ISTH 2021 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB0154

Haematological, Coagulation and Biochemical Abnormalities in Covid-19 Patients in India: Do We Behave Differently?

N. Awasthi¹, V. Tiwari¹, S. Naqvi¹, P. Das¹, S. Aswal¹, N. Husain¹, A. Tripathi¹
Abstract Number: PB0620

Haemophilia A Genotyping in Patients with Discrepancy in FVIII Activity Levels Measured with One-stage and Chromogenic Assays

L. Rossetti¹, V. Marchione¹, M. Arias², E. Sueldo², C.P. Radic¹, B. Ziegler¹, M.M. Abelleyro¹, K. Waisman¹, A. Baqués³, C. De Brasi^1,4
Abstract Number: OC 18.3

Haemostatic Components Are Associated with Risk of Venous Thromboembolism after Lower Leg Trauma

C. Touw¹, B. Nemeth¹, R. van Adrichem¹, W. Lijfering¹, A. van Hylckama Vlieg¹, R. Nelissen¹, T. Lisman², S. Cannegieter¹
Abstract Number: PB0289

Haemostatic Dysfunctions in COVID-19 Infection: A Systematic Review

S. Abegunde¹, A. Adedeji²
Abstract Number: PB0286

Head-to-Head Comparison of Cytokines Storm-induced Coagulopathy in Septic Shock and Covid-19

J. De Poortere¹, M. Dechamps^1,2, P.-F. Laterre³, M. Octave¹, A. Gigion¹, V. Robaux¹, L. Pirotton¹, J. Bodart¹, L. Gerard^1,3, D. Gruson⁴, M.-A. van Dievoet⁴, J. Douxfils⁵, M. Derive⁶, L. Gatto⁷, C. Bouzin¹, D. Castanares-Zapatero^1,3, L. Bertrand¹, S. Horman¹, C. Beauloye^1,8
Abstract Number: PB0572

Health Care Resource Use (HRU) among Adult Persons with Hemophilia A (PwHA) and Concurrent Joint Disease (JD) in the United States

L.E. Markson¹, P.F. Fogarty¹, L. Ban², Y. Chen¹, R. Zaha³, L. Young⁴
Abstract Number: PB0571

Health Care Resource Use (HRU) among Adult Persons with Hemophilia B (PwHB) and Concurrent Joint Disease (JD) in the United States

L.E. Markson¹, L. Young², L. Ban³, Y. Chen¹, R. Zaha⁴, P.F. Fogarty¹
Abstract Number: PB1288

Heavy Menstrual Bleeding: Knowledge and Practice Assessment among Tunisian Primary Care Physicians

E. Hammami¹, I. Helali¹
Abstract Number: PB0283

Hematologic Abnormalities in Moderate Forms of Covid-19

M. Ben Ayed¹, M. Chelli¹, H. Baccouche¹, S. Saffar¹, A. Chakroun¹, S. Mahjoub¹, N. Ben Romdhan¹
Abstract Number: PB0282

Hematologic Parameters of Ghanaian COVID-19 Patients at Diagnosis

D. Fiawoo¹, B. Opoku-Asare², E. Olayemi¹
Abstract Number: PB0350

Hemolysis Interference in the Anti-Xa Heparin Activity Assay

K. Ruby¹, L. Salvatore¹, R. Lomachinsky¹, D. Ornstein^1,2, J. Khan¹
Abstract Number: PB1044

Hemophagocytic Lymphohistiocytosis Complicating Systemic Diseases

I. Chabchoub¹, R. Ben Salah¹, F. Abida², F. Frikha¹, M. Chaari², Z. Bahloul¹
Abstract Number: PB0507

Hemophilia A Patients with Factor Ⅷ Inhibitor Feature Reduced Levels of CD4+CD25+CD127- Treg Cells and Plasma IL-35

Z.Y. Yan¹, Z. Yan¹, H. He¹, Y. Xie¹, L. Wang¹, W. Wu¹, S. Chen¹, Y. Yan¹, J. Yang¹
Abstract Number: PB0635

Hemophilia and Concussion Outcome Study (HeCos): Neurological Status of Children with Hemophilia – Prevalence and Relevance of Mild Traumatic Brain Injury

A. Berghuber¹, C. Bidlingmaier¹, M. Marx¹, S. Lardschneider¹, L. Wiederer¹, M. Olivieri¹, S. Juranek¹, S. von Mackensen², K. Kurnik¹, M. Bonfert¹
Abstract Number: PB0523

Hemophilia Treatment in 2021: Choosing the ‘Optimal’ Treatment Using an Integrative, Patient-orientated Approach to Shared Decision-making between Patients and Clinicians

