ISTH 2021 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1203

Machine Learning and Algorithmic Diagnosis Identification of PatientsTreated by Direct Oral Anticoagulants Using Medico-administrative Databases

J. Emmerich¹, A. Chekroun-Martinot², C. Petri³, R. Sigogne², L. Perray², M. Maravic⁴
Abstract Number: PB0967

Machine Learning-guided Analysis of Adult and Cord Platelet Adhesion Dynamics

J. Sheriff¹, P. Wang¹, P. Zhang¹, Z. Zhang¹, W. Bahou¹, Y. Deng¹, D. Bluestein¹
Abstract Number: PB0388

Main Blood Serum Metabolites Responsible for the Discrimination of Hospitalized Patients with Moderate Symptoms with or without COVID-19

L. Martins¹, S. Martins², E. Braga¹, D. Stanisic¹, S. Montalvão², L. Da Silva², S. Huber², C. Bacchin², N. Santos², T. Diaz³, C. Wroclawski⁴, C. Filho⁴, L. Tasic², J. Annichino-Bizzacchi²
Abstract Number: OC 53.1

Major Adverse Cardiovascular Events Are a Major Cause of Morbidity after Recovery from Immune Thrombotic Thrombocytopenic Purpura

M. Brodsky¹, S. Selvakumar², L. Yanek¹, S. Hussain¹, A. Moliterno¹, R. Brodsky¹, S. Chaturvedi¹
Abstract Number: PB0734

Malignant Clonal Cell Proliferation in Multiple Myeloma and the Hypercoagulable State

T. Indran¹, G. Gerotziafas², J. Fareed³, A. Spencer¹
Abstract Number: PB0131

Management of a Non-vitamin K Antagonist Oral Anticoagulant Associated Bleeding – A Case Report

R. Pombal¹, S. Lopes¹, L. Vieira¹, R. Neto¹, H. Gomes¹, M. Figueiredo¹
Abstract Number: PO136

Management of a Patient with Hemorragic and Thrombotic Risk Factors, a Brazilian Case Report

N.d.F. Centuriao¹, A.A.R. Villarinho¹, V.F. Aranda¹, D.H.C. Campelo¹, R.M.C. Penteado¹, J.C.d.C. Guerra¹
Abstract Number: PO147

Management of Acquired Hemophilia A: A Case-report

J. Cabral¹, M. Afonso¹, L. Costa², B. Malheiro³, M. Calheiros¹, A.P. Barbosa¹, C. Calaza¹, M. Majar³, G. Carvalho³, A. Marques¹
Abstract Number: PO180

Management of Anticoagulation Therapy in Patients with Idiopathic Mondor’s Disease

G. Sottilotta¹, M.G. Fava², L. Turano³, F. Luise⁴, G.M. Nicolo'⁵, V. Oriana¹, A. Piromalli⁴
Abstract Number: PB0790

Management of Antithrombotic Treatment and Thrombohaemorragic Events in Children under Berlin Heart Excor Devices

M. Arguello-Tomas¹, R. Gomez-Antonio¹, M.J Santiago¹, G. Pérez Rus^1,2, J.L. Diez-Martin^2,3,1, C. Pascual Izquierdo^1,3
Abstract Number: PB0081

Management of Bleeding and Urgent Invasive Procedures in Patients Treated with Direct Oral Anticoagulants: An Observational Study over a Five-year Perio

A. Pontis^1,2, A. Mansour^2,3, A. Maurice³, C. Rousseau⁴, F. Nédelec-Gac¹, P. Guéret¹, L. Soulat⁵, P. Jégo⁶, C. Ecoffey³, I. Gouin-Thibault^1,2,7
Abstract Number: PB1092

Management of Cancer Associated Thrombosis in France: A National Survey in Vascular Disease and Supportive Care Specialists

I. Mahé¹, C. Chapelle², S. Laporte³, L. Bertoletti⁴, P. Mismetti⁴, G. Meyer⁵, D. Mayeur⁶, G. Mahé⁷, F. Couturaud⁸
Abstract Number: PB0296

Management of Clot in Transit in a Postpartum COVID-19 Patient

A. Peruri¹, A. Kadl¹, C. Ennen¹, L. Wilkins¹, R. Ramcharitar¹, N. Teman¹, A. Sharma¹, A. Mihalek¹, L. Man¹
Abstract Number: PB0203

Management of COVID-19 Related Venous Thromboembolism – Data from Ljubljana Registry

G. Tratar¹, A. Mavri¹, T. Vižintin Cuderman¹, N. Vene¹, M. Žitko¹, A. Rehberger Likozar¹
Abstract Number: PB0789

Management of Iliofemoral Deep Vein Thrombosis (DVT) in Pediatric Patients in the Context of May-Thurner Syndrome (MTS)

V. Patel¹, N. Stein², F. Elias³, A.K. Chan⁴, M. Bhatt⁴
Abstract Number: PB0659

Management of Infusion Reactions: Lessons from the Phase 3 HOPE-B Gene Therapy Trial of Etranacogene Dezaparvovec in Adults with Hemophilia B

M. Recht¹, F.W. Leebeek², W. Miesbach³, N.S Key⁴, S. Lattimore¹, G. Castaman⁵, E.K. Sawyer⁶, D. Cooper⁶, V. Colletta⁶, S.W. Pipe⁷, HOPE-B Investigators
Abstract Number: PB0043

Management of Intentional Low Molecular Weight Heparin Overdose: The McMaster University Experience

C. Lu¹, M.A Crowther¹, P.L Gross^1,2, S.M Bates^1,2, S. Mithoowani¹
Abstract Number: LPB0077

Management of Localized Intravascular Coagulopathy with Rivaroxaban in Children with Venous Malformations: Report of 6 Cases

F.B. Belen Apak¹, F. Nabili², F. Sarialioglu¹
Abstract Number: OC 57.1

Management of Patients with Venous Thromboembolism and a High Recurrence Risk Estimated by the Vienna Prediction Model

L. Eischer¹, H. Šinkovec², P. Gressenberger³, T. Gary³, M. Brodmann³, G. Heinze², P.A. Kyrle¹, S. Eichinger¹.
Abstract Number: LPB0047

Management of Peripartum Anticoagulation in Women with Venous Thromboembolism: An International Survey of Clinical Practice

C. Simard¹, I. Malhamé², E. Rey³, M.P. Carson⁴, V. Tagalakis⁵
Abstract Number: PO179

Management of Venous Thrombosis in Non-Hodgkin Lymphoma

V. Musteata¹
Abstract Number: OC 69.1

Management Practices of Catheter-related Arterial Thrombosis in Children and Neonates: Results of a Multinational Survey

M. Rizzi¹, C.H. Van Ommen², M. Albisetti³, On behalf of the International Pediatric Thrombosis Network (IPTN)
Abstract Number: NUR 01.5

Managing Outpatients on Vitamin K Antagonists (VKAs) during the COVID-19 Pandemic in a Tertiary Referral Hospital

C. O'Leary^1,1, V. Silvari¹, C. Browne¹, P. O'Flynn¹, P. Chappell¹, C. Duggan¹, M. Crowley¹
Abstract Number: OC 17.1

Mapping Gene and Gene Pathways Associated with Coronary Artery Disease: A CARDIoGRAM Exome and Multi-ancestry UK Biobank Analysis

P. Hariharan¹, J. Dupuis²
Abstract Number: LPB0100

Mapping Prothrombin Binding on Pseutarin C by Site-directed PEGylation

F.I. Ustok¹, J.A. Huntington¹
Abstract Number: PB0966

MAS9 – A Novel Small Molecule Inhibitor of the CLEC-2-Podoplanin Interaction

M.A. Sowa¹, J. van Groningen², Y. Di³, J.M. Gibbins¹, Á. García⁴, A.Y. Pollitt¹
Abstract Number: PB0031

Mass Cytometry Analysis of Venous Thrombi Demonstrates Key Roles for VWF Interactions in Inflammation-associated DVT

S.J. Choi¹, M. Cormier¹, L. Rapkin², C. Hindmarch³, D. Lillicrap¹
Abstract Number: PB1274

May-Thurner Syndrome-associated Deep Vein Thrombosis: Is Oral Anticoagulation the Novel Approach?

F.A. Lo¹
Abstract Number: PB0351

Measurement of Factor VIII in the Presence of Emicizumab Is dependent on the chromogenic assay selected for use

M. Byrne¹, M. Doyle¹, K. Ryan¹, M. Lavin¹, J.S O'Donnell¹, N.M O'Connell¹
Abstract Number: OC 51.4

Measurement of von Willebrand Factor Levels via Fiber Optic-surface Plasmon Resonance

B. Calcoen¹, C. Dekimpe¹, M. Jacquemin², C. Tersteeg¹, K. Vanhoorelbeke¹, S. De Meyer¹
Abstract Number: PB0679

Measuring the Chromogenic FVIII Mimetic Activity of the New Bispecific Antibody, Mim8, in Artificially Spiked Severe Haemophilia A Plasma

A. Bowyer¹, M. Ezban², S. Kitchen¹
Abstract Number: PB0680

Measuring the FVIII Mimetic Activity of the New Bispecific Antibody, Mim8, in Severe Haemophilia A Plasma Using APTT and One-stage FVIII Assays

A. Bowyer¹, M. Ezban², S. Kitchen¹
Abstract Number: PO132

Mechanical Prosthetic Valve Thrombosis in COVID-19 Infection: Case Report

N. Diaconu¹, D. Lupu¹, T. Cuzor¹, A. Grosu¹
Abstract Number: LB 02.3

Mechanism of the development of thrombotic thrombocytopenia in Covid-19 infected patients and after vaccination

T.H. Nguyen¹,², L.-Y. Chen¹,³, N. Khan⁴,⁵, A. Lindenbauer⁶, D. Heinrich⁴,²
Abstract Number: OC 22.4

Mechanisms Coupling Fibrinogen to Colitis Pathogenesis

B.K. Sharma¹, R. Kudira², L. Rosenfeldt¹, B. Gourley³, O. Milburn⁴, D. Haslam⁴, M. Watanabe-Chailland⁵, L. Romick-Rosendale⁵, M. Flick⁶, J. Palumbo¹
Abstract Number: PB0959

Medium Plate Volume as a Predictor of Plate Engraftment Time in Patients with Bone Marrow Transplant

J.A. Avila Rueda¹, C. Duboscq¹, J. Ceresetto¹, S. Palmer¹, K. Oliveros¹, S. Rivarola¹, A.M. Cantillo¹, M. Carreras¹, L. Zapata¹, M.C. Sernaque¹, N. Flegler¹, O.R. Oscar Rabinovich¹, C. Shanley¹, M. Quarchioni¹, E. Bullorsky¹, G. Stemmelin¹
Abstract Number: PB0836

Melanoma Triggers Severe Thrombotic Thrombocytopenic Purpura and Results in a High Mortality Rate in adamt13^-/- Zebrafish

L. Zheng¹, L. Cao², X.L. Zheng¹
Abstract Number: PB0585

Mental Health Status of Hemophilia Carriers in China

D. Cui¹, Q. Hu¹
Abstract Number: PB0856

Minimal Role of the Alternative Pathway in Complement Aactivation by HIT Immune Complexes

A. Barnes¹, S. Khandelwal¹, S. Sartoretto¹, S. Myoung¹, S. Francis¹, G. Lee¹, L. Rauova², D. Cines³, J. Skare⁴, B. Garcia⁵, G. Arepally¹
Abstract Number: PB0024

miR-19a-3p Predicts Stroke Severity and miR-186-5p Might Be a Diagnostic Biomarker in Ischemic Stroke Patients with Hyper Platelet Reactivity

C. Eyileten¹, D. Jakubik¹, J. Jarosz-Popek^1,2, P. Czajka¹, M. Wolska¹, A. Fitas¹, A. Nowak¹, Z. Wicik³, D. Mirowska-Guzel¹, A. Członkowska⁴, M. Postuła¹
Abstract Number: PO183

Misdiagnosing Protein C and Protein S Deficiency

C. Peixoto¹, Á. Beleza¹, M. Galvão¹, A. Freixo¹, T. Quaresma¹, J. Amorim¹, M.M. Deveza¹
Abstract Number: PB0453

Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models

N. Le Moan¹, L. Kelly¹, E. Merle², P. Descargues², N. Gaudenzio², H. Gagnon³, A. Chatterji¹, G.E. Blouse¹
Abstract Number: PB0894

Modelling Studies to Characterize a Novel Disease-causing Variant in the GP1BA Gene Related to Bernard Soulier Syndrome

D.M Primrose¹, A.I. Woods², M.F Alberto³, J. Paiva³, M. Asencio³, M.M Casinelli³, A.N Blanco³, A. Sánchez-Luceros^3,2
Abstract Number: PB0949

Modern Diagnosis of von Willebrand Disease in Children in Russia: Experience in Centralized Diagnostics

A. Poletaev¹, E. Seregina^1,2, D. Fedorova¹, P. Zharkov¹
Abstract Number: PB0974

Modification of Platelet Characteristics and Hemostasis in Children with Inflammatory Bowel Diseases under Hyperbaric Oxygenation

A. Popovicheva¹, A. Martusevich¹, E. Fedulova¹, I. Neshchetkina¹
Abstract Number: OC 71.4

Modulation of the Procoagulant and Cytotoxic Effects of Histones by Glycosaminoglycans

N. Sharma^1,2, S. Sohrabipour¹, D. Dwivedi^1,2, P. Liaw^1,2
Abstract Number: PB0942

Molecular Heterogeneity in von Willebrand Disease in North Indian Patients

R. Sharma¹, M. Jamwal¹, N. Kumar¹, H.K. Senee¹, C. Hans¹, D. Bansal¹, A. Trehan¹, P. Malhotra¹, R. Das¹, J. Ahluwalia¹
Abstract Number: LPB0111

Molecular Interactions of Coagulation Factor XIII B Subunit

K. Pénzes¹, B. Bécsi², F. Erdődi², L. Muszbek¹
Abstract Number: PB0063

Monitoring Heparin: Stability of Two Different Anti-Xa Assays in Citrated vs CTAD Tubes

T. Sinegre¹, M. Gremillet¹, V. Fourneyron¹, M. Tillier¹, A. Trayaud¹, L. Talon¹, A. Lebreton¹
Abstract Number: PB0694

Monitoring Rare Bleeding Disorders and their Response to Therapeutic Treatments with a Microchip Flow-chamber Assay

P. Acuña¹, E. G. Arias-Salgado¹, E. Monzón Manzano¹, M. Martín Salces¹, M.T. Álvarez Román¹, M.I. Rivas Pollmar¹, S. García Barcenilla¹, T. Cebanu¹, E. Gonzalez Zorrilla¹, N. Butta¹, V. Jiménez Yuste¹
Abstract Number: OC 77.1

Monocyte-macrophage Synthesis of FVII Contributes to the Development of Atherosclerosis

R. Wolz¹, W. Ruf^1,2
Abstract Number: LPB0112

Monocytes Expose Factor XIII-A and Stabilize Thrombi against Fibrinolytic Degradation

F. Alshehri^1,2
Abstract Number: PB0461

Monocytes Express Different Cytokines upon Stimulations with a Variety of FVIII but Not FIX Concentrates

S. Scatigna¹, A. Orlowski¹, E. Salzmann-Manrique¹, C. Königs¹, A. Schmidt¹
Abstract Number: PB0462

Monocytes Show Differences in Cytokine Expression after Stimulation with FVIII Concentrates Compared to FIX or MOG

S. Scatigna¹, A. Orlowski¹, E. Salzmann-Manrique¹, C. Königs¹, A. Schmidt¹
Abstract Number: OC 68.1

Morphological and Functional Alterations in Endothelial Colony-forming Cells from Recovered COVID-19 Patients

J. Davila-Moreno^1,2, V. Manuel-Domínguez¹, A. Chávez-González³, A. Majluf-Cruz¹, J.A. Alvarado-Moreno¹
Abstract Number: PB0150

Multi-organ Vascular Defects and General Morphological Changes in a Murine Model of SARS CoV-2 Infection

M. Paidas¹, A. Mohamed¹, A. Saad², A. Jayakumar¹
Abstract Number: OC 19.1

Multi-phenotype Analysis of Hemostatic Factors with Venous Thromboembolism Reveals Novel Genetic Associations

G. Temprano-Sagrera¹, P.S de Vries², M. Martín-Bórnez¹, S.M Damrauer^3,4,5, N.L Smith^6,7,8, M. Sabater-Lleal¹, on behalf the CHARGE and INVENT Consortia.
Abstract Number: OC 45.1

Multicenter Performance Evaluation and Reference Range Determination for the Quantitative Assessment of Factor XI Activity by One-stage Factor Assay on the Cobas t 711 Analyzer

M. Büchsel¹, J. Creaghan², U. Geisen¹, P. Jilma³, R. Jones², S. Kitchen², G. Rozsnyai⁴, P. Quehenberger³
Abstract Number: PB0366

Multicenter Performance Evaluation and Reference Ranges for the Quantitative Determination of Factor XII Activity by One-stage Factor Assay on the Cobas t 711 Analyzer

M. Büchsel¹, J. Creaghan², U. Geisen¹, P. Jilma³, R. Jones², S. Kitchen², G. Rozsnyai⁴, P. Quehenberger³
Abstract Number: PB0133

Mutagenesis Study Reveals Factor X Gla-domain Residues Critical for Initiation of the Clotting Cascade

D. Paul¹, S.M. Medfisch¹, R.C. Bailey¹, J.H. Morrissey¹
Abstract Number: LPB0065

Mutation of Sortase A Cleavage Site and Potential Impact on Human Plasminogen Binding by PAM

B. Readnour¹, Y. Ayinuola¹, V. Ploplis¹, F. Castellino¹
Abstract Number: PB0905

Mutations at p.C1190 in VWF D3 Retain VWF in the ER in VWD 2A Patient-derived ECFCs

I. Van Moort¹, P.E. Bürgisser¹, M.W. Swinkels¹, S. Yildiz¹, F. Atiq¹, F.W. Leebeek¹, R. Bierings¹, for the SYMPHONY consortium
Abstract Number: OC 01.3

Myeloid Par2 Deficiency Protects Mice during IAV Infection

R.C. Gunther¹, E. Camerer², N. Mackman¹, S. Antoniak¹