association between Neighborhood Socioeconomic Status, Geographical Area and Non-persistence to Using DOACs

N. van Rein^1,2, G.D. Zielinkski¹, E.M. Ras¹, M. Teichert³, F.A. Klok⁴, F.R. Rosendaal¹, F.J.M. van der Meer⁴, M.V. Huisman⁴, S.C. Cannegieter^1,4, W.M. Lijfering¹
Abstract Number: OC 13.4

The Association between Platelet Count and Perioperative Bleeding Complication in a Cohort of Cirrhotic Patients Undergoing Surgical Excision of Hepatocellular Carcinoma

V. Ronca¹, G. Podda¹, R. Santambrogio², M. Barabino², E. Opocher², P.M. Battezzati³, M. Zuin³, M. Cattaneo¹
Abstract Number: PB2313

The Association of BMI and Waist Circumference Improves the Prediction of VTE Risk as Compared to BMI Alone

L.M. Caiano¹, W. Ageno¹, S. Costanzo², T. Panzera², M.P. Donadini¹, M.B. Donati², L. Iacoviello²
Abstract Number: PB0277

The Association of Prothrombin Complex Concentrates with Transfusion Requirement and Postoperative Outcomes in Cardiac Surgery: A Post-Hoc Analysis of the FIBRES Randomized Controlled Trial

J. Bartoszko¹, K. Karkouti², J. Callum^3,4, on Behalf of the FIBRES Study Investigators
Abstract Number: PB2557

The Attitudes of Haemophilia Carriers towards Prenatal Diagnosis and Mode of Delivery

O. Turan, J. Davies, D. Pollard, M. Musarara, R. Abdul-Kadir
Abstract Number: PB0593

The Basic Evaluation of Light Transmission Platelet Aggregation Method on an Automated Coagulation Analyzer CN-6000

M. Egashira¹, M. Kono², K. Nakajima², T. Sakayori¹
Abstract Number: PB0531

The Basic Evaluation of the Newly Developing Modified Diluted Prothrombin Time Reagent for Direct Oral Anticoagulants Measurements

O. Kumano¹, S. Suzuki², M. Yamazaki³, Y. An⁴, M. Yasaka⁵, M. Ieko⁶, the Japanese Study Group for the Effect Confirmation of Direct Oral Anticoagulants
Abstract Number: PB0501

The CDC Hemophilia A Mutation Project (CHAMP) F8 Mutation List: 2020 Update

A.B. Payne, C.H. Miller, C.J. Bean
Abstract Number: PB1886

The Changing Face of Thrombotic Thrombocytopenic Purpura (TTP) in South Africa in the Human Immunodeficiency Virus (HIV) Era

S. Louw^1,2, E.S. Mayne^2,3, M. Meiring^4,5, A. Mmakgabu⁴, R. Gounden^1,2
Abstract Number: PB2331

The Characteristics of Patients with Isolated Superficial Vein Thrombosis of the Legs, their Follow-up and Outcomes

J. Hirmerová¹, J. Seidlerova¹, I. Subrt², Z. Hajsmanova³
Abstract Number: PB0982

The CHiC Study: The Canadian Hemophilia Carriers Study – Preliminary Results

K. de Repentigny¹, M. Hinds¹, J. Grabell¹, A. Keepanasseril², A. Iorio³, N. Rydz⁴, S. Jackson⁵, S. Robinson⁶, L. Sun⁷, M. Belletrutti⁷, P. James¹
Abstract Number: PB1022

The Clinical Phenotype of Patients with Non-severe Hemophilia A and B

A.-F. Zwagemaker¹, F.R. Kloosterman¹, E.A.M. Beckers², J.G. van der Bom^3,4, S. Boyce⁵, P.P. Brons⁶, P.W. Collins⁷, M. Coppens⁸, S.C. Gouw¹, C. Harrison⁹, F.W.G. Leebeek¹⁰, F.J.M. van der Meer¹¹, K. Meijer¹², L. Nieuwenhuizen¹³, K. Fijnvandraat^1,14, DYNAMO Study Group
Abstract Number: PB0974

The Clinical Picture in Romanian Patients with Severe Forms of Hemophilia A: What Role did the Intron 22 Inversion and Age Play?

M.-A. Gaman^1,2, M. Brinza³, V. Uscatescu³, A. Diaconu³, A. Grigore⁴, M. Dragomir³, D. Coriu¹
Abstract Number: PB0082

The Clinical Predictors of Coronary Artery Disease: A Population-based Study from Developing Country

M.F. Addai¹, A.B. Setyani², F. Ramdhitabudi³, J.H. Haposan⁴, A.K.T. Haruni⁵, A.M. Soesanto⁶
Abstract Number: PB0284

The Comparison of Critical Care Instrument CoaguChek® Pro II with Coagulation Analyzers Sysmex CS-5100 and Cobas t 511

M. Pulcer^1,2, J. Gumulec², L. Recova², S. Kolarova², Z. Svagera¹, D. Stejskal^1,2
Abstract Number: PB1562

The Compound Heterozygosity with Two in Cis Mutations p.R924Q and p.A2178S in the D’D3 and D4 Domain Causes a Type 2B-Like von Willebrand Disease

S. Lancellotti¹, M. Sacco², M. Tardugno², E. De Candia², L. Di Gennaro³, M. Basso¹, B. Giusti⁴, G. Castaman⁵, R. De Cristofaro^2,3
Abstract Number: PB1491

The contribution of flow cytometry in the diagnosis of inherited thrombocytopathies

H. Brouk, M. Rachi, A. Amireche, H. Ouelaa
Abstract Number: PB0891

The Current State of Biochemical Marker Research in Hemophilic Arthropathy: A Review

E.D.P. van Bergen¹, L.F.D. van Vulpen¹, R.E.G. Schutgens¹, S.C. Mastbergen², F.P.J.G. Lafeber²
Abstract Number: PB0379

The Diagnostic and Prognostic Role of Protein C and Padui Scale for Prediction of Lung Vessel Thrombosis in Patients with Community-Acquired Pneumonia

M. Krykhtina, K. Bielosludtseva, T. Pertseva
Abstract Number: PB0427

The Diagnostic Significance of Platelet-Derived Microparticles Quantification by Flow Cytometry in Egyptian Patients with Ischemic Heart Disease

N. Farouqe¹, M. Wahba¹, A. Saad¹, R. El-Gamal¹, Y. Elsakhawy¹, M. Farouk²
Abstract Number: PB0228

The Distribution of Hemophilia A-causing Genetic Variants by Race/Ethnicity and Association with Inhibitors among Enrollees in the Hemophilia Inhibitor Research Study (HIRS)

A.B. Payne¹, J. Driggers¹, D. Ellingsen¹, C. De Staercke¹, C.H. Miller¹, B. Boylan¹, F.M. Bethea¹, J.M. Soucie¹, U.M. Reiss², G. Young³, C.J. Bean¹, Hemophilia Inhibitor Research Study Investigators
Abstract Number: PB2133

The Downregulation of Mucin1 Initiates Aberrant Calcium Signalling Pathways of Cancer Cells which Are Partly Responsible for the Procoagulant Phenotype

Y. Chen, M. Scully
Abstract Number: PB/CO16

The Effect of Anticoagulation on Mortality in COVID-19 Patients: The Drug, the Dose, and the D-Dimer

H. Billett¹, M. Reyes Gil², J. Szymanski², K. Ikemura², L. Stahl³, Y. Lo⁴, S. Rahman¹, J. Gonzalez Lugo¹, M. Kushnir¹, M. Barouqa², L. Golestaneh⁵, E. Bellin⁴
Abstract Number: PB1389

The Effect of Aspirin in Tumor Growth of Obese Mice Involving Inhibition of Metabolism

J.-D. Wang¹, C.-J. Chen², W.-Y. Chen³, J.-R. Li⁴, S.-Y. Lin⁴, Y.-Y. Wang⁵
Abstract Number: PB1138

The Effect of Bypassing Agents in Combination with Emicizumab-treatment

N.H. Schultz^1,2,3, H. Glosli^4,5, S. Bjørnsen⁶, P.A. Holme^1,2,7
Abstract Number: PB1709

The Effect of Ceramic Materials on Platelet Aggregation

A.D. Nikanorova¹, I.P. Antropova^2,3, M.V. Gilev^2,3, M.U. Izmodenova^2,3, S.L. Khatsko¹, I.M. Petrova¹
Abstract Number: PB0652

The Effect of DOAC-Stop^® on Several Oral and Parenteral Anticoagulants

N. Riva¹, K. Vella², K. Hickey³, P. Gatt⁴, C. Grima⁴, D. Zammit², S. Kitchen³, M. Makris³, W. Ageno⁵, A. Gatt^1,2
Abstract Number: PB0629

The Effect of Haemolysis in Patient Samples on Coagulation Tests Performed on ACL TOP 550

K. Hickey, A. Woolley, S. Kitchen
Abstract Number: PB1641

The Effect of IL-6-Primed Platelets on ADAMTS13-Mediated Clearance of Platelet-Bearing ULVWF and its Mechanism

H.-J. Kim¹, Y. Song¹, J.-F. Dong², H.-I. Jung³, J. Song¹
Abstract Number: PB1880

The Effect of Liver Transplantation on ADAMTS13 Activity and Antigen Levels

T. Falter¹, F. Häuser¹, F. Hofsaess¹, L. Greulich², M. Sprinzl³, K. Lackner¹, I. Scharrer⁴, B. Lämmle^4,5,6, J. Mittler⁷
Abstract Number: PB1401

The Effect of Plasma Fibrinogen Level on Predictive Value of VerifyNow P2Y12 Assay Results in Patients Undergoing Percutaneous Coronary Interventions

A. Dobrovolsky¹, P. Laguta¹, E. Titaeva¹, A. Komarov¹, E. Novikova¹, E. Guskova¹, E. Yarovaya², E. Panchenko¹
Abstract Number: PB2476

The Effect of Postoperative Analgesia on the Hemostatic System in Gerontological Patients with Multiple Trauma

Y. Volkova, K. Mikhnevich, M. Dolzhenko
Abstract Number: PB0380

The Effect of Protein C on Various Links of Hemostasis

A. Makhmudova, I. Berger, L. Ashurova, N. Juraeva
Abstract Number: PB0524

The Effect of RBCs on Different Platelet Count Enumeration Methods in Patients with Hemoglobinopathies

R. Shekhar¹, S. Pai², S. V¹, V. Bhat²
Abstract Number: PB2466

The Effect of rs4148738 Polymorphism of ABCB1 on the Plasma Concentrations of Direct Oral Anticoagulants and Bleeding an Thromboembolic Complications

B. Cosmi¹, L. Salomone¹, M. Cini², G. Guazzaloca¹, C. Legnani²
Abstract Number: PB0765

The Effect of the Fibrino(geno)lytic Enzymes from Tissues of Antarctic Hydrobionts on Hemostasis

N. Raksha, O. Savchuk, L. Ostapchenko
Abstract Number: PB0587

The Effect of trough Dabigatran Plasma Concentration on Thrombin Generation

M. Milic^1,2, J. Stanfel¹, K. Paradinovic¹, V. Seric¹
Abstract Number: PB1710

The Effect of γ-Irradiation at a Dose of 1 Gy on Calcium Metabolism in Rat Platelets

V. Bichan¹, V. Parkhimovich², K. Bulanova²
Abstract Number: PB0727

The Effects of (Patho)Physiological Fibrinogen γ’ Levels on Static and Dynamic Clot Formation

F. Macrae¹, F. Swieringa², M. Pieters³, J. Heemskerk², R. Ariëns¹
Abstract Number: PB0391

The Effects of Acids on Whole Blood Coagulation is Depended on the Type of Acid and Concentration as Assessed by Thromboelastography (TEG)

G. Ogweno¹, B. Chege², P. Waweru³
Abstract Number: PB1651

The Effects of E.coli Lipopolysaccharides on Platelet Function Are Limited to Re-Sensitization

A. Martyanov^1,2,3, A. Maiorov¹, A. Filkova^1,2, A. Ryabukh², M. Panteleev^1,2, A. Sveshnikova^1,4
Abstract Number: PB0596

The Effects of EDTA as an Anticoagulant and Delayed Processing on the Measurement of Plasma VWF Antigen

M.C. Sims^1,2,3, F. Moenen⁴, R. Wetzels⁵, R. van Oerle⁵, M. Laffan^2,6, S. Shapiro², W.H. Ouwehand^1,3,7, M. Frontini^1,3,7, Y. Henskens⁵, NIHR BioResource
Abstract Number: PB1969

The Effects of Hypoxia on Activation of Endothelial Cells

C. Ullsten-Wahlund, J.-B. Hansen, O. Snir
Abstract Number: PB1691

The Effects of Platelet Agonists and Priming on Platelet Populations

A. Veninga¹, C.C.F.M.J. Baaten², B.M.E. Tullemans¹, M.J.E. Kuijpers¹, J.W.M. Heemskerk¹, P.E.J. van der Meijden¹
Abstract Number: PB0109

The Epinephrine-induced Platelet Aggregation Changes in Arterial Hypertension of Very High Risk

E. Shorikov¹, D. Shorikova¹, P. Shorikov², O. Khukhlina¹
Abstract Number: PB/LB04

The eTHINK Study: Cognitive and Behavioral Outcomes in Children with Hemophilia

C. Mrakotsky¹, C. Buranahirun², D.L. Cooper³, S.E. Croteau¹, M. Greybels⁴, C. Hannemann⁵, M. Rajpurkar⁶, K.A. Shapiro⁷, G.N. Wilkening⁸, P. Ventola⁹, K.S. Walsh¹⁰, on behalf of the eTHINK Study Group
Abstract Number: PB0926

The Experience of Orthopedic Surgeries in Ukrainian Hemophilia Patients with Inhibitor

Y. Kashpurenko¹, K. Vilchevska¹, I. Bakhchyvandzhy¹, V. Vitiaz²
Abstract Number: PB1188

The F7 p.Val22Ile Missense Mutation Affects Splicing and Can Be Counteracted by a Compensatory U1snRNA

P. Ferraresi¹, L. Rizzotto^1,2, A. Branchini¹, M. Baroni¹, D. Balestra¹, F. Bernardi¹, F. Pagani³, M. Pinotti¹
Abstract Number: PB0776

The FARES Study: A Multicenter, Randomized, Active-Control, Pragmatic, Phase 2 Pilot Study Comparing Prothrombin Complex Concentrate versus Frozen Plasma in Bleeding Adult Cardiac Surgical Patients

K. Karkouti¹, J. Callum²
Abstract Number: PB1774

The Fc and C1/C2 Domains of Recombinant Factor VIII Fc Fusion Protein Engage Monocytes in an FcgammaRII-Dependent Manner to Reduce Their Differentiation Potential into Osteoclasts

S. Duan, K. Kis-Toth, G. Rajani, R. Peters, J. Salas
Abstract Number: PB0969

The Feasibility of Teaching Handheld Ultrasound (HHUS) for Home Use to Identify Bleeding in Hemophilia

B. Steiner, M. Krimmel, M. Ewert, S. Lynch, R. Kruse-Jarres
Abstract Number: PB0734

The Fibrinogen αC Region Is a Major Contributor to the Mechanical Strength of Fibrin Fibers

A. Daraei¹, N. Hudson², T. Dement², M. Guthold¹
Abstract Number: OC 05.1

The Fibronectin Type II Domain of Factor XII Prevents Inappropriate Zymogen Activation

C.C. Clark¹, Z.L.M. Hofman^1,2, W. Sanrattana¹, L. den Braven¹, S. de Maat¹, C. Maas¹
Abstract Number: PB0204

The FibWave, a New Sensitive and Relevant Tool for Analysing the fibrin Clot Formation: Comparison with the Calibrated Automated Thrombogram to Assess Direct Oral Anticoagulants

J. Evrard¹, L. Morimont^1,2, R. Siriez¹, J.-M. Dogné¹, J. Douxfils^1,2
Abstract Number: PB1288

The Frequencies of Thrombophilic DNA Polymorphisms in Children with Hemolytic Uremic Syndrome from the North-Western Region of Russia

E. Pankov¹, K. Papayan¹, N. Savenkova¹, S. Kapustin², L. Papayan²
Abstract Number: PB0486

The Functional Profiles of Platelets Collected from Blood Diversion Pouches and Apheresis Concentrates Are Comparable to the Ones from Platelets Isolated through Standard Methods

P. Davizon-Castillo¹, K. Kelly², M. Kelher³, M. Manco-Johnson⁴, C. Silliman⁵, L. Dumont²
Abstract Number: PB0718

The Glycan Structure Associated to Factor XIII Subunit B and its Functional Importance

B. Hurják¹, Z. Kovács², É. Katona¹, K. Pénzes¹, G. Haramura¹, F. Sadeghi¹, A. Shemirani¹, A. Guttman², L. Muszbek¹
Abstract Number: PB2016

The Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury

S. Ascher¹, E. Wilms¹, H. Formes¹, M. Müller¹, G. Pontarollo¹, F. Malinarich¹, K. Jurk¹, C. Reinhardt^1,2
Abstract Number: PB1000

The Haemophilia A Patients whose FVIII: C by Chromogenic Substrate Assay were Higher than by One-Stage Substrate Assay Showed Risk of Development of Haemophiliac Arthropathy Silently

N. Suzuki¹, N. Takahashi¹, A. Suzuki², S. Tamura³, S. Suzuki³, Y. Hattori³, M. Kakihara³, M. Ogawa⁴, T. Kanematsu², T. Kojima⁴, T. Kojima³, H. Kiyoi⁴, N. Ishiguro⁴, T. Matsushita²
Abstract Number: PB1046

The Health Status of Older Patients with Hemophilia in the Netherlands

S. Hassan¹, E.C. van Balen¹, C. Smit¹, E.P. Mauser-Bunschoten², L.F.D. van Vulpen², J. Eikenboom³, E.A.M. Beckers⁴, L. Hooimeijer⁵, P.F. Ypma⁶, L. Nieuwenhuizen⁷, M. Coppens⁸, S.E.M. Schols^9,10, F.W.G. Leebeek¹¹, M.H.E. Driessens¹², F.R. Rosendaal¹, J.G. van der Bom^1,13, S.C. Gouw^1,14
Abstract Number: PB1576

The Homozygous Variant p.Gln1311* in Exon 28 of VWF Is Causing Type 3 von Willebrand Disease and Is at High Risk of Allo-Immunisation

F. Lassalle¹, C. Zawadzki¹, P. Boisseau², E. Jeanpierre¹, A. Rauch¹, C. Paris¹, A. Hochart¹, Y. Repesse³, A. Veyradier⁴, A. Harroche⁵, C. Biron-Andréani⁶, C. Falaise⁷, J. Goudemand¹, S. Susen¹
Abstract Number: PB2422

The Impact of an Educational Intervention in Patients with Atrial Fibrillation Treated with Warfarin

J.M. Costa¹, M.S. Marcolino², H.C. Torres³, R.P. Souza⁴, M.F.S. Praxedes⁵, H.C. Barbosa⁶, S.D.S. Barros¹, A.C. Viegas¹, D.V. Nascimento¹, C.B. Ferreira¹, N.S. Antunes⁷, A.C.R. Silva¹, D.D. Ribeiro⁷, M.A.P. Martins¹
Abstract Number: PB2344

The Impact of Body Mass Index (BMI) Dynamics on the Risk of Venous Thromboembolism Recurrence (VTE)

L. Padrnos¹, T. Petterson², K. Bailey², K. Lackore², A. Ashrani³
Abstract Number: PB2542

The Impact of Hydroxychloroquine on the Prevention of Severe Preeclampsia in Patients with Obstetric Anti-Phospholipid Syndrome

F. Aranda¹, J.O. Latino², S. Udry¹, S. Perés¹, D.S. Fernández Romero², G. de Larrañaga¹
Abstract Number: PB1010

The Impact of Physical Activity on the Pharmacokinetics of Factor VIII / IX in a Cohort of Pediatric Patients with Hemophilia A / B in Pharmacological Prophylaxis

C. Pastore, G. Lassandro, A. Amoruso, V.V. Palmieri, V. Palladino, P. Giordano
Abstract Number: PB2084

The Impact of Soluble Thrombomodulin and Circulating miRNAs on Catheter Ablation in Patients with Atrial Fibrillation

F. Namino¹, M. Yamakuchi¹, Y. Iriki², Y. Ninomiya², H. Ichiki², R. Maenosono¹, I. Masamoto¹, M. Ohishi², T. Hashiguchi¹, I. Maruyama³
Abstract Number: PB2206

The Impact of Successful Ultrasound-Accelerated Catheter-Directed Thrombolysis on the Prevention of Post-Thrombotic Syndrome: A Post-Hoc Analysis of the CAVA-Trial

P. Notten^1,2, C. Arnoldussen^3,4, R. Brans³, A. de Smet⁵, L. Tick⁶, M. van de Poel⁷, O. Wikkeling⁸, L.-J. Vleming⁹, A. Koster¹⁰, K.-S. Jie¹¹, E. Jacobs¹², H. Ebben¹³, N. Planken¹⁴, C. Wittens¹⁵, H. ten Cate^2,16,17, A.J. ten Cate-Hoek^2,16,17
Abstract Number: PB0971

The Impact of Switching Previously Treated Patients (PTPs) to Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Reducing the Annualized Bleeding Rate (ABR): A Single Center Experience

O. Benítez, M. Suito, A. Cabirta, J.C. Juarez, M.F. Martinez, G. Robayo, E. Alvarez, C. Fernandez, N. Soto, R. Cardona, M. Gironella
Abstract Number: PB1569

The Impacts of Genetic Polymorphisms on the Von Willebrand Factor Level in Type 1 Von Willebrand Disease

Y.-C. Chen¹, C.-Y. Chang², S.-N. Cheng³, S.-H. Hu²
Abstract Number: PB0440

The Importance of Altered Symmetric Dimethylarginine Levels with Platelet Hyperreactivity in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

C. Eyileten¹, J. Jarosz-Popek¹, A. Soplinska¹, Z. Fitas¹, A. Nowak¹, L. Zareba¹, G. von Baumgarten¹, P. Czajka¹, D. Jakubik¹, J. Siller-Matula^1,2, M. Ufnal³, M. Postula¹
Abstract Number: PB2381

The Incidence of Venous Thromboembolism along with Adherence to Guideline in Major Orthopedic Surgery

H.G. Hwang¹, S.-M. Koo², Y.-K. Kim²
Abstract Number: PB2456

The Increasing Bleeding Risk from Drug-drug Interactions in Patients with Direct Oral Anticoagulants

S.-M. Bang¹, J.Y. Lee¹, I.-Y. Oh¹, J.-H. Lee¹, S.-Y. Kim², S.-S. Kwon², H.-J. Yang², Y.-K. Kim²
Abstract Number: PB1957

The Induction Strategies Administered in the Treatment of Multiple Myeloma Exhibit a Deleterious Effect on the Endothelium

J. Martinez-Sanchez^1,2,3, M. Palomo^1,2,3, S. Torramade-Moix², A.B. Moreno-Castaño², M. Rovira⁴, G. Gutiérrez-García⁴, F. Fernandez-Aviles⁴, G. Escolar², O. Penack^5,6,7, L. Rosiñol^4,8, E. Carreras^1,3, M. Diaz-Ricart^2,3
Abstract Number: PB2309

The Influence of Anemia on Clinical Outcomes in Venous Thromboembolism: Results from GARFIELD-VTE

S. Goto¹, A.G.G. Turpie², A.E. Farjat³, J.I. Weitz^2,4, S. Haas⁵, W. Ageno⁶, S.Z. Goldhaber⁷, P. Angchaisuksiri⁸, J. Dalsgaard Nielsen⁹, G. Kayani³, P. MacCallum^3,10, S. Schellong¹¹, H. Bounameaux¹², L.G. Mantovani^13,14, P. Prandoni¹⁵, A.K. Kakkar^3,16
Abstract Number: PB0756

The Influence of Prothrombin Complex Concentrates on Clot Stability

C.D. Garcia, P. Chowdary, M.R. Peralta, Z. Hanif, A. Riddell, P. Lawler, L. Dailani, C. Hamid
Abstract Number: PB1746

The Inhibitory Mechanism of Adiporon during Platelet Activation

X. Zhou, Z. Cheng, Y. Hu
Abstract Number: PB0132

The Initial Formation of a Transient Sub-Occlusive Mural Thrombus Appears to Protect Coagulation to Leave a Thin Platelet- and Fibrin-Rich Patch Covering the Site of Injury

A. Yakusheva^1,2,3, A. Megalinsky^2,4, C. Bourdon¹, N. Receveur¹, A. Eckly¹, A. Shibeko^2,3,4, B. Hechler¹, D. Nechipurenko^2,3,4, C. Gachet¹, F. Ataullakhanov^2,3,4, M. Panteleev^2,3,4, P. Mangin¹
Abstract Number: PB1703

The Iron Uptake Receptor Transferrin Receptor 1 (TfR1) Is Required for Proper Platelet and Megakaryocyte Function in Mice

T. Vögtle¹, A. Deuschel¹, L.I. Schober¹, A. Geier², H.M. Hermanns², A. Braun¹, B. Nieswandt¹
Abstract Number: PB0798

The ISTH DIC Score Predicts Outcome in Non-Septic Patients Admitted to a Cardiovascular Intensive Care Unit

J. Grafeneder¹, K.A. Krychtiuk², N. Buchtele³, G. Gelbenegger¹, M. Lenz², J. Wojta⁴, C. Schörgenhofer¹, G. Heinz², K. Huber⁵, C. Hengstenberg², B. Jilma¹, W. Speidl²
Abstract Number: PB0048

The Level of SPECAM-1 and von Willebrand Factor during the Supraventricular Arrhytmia Episodes in Patients with Arterial Hypertension

E. Shorikov¹, D. Shorikova¹, P. Shorikov²
Abstract Number: PB0767

The Mechanism of Antifibrinolytic Action of Anionic Polyamidoamine Dendrimers

R. Aisina¹, L. Mukhametova^1,2, E. Ivanova¹
Abstract Number: PB1518

The Method of Purification of von Willebrand Factor

N. Shurko¹, Т. Danysh¹, V. Novak²
Abstract Number: PB0263

The Misfolded Protein Glycated Albumin Activates the Contact System Leading to Plasma Kallikrein Activity But Not Intrinsic Coagulation

L. Hardy¹, S.L. Heal¹, E. Hethershaw¹, R. Foster², C. Longstaff³, T. Renne⁴, H. Philippou¹
Abstract Number: PB1125

The Need for Red Cell Support during Surgery in a Tertiary Care Hospital Is Associated to Pretransfusion Levels of FXIII and the Platelet Count

S. Listyo¹, E. Forrest ()², L. Graf¹, W. Korte¹
Abstract Number: PB0598

The Novel Prothrombin Time (MRX PT DOAC) Assay ‐ Can Be Used to Detect Interfering DOACs in Thrombophilia Investigation

L. Onelöv¹, M. Abelius¹, T. Lindahl²
Abstract Number: PB1123

The Obstetric Experience of Carriers of Haemophilia

O. Turan, D. Pollard, R. Abdul-Kadir
Abstract Number: PB0111

The Optimal Treatment of Atrial Fibrillation in Patients with Cancer

I. Tzoran, Y. Morgenstern, A. Elias, R. Hoffman, B. Brenner
Abstract Number: PB1027

The Parameters of Modified Clot Waveform Analysis Using the Plasmas of Hemophilia A Patients Treated with Emicizumab

N. Yamasaki¹, K. Kajihara², H. Nakagawa², M. Yokozaki³, T. Fujii¹
Abstract Number: PB0547

The PFA Results Are Affected by Low Number of Platelets, Low Hematocrit and High Proportion of Immature Platelets

P. Kessler¹, M. Smejkalova¹, P. Bradacova², J. Prokopova¹, J. Vagnerova¹, J. Ullrychova², H. Poul¹, M. Harudova¹, A. Vaskova², T. Kohoutek²
Abstract Number: PB1706

The Platelet Indices in Patients with Obesity in Najran Area, Saudi Arabia

O.M. Alshehri¹, M.A. Seoudi², K.A. Sahli³, M.M. Elkhawanky⁴
Abstract Number: PB0438

The Presence of Anti-Phosphatidylserine/Prothrombin Antibodies Enhance Differences in the Thrombin Generation Phenotype among Subjects with Lupus Anticoagulant Not Meeting Antiphospholipid Syndrome Criteria

D. Velasco-Rodríguez, R. Vidal Laso, A. García-Raso, I. Mahíllo Fernández, K. Guzmán-López, S. Martín Herrero, E. Jiménez Barral, M.D.C. Vegas-Sánchez, M.J. Martínez Becerra, J.M. Alonso-Domínguez, C. Blas López, R. de la Plaza, L.F. López Romero, D. Mínguez, A. García López, M.S. Sánchez Fernández, P. Llamas-Sillero
Abstract Number: PB2243

The Presence of Paraproteinaemia in Patients with Antiphospholipid Syndrome – A Single Centre Case Series

A. Doyle, K.A. Breen, B.J. Hunt
Abstract Number: PB1303

The Prevalence of Lupus Anticoagulant in Children and Adolescences Referred to the Reference Coagulation Laboratory of Iranian Blood Transfusion Organization

M. Mashkooli¹, M. Ahmadinejad², S. Jafari¹, T. Pakravan¹
Abstract Number: PB0117

The Prevalence of Peripheral Artery Disease in Hospitalized Patients with Heart Failure

C. Fantoni¹, N. Mumoli², W. Ageno³, M. Silingardi⁴, L. Bertù³, C. De Dionigi³, M. Giorgi-Pierfranceschi⁵, V. Gessi³, N. Laganà⁶, B. Petroboni⁵, F. Dentali³
Abstract Number: PB1351

The Prevalence, Risk Factors, and Bleeding Tendency of Thrombocytopenia in Patients with Hepatitis C Virus and Hepatitis B Virus Infection

C.-E. Huang^1,2, M.-C. Chen^1,3, C.-C. Chen^1,4, Y.-Y. Wu¹, S.-H. Huang^1,3, C.-C. Hsu¹, C.-P. Li¹
Abstract Number: PB2294

The Prognostic Role of Neutrophil to Lymphocyte Ratio (NLR) in Venous Thromboembolism and Related Mortality

M.F. Adda'i^1,2, A.B. Setyani³, J.H. Haposan², A.K.T. Haruni⁴
Abstract Number: PB0474

The Prognostic Role of Red Cell Distribution Width in Venous Thromboembolism and Related Mortality

M.F. Adda'i^1,2, A.B. Setyani³, J.H. Haposan², A.K.T. Haruni⁴, A.M. Soesanto⁵
Abstract Number: OC 14.3

The Proline-Rich Tyrosine Kinase Pyk2 Contributes to Venous Thrombosis

S. Momi¹, J. Canino², E. Falcinelli¹, G. Guglielmini¹, L. Galgano², M. Vismara³, G. Guidetti³, P. Gresele¹, M. Torti³, I. Canobbio³
Abstract Number: PB2033

The Protective Effects of PAR1-agonists – Thrombin, Activated Protein C and Peptide 9 in the Model of the Neuroinflammation in vitro

I. Babkina¹, L. Gorbacheva^1,2
Abstract Number: PB2232

The Prothrombin Belgrade Mutation Causing Antithrombin Resistance Does Not Affect Fibrin Clot Formation

S. Dunjic¹, M. Cumbo¹, I. Pruner², M. Gvozdenov¹, A. Taxiarchis², B. Tomic¹, J. Antovic^2,3, V. Djordjevic¹
Abstract Number: PB1903

The Prothrombin/MHC II Complexes on Cell-Surface of Monocytes Is the Antigenic Targets in Antiphospoholipid Syndrome

Y. Fujieda¹, N. Ohnishi¹, T. Sato¹, M. Kono¹, M. Kato¹, K. Oku¹, O. Amengual¹, H. Arase², T. Atsumi¹
Abstract Number: PB/CO03

The prothrombotic imbalance between VWF and ADAMTS13 in COVID-19

I. Mancini¹, L. Baronciani², A. Artoni², P. Colpani², M. Biganzoli², G. Cozzi², C. Novembrino², M. Boscolo², V. De Zan¹, S. Aliberti^1,3, M. Panigada⁴, G. Grasselli^1,4, F. Blasi^1,3, F. Peyvandi^1,2
Abstract Number: PB2472

The Psychosocial Impact of Venous Thromboembolism: An Exploratory Systematic Review and Narrative Synthesis

G. Saul¹, E. Gee¹, V. Speed¹, C. Jordan²
Abstract Number: PB1983

The R398w Gata-2 Variant Negatively Regulates E-Nos Activity: Possible Role in GATA2 Deficiency-associated Thrombosis

G. Purgatorio¹, V. Di Battista², E. Piselli¹, G. Guglielmini¹, F. Pellanera², C. Matteucci², E. Falcinelli¹, L. Bury¹, C. Mecucci², P. Gresele²
Abstract Number: PB1741

The Recombinant Disintegrins Jarastatin and Jararacin and their Inhibitory Activity on Platelet and Endothelial Adhesion

R. Zingali¹, B. Succar¹, V. David¹, R. Saldanha-Gama², F. Ceneviva Lacerda de Almeida¹, L. Wermelinger Serrão³, C. Barja-Fidallgo², E. Kurtenbach⁴
Abstract Number: PB1948

The Red Laser- Mediated Photobiomodulation Therapy, Accompanied by Aspirin Administration, Improve Endothelial Dysfunction after Balloon Angioplasty in the Rabbit Model of Carotid Artery Injury

H. Mehrad¹, A. Foletti²
Abstract Number: PB1245

The Relationship between Platelet Phenotype and Function with Clinical Outcomes in 57 Paediatric Veno-Arterial ECMO Patients

S. Van Den Helm¹, H.P. Yaw^1,2, N. Letunica¹, R. Barton^1,2,3, F. Newall^1,2,3, S. Horton^2,4, G. MacLaren^1,5,6, R. Chiletti^5,7, A. Johansen^5,7, D. Best^5,7, J. McKittrick⁵, W. Butt^2,5,7, Y. d'Udekem^1,2,8, M. Linden⁹, P. Monagle^1,2,3, V. Ignjatovic^1,2
Abstract Number: PB0848

The Relationship between Societal Costs Associated with Haemophilia and Disease Severity: A Regression Analysis Using CHESS II Data

T. Burke¹, A. Shaikh¹, J. O'Hara^1,2, N. Misciattelli³, S. Kar³, M. Blanco³, A. Nathwani^3,4
Abstract Number: OC 07.5

The Relative Impact of Treatment Approaches on the Outcome of Catastrophic Antiphospholipid Syndrome (CAPS): Analysis of an Updated Database

P.A. Haddad, D. Hammoud, K. Gallagher
Abstract Number: PB2345

The Review of the Data from the National Registry of Thrombophilic States in the Slovak Republic

L. Stanciakova, T. Simurda, M. Dobrotova, P. Holly, I. Plamenova, J. Ivankova, K. Kulichova, P. Kubisz, J. Stasko
Abstract Number: PB1782

The Role of Antithrombin in Complement Activation: Pilot Data from Patients with Inherited Antithrombin Deficiency

K. Mayger^1,2,3, J. Young², R. Greenlaw⁴, R.A. Smith⁴, S. Sacks⁴, B.J. Hunt²
Abstract Number: PB2526

The Role of Antithrombotic Therapy in the Prevention of Adverse Pregnancy Outcomes

A. Makatsariya, K. Sultangadzhieva, M. Arslanbekova, J. Khizroeva, V. Bitsadze, E. Egorova, N. Babaeva, T. Mashkova
Abstract Number: PB0988

The Role of Clinical Psychologist in Mothers of Children with Hemophilia

A. Nakao, J. Yamanouchi, T. Hato, K. Takenaka
Abstract Number: PB1678

The Role of Coagulation-generated Components on GPVI-mediated Platelet Activation

I. De Simone^1,2, C. Jones², J. Gibbins², H. ten Cate¹, J. Heemskerk¹, P.E.J. van der Meijden¹
Abstract Number: PB0039

The Role of ERp44 in the Atherosclerosis

Q. Lu
Abstract Number: PB0805

The Role of Genetic and Environmental Factors in Development of Inhibitor in Hemophilia A

N.B. Mirbehbahani¹, A. Rashidbaghan²
Abstract Number: PB2061

The Role of Hemodialysis in Patients with Re-Elevation of Dabigatran Levels After Idarucizumab Treatment: A Case Series

A. Boban^1,2, M. Milos³, C.H. Desiree³, T. Tomic Mahecic⁴, M. Grgic Medic⁵, Z. Renata³
Abstract Number: PB1276

The Role of Hereditary Elevated Lipoprotein (a) as a Thrombophilic Risk Factor in Two Siblings with Cerebral Vein Thrombosis

S. Schober¹, C. Deppisch¹, U. Holzer¹, R. Handgretinger¹, U. Ernemann², N. Kaiser¹, V. Icheva¹, G. Wiegand¹
Abstract Number: PB0454

The Role of Phosphatidylserine-Exposing Microparticles and Glycophorin-Exposing Microparticles in Hemostasis System in Children with Hemolytic Anemia

E. Seregina^1,2, E. Lipets^1,2, A. Poletaev¹, T. Vuimo^1,2, F. Ataullakhanov^1,2,3, N. Smetanina^1,4
Abstract Number: PB1683

The Role of Platelets in the Adhesion of Normal Freshly Isolated Lymphocytes to Fibrin

A. Solpov¹, E. Bogomyakova², O. Solpova³, Y. Vitkovsky⁴
Abstract Number: PB1225

The Role of the Nurse in the Therapeutic Education of Hemophiliac Patients in Preparation for Physiotherapy

M. Djaafri, D. Saidi, R. Messaoudi, H. Touhami
Abstract Number: PB0406

The Role of the Protein C Pathway in Hemostasis: The Importance of Physiological Context

T.T. Marar¹, L. Nettey¹, C. Matzko¹, I. Poventud-Fuentes¹, C.T. Esmon², T.R. Sinno³, L.F. Brass¹, T.J. Stalker¹, M. Tomaiuolo¹
Abstract Number: PB1554

The Role of the von Willebrand Factor Propeptide (VWFpp) in the Evaluation of Desmopressin Response in a Patient with Acquired von Willebrand Syndrome (AVWS)

P. Colpani¹, L. Baronciani¹, G. Cozzi¹, S.M. Siboni¹, E. Biguzzi¹, C. Novembrino¹, F. Rossi¹, F. Peyvandi^1,2
Abstract Number: PB0874

The Role of Ultrasonography versus MRI in the Diagnosis of Joint Problems in Hemophilic Children

O. El Safi¹, M. Besheer¹, M. Fathy¹, S. Shehata², M. Abdel Fatah¹, M. Gabal², M. Amin², A. Osama³
Abstract Number: PB1997

The Role of α1AMP-Activated Protein Kinase (α1AMPK) in Haemostatic Dysfunctions Induced by Sepsis

J. De Poortere¹, M. Angé¹, L. Bertrand¹, C. Beauloye^1,2, S. Horman¹, D. Castanares-Zapatero^1,3
Abstract Number: PB1524

The Scavenger Receptor Scara5 Mediates Clearance of the von Willebrand Factor Propeptide

O. Rawley, K. Nesbitt, C. Dwyer, L. Swystun, D. Lillicrap
Abstract Number: PB2341

The Season Role in the Occurrence of Thromboembolic Disease

W. Skouri¹, F. Said², I. Naceur², H. Baccouche³, M. Lamloum¹, I. Ben Ghorbel¹, M. Khanfir², M.H. Houman², N. Ben Romdhane³
Abstract Number: PB0513

The Sensitivity of Two New APTT Reagents to Factors VIII, IX and XI

A. Bowyer, S. Kitchen, R. Maclean
Abstract Number: PB0602

The Severity of Hemophilia A Patients Varies among Different Types of Factor VIII Gene Mutation

Y. Li¹, W. Jin¹, Q. Li², L. Li¹
Abstract Number: PB2184

The Sex-Related Risk of Venous Thromboembolism Attributed to Recognized Prothrombotic Genotypes

C.A.L. Arnesen¹, L.H. Evensen¹, K. Hveem^2,3, M.E. Gabrielsen^2,3, B.M. Brumpton^2,4, J.-B. Hansen^1,5, S.K. Brækkan^1,5
Abstract Number: PB2293

The Significance of Haemostatic System’s Changes in the Assessing of Unfavorable Prognosis in Patients with Burn Injury

E. Klychnikova, V. Borisov, E. Tazina, A. Bogdanova, M. Kaplunova
Abstract Number: PB1354

The Significance of Platelet Factor 4 (Pf4 Antibody) in Diabetic and Non-Diabetic Population during Heparin Therapy In Pakistan

R.A. Abbasi¹, I.D. Ujjan¹, A. Naz², K. Amir¹, N. Hafeez¹
Abstract Number: PB0618

The SSC Working Party on Thrombin Generation: Inventory of Thrombin Generation Methods

M. Ninivaggi¹, R. de Laat-Kremers¹, K. Devreese^2,3, B. de Laat¹
Abstract Number: PB0049

The State of Carotids and the von Willebrand Factor Levels in Patients with Arterial Hypertension

E. Shorikov¹, D. Shorikova¹, P. Shorikov², O. Khukhlina¹
Abstract Number: PB1529

The Super Glue of Ultra-Large Multimers – Characterisation of Recombinant and Platelet Derived von Willebrand Factor

T. Kragh¹, M. Spannagl¹, H.W. Ott², P. Möhnle^1,3, I. Pekrul^1,3
Abstract Number: PB1975

The survival of endothelial cells in the conditions of nutrient deficiency

T. Nikolaienko, L. Garmanchuk, V. Nikulina
Abstract Number: PB0852

The Synergistic Effect of Emicizumab and Factor VIIa on Thrombin Generation Is Dependent on Factor VIIa Activation of Factor IX

D. Monroe¹, M. Ezban², M. Hoffman^3,4
Abstract Number: PB1289

The Throm-PED Registry: The Cornerstone of the International Pediatric Thrombosis Network

C.H. van Ommen¹, M. Albisetti², M. Bhatt³, M. Bonduel⁴, M. Bordbar⁵, B. Branchford⁶, E. Chalmers⁷, A. Chan³, S. Holzhauer⁸, J. Jaffray⁹, C. Male¹⁰, P. Monagle¹¹, U. Nowak-Göttl¹², L. Raffini¹³, S. Revel-Vilk¹⁴, N. Sirachainan¹⁵, IPTN Consortium
Abstract Number: PB1987

The Tissue Factor Expression of Monocyte Subsets and the Activation of Coagulation during Human Endotoxaemia

K. Musgrave^1,2, J. Scott¹, W. Sendama^1,3, H.M.H. Spronk⁴, R. van Oerle⁴, H. ten Cate⁴, P. Kesteven², M.-H. Ruchaud-Sparagano¹, A. Rostron^1,5, A.J. Simpson^1,3
Abstract Number: PB1986

The Tissue Factor Surface Expression of Monocyte Subsets during Sepsis

K.M. Musgrave^1,2, J. Scott¹, W. Sendama^1,3, P. Kesteven², M.-H. Ruchaud-Sparagano¹, A. Rostron^1,4, A.J. Simpson^1,3
Abstract Number: PB2272

The Use of ADJUST (age-adjusted) D-Dimer Cut-off in the Assessment of Individuals Over 50 Years Old with Suspected Deep Vein Thromboses Can Decrease the Need for Compression Ultrasonography: Initial Results of a Prospective Primary Care Study

A. Hughes, B. Piper, K. Jennings, K. North, B. Varghese, D. Kawira, M. Good, K. Good
Abstract Number: PB0506

The use of an Automated Thrombin Generation Assay for the Measurement of Emicizumab and Recombinant Factor VIII in Spiked Plasma

A. Bowyer, S. Kitchen, R. Wardle, R. Maclean
Abstract Number: PB2410

The Use of Fondaparinux for Recurrent Thrombotic Events

Z. Sayar, S. Burke, H. Cohen
Abstract Number: PB0108

The Use of in Vitro Clot Lysis Assay for Predicting Outcomes in Non-traumatic Intracerebral Hemorrhage Stroke Patients

R. Orbán-Kálmándi¹, T. Árokszállási², I. Fekete², K. Fekete², M. Héja², J. Tóth³, F. Sarkady¹, L. Csiba², Z. Bagoly^1,4
Abstract Number: PB0485

The Use of Platelet Transfusions during Extracorporeal Membrane Oxygenation in a Large Tertiary Centre

A. Doyle¹, B. Sanderson², F. Vasques², D. Wyncoll², N.A. Barrett², B.J. Hunt¹, L. Camporota², A. Retter²
Abstract Number: PB2482

The Use of Thrombolytic Therapy in a Multidisciplinary Pulmonary Embolism Response Team

A. Kramer^1,2, C.S. Mortensen^1,2, J.G. Schultz^1,2, N. Giordano¹, H. Zheng³, A. Andersen², J.E. Nielsen-Kudsk², C. Kabrhel¹
Abstract Number: PB1422

The Utility of a Platelet Count-Based Electronic Medical Record Alert to Facilitate Diagnosis of Heparin-Induced Thrombocytopenia

J. May¹, L. Taylor², P.W. Varden², E. Wallace³, M. Marques⁴
Abstract Number: PB1543

The Utility of ISTH-BAT in Iranian Patients with von Willebrand Disease

O. Seidi Zadeh, M. Ahmadinejad
Abstract Number: PB0772

The VWF/ADAMTS13 Unbalance, but Not Global Coagulation or Fibrinolytic Status, Is Associated with Outcome and Bleeding in Patients with Acute Liver Failure

E. Driever¹, R.T. Stravitz², J. Zhang³, J. Adelmeijer¹, V. Durkalski³, W.M. Lee⁴, T. Lisman¹
Abstract Number: PB1098

The World Federation of Hemophilia Gene Therapy Registry

B. Konkle^1,2, D. Coffin¹, M. Naccache¹, C. Cary³, L.A. George⁴, A. Iorio⁵, B. O'Mahony⁶, S.W. Pipe⁷, M.W. Skinner⁸, C. Watson⁹, F. Peyvandi^10,11, J.N. Mahlangu^12,13, G.F. Pierce¹
Abstract Number: PB1419

Therapeutic Plasma Exchange in the Pre-Operative Management of Acute HIT

C. Cavalié, N. Gendron, S. Provenchère, R. Sonneville, E. Kantor, D. Faille, N. Ajzenberg
Abstract Number: PB0710

Thermostable Inhibitor of Contact Activation (TICA) Fully Blocks Contact Activation when Added to Blood Withdrawal Tubes

T. van de Berg^1,2, D. Suylen¹, S. Thomassen¹, R. van Oerle¹, H. Spronk¹, R. Apitz³, C. Hemker¹, T. Hackeng¹
Abstract Number: PB0997

Third Time´s the Charm? Tachyphylaxis of Desmopressin Response in Non-Severe Hemophilia A Patients and Comparison to Earlier Response: The DAVID Study

L.G.R. Romano¹, L.M. Schütte¹, R.M. van Hest², K. Meijer³, B.A.P. Laros-van Gorkom⁴, L. Nieuwenhuizen⁵, J. Eikenboom⁶, F.C.J.I. Moenen⁷, N. Uitslager⁸, M. Coppens⁹, M.H. Cnossen¹⁰, K. Fijnvandraat^11,12, M.H.E. Driessens¹³, S. Polinder¹⁴, F.W.G. Leebeek¹, R.A.A. Mahtôt², M.J.H.A. Kruip¹
Abstract Number: PB0389

Thr90Ser Mutation in Antithrombin Causes Recurrent Thrombosis in a Heterozygous Carrier

Y. Lu^1,2, B.O. Villoutreix³, Q. Ding¹, X. Wang¹, A.R. Rezaie^2,4
Abstract Number: PB2170

ThroLy and Khorana Scores Comparation in a Group of Lymphoma Patients

P. Llamas¹, A. Garcia Raso², A. Lopez², J.M. Alonso², D. Velasco², D. Morillo², C. Dbouk², R. Vidal², R. Cordoba²
Abstract Number: PB0567

Thrombin Generation Analysis in Patients with Venous Thromboembolism and Atrial Fibrillation on Anticoagulant Tehrapy: Comparison between Direct Oral Anticoagulants and Antivitamin K Antagonists

C. Dellanoce, O. Paoletti, V. Cancelli, E. Cancellieri, R. Morandini, B. Kaur, M. Tala, S. Zambelli, S. Testa
Abstract Number: PB1030

Thrombin Generation Assay to Tailored Treatment in Hemophilia a Patients

M.D.L. Herrera^1,2, S. Pons^1,2, E. Sueldo³, M. Arias³, A. Baques⁴, P. Do Nascimento⁴, A. Scazziota^1,2
Abstract Number: PB0138

Thrombin Generation Following Vipera berus Envenomation: A Canine Model

H.J. Harjen¹, M. Hellum^2,3, M. Oscarson¹, R. Rørtveit⁴, K.P. Anfinsen¹, E.R. Moldal¹, C.E. Henriksson^2,3
Abstract Number: PB0106

Thrombin Generation in Patients with Non-traumatic Intracerebral Hemorrhage

L. Lóczi¹, T. Árokszállási², I. Fekete², K. Fekete², M. Héja², F. Sarkady¹, R. Orbán-Kálmándi¹, J. Tóth³, L. Csiba², Z. Bagoly^1,4
Abstract Number: PB/CO17

Thrombin Generation in Severe COVID-19 Patients Hospitalized in the ICU

M.G. Zermatten¹, F.J. Gomez¹, O. Pantet², M. Papadimitriou-Olivgeris^3,4, O. Hugli⁵, P.-A. Bart⁶, A. Aliotta¹, D. Bertaggia Calderara¹, M. Méan⁶, L. Mazzolai⁷, L. Alberio¹, The COVID-19 Interdisciplinary Collaboration
Abstract Number: PB0903

Thrombin Generation is a Better Predictor for Factor VIII Replacement Therapy Effect Than Factor VIII Activity Levels

L.L.F.G. Valke^1,2, L.H. Bukkems³, N.M.A. Blijlevens¹, R.A.A. Mathôt³, W.L. Van Heerde^2,4, S.E.M. Schols^1,2
Abstract Number: PB1247

Thrombin Generation Measurement Using ST-Genesia System in a Cohort of Healthy Children Including Neonates: Normal Values and Variability

P. Nguyen^1,2, L. Kanagaratnam³, C. Deleage¹, C. Amory⁴, N. Bednarek⁵, C. Ballan¹, N. Hezard⁶
Abstract Number: PB1146

Thrombin Generation Potential of Modified FIX: Dalcinonacog Alfa

S. Williams, E. Gray
Abstract Number: PB0054

Thrombin-Induced Platelet Fibrin Clot Strength Identified by Thromboelastography: A Potential Marker of Increased Thrombotic Risk in Older Adults with Coronary Artery Disease

R. Chaudhary¹, S. Pagali¹, K. Bliden², U. Tantry², P. Gurbel²
Abstract Number: OC 14.5

Thrombin-PAR1/2 Signaling Axis Modulates TLR3-Mediated Procoagulant, Proinflammatory, and Proadhesive Responses in Vascular Endothelial Cells

S. Subramaniam^1,2,3
Abstract Number: PB0311

Thrombocytopenia in adult ICU patients with sepsis

L. Russell, N. Haase, A. Perner
Abstract Number: PB0482

Thromboelastometry Identifies Coagulopathy Associated with Liver Failure and DIC Caused by Yellow Fever, Guiding Specific Hemostatic Therapy: A Case Report

T. Crochemore, F. Savioli
Abstract Number: PB0086

Thromboembolism in Thalassemia Patients: Is Aspirin Protective against Brain Ischemia over Three Years Follow Up in Beta Thalassemia Patients?

M. Karimi¹, S. Haghpanah¹, P. Eshghi²
Abstract Number: PB0275

Thrombohemorragic Events and Management of Haemostasis in Adult Patients under Berlin Heart Excor Devices

M. Argüello¹, E. Zatarain², G. Pérez-Rus¹, I. Sousa², M.J. Valero², J. Velásquez², M. Martínez-Sellés², J.L. Diez-Martin¹, C. Ortiz², C. Pascual¹
Abstract Number: PB2030

Thrombomodulin Makes the Difference – Novel Role of Protease-Activated Receptor 4 as Low-Dose Thrombin Receptor

D.M. Heuberger, D. Ardizzone, R.A. Schuepbach
Abstract Number: PB0006

Thrombophilia and Myocardial Infarction with Non-Obstructive Coronary Arteries

A. Golub¹, I. Bokarev², L. Popova³, T. Khlevchuk¹, M. Kanevskaia¹, T. Kondrateva¹, M. Aksenova¹, A. Gerasimov³, L. Patrushev⁴, T. Kovalenko⁴, Y. Belenkov¹
Abstract Number: PB2241

Thrombophilia and Thrombotic Complications in Armenia

H. Khachatryan¹, L. Sahakyan², N. Sargsyan^1,3, L. Petrosyan¹, L. Hambardzumyan^2,4, I. Melnichenko^3,4, S. Petrosyan⁵, G. Tamamyan^3,4, S. Danielyan²
Abstract Number: PB2180

Thrombophilia Gene Screening in Pediatrics Solid Tumors with Thrombosis

O. El Safy¹, M. Fathy¹, A. Osama², M. Zakaria¹, S. Fehr¹, N. Raafat³
Abstract Number: PB2230

Thrombophilia Testing in Algerian Pediatric Patients

I. Hocine, Y. Ferhat-Hamida, G. Hariti
Abstract Number: PB2228

Thrombophilia Testing in Patients with Arterial Thrombosis in Routine Clinical Practice

G.A. Méndez Navarro
Abstract Number: PB2245

Thrombophilic Abnormalities Screening in Elderly Women Patients with Venous Thrombosis

L. Hurjui^1,2, L.I. Șerban¹, C. Delianu¹, I.A. Hurjui¹, R.M. Hârțan¹, C.C. Tarniceriu¹, I. Hurjui¹, I. Gradinaru¹
Abstract Number: PB2248

Thrombophilic Mutations in Macedonian Women with Adverse Pregnancy Outcome

E. Petkovikj¹, A. Hristova Dimceva¹, R. Grubovic¹, S. Useini¹, V. Petkovska¹, T. Makarovska Bojadzieva¹, E. Ristovska²
Abstract Number: PB1610

Thrombopoiesis in Bone Marrow Culture in Norm and in Some Pathological States

T. Saralidze¹, T. Svanidze¹, I. Mamatsashvili¹, N. Metskhvarishvili², M. Rizhvadze³, M. Jangidze⁴, M. Noniashvili¹
Abstract Number: PB2035

Thrombopoietin Rescues Megakaryopoiesis, Reduces Hemorrhage via Protecting Bone Marrow Endothelial Function of Chemotherapy-Treated Hematological Malignancies Patients

X. Zeng, Y. Jiao, Z. Li, Y. Zhang, J. Ye
Abstract Number: PB2386

Thromboprophylaxis Audit in a Public Hospital – The Impact of Protocol Implementation

P.H. Fernandes do Carmo Las Casas¹, J.E. Machado Veloso¹, D. Coelho Cavalcante¹, M. Fernandes Nogueira¹, A.L. Ferreira de Brita¹, M. Aredes Lima¹, A. Gorle de Miranda Chaves¹, F.C. Barbosa Lana², I. Almeida Pessoa¹
Abstract Number: PB2525

Thromboprophylaxis during Pregnancy – 10-year Review of Women Seen in the Haematology Clinic at King’s College Hospital (KCH)

N. Rajaratnam¹, J. Patel^1,2, L. Roberts², J. Czuprynska², R. Patel², R. Arya²
Abstract Number: PB2356

Thromboprophylaxis to International Conferences and Number of Thromboses (PINOT) study

H. Stevens^1,2,3, S. Campbell^2,4, N. Waters⁵, J. McFadyen^1,2,3, H. Tran^1,2
Abstract Number: PB2137

Thromboprophylaxis with Rivaroxaban in Patients with Malignancy and Central Venous Lines (TRIM-line): a Multi-centre Open-label Pilot Randomized Controlled Trial

R. Ikesaka¹, D. Siegal², D. Witham³, C. Webb⁴, M. Carrier⁵
Abstract Number: PB1290

Thrombosis and Anticoagulant Therapy among Pediatric Patients with Active Cancer: Real Life Data

H. Abdel-Razeq, M. Zeineddin, N. Amayiri, W. Alqasem, I. Sultan, B. Hammo, H. Hashem
Abstract Number: PB1935

Thrombosis and Antiphospholipid Antibodies

I. Nikoloska, R. Apostolovska, V. Neceva, S. Useini
Abstract Number: PB1291

Thrombosis and Laboratory Monitoring in Children with Acute Lymphoblastic Leukemia

E. Seregina^1,2, L. Zharikova¹, N. Trubina¹, M. Korsantiya¹, M. Gracheva¹, T. Vuimo^1,2, A. Poletaev¹, F. Ataullakhanov^1,2,3
Abstract Number: PB2106

Thrombosis in Hematologic Malignancies: A Five Year Single-Center Experience in Mexico

C. Ledesma de la Cruz¹, M.T. García-Lee¹, L.O. Guzmán-Chores¹, J.E. Castellanos-Galán¹, Y. Lugo-García¹, J. Juárez-Lara¹, A.S. Majluf-Cruz²
Abstract Number: LB/CO01.2

Thrombosis, Bleeding, and the Effect of Anticoagulation on Survival in Critically Ill Patients with COVID-19 in the United States

H. Al-Samkari^1,2, S. Gupta^2,3, R. Karp Leaf^1,2, W. Wang⁴, R. Rosovsky^1,2, K. Bauer^2,5, D. Leaf^2,3, STOP-COVID Investigators
Abstract Number: PB1622

Thrombotic Disease Caused by Hypothermia-Induced Activation of the Splenic Platelet Pool in a Mouse Model

K. Horioka¹, H. Tanaka², S. Isozaki², H. Druid¹
Abstract Number: PB1214

Thrombotic Events in the Patients with Haemorrhagic Disorders of Haemostasis

L. Stanciakova¹, M. Dobrotova¹, P. Holly¹, M. Brunclikova¹, M. Samos², T. Bolek², P. Kubisz¹, J. Stasko¹
Abstract Number: PB1912

Thrombotic Outcomes in Pregnant Women with Antiphospholipid Antibodies in a Tertiary Referral Centre

A. Rottenstreich^1,2, K. Schreiber¹, M. Frishman¹, K. Breen¹, S. Robinson¹, M.J. Cuadrado¹, M.A. Khamashta¹, B.J. Hunt¹
Abstract Number: PB0705

Thrombus Formation Study of Upstream Activation and Downstream Adhesion of Platelets in a Highly Integrated Microfluidic System

S. Xu, J. Piao, S. Shin
Abstract Number: PB1397

Ticagrelor Mechanism of Action on Gram-Positive Bacteria

L. Musumeci¹, N. Jacques¹, N. Penoy², G. Piel², E. Goffin², B. Pirotte², A.M. Amoroso³, B. Joris³, O. Verlaine³, P. Lancellotti^1,4, C. Oury¹
Abstract Number: PB2072

Time in Therapeutic Range During Therapy with Vitamin K Antagonists Is Lower in Women than in Men and Is Not Explained by Differences in Age

I. Avarello¹, M.L. Zighetti¹, V. Toschi¹, E.M. Faioni^1,2
Abstract Number: PB2447

Time in Therapeutic Range in Venous Thromboembolic Diseases in a North African Geriatric Population

M. Mrouki, S. Zrida, Y. Cherif, S. Derbel, F. Ben Dahmen, M. Abdallah
Abstract Number: PB2205

Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome (The TILE Pilot Study): Rationale and Study Protocol

J.P. Galanaud¹, J. Abdulrehman², A. Delluc³, S. Schulman⁴, S. Kahn⁵
Abstract Number: PB0055

Tissue Factor Cytoplasmic Tail Promotes Inflammatory Myeloid Cell Derived Superoxide Formation and TGF-β1 Driven Cardiac Remodeling in Myocardial Infarction

V. Garlapati^1,2, M. Molitor^1,2,3, P. Efentakis¹, J. Lagrange¹, R. Schüler^1,3, J. Wild^1,2,3, M. Knorr^1,3, S. Karbach^1,2,3, K. Vujacic-Mirski³, T. Münzel^1,2,3, A. Daiber^2,3, M. Brandt^1,2,3, S. Kossmann^1,3,4, H. Milting⁵, T. Gori^2,3, W. Ruf^1,2,6, P. Wenzel^1,2,3
Abstract Number: PB0417

Tissue Factor Pathway Inhibitor Is Increased in Plasma of Patients with a mild to Moderate Bleeding Tendency Independent of Known Genetic Variations in the factor V Encoding Gene

D. Mehic¹, A. Tolios², S. Hofer¹, H. Haslacher³, J. Rejtö¹, C. Ay¹, M. Haimel⁴, I. Pabinger¹, W. Ouwehand⁵, K. Downes⁵, J. Gebhart¹
Abstract Number: PB2329

Tissue Factor Pathway Inhibitor, Activated Protein C Resistance and Risk of Venous Thrombosis Associated with Menopausal Hormone Therapy

D. Khialani¹, S. Vasan², M. Cushman³, A. Dahm⁴, P. Morten Sandset⁴, J. Rossouw⁵, A. van Hylckama Vlieg¹
Abstract Number: PB0231

To Determine the Effect on Gender and Age of Prothrombin Time (PT), Activated Partial Thromboplastin Time (aPTT) Levels and International Normalized Ratio (INR)

A. Sultana
Abstract Number: PB0746

To Evaluate the Effect of Hydroxyurea on Blood Coagulation and Endothelial Activation in Sickle Cell Disease

M. Borhany, M. Abid, S. Zafar, T. Shamsi
Abstract Number: PB1827

Toll-Like Receptor 2 Ligands Promote and Enhance Platelet Activation

I. Parra-Izquierdo, A.R. Melrose, S. Hitesh, J. Pang, O.J.T. McCarty, J.E. Aslan
Abstract Number: PB0672

Top 50 Cited Papers in Developmental Hemostasis: A Scoping Review

P.T. Tieu^1,2, S. Afraz², H.M. Ho³, N. Thai⁴, A.K.C. Chan^2,5, D. Matino²
Abstract Number: PB0752

Total and C-terminally Truncated Alpha2-plasmin Inhibitor Levels in Venous Thrombosis

É. Katona, B. Baráth, T. Miklós, D. Pituk, V. Fedoriska, L. Muszbek, Z. Bereczky
Abstract Number: PB0884

Total Elbow Replacement: Financial Burden Impact

J. Restrepo-Avenia, J.H. Ramirez-Varela, J.E. Duque-Gil
Abstract Number: PB0931

Total Hip Arthroplasty In Avascular Necrosis of the Femoral Head in a Patient with Hemophilia A

J. Cabral, D. Brito, M. Calheiros, C. Calaza, A. Marques
Abstract Number: PB1078

Total Knee Arthroplasty in Patients with Hemophilia A and B: Impact on Quality of Life

A. Nunes Loureiro Prezotti, J. Souza Mario Duarte, S. Soraya Marcondes, M.D.P.S. Vendramini Orletti, D. Maria do Carmo Rocha, A. Rocha Neto, B. Calatrone Altoe, L. Souza Arnoni, B. Prucoli, G. Louredo, C.R. Silva Pacheco, L. Lacerda Montezi
Abstract Number: PB1361

TOutcomes of Patients with Worsening Acquired Thrombotic Thrombocytopenic Purpura (TTP) Despite Daily Therapeutic Plasma Exchange (TPE) in the Phase 3 HERCULES Trial

M. Scully¹, J. de la Rubia^2,3, F. Peyvandi^4,5, S. Cataland⁶, P. Coppo⁷, J.A. Kremer Hovinga⁸, P. Knoebl⁹, K. Pavenski¹⁰, F. Callewaert¹¹, J. Minkue Mi Edou¹², R. de Passos Sousa¹³
Abstract Number: PB1722

Towards Complete Assignment of the Full Platelet Proteome and Transcriptome

J. Huang^1,2, I. Provenzale¹, L. Grassi³, F.M. Solari², A. Sickmann², M. Frontini³, J.W.M. Heemskerk¹, F. Swieiringa¹
Abstract Number: PB2073

Towards Individualizing Apixaban Therapy in Elderly Patients Through Thrombin Generation

A. Scazziota^1,2, S. Pons^1,2, M.D.L. Herrera^1,2, S. Aguirre^1,3, V. Monserrat^1,3, M. Nuñez⁴, A. Brodsky⁵, R. Perez de la Hoz⁶
Abstract Number: PB1702

Towards the Correlation of Age with Size in Human Platelets under Steady State

M. Wolff, S. Handtke, A. Greinacher, T. Thiele
Abstract Number: PB0724

Transcriptome Profiling of Coagulation Factor XIII Genes: Implications for Pleiotropic Pathways and Inter-Subunit Regulation

M.A. Jamil¹, S. Singh¹, A.S. Wolberg², O. El-Maarri¹, J. Oldenburg¹, A. Biswas¹
Abstract Number: PB0740

Transition Patterns in the Fibrinolytic Response are Superior to Admission ROTEM Values in Stratifying Risk for Late Clinical Outcomes after Major Trauma

A. Rossetto^1,2, P. Vulliamy^1,2, K. Brohi^1,2, R. Davenport^1,2
Abstract Number: PB0193

Transplacental Delivery of Fc-fused Factor VIII (rFVIIIFc) in FVIII-Deficient Mice

S. Delignat¹, A. Azam¹, A. Mimoun¹, M. Georgescu², D. Lillicrap², S. Lacroix-Desmazes¹
Abstract Number: PB0177

Transplacental Delivery of Maternal Factor VIII for Induction of Immune Tolerance to Therapeutic Factor VIII

A. Mimoun^1,2, M. Bou Jaoudeh^1,2, I. Peyron^3,4, V. Daventure^1,2, S. Delignat^1,2, O. Christophe^3,4, P. Lenting^3,4, C. Denis^3,4, L.-D. Sébastien^1,2
Abstract Number: PB2037

Transplantation of Fetal Liver Cells into Newborn Hemophilic Mice for Hemophilia A Cell Therapy

S. Merlin¹, S. Buzzi¹, S. Akula¹, E. Borroni¹, V. Kalandadze¹, T. Garcia-Leal², L.J. Serrano³, A. Liras³, M.J. Sanchez², A. Follenzi¹
Abstract Number: PB0033

Trash Feet: Is Anticoagulation Therapy Useful?

V. Chadachan, N. Pandit
Abstract Number: PB1918

Treating Antiphospholipid Syndrome Patients with Vitamin K Inhibitors in Real Life; Long Term Outcomes from a Single Centre Retrospective Study of 101 Patients

I. Venkatadasari, G. McIlroy, M. Ahmed, M. Any, M. Kaparou, C. Kartsios
Abstract Number: PB0331

Treatment and Joint Health in Nordic Moderate Haemophilia Patients – the Mohem Study

R.J. Måseide^1,2,3, E. Berntorp⁴, J. Astermark⁵, A. Olsson⁶, M. Bruzelius^7,8, T. Frisk⁹, V. Nummi¹⁰, R. Lassila¹⁰, G.E. Tjønnfjord^1,3, P.A. Holme^1,2,3
Abstract Number: PB1892

Treatment of Acquired Thrombotic Thrombocytopenic Purpura in Rituximab Era: A Single Center Experience from India

N. Gupta¹, S. Langer², A. Saraf², J. Kotwal², A. Sharma¹
Abstract Number: OC 12.5

Treatment of Heavy Menstrual Bleeding in a Multidisciplinary Young Women’s Bleeding Clinic for Adolescents: An Institutional 2-year Experience

M.C. Brown^1,2, R.F. Sidonio Jr.^1,2
Abstract Number: PB1050

Treatment of Hemophilia A with rVIII-SingleChain in Italy: Physician and Patient Survey

A. Borchiellini¹, G. Castaman², G. Feola³, A. Ferretti⁴, P. Giordano⁵, M. Luciani⁶, G. Malcangi⁷, M. Margaglione⁸, A.C. Molinari⁹, B. Pollio¹⁰, A. Rocino¹¹, E. Santagostino¹², C. Santoro⁴, R. Santoro¹³, M. Schiavulli¹⁴, E. Zanon¹⁵
Abstract Number: PB0888

Treatment of Hemophilic Arthropathy with Hyaluron

A. Makhmudova, I. Berger, L. Ashurova, N. Akhrarova, O. Madasheva
Abstract Number: PB1339

Treatment of Immune Thrombocytopenia with Eltombopag in Children: Single Center Experience

A. Ayhan
Abstract Number: PB1120

Treatment Options in Severe Hemophilia A Patients from Romania: What Role did the Intron 22 Inversion and Age Play?

M.-A. Gaman^1,2, M. Brinza³, V. Uscatescu³, A. Diaconu³, A. Grigore⁴, M. Dragomir³, D. Coriu¹
Abstract Number: PB1020

Treatment Patterns and Bleeding Outcomes in Persons with Severe Hemophilia A and B in a Real-World Setting

L. Perschy¹, J. Rejtö¹, I. Pabinger¹, C. Ay¹, A. Kaider²
Abstract Number: PB1556

Treatment with Emicizumab Leads to Clinical Improvement in a Type 3 von Willebrand Disease Patient with Inhibitor Suffering from a Left Ankle Arthropathy

M. Sigaud¹, M. Fouassier¹, C. Ternisien¹, M. Pennetier², M. Trossaert¹, N. Drillaud¹
Abstract Number: PB0955

Treatment-Based Risk Assessment of Developing Pain, Anxiety, and Depression as Compared to Matched Controls in People with Haemophilia. A Nordic Registry Study Over a Period of 11 Years

K. Steen Carlsson^1,2, B. Winding³, J. Astermark⁴, F. Baghaei⁵, E. Brodin⁵, E. Funding⁶, M. Holmström⁷, K. Österholm⁸, S. Bergenstråle³, E. Andersson¹, S. Lethagen^3,9
Abstract Number: PB1613

TREM-like Transcript-1 Is a Positive Regulator of Platelet Production and Thrombosis

C.W. Smith¹, V.A. Washington², Y.A. Senis³, A. Mazharian³
Abstract Number: PB2497

Trends in Combined Oral Contraceptive Use in the Netherlands: 2002-2016

D. Khialani, F. Rosendaal, A. van Hylckama Vlieg
Abstract Number: PB2090

Trends in Direct Oral Anticoagulant Use in Renal Failure

S. Kaatz¹, B. Haymart², X. Kong², M. Ali³, E. Kline-Rogers², J. Kozlowski⁴, G. Krol¹, V. Shah¹, G.D. Barnes², J.B. Froehlich²
Abstract Number: PB1974

Trimethylamine N-oxide (TMAO) Disrupts Haemostasis Balance in Human Vascular Endothelial Cells

S. Subramaniam^1,2, S. Boukhlouf³, C. Fletcher¹
Abstract Number: PB1955

Tripeptides Affected Hemostas in Various Pathologies

M. Golubeva, B. Umarova
Abstract Number: PB1927

Triple Positive Antiphospholipid Antibodies: A 10-year Retrospective Review of 37 Patients with Triple Positive Antiphospholipid Antibodies and their Thrombotic Outcomes and Mortality in a Single Centre in Singapore

B.E. Fan^1,2, C.L.L. Sum³
Abstract Number: PB1976

TRPV4 Channel Activation Induces the Transition of Venous and Arterial Endothelial Cells Toward a Pro-Inflammatory Phenotype

K. Beddek¹, F. Raffin², D. Borgel¹, F. Saller¹, D. Riccobono³, F.-X. Boittin³, R. Bobe¹
Abstract Number: PB1799

Tumor Platelet Transcriptome Changes in Hyperthrombotic Mice

C. Santos¹, J. Braun¹, S. Schubert¹, F. Marini^1,2, B. Schrörs³, L. Bresadola³, P. Do Dinh³, R. Wolfram^1,4
Abstract Number: PB0693

Two Cases in which Measuring Dabigatran Plasma Levels Is Indicated and Recommended

D.I. Iosub¹, F. Piovella²
Abstract Number: PB2387

Two Weeks of Low Molecular Weight Heparin for Isolated Symptomatic Distal Vein Thrombosis (TWISTER Study): Final Analysis of 242 Patients

E. Merriman¹, S. Chunilal², S. McRae³, T. Brighton⁴, P. Ockelford⁵, H. Tran⁶, J. Curnow⁷, V. Chen⁸, B. Chong⁹, M. Smith¹⁰, G. Royle¹¹, H. Crowther¹², A. Slocombe¹³, A. Cummins¹⁴, H. Tran^15,16
Abstract Number: PB0837

Two-year Update on the WFH World Bleeding Disorders Registry

M. Naccache¹, D. Coffin¹, W. Youttananukorn¹, E. Tootoonchian¹, V. Byams², S. Diop³, C. Hermans⁴, D. Noone⁵, J. O'Hara⁶, G.F. Pierce¹, A. Iorio⁷, B. Konkle⁸, E. Ayoub¹
Abstract Number: PB1534

Type 2B Mutations Differentially Alter Conformational Dynamics of VWF A1 Domain

E.R. Legan, N.A. Arce, Y. Wang, P. Lollar, R. Li
Abstract Number: PB1585

Type 2N von Willebrand Disease (VWD2N): Is it Always a Recessive Trait?

A.I. Woods¹, L. Rossetti², J. Paiva³, M.L. Romero³, A.N. Blanco³, M.M. Casinelli³, C. De Brasi^2,4, A. Sanchez-Luceros^1,3
Abstract Number: PB1686

Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-induced Coagulation: Additive Effects of Aspirin

B.M.E. Tullemans¹, D.I. Fernández¹, A. Veninga¹, M.J.B. Aarts², P.E.J. van der Meijden¹, J.W.M. Heemskerk¹, M.J.E. Kuijpers¹
Abstract Number: PB1458

Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Organization and Inhibit Platelet Function

T. Zheng, E. Lofurno, A. Melrose, J. Pang, J. Shatzel, O. McCarty, J. Aslan