C. Hermans¹, G. Benson², G. Dolan³, H. Eichler⁴, V. Jiménez-Yuste⁵, C. Königs⁶, S. Lobet¹, M.E. Mancuso⁷, D. Noone⁸, D. Pollard⁹, S. Zupančić Šalek¹⁰
Abstract Number: PB0209

Hemoreologic Disorders in COVID-19 Patients

O. Kostina¹, E. Galova¹, A. Popovicheva¹, L. Sosnina¹, M. Presnyakova¹
Abstract Number: PB0710

Hemorrhagic Adventitious Bursitis of the Foot in a Patient with Congenital Type 3 von Willebrand Disease

R. Gualtierotti¹, S.M. Stella², E. Biguzzi³, S.M. Siboni³, S. Arcudi¹, L.P. Solimeno³, F. Payvandi¹
Abstract Number: PB0900

Hemorrhagic Phenotype in Pediatric Patients with Glanzmann Thrombasthenia (GT)

D. Fedorova¹, E. Seregina¹, A. Poletaev¹, A. Pshonkin¹, P. Zharkov¹
Abstract Number: PB0055

HemosIL Liquid Anti-Xa Apixaban Measurement in Patients with High Risk of Major Bleeding

J. Hammelburger¹, Z. Cao¹, C. Kung¹
Abstract Number: PB0162

Hemostasiological Blood Properties in Patients with COVID-19 Associated Viral Pneumonia

M. Presnyakova¹, E. Galova¹, O. Kostina¹
Abstract Number: PB0272

Hemostasis Abnormalities in Post-COVID-19 Syndrome

M. Noniashvili¹, T. Saralidze¹, T. Svanidze¹, T. Kandashvili¹, I. Mamatsashvili¹
Abstract Number: PB0266

Hemostasis Disorder in COVID-19 Patients: Disseminated Intravascular Clotting (DIC)?

E. Klychnikova¹, K. Popugaev¹, E. Tazina¹, S. Petrikov¹, S. Badygov¹, A. Bulanov¹
Abstract Number: PB0239

Hemostastatic Alterations with Disease Severity in the Early Symptomatic Phase of COVID-19

S. Huber¹, S. Montalvão¹, S. Martins¹, L. da Silva¹, C. Bacchin¹, N. Santos¹, T. Diaz², C. Wroclawsk³, C. Filho³, E. de Paula¹, J. Annichino-Bizzacchi¹
Abstract Number: PB0325

Hemostatic and Thrombogenic Properties of Lyophilized Human Platelets

H. Zhou¹, A. Lee², K. Moskowitz², T. Diacovo¹
Abstract Number: PO121

Hemostatic Defects Associated with IgA Monoclonal Gammopathy

M.C. Shen^1,2, C.-W. Huang¹, G.-M. Lai¹, Y.-H. Shih¹, C.-Y.L. Lin¹, H.-Y. Lin¹, S.-F. Kuo¹, J.-S. Lin¹
Abstract Number: PB0181

Hemostatic Disorders Are Associated with the Course and Outcomes of COVID-19

R.I. Litvinov^1,2, N.G. Evtugina², A.D. Peshkova², S.I. Safiullina^2,3, I.A. Andrianova², R.R. Khismatullin², S.S. Sannikova⁴, S.M. Abdullaeva², A.I. Khabirova², J.W. Weisel¹
Abstract Number: PB0451

Hemostatic Effect of Tranexamic Acid Combined with Emicizumab in Prophylactic Setting in Severe Hemophilia A: A Preclinical Study

Y. Dargaud¹, N. Enjolras², M. Janbain³, R. Bolbos⁴, M. Brevet⁵, J.-C. Bordet²
Abstract Number: PB0435

Hemostatic Evaluation by Global Coagulation Assays in Patients with Acquired Hemophilia A: Analysis of Multi Centers in Japan

M. Takeyama¹, S. Furukawa^1,2, K. Yada^1,3, K. Ogiwara¹, T. Onishi¹, M. Shima¹, K. Nogami¹
Abstract Number: PB0758

Hemostatic Evaluation by Thromboelastography in Patients from a Peruvian Oncologic Center

L.F. Motta Rosada¹, R.M. Rodriguez Torres¹, N.V. Herrera Valverde²
Abstract Number: PO123

Hemostatic Function in Patients with Factor XI Deficiency

L. Montero Martín¹, N. Butta², M.C Vázquez Rodriguez¹, E. Monzón Manzano³, P. Auña³, E.G. Arias Salgado³
Abstract Number: PB1142

Hemostatic Genetic Risk Factors of Aseptic Cerebral Venous Thrombosis

K. Stepanchenko¹, O. Tsymbal¹, A. Zhydkova¹
Abstract Number: OC 50.2

Hemostatic Profile of COVID-19 Convalescent Plasma (CCP) Donors from Bergamo Area

C.J. Tartari¹, G. Milani¹, F. Salvetti¹, M. Marchetti¹, L. Russo¹, A. Vignoli¹, M. Vitali¹, L. Barcella¹, M. Cefis¹, P. Gomez-Rosas¹, F. Schieppati¹, G. Ravasio¹, L. Castellani¹, G. Marchesi¹, E. Sanga¹, D. Romeo¹, A. Falanga^1,2
Abstract Number: OC 67.1

Hemostatic Response is Maintained for up to 5 Years Following Treatment with Valoctocogene Roxaparvovec, an AAV5-hFVIII-SQ Gene Therapy for Severe Hemophilia A

KJ. Pasi¹, S. Rangarajan², T.M Robinson³, W. Lester⁴, E. Symington⁵, B. Madan⁶, M. Laffan⁷, M. Li³, B. Kim³, G.F Pierce⁸, W.Y. Wong³
Abstract Number: OC 59.3

Hemostatic Treatment of Patients with Rare Bleeding Disorders in the Netherlands: Real-life Data from the RBiN Study

D. Maas^1,2, J. Saes^1,2, K. Meijer³, M. Cnossen⁴, R. Schutgens⁵, M. Peters⁶, L. Nieuwenhuizen^2,7, P. den Exter⁸, I. Kruis⁹, W. van Heerde^1,2,10, S. Schols^1,2
Abstract Number: PB0343

Heparin Interference of the Thrombin Generation Assay Can Be Eliminated by Heparinase Treatment

A. Weber¹, M. LLusa², H. Gritsch¹, N.B Binder²
Abstract Number: OC 27.3

Heparin Modulates FV Procofactor Regulatory Region and Susceptibility to APC

F. Ayombil¹, R.M. Camire²
Abstract Number: PB1275

Heparin Therapeutic Range for Five aPTT Reagents in Plasma and One Point of Care

E. Cortina-de la Rosa¹, K.G. Cortés-Cortés¹, M.O. Romero-Arroyo¹, F.A. Grimaldo-Gómez¹, M.M. Salcedo-Hernández¹, Á.A. Arrieta-Alvarado¹, A. Ramírez-Hernández¹, S. Vázquez-Olvera¹, R. Izaguirre-Ávila¹
Abstract Number: PB0127

Heparin-binding Copolymer Completely Reverses the Anticoagulant Effect of Subcutaneously Administered Enoxaparin in Mice

J. Swieton¹, B. Kalaska¹, J. Miklosz¹, S.-I. Yusa², K. Szczubialka³, D. Pawlak¹, A. Mogielnicki¹
Abstract Number: PB0259

Heparin-induced Thrombocytopenia (HIT) during Extracorporeal Membrane Oxygenation (ECMO) in COVID-19: A Case Report

G.A. Altamirano-Solorzano¹, E. Cortina-de la Rosa¹, F.A. Grimaldo-Gomez¹, V.M. Anguiano-Alvarez¹, K.G. Cortes-Cortes¹, M. Porres-Aguilar^2,3, G. Rojas-Velasco¹, R. Izaguirre-Avila¹
Abstract Number: PB0702

Hereditary Haemorrhagic Telangiectasia (HHT) or Rendu-Osler Weber Disease as an Important Rare Haemorrhagic Disorder in Costa Rica: A Report of Costa Rica

L. Salazar-Sanchez¹, K. Leiva-Gabriel¹, B.I. Hernandez-Salazar¹, C. Salazar-Chacon²
Abstract Number: PB1315

Hereditary Thrombophilia in Macedonian Women with in vitro Fertilization Failure

E. Petkovikj¹, R. Grubovic Rastvorceva¹, T. Makarovska Bojadzieva¹, E. Velkova¹, V. Dejanova¹, E. Ristovska¹, S. Useini¹
Abstract Number: PB1164

Heterozygosity for factor V Leiden with a Catastrophic Presentation

R. Pombal¹, L. Vieira¹, S. Lopes¹, R. Neto¹, H. Gomes¹, M. Figueiredo¹
Abstract Number: PO154

Heterozygous FV Leiden Mutation Associated with Multiple Cerebral Venous Thrombosis in Childhood. A Case Report

Y. Larfi¹, N. Ait Hamouda¹, M. Agha¹, D. Dahlouk¹
Abstract Number: PB0001

High Concentration of Symmetric Dimethylarginine is Associated with Low Platelet Reactivity and Increased Bleeding Risk in Patients with Acute Coronary Syndrome

C. Eyileten¹, J. Jarosz-Popek^1,2, D. Jakubik¹, A. Gąsecka³, M. Wolska¹, A. Fitas¹, P. Czajka¹, A. Nowak¹, M. Ufnal⁴, M. Postuła¹, J.M. Siller-Matuła^5,1
Abstract Number: LPB0115

High Impact and Severe Outcomes of Intracranial Hemorrhage (ICH) in an Italian Population of Adult Mild Hemophiliac Patients: Data from the EMO.REC Registry

E. Zanon¹, S. Pasca¹, F. Demartis², A. Tagliaferri³, C. Santoro⁴, I. Cantori⁵, A.C. Molinari⁶, C. Biasioli⁷, A. Coppola³, G. Castaman², S. Linari², M. Luciani⁸, G. Sottilotta⁹, I. Ricca¹⁰, B. Pollio¹⁰, A. Borchiellini¹¹, A. Tosetto¹², P. Simioni¹, F. Peyvandi¹³
Abstract Number: PB0174

High Incidence and Early Presence of arterial thrombotic events in a COVID-19 hospitalized population: an overlooked problem?

M. de Oliveira¹, F. Cubal², J. Oliveira³, E. Cruz¹, M. Coutinho¹, M. Pereira¹, R. Matos¹, N. Pinho¹, L. Moreira¹, N. Seidi¹, S. Morais¹
Abstract Number: PB0936

High Plasma von Willebrand Factor Level is Associated with Increased Risk of upper Gastrointestinal Bleeding in Patients with Chronic Coronary Syndromes Receiving Long-term Antiplatelet Therapy

V. Korobkova¹, A. Komarov¹, O. Shakhmatova¹, A. Dobrovolsky¹, E. Novikova¹, E. Guskova¹, E. Titaeva¹, E. Yarovaya², A. Shuleshova¹, E. Panchenko¹
Abstract Number: PB0030

High Shear Conditions Takes Place at the Edge of the Wound after Human and Mouse Vessel Injury

A. Yakusheva^1,2,3, K. Butov^2,3,4, F. Ataullakhanov^2,3,5, C. Gachet¹, M. Panteleev^2,3,5, P. Mangin¹
Abstract Number: OC 04.1

High Throughput Sequencing for the Molecular Diagnosis of Inherited Platelet Disorders in Spain. Experience of the GEAPC Group

J.M. Bastida^1,2,3,4, M.L Lozano^5,6, R. Benito^2,3,7, A. Rodríguez-Alén⁸, N. Butta⁹, N. Fernández-Mosteirin:¹⁰, T. Sevivas¹¹, A. Marco-Rico¹², N. Revilla¹³, J. Huertas-Aragonés¹⁴, A. Marin-Quílez^2,3,4, V. Palma-Barqueros^5,6,4, S. Marcellini¹⁵, P. Velasco¹⁶, M.d.M. Nieto¹⁷, C. Sierra-Aisa¹⁸, M.N. Alonso¹⁹, M.F López-Fernández²⁰, J.R. González-Porras:^1,2,3, J. Rivera^5,6,4, GEAPC Study Group
Abstract Number: OC 04.2

High-sensitivity Platelet Proteomics Maps the Response to Different Levels of Thrombin

C. Houlahan¹, Y. Kong^2,3, M. Cielesh⁴, M. William^1,5, P. Coleman^6,1, M. Larance⁴, F. Passam^2,3
Abstract Number: PB0688

High-throughput Screening for Pharmacological Enhancers of Mutated Factor VII Activity

E. Andersen^1,2, M.C. Mowinckel^1,2, B. Stavik^1,2, P.M. Sandset^1,2,3, M.E. Chollet^1,2
Abstract Number: PB0970

Highly Reactive Juvenile Platelets Express Higher Levels of GPVI in a Size-related Manner

A. Veninga¹, S. Handtke², B.M.E. Tullemans¹, S.L.N. Brouns¹, A. Greinacher², J.W.M. Heemskerk¹, P.E.J. van der Meijden^1,3, T. Thiele²
Abstract Number: OC 54.3

Histidine-rich Glycoprotein Attenuates Catheter Thrombosis in Rabbits

R.A. Malik^1,2, P. Liao^1,2, J. Zhou^1,2, J.C. Fredenburgh^1,2, R.H. Hussain^1,2, A. Revenko³, J.I. Weitz^1,2
Abstract Number: LPB0050

History of Cancer is Associated with Increased Platelet Activity and Atherothrombosis in Patients with Peripheral Artery Disease

L. Cofer¹, T. Barrett², Y. Xia³, E. Luttrell-Williams⁴, K. Myndzar⁴, K.-K. Wong^5,6, D. Wise⁷, J. Berger^2,8
Abstract Number: PB0842

HIV is Not the Trigger for HIV-associated TTP

M. Meiring¹, M. Khemisi².
Abstract Number: PB0113

HIV-1 and SARS-CoV-2 Both Cause Protein S, but through Different Mechanisms

M.M. Sim¹, H.R. Alfar¹, M. Hollifield¹, D.W. Chung², X. Fu², M. Banerjee¹, X. Li¹, A.C. Thornton¹, J.Z. Porterfield¹, J.L. Sturgill¹, G.A. Sievert¹, M. Barton-Baxter¹, K.S. Campbell¹, J.G. Woodward¹, J.A. Lopez², S.W. Whiteheart¹, B.A. Garvy¹, J.P. Wood¹
Abstract Number: PO118

Homocysteine Exchange in Athletes in the Arctic Region

N. Vorobyeva^1,2, N. Malyshkina²
Abstract Number: PB1285

Hormonal Contraception (HC) and Thrombosis: Identifying the Gaps in Knowledge among Young Woman

Y. Deng^1,2, S. Tierney², A. Geauvreau¹, M. Velez³, M. Othman^1,2
Abstract Number: PB1202

How Common Are Uterine Venous Plexus Thrombi in Women Attending the Gynaecology Clinic?

T. Amin¹, H. Cohen², M. Wong², D. Jurkovic²
Abstract Number: PO170

How to Use the Data about Risk Factors for Thrombosis in Practice

L. Stanciakova¹, K. Chromekova¹, K. Vajdova¹, M. Dobrotova¹, P. Holly¹, M. Brunclikova¹, T. Bolek², M. Samos², P. Kubisz¹, J. Stasko¹
Abstract Number: LPB0026

How to Use Thrombolytic Agents in the Treatment of Neonatal Thrombosis: A Systematic Review

R. Leong¹, J. Patel², N. Samji³, B. Paes^3,4, A.KC Chan⁴, J.-A. Petropoulos⁵, M.D Bhatt⁴
Abstract Number: PB0698

Human Fibrinogen Concentrate for Bleeding Prophylaxis During Surgery in Adult, Adolescent and Pediatric Patients with Congenital Fibrinogen Deficiency: Results from the FORMA-02 and FORMA-04 Clinical Trials

C. Djambas-Khayat¹, S. Lohade², F. D'Souza³, L. Shamanur⁴, O. Zekavat⁵, I. Kruzhkova⁶, B. Schwartz⁷, C. Solomon⁶
Abstract Number: PB0765

Human Myeloperoxidase Enhances Thrombin Induced Phosphatidylserine Exposure in Human Platelets through Tyrosine Kinase/Calcium/Potassium Channels-mediated Pathway

A Kokhan¹, F Balabin^2,3, I Gorudko¹, A Sokolov^4,5, A Sveshnikova^2,3,6, E Shamova¹
Abstract Number: PB0206

Hypercoagulability Detected by Seer Sonorheometry in Covid-19 Patients at Hospital Admission

F.J. López Jaime¹, S. Martín-Téllez¹, A. Doblas-Márquez¹, I. Márquez-Gómez², J. Alemany¹, M. Pérez-Raya¹, A.M. Mena-Santano¹, D.F. Muñoz-López¹, M.I. Muñoz-Pérez¹, I. Fernández-Bello³, A. Montaño¹
Abstract Number: PB0226

Hypercoagulable Rotational Thromboelastometry NaHEPTEM Profile is Related to Mechanical Ventilation Requirement among Critically ill COVID-19 Patients

I. Carboni Bisso¹, I. Huespe^2,3, M. Las Heras¹, E. Prado¹, M. Garbarini⁴, M.S. López^5,6, L. Barrera^5,6, J. Sinner¹, M. Martinuzzo^5,6
Abstract Number: PB0215

Hypercoagulation by Rotational Thromboelastometry (ROTEM) Predicts Mortality in COVID-19: A Prospective Observational Study

L. Almskog¹, A. Wikman², J. Svensson³, C.M. Wahlgren¹, M. Wanecek⁴, M. Bottai⁵, J. van der Linden¹, A. Ågren^1,6
Abstract Number: PB1205

Hypoalbuminemia, Not Proteinuria, Is Associated with Increased Venous Thromboembolism Risk among Primary Glomerulonephritis Patients with Nephrotic Syndrome: A Meta-analysis of Cohort Studies

B.P. Putra¹, F.N. Putra²