ISTH 2021 Congress Archives - ISTH Congress Abstracts

Abstract Number: PO126

D Dimer and other Biomarkers in Dengue Patients within a Doble Viral Circulation Scenery (Dengue/COVID-19)

F. Chuliber¹, R. vanden Ryn², N. Schutz^1,3, L. Barrera^2,3, M.S. López^2,3, C. Raff², V. Privitera¹, D. Mezzarobba¹, M. Villagra Iturre¹, V. Estela S^1,3, D. Penchasky^1,3, G. Jimenez^2,3, M. Rolan², D. Arrigo^2,3, J. Arbelbide^1,3, F. Seoane², M. Martinuzzo^2,3
Abstract Number: PB0045

D-dimer and the Risk of Diabetes: The REasons for Geographic and Racial Differences in Stroke (REGARDS)

D. Kamin Mukaz¹, D.L. Long², T.B. Plante¹, S.E. Judd², L.A. McClure³, A.S. Wolberg⁴, A.P. Carson², B. Guo², M. Cushman¹
Abstract Number: PB0221

D-dimer as a Predictive Marker for Mortality in Hospitalized COVID-19 Patients

S. Hassan^1,2, B. Ferrari³, R. Rossio⁴, V. la Mura⁵, A. Artoni⁵, F. R. Rosendaal², R. Gualtierotti^1,3, I. Martinelli³, F. Peyvandi^1,3, COVID-19 hospital network
Abstract Number: LPB0058

D-dimer Elevation at Time of Admission Is Associated with Need for Ventilator Support among Pediatric Patients with COVID-19 Infection

N. Wilken¹, V. Kostousov^1,2, K. Bruzdoski², S. Sartain³, K. Krum^1,2, L. Hensch^1,2, J. Teruya^1,2, S.-K.R. Hui^1,2
Abstract Number: PB0258

D-dimer Increase during Hospitalization is Associated with Negative Outcomes in Patients with COVID-19 Infection

E. Panchenko¹, E. Kropacheva¹, A. Komarov¹, A. Suvorov¹, F. Paveev¹, N. Pogosova¹, S. Boytson¹
Abstract Number: PB1235

D-Dimer Test and Postoperative Thromboprophylaxis

T. Makarovska Bojadjieva¹, E. Velkova¹, V. Dejanova Ilijevska¹, E. Petkovic¹, E. Ristovska¹, S. Useini¹, R. Grubovic¹, M. Tashkovska², B. Todorovski³
Abstract Number: PB1183

D-dimer to Rule out Venous Thromboembolism during Pregnancy: A Systematic Review and Meta-analysis

M. Bellesini^1,2, H. Robert-Ebadi¹, C. Combescure³, C. Dedionigi², G. Le Gal⁴, M. Righini¹
Abstract Number: PB1036

Dasatinib Impairs Vascular Integrity and Promotes Skin Wound Healing in Mice

S. Wichaiyo¹, S. Svasti², N. Morales³
Abstract Number: PB1243

DASH Score for Prediction of Recurrent Venous Thromboembolism: Updated Long-term Outcomes from a Single-centre

A. Banerjee¹, M. Berks¹, M. Hu¹, R. Umeria¹, Y. Zhou¹, W. Thomas².
Abstract Number: PB0306

Ddimer and the Correlation with the Mortality Rate in Covid Patients: A Single Centre Report in Medan Indonesia

S.S. Widjaja¹, L. Mutiara², S. Tan², F. Fenny²
Abstract Number: PB1305

Deconstructing the Obstetric Antiphopholipid Syndrome (APS)

B. Grand¹, L.S. Voto¹
Abstract Number: OC 52.4

Deconstructing the Role of Vessel Wall Architecture on Hemostasis in a Microfluidic Model of Microvascular Bleeding

M. Sorrells¹, K. Neeves¹
Abstract Number: PB0673

Decreased Annual Bleeding Rate in Paediatric Patients with Hemophilia a and Inhibitors Treated with Emicizumab vs Bypassing Agents Experience at the National Institute of Pediatrics, Mexico City, Mexico

M. Nunez Toscano¹, N. Lopez-Santiago¹, M.d.L. Gonzalez Pedroza¹, R. Paredes Aguilera¹, G. Tavera Rodriguez¹, A. Monsivais Orozco¹, K. Maldonado Silva¹, A. Bravo Lindoro¹
Abstract Number: LPB0066

Decreased Clot Burden is Associated with Factor XIII Val34Leu Polymorphism and Better Functional Outcomes in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis

I. Szegedi¹, R. Orbán-Kálmándi², A. Nagy³, F. Sarkady², N. Vasas⁴, M. Sik⁴, L. Lánczi⁴, E. Berényi⁴, L. Oláh¹, L. Csiba⁵, Z. Bagoly⁶
Abstract Number: PB0401

Decreased Hepatic Fibrin(ogen) Deposition in a Mouse Model of Failed Liver Regeneration Is Not Associated with Systemic Coagulation Changes

D. Groeneveld¹, L.G. Poole¹, H. Cline-Fedewa¹, K.S. Baker¹, J.P. Luyendyk¹
Abstract Number: OC 56.1

Deep Molecular Mechanisms of F8 exon 19 Variants and Translational Approaches in Hemophilia A

S. Lombardi¹, L. Peretto¹, S. Merlin², A. Follenzi², J.H. McVey³, I. Maestri¹, F. Bernardi¹, M. Pinotti¹, D. Balestra¹
Abstract Number: OC 43.1

Deep Mutational Scan of the VWF C Domains to Define Mutations Associated with VWD

T. Sparring¹, K. Singh¹, H. Madarati¹, C. Kretz¹
Abstract Number: PB1167

Deep Vein Thrombosis in Young Woman Reveals a Novel Mutation on SERPINC1 Gene

F. Bargado¹, F. Rincón¹, A. Ribeiro¹, A. Mascarenhas¹, M.C. Romeiras¹, T. Araújo¹
Abstract Number: LPB0127

Defective Platelet Endocytosis of Albumin in RUNX1 Haplodeficiency Associated with Altered Caveolin-dependent Albumin Trafficking in Megakaryocytic Cells

F. Del Carpio-Cano¹, G. Mao¹, MA. Alam¹, J. Wurtzel², L. Goldfinger², A.K. Rao¹
Abstract Number: PB1016

Defining the Molecular Features of Inverse Agonism: Insights from the P2Y12 Receptor and the Antiplatelet Drug Ticagrelor

S. Bancroft¹, J. Khalil¹, S. Mundell¹
Abstract Number: OC 02.3

Defining Two Separate, but Functional, α-granule Pools in in-vitro-grown Megakaryocytes (MKs): Lessons from Urokinase Plasminogen Activator (uPA)

S. Zaitsev¹, H. Ahn¹, M.A. Kowalska¹, K. Bdeir², D.L. French¹, R. Camire³, D. Cines², M. Poncz¹, V. Stepanova²
Abstract Number: PB0850

Delayed Diagnosis of Congenital Thrombotic Thrombocytopenic Purpura Presenting as Recurrent Cryptogenic Strokes

M. Desancho¹, M. Beltrami Moreira¹
Abstract Number: PO172

Delays of VTE Prophylaxis

K. Patel¹, H. Lombardo¹, R. Fulton¹, J. Knapp¹, T. Knox¹, M. Lóser¹, A. Hallam², A. Macchiavelli^1,2
Abstract Number: OC 58.2

Delineating the Role of Low Molecular Weight Heparin in Breast Cancer Metastasis

S.P.S. Dhami¹, S. Patmore¹, J. Castle², C.C. Kirwan^2,3, J.S. O'Donnell¹, J.M. O'Sullivan¹
Abstract Number: PB0106

Delivery of a Resuscitation Fluid Cocktail Containing Fibrinogen and Vasopressin as an Infusion Rather than Boluses Improves Hemorrhage in Swine Polytrauma Model

A. St. John¹, X. Wang¹, K. Ringgold¹, S. Stern¹, N. White¹
Abstract Number: PB0598

Demographic and Clinical Characteristics of Patients with Hemophilia A in Brazil: Real-world Data from the 6th Interim Analysis of the AHEAD International Study

M.H. Cerqueira¹, C. Ferreira², C. Lorenzato³, L.E.M. Carvalho⁴, L.C Oliveira de Oliveira⁵, I. Pinto⁶, A. Prezotti⁷, J. Norton⁸, L. Tang⁹, M.C Ozelo¹⁰
Abstract Number: OC 61.2

Dense Granules Are Released Cooperatively in Activated Platelets

T.O. Shepeliuk^1,2, A.A. Masaltseva^3,4, D.Y. Nechipurenko^2,3,4, F.I. Ataullakhanov^1,2,3,4, E.L. Grishchuk¹
Abstract Number: PO155

Dentoalveolar Procedures in Immune Thrombocytopenia; Systematic Review and Practical Recommendations

W.E.M. van Dijk¹, R.J.J. van Es¹, M.E.P. Correa², R.E.G. Schutgens¹, K.P.M. van Galen¹
Abstract Number: PB0773

Depression and Anxiety Screening in a Pediatric Coagulation Disorder Program: A Brief Description of a 7-week Pilot

C. Braunreiter¹, E. Marietta¹, S. Pentoney¹, L. Vanderwal¹, B. Kurt¹, J. Bowden¹
Abstract Number: LPB0035

Desialylation Primes Platelets for Apoptosis: A New Role for ß1 Integrin

R. Grozovsky¹, H. Roweth², C. Fraser³, K. Sarosiek³, E. Battinelli²
Abstract Number: PB0837

Design of a Phase 3, Randomized, Controlled Study of Prophylactic and On-demand Treatment with Recombinant ADAMTS13 for Patients with Severe Congenital Thrombotic Thrombocytopenic Purpura

N. Jain¹, C. Marquez¹, L. Martell¹
Abstract Number: PB0992

Desipramine Reduces the Exposure of Phosphatidylserine on the Surface of Human Platelets, but Does Not Inhibit Platelet TF-induced Procoagulant Activity

O. Panes¹, M.F. Becerra¹, D. Mezzano¹
Abstract Number: PB0852

Desmopressin for Reversal of Antiplatelet Drugs in Stroke due to Haemorrhage (DASH): Second Interim Report on Recruitment from a Phase II Double Blind Randomised Controlled Trial

M. Desborough^1,2,3, R. Al-Shahi Salman⁴, S. Stanworth^1,2,5, D. Havard⁶, P.M Brennan⁴, R. Dineen⁶, T. Coats⁷, T. Hepburn⁸, L. Woodhouse⁶, P. Bath⁶, N. Sprigg⁶
Abstract Number: OC 07.4

Detection of Joint Effusions in Pediatric Patients with Hemophilia Using Artificial Intelligence-assisted Ultrasound Scanning; Early Insights from the Development of a Self-management Tool

P. Tyrrell¹, V. Blanchette², M. Mendez³, D. Paniukov³, B. Brand⁴, M. Zak⁵, J. Roth⁶
Abstract Number: PB1175

Detection of Right Ventricular Dysfunction in Acute Pulmonary Embolism by CT Scan: A Systematic Review and Meta-analysis

N. Chornenki¹, K. Poorzargar², M. Shanjer², L. Mbuagbaw², M. Crowther², A. Delluc^3,3, D. Siegal³
Abstract Number: PB0129

Determination of DNA and Histone 3 Plasma Levels for Evaluation of Leukocyte Activation in Plasma of Patients with Peritoneal Carcinomatosis

S. Mirshahi^1,2, J. Soria², I. Aldybiat², M. Pocard², M. Mirshahi²
Abstract Number: PB0908

Developing a Model for Studying von Willebrand Disease with hiPSC-derived Endothelial Cells

S. de Boer¹, R. Dirven¹, B. Laan¹, J. Eikenboom¹
Abstract Number: PB0513

Developing Predictive Models of rFVIII-Fc Half Life for Personalized Prophylaxis in Patients with Hemophilia A

C.-Y. Chang^1,2, S.-W. Lai³, Y.-L. Liu^1,2, J.-R. Tsai⁴, C.-H. Tsai⁵, C.-N. Cheng⁶, S.-H. Hu⁷, J.-T. Ku⁸, Y.-C. Chen^9,7
Abstract Number: LPB0096

Development of a 3D Tissue-engineered Neointimal Model as an Alternative to Animal Models of Human Atherosclerosis

J. Echrish^1,2, Y. Yang³, A. Harper^1,3
Abstract Number: PB0098

Development of a Cell-based Assay to Test Factor VIII Internalization Mediated by the Low-density Lipoprotein Receptor (LDLR) and LDLR-related Protein 1 (LRP1)

H. Chun¹, A.G Sarafanov¹
Abstract Number: PB0432

Development of a Computable Phenotype for Hospital-associated Bleeding: The Medical Inpatients Thrombosis and Hemostasis (MITH) Study

M. Gergi¹, K. Wilkinson¹, I. Koh¹, J. Munger¹, H. Al-Samkari², N. Smith³, N.S. Roetker⁴, M. Cushman¹, C. Holmes¹, N. Zakai¹
Abstract Number: PB1200

Development of a Computable Phenotype for Venous Thrombosis Present on Admission: The Medical Inpatient Thrombosis and Hemostasis (MITH) Study

R. Thomas¹, I. Koh¹, K. Wilkinson¹, A. Li², N. Roetker³, N. Smith⁴, A. Repp¹, C. Holmes¹, T. Plante¹, M. Cushman¹, N. Zakai¹
Abstract Number: PB1241

Development of a Modified Thrombin Generation Assay with Improved Sensitivity to Factor XIa Inhibition by the Novel Small Molecule Milvexian (BMS-986177/JNJ-70033093)

M. Bunce¹, F. Bonilla¹, J. Cardenas², J. Kotha², L. Jennings², M. Chintala¹
Abstract Number: PB1134

Development of a Multi-language Mobile App to Implement the 2019 ITAC Clinical Practice Guidelines for the Treatment and Prophylaxis of Venous Thromboembolism in Cancer Patients

D. Farge^1,2,3, C. Frere^1,4, J.M. Connors^5,6, C. Ay⁷, A.A. Khorana⁸, A. Munoz^9,10, B. Brenner¹¹, A. Kakkar^12,13, H. Rafii¹, S. Solymoss (in memoriam)³, D. Brilhante¹⁴, M. Monreal^15,16, H. Bounameaux¹⁷, I. Pabinger⁷, J. Douketis¹⁸
Abstract Number: PB1151

Development of a New Disease-specific Health-related Quality of Life Questionnaire after Deep Vein Thrombosis: Qualitative Phase of a Mixed Method Development

E. Asady^1,2, W. Ghanima^2,1,3, L.-P. Jelsness-Jorgensen^2,4, F. Klok⁵, G.J. Boon⁵, H. Skuterud Wik³
Abstract Number: PB0345

Development of a New ELISA Method for Anti-FVIIa Antibody Measurement

C. Valsecchi¹, L. Schiavone¹, H. Behrouz², Z. Ahsani², A. Saadatirad², F. Peyvandi³
Abstract Number: PB0878

Development of a Novel “Arterial Thrombosis-on-a-chip” Microfluidic Device

J. Berry¹, F.J. Peaudecerf², N.A. Masters³, K.B. Neeves³, R.E. Goldstein⁴, M.T. Harper¹
Abstract Number: PB0591

Development of a Scale in the Diagnosis and Monitoring of Arthropathy in Patients with Hemophilia Using Ultrasound (US) and MRI: Initial Report

M. Walentowska-Janowicz¹, J.B. Ćwikła^2,3, M. Brzewski¹, M. Matysiak⁴, P. Łaguna⁴
Abstract Number: PB0397

Development of an Anti-thrombotic and Anti-inflammatory Coating for Medical Devices

K. Gonzalez^1,2, K. Yu^1,2, V. Lei¹, E.M. Conway^1,2, J.N. Kizhakkedathu^1,2,3
Abstract Number: OC 50.1

Development of an Artificial Intelligence Model to Predict Venous Thromboembolic Disease in COVID-19 Patients at Hospital Admission

M.S. Marcolino¹, W.C. Silveira¹, B.B.M. Paiva¹, C. Valiense¹, M.A. Gonçalves¹, S.M. Rezende¹, M.A.P. Martins¹, M.C. Pires¹, R.T. Silva¹, L.E.F. Ramos¹, T.L.S. Sales², M.V.R.S. Silva¹, F. Anschau³, F.A. Botoni⁴, G.P. Crestani⁵, K.P.M.P. Martins¹, R.L.R. Carvalho¹, L.M. Oliveira¹, C.A. Polanczyk⁶
Abstract Number: OC 66.4

Development of an Easy-to-Use ADAMTS13 Conformation Assay Using Fiber Optic Surface Plasmon Resonance Technology

C. Dekimpe¹, Q. Bonnez¹, E. Roose¹, E. Tellier², G. Kaplanski², H.B. Feys^3,4, C. Tersteeg¹, S.F. De Meyer¹, K. Vanhoorelbeke¹
Abstract Number: PO109

Development of an Experimental Animal Carotid Artery Model of Thick-cap Fibroatheromatic Plaque with Severe Stenosis (>80%) Using High Power Blue Laser-mediated Thermal Injury and High-cholesterol Diet Injury

H. Mehrad^1,2, A. Sultan- Qurraie³
Abstract Number: PB0774

Development of Decision-making Process to Support Equitable Participant Selection in Pediatric Hemophilia Trials

K. Hamilton¹, K. Strike¹, K. Decker¹, R. Goldsmith¹, T. Almonte¹, W. Xie¹, M.D Bhatt¹, A.K. Chan¹
Abstract Number: OC 14.3

Development of Monoclonal Antibodies that Protect FV/FVa from APC-mediated Inactivation for the Treatment of Bleeding

S. Quinn¹, F. Ayombil¹, R.M. Camire²
Abstract Number: OC 63.2

Development of Neuro-Fuzzy Networks for Venous Thromboembolism Recurrence Prediction

G.Y. Ottaiano¹, J.M. Annichino-Bizzacchi², R.M. Filho³, T.D. Martins¹
Abstract Number: PB0655

Development of Ordinary Differential Equation-based aPTT and Thrombin Generation Models for Characterizing FIX-Padua Gain of Function

T. Orfeo¹, M. Gissel¹, S.J. Everse¹, E. Shehu², R. Corbau², J.H. Foley²
Abstract Number: PB1188

Diagnosing Deep Venous Thrombosis using Artificial Neural Networks and Metabolomics by ¹H-NMR Data

T.D. Martins¹, M. Quintero^2,3, L. Tasic³, T.B.B.C. Costa³, D. Stanisic³, S.A.L. Montalvão², S.C. Huber², E.V. de Paula², R.M. Filho⁴, J.M. Annichino-Bizzacchi²
Abstract Number: PB0855

Diagnosing Heparin-induced Thrombocytopenia Using Machine Learning Algorithms: First Data of the TORADI-HIT Study

H. Nilius¹, J.-D. Studt², D.A. Tsakiris³, A. Greinacher⁴, A. Mendez⁵, A. Schmidt⁶, W.A. Wuillemin⁷, B. Gerber⁸, P. Vishnu⁹, L. Graf¹⁰, T. Bakchoul¹¹, M. Nagler¹
Abstract Number: OC 21.1

Diagnosing Inherited Platelet Disorders: Immunofluorescence on the Blood Smear in Comparison with Genetic Testing

C. Zaninetti^1,2, J. Rivera³, E. Leinøe⁴, E. Zetterberg⁵, J.M. Bastida⁶, M. Rossing⁷, M. Wolff¹, C. Freyer¹, A. Greinacher¹
Abstract Number: OC 63.4

Diagnosis of Acute Pulmonary Embolism across Different Healthcare Settings: A Systematic Review and Individual Patient Data Meta-analysis

G.-J. Geersing¹, T. Takada¹, F.A. Klok², H.R. Büller³, D.M. Courtney⁴, Y. Freund⁵, G. Le Gal⁶, W. Ghanima⁷, J.A. Kline⁸, M.V. Huisman², K.G. Moons¹, S. Parpia⁹, M. Righini¹⁰, P.-M. Roy¹¹, M. van Smeden¹, M.A. Stals², P.S. Wells⁶, K. de Wit⁹, N. Kraaijpoel³, N. van Es³
Abstract Number: PB0337

Diagnosis of Disseminated Intravascular Coagulation in the Context of Human Immunodeficiency Viral (HIV) Infections in a South African Tertiary Care Setting

E. Mayne¹, A. Mayne¹, S. Louw¹
Abstract Number: PB0937

Diagnosis of von Willebrand Disease-intricacies and Challenges: An Experience from a Tertiary Care Centre in Southern India

R. Kar¹, K. Balakrishnan¹, A. Logaiyappan¹, J. Jayachandan¹, D. Basu¹
Abstract Number: PB1184

Diagnostic Accuracy of D-dimer for Splanchnic Vein Thrombosis: A Systematic Review and Meta-analysis

L.M. Attard¹, K. Vella¹, N. Riva¹, J. Calleja Agius¹, A. Gatt¹, A. Squizzato²
Abstract Number: LPB0057

Diagnostic Management of Suspected Pulmonary Embolism in Patients with COVID-19: A Prospective Cohort Study

M.A.M. Stals¹, F.HJ Kaptein¹, RHH Bemelmans², T van Bemmel³, DCW Braeken⁴, DD Deenstra⁵, YPA van Dooren⁶, LM Faber⁷, MJJH Grootenboers⁸, LR de Haan⁹, C Haazer¹⁰, A Iglesias del Sol¹¹, S Kelliher¹², RI Meijer¹³, PE Westerweel¹⁴, FA Klok¹, MV Huisman¹, on behalf of the Dutch COVID & Thrombosis Coalition (DCTC)
Abstract Number: PB1295

Diagnostic Significance of Definitions Soluble Fibrin Monomer Complexes In Patients with Preeclampsia

B. Kurbanov¹
Abstract Number: LPB0028

Difference is Risk Factors and Clinical Outcomes in Pediatric Patients with Deep Venous Thrombosis as Compared to Pulmonary Embolism

S. Suryaprakash¹, C. Sabo², A. Farooqi³, M. Rajpurkar^2,3,4
Abstract Number: PB1239

Differences in the Clot Based and Amidolytic Anti-Xa Assays for the Neutralization Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban

F. Siddiqui¹, A. Tafur², D. Hoppensteadt¹, E. Bontekoe¹, W. Jeske¹, B. Lewis¹, O. Iqbal¹, J. Fareed¹
Abstract Number: PB0117

Differences in Thrombin and Plasmin Generation Potential between East African and Western European Adults: The Role of Genetic and Non-genetic Factors

G.S. Temba¹, N. Vadaq¹, J. Wan², V. Kullaya¹, D. Huskens², T. Pecht³, M. Jaeger¹, C.K. Boahen¹, V. Matzaraki¹, W. Broeders¹, L. Joosten¹, P.G. de Groot¹, J. Schultze³, A.J. van der Ven¹, V. Kumar¹, B.T. Mmbaga⁴, B. de Laat², M.G. Netea¹, M. Roest², Q. de Mast¹
Abstract Number: PB0477

Differences in Thrombin Generating Capacity in Severe Haemophilia A

C. Hamid^1,2, J. Dunster³, E. Aradom¹, J. McVey⁴, P. Chowdary^1,2
Abstract Number: PB1211

Differences of Profile and Management of Cancer-associated Thrombosis in a RIETE’s Hospital in Brazil

J. de Abreu Couto Vieira¹, R. Santos de Oliveira Júnior¹, A.T. Cavalcanti Rocha¹
Abstract Number: PB0191

Differences of Venous Thromboembolism (VTE) Events in COVID-19 and Non-COVID-19 Hospitalized Patients

M.C. Chindamo^1,2, M.B. Manhaes², L.D. Carvalho², G.G. Sardinha², A.M. Marques², H.C. Goudar², A.B. Nunes², P.R. Carmo Jr^1,2, D.R. Salgado^1,2
Abstract Number: OC 30.4

Different Profiles of Plasma microRNAs in Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism Related to Occult Cancer

J. Oto¹, O. Tura-Ceide^2,3, V. Sánchez-López⁴, C. Font², J. Osorio^2,3, C. Bonjoch², D. Hervás⁵, E. Arellano³, P. Medina¹, I. Blanco^2,3, V. Peinado^2,3, J.A. Barberà^2,3, R. Otero^3,4
Abstract Number: PB1110

Differential Associations of Aromatase Inhibitors and Tamoxifen with Thrombin Generation and Sensitivity to Thrombomodulin: A Prospective Cohort Study

M. Blondon¹, L. Thouvenin¹, T. Lecompte¹, M. Righini¹, P. Fontana¹, A. Bodmer¹, A. Casini¹
Abstract Number: PB0667

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban by Andexanet Alfa as measured by Whole Blood Thromboelastographic Analysis

S. Mehrotra¹, D. Hoppensteadt¹, W. Jeske¹, O. Iqbal¹, A. Tafur², B. Lewis¹, J. Fareed¹
Abstract Number: PB0910

Differential Release of VWF and VWF-propeptide from Platelet Alpha-granules

M. Swinkels¹, J. Slotman², A. Houtsmuller², F. Leebeek¹, J. Voorberg^3,4, G. Jansen¹, R. Bierings¹
Abstract Number: NUR 01.7

Direct Oral Anticoagulants after Bariatric Surgery: A Quality Improvement Project

J. Bayadinova¹, L. Sardo^1,2, S. Mithoowani^1,2
Abstract Number: PB1111

Direct Oral Anticoagulants vs. Low-molecular-Weight Heparin for the Treatment of Acute Venous Thromboembolism Associated with Gastrointestinal Cancer: A Systematic Review and Meta-analysis

T. Rungjirajittranon¹, W. Owattanapanich¹, Y. Chinthammitr¹, T. Ruchutrakool¹, B. Suwanawiboon¹
Abstract Number: PB1264

Direct Oral Factor-Xa-inhibitors for the Treatment of VTE in the Obese: Do Body Weight and Body Composition Matter? A Prospective Pilot Study

K. Guetl¹, D.R. Leitner², A. Beck², J. Rabensteiner³, T. Gary¹, R.B. Raggam¹, H. Toplak²
Abstract Number: OC 60.4

Discovery and in vitro Characterization of an Antibody Fragment (Fab) which Neutralizes Milvexian (BMS-986177/JNJ-70033093)

Y. Wu¹, L. Schneeweis¹, J. Pinckney², C. Terragni², S. Mai¹, Y. An¹, J. Gordon², A. Kozhich¹, A.K. Dilger¹, W.R. Ewing¹, P. Nandi¹, J.M. Luettgen¹
Abstract Number: PB1023

Discovery of WNT/Planar Cell Polarity Membrane Receptors in Platelets

S.P Comer^1,2, N. Alkazemi^1,2, D. Hamilton^1,2, T. O'Neill³, P. Maguire^1,2,4
Abstract Number: PB0636

Discrepancies in Non-severe Hemophilia A. Experience in a Hemophilia Center in Argentina

E. Sueldo¹, R. Porsella¹, L.C.R. Rossetti², V. Marchione², P. Radic², C. De Brasi², A. Baques¹, M. Arias¹
Abstract Number: PB1169

Discrepancy between Genotype and Phenotype for Factor V Leiden Mutation in Recipients of Liver and Stem Cell Transplantation

J. Rigano¹
Abstract Number: LPB0029

Distinct Clonal Mutation Patterns between JAK2 V617F Positive and CALR-mutated Essential Thrombocythemia

R. Fu¹, D. Liu², H. Xiong², H. Su², H. Li¹, X. Liu¹, F. Xue¹, S. Zhu², R. Yang¹, T. Cheng¹, L. Zhang¹
Abstract Number: PB0149

Distinctive Biomarker Features in the Endotheliopathy of Covid-19 and Septic Syndromes

A.B. Moreno-Castaño^1,2,3, S. Fernandez⁴, M. Palomo^5,2,3, J. Martinez-Sanchez^5,2,3, S. Torramade-Moix^2,3, A. Tellez⁴, H. Ventosa⁴, F. Segui⁴, G. Escolar^1,2,3, E. Carreras^5,3, J.M. Nicolas^4,6, E. Richardson⁷, D. Garcia-Bernal⁸, C. Carlo-Stella⁹, J.M. Moraleda⁸, P. Richardson¹⁰, M. Diaz-Ricart^1,2,3, P. Castro^4,2,6
Abstract Number: PB0870

Disturbed Platelet Activation in Children with ANKRD26-associated Thrombocytopenia

D. Polokhov¹, D. Fedorova¹, A. Pshonkin¹, A. Ignatova¹, E. Ponomarenko¹, M. Aleksenko¹, I. Mersiyanova¹, E. Seregina¹, K. Voronin¹, A. Poletaev¹, E. Raykina¹, M. Panteleev^1,2,3,4, P. Zharkov¹.
Abstract Number: PB0686

Do New Therapies alter the Treatment of Hemophilia Patients?

H. Duda¹, B. Haschberger¹, J. Hesse¹, H. Windecker¹, A. Hilger¹, C. Keipert¹
Abstract Number: PB0210

Do Thrombotic and Bleeding Phenotypes Differ in Patients with Severe COVID-19 Compared to Other Viral Pneumonias in the Context of Extracorporeal Membrane Oxygenation?

A. Weatherill¹, M. Gaspar², M. Passariello³, M. Laffan⁴, S. Ledot³, D.R. Arachchillage²
Abstract Number: PB0200

Does a National Lockdown Affect the Characterises of Deep Vein Thromboses and Patients in the Community?

A. Shahid¹, N. Aden², M. Howard¹, S. Narayanamoorthi¹, T. Khan¹
Abstract Number: PB1174

Does Anticoagulation Affect Outcome of Splenic Vein Thrombosis in Acute Pancreatitis?

L. Vieira¹, S. Lopes¹, R. Pombal¹, R. Neto¹, A. Magalhães¹, M. Figueiredo¹
Abstract Number: PB0172

Does Hydroxychloroquine Prevent Symptomatic Venous Thromboembolism in Patients with Mild to Moderate COVID-19?

P.-M. Roy^1,2,3, V. Dubée^4,5, B. Vielle⁶, O. Blanchet⁷, J.-M. Lemée⁸, R. Dhersin⁴, S. Boucher^9,1, C. Belizna^10,1, G. Urbanski^11,1, O. Sanchez^12,13,3, P. Girard^14,3, A. Elias^15,3, D. Douillet^16,1,3, I. Pellier^17,5, HYCOVID Study Group
Abstract Number: PB0509

Does Pharmacokinetic-guided Prophylaxis with Antihemophilic Factor (Recombinant) Improve Bleeding Rates over Standard Prophylaxis? Real-world Data from the AHEAD German Study

R. Klamroth¹, A. Huth-Kühne², K. Kurnik³, C. Escuriola-Ettingshausen⁴, S. Regensburger⁵, L. Tang⁶, J. Norton⁷, A. Fernandez⁶, J. Oldenburg⁸
Abstract Number: PB0189

Does Thromboelastography Predict Clinical Outcomes in COVID-19?

M. Gaddam¹, A. Wahab², A. Borgert¹, S. Frankki¹, U. Perepu², S. Lentz², L. Rosenstein¹
Abstract Number: PB0926

Don’t Let Bleeding Go Unnoticed – A Global Initiative to Increase Awareness of von Willebrand Disease

F.F. Corrales-Medina^1,2, E. Berntorp³
Abstract Number: PB0469

Dose Selection for Subcutaneous Marzeptacog Alfa (Activated) in Subjects with Factor Vll Deficiency Using Population Pharmacometric Clinical Trial Simulations

A. Faraj¹, S. Desai², L. Neuman², G.E Blouse², T. Knudsen², U.S. Simonsson¹
Abstract Number: PB0458

Dose Selection of Marzeptacog Alfa (Activated) in Children with Hemophilia: A Population Pharmacokinetic Exposure Matching Strategy

A. Faraj¹, R. van Wijk¹, L. Neuman², S. Desai², G.E Blouse², T. Knudsen², U.S. Simonsson¹
Abstract Number: LPB0067

Drastic Decrease in FVIII Response after Repeated Daily Desmopressin Administrations in Peri-operative Non-severe Hemophilia A Patients: Final Results of Tachyphylaxis in the DAVID and Little DAVID Study

L.G.R. Romano¹, L.M. Schütte¹, R.M. van Hest², K. Meijer³, B.A.P. Laros - van Gorkom⁴, L. Nieuwenhuizen⁵, J. Eikenboom⁶, F.C.J.I. Heubel-Moenen⁷, N. Uitslager⁸, M. Coppens⁹, K. Fijnvandraat¹⁰, M.H.E. Driessens¹¹, S. Polinder¹², M.H. Cnossen¹³, F.W.G. Leebeek¹, R.A.A. Mahtôt², M.J.H.A. Kruip¹, On behalf of the SYMPHONY Consortium
Abstract Number: PB0832

Drug Induced Purpura in Autologous Hematopoietic Stem Cell Transplantation – A Case Report

T. Quaresma¹, A. Rodrigues¹, A. Garção¹, C. Malcata², A. Silva Martins³, A. Cristina Alho³, M. Galvão¹
Abstract Number: PB0729

Dual Effect of Hepsin Expression on Tumor Phenotype and Prothrombotic Potential of Colorectal Cancer Cells and Inhibition by Venetoclax

M.C. Rodenas-Bleda¹, J. Peñas-Martínez^2,1, D. Zaragoza-Huesca^2,1, C. Ortega-Sabater^2,1, J. Peña-García³, S. Espín¹, G. Ricote¹, F. Ayala-de la Peña^1,2, G. Luengo-Gil^1,2, A. Nieto¹, F. García-Molina², V. Vicente^1,2, F. Bernardi⁴, H. Pérez-Sánchez³, A. Carmona-Bayonas^1,2, I. Martínez-Martínez¹
Abstract Number: OC 72.4

Durability of Platelet Count Response in Patients Treated with Avatrombopag for Immune Thrombocytopenia (ITP): Post-hoc Results from the Phase 3 Core and Open-label Extension Study

S. Jain¹, M. Wojdyla², C. Bernheisel², S. Kolodny², M. Vredenburg², T. Gernsheimer³
Abstract Number: PB1262

Duration and Treatment Outcomes between Idiopathic and Provoked Non-catheter-Related Axillary and Subclavian Vein Thromboses

A. Sliskovic¹, M. Vrkic Kirhmajer¹, M. Narancic², I. Sabol³, M. Vodanovic¹, A. Boban¹, D. Pulanic¹
Abstract Number: PB1168

Duration of Thromboprophylaxis with Low Molecular Weight Heparins after Cesarean Delivery in Carriers of Leiden Mutation, F5g1691a Genotype

M. Nikolaeva^1,2, K. Shchekleina¹
Abstract Number: PB0534

Dutch Overweight People with Hemophilia Report More Limitations in Activities, but No Association with Sports

O. Versloot¹, E. van Balen², S. Hassan², S. Schols³, F. Leebeek⁴, M. Coppens⁵, J. Eikenboom², L. Hooimeijer⁶, L. van Vulpen¹, C. Smit², M. Driessens⁷, J. van der Net⁸, S. Gouw^5,2, K. Fischer¹, HiN6 steering group
Abstract Number: PB0222

Dynamic Monitoring of Hemostasis and Correction of Heparin Therapy Can Halve the Number of Thrombotic Complications in Patients with Severe COVID-19

F. Ataullakhanov^1,2,3,4,5, S. Shakhidzhanov¹, D. Nechipurenko^4,1,3, I. Serebrisky⁶, S. Karamzin¹, I. Spiridonov¹, D. Zateyshchikov⁷, M. Panteleev^1,3,4,5, V. Mustyatsa^3,1, D. Morozova⁸, E. Koltsova^1,3, E. Seregina^3,1, S. Ratchina⁹, A. Gubkin¹⁰, A. Martyanov^3,1, E. Grishchuk², D. Protsenko¹¹, C. Tsarenko¹², H. Vasilieva¹³, A. Rumyantsev